Abstract: A liquid electrolyte, for an electrochemical gas sensor for detecting NