Abstract: A traditional Chinese medicine composition for treating dermatophytosis and bromhidrosis, which is prepared from radix sophorae flavescentis and peristrophe japonica, has synergistic interaction and anti-fungal effects, and is not easy to produce drug tolerance. After performing compatibility of extracts of matrine and peristrophe japonica, dermatophytosis and bromhidrosis can be treated, and multiple external preparations can be prepared.
Abstract: The present invention provides a composition that can preserve biomaterials. The biomaterial preservation composition of the present invention includes a micro bubble.
Type:
Grant
Filed:
May 31, 2019
Date of Patent:
September 10, 2024
Assignees:
AICHI MEDICAL UNIVERSITY, SUMITOMO SEIKA CHEMICALS CO., LTD.
Abstract: Methods of producing, compositions containing, and methods for administering curcumin, and particularly extracts obtained from a laser irradiated rhizome of Curcuma longa having an enhanced antimicrobial activity. An ethanolic extract of the laser irradiated rhizome of Curcuma longa exhibits increased levels of bisdemethoxycurcumin and curcumin, as well as of alpha-curcumene, (-)-zingiberene, caryophyllene, and beta sesquiphellandrene as compared to those of an ethanolic extract from a Curcuma longa rhizome not irradiated by a laser.
Abstract: This disclosure relates to extracts from the Anacardiaceae (cashew plant family) and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the fruit of a Schinus plant. In certain embodiments, the disclosure relates to methods of treating or preventing bacterial infections, acne, and other related uses.
Type:
Grant
Filed:
March 14, 2023
Date of Patent:
September 10, 2024
Assignee:
EMORY UNIVERSITY
Inventors:
Cassandra L. Quave, James Lyles, Gina Porras-Brenes, Huaqiao Tang
Abstract: Embodiments herein relate to compositions herein can include one or more of a tomato extract, a rhubarb extract, a garlic extract, a cashew shell composition, and a saponin composition, wherein the composition prevents or reduces methanogenesis in animals. Embodiments herein also relate to compositions including one or more of glycoalkaloids, saponins, anthraquinones, anacardic acid, and allicin and methods for using the same for mitigating methanogenesis in animals. In an embodiment, a composition can include glycoalkaloids, such as ?-tomatine, that can prevent methanogenesis. In an embodiment, a method of processing animal feed is included. In an embodiment, a method of treating an animal to reduce methanogenesis is included. Other embodiments are also included herein.
Type:
Grant
Filed:
September 24, 2021
Date of Patent:
September 3, 2024
Assignee:
SarTec Corporation
Inventors:
Larry C. McNeff, Clayton V. McNeff, Peter G. Greuel, Bingwen Yan, Anthony Roy Jenks
Abstract: Provided herein are micronized placental compositions composed of micronized placental tissue component, such as amnion or chorion and/or filler bound to one or more chelating agents, which in turn are optionally bound, reversibly, to pharmacologically active metal ions. Further provided are methods of making and using the placental compositions. The compositions have numerous therapeutic applications.
Abstract: A transmucosal psychoactive alkaloid composition including a psychoactive alkaloid extract or synthetic psychoactive alkaloid. The alkaloids in the extract are predominantly dephosphorylated rather than phosphorylated. The transmucosal psychoactive alkaloid composition also includes a mucoadhesive polymer, a carrier, and optional further excipients. The non-ingestive composition may be taken orally through the mucosa. A process for obtaining an oral transmucosal psychoactive alkaloid composition includes dephosphorylating the alkaloid during extraction, purifying the extracted alkaloid and standardizing to a specific concentration by adding measured quantities of excipients.
Type:
Grant
Filed:
November 20, 2023
Date of Patent:
August 27, 2024
Assignee:
Psilo Scientific, Ltd.
Inventors:
Ryan Moss, Benjamin Lightburn, Lisa Ranken
Abstract: The invention relates to various compositions for improving exercise performance and/or recovery. The invention also relates to methods of using these compositions and kits including these compositions to improve exercise performance and/or recovery.
Abstract: A method of treatment of plasma with a physiologically compatible spray dry stable acidic substance (SDSAS) prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compostions related to plasma dried by the methods of the present invention.
Type:
Grant
Filed:
October 22, 2021
Date of Patent:
August 20, 2024
Assignee:
Velico Medical, Inc.
Inventors:
Qiyong Peter Liu, Junqing Cui, Rud Karly Lucien, Ryan Carney, Jihae Sohn, Michelle Arya, Abdul W. Khan
Abstract: The present disclosure relates to the synergistic combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, a cofactor of the enzyme, and a glucan. The present disclosure also relates to the synergistic combination of sulforaphane or a derivative thereof and a glucan. The present disclosure also relates to the synergistic combination of a broccoli extract or powder and a glucan. The glucan may be a ?-glucan. The glucan may be provided in a mushroom extract or powder selected from one or more of a maitake, a shiitake, or a reishi mushroom. Compositions and methods relating to these combinations are described.
Type:
Grant
Filed:
February 18, 2021
Date of Patent:
August 20, 2024
Assignee:
NUTRAMAX LABORATORIES, INC.
Inventors:
Brian Cornblatt, Grace Cornblatt, Anton Bzhelyansky, Robert Henderson
Abstract: A composition for supporting metabolism or the endocrine system of a subject includes transfer factor and one or more support components. The transfer factor is useful for preventing, mitigating the effects of, or reversing autoimmunity, as well as for preventing, mitigating the effects or, or reversing oxidative stress. The one or more support components may prevent misregulation of or facilitate regulation of metabolism or endocrine system of the subject. A support or treatment method includes administering transfer factor to a subject, with or without one or more support components.
Type:
Grant
Filed:
May 20, 2005
Date of Patent:
August 13, 2024
Assignee:
4Life Patents, LLC
Inventors:
Calvin W. McCausland, Brent Vaughan, William J. Hennen, David A. Lisonbee
Abstract: The invention relates to the alkaloids mesembranol or mesembrenol, or pharmaceutical acceptable salts or complexes thereof, for use in the prophylaxis or treatment of a disease that responds to treatment with an AMPA (?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor antagonist. The prophylaxis or treatment attenuates AMPA mediated neurotransmission in the hippocampus of a subject.
Abstract: Presented herein, in certain aspects, are cell-free therapeutic composition derived from human amniotic fluid (HAF) and uses thereof for the prevention and treatment of selected diseases and disorders.
Abstract: Methods and compositions for treating aging-related diseases as well as liver regeneration, prevention of liver degeneration, and maintenance of liver are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing disease.
Abstract: A formulation of curcuminoid mixture having curcumin, demethoxycurcumin and bisdemethoxycurcumin and an essential oil of turmeric having 45% Ar-turmerone. The formulation gives enhanced bioavailability of bisdemethoxycurcumin, demethoxycurcumin and curcumin for up to 10 hrs. The curcuminoid mixture has curcumin, demethoxycurcumin and bisdemethoxycurcumin in a weight/weight ratio ranging from about 0.8:1:1 to about 1:1.1:1.2. A process of preparing a formulation of curcuminoid mixture having curcumin, demethoxycurcumin and bisdemethoxycurcumin in 0.8:1:1 to 1:1.1:1.2 weight/weight ratio and an essential oil of turmeric having 45% Ar-turmerone. A formulation for improved biological activity and bioavailability and tissue distribution of curcumin, demethoxycurcumin and bisdemethoxycurcumin.
Abstract: Disclosed is a method for moisturizing skin in need thereof, the method comprising topically applying to the skin a composition that includes effective amounts of an extract from Echinacea purpurea, an extract from Silybum marianum, and glycerin, wherein topical application of the composition activates human cannabinoid receptor type 2 and inhibits fatty acid amide hydrolase activity in the skin and treats the skin.
Abstract: An enhanced food composition in the form of a frozen or refrigerated food is described, the enhanced food composition comprising a nitrate-containing vegetable, such as beetroot, effectively mixed with a salt content of a food component of the food composition at a specified ratio. The enhanced food composition has the effect to prevent an increase in blood pressure while masking the bad taste of the nitrate-containing vegetable.
Abstract: The current disclosure relates to a culture medium, different methods to generate adult-like cardiomyocytes from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC) using the medium, in particular from stem cells that differentiated into (foetal) cardiomyocytes, and to kits comprising the medium, or the medium together with differentiated (foetal) cardiomyocytes derived from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC).
Abstract: Compositions and methods are presented that substantially increase levels of BDNF in blood, and even more pronouncedly exosomal BDNF levels. Suitable compositions include whole coffee fruit extracts and powders that are orally administered at relatively low dosages.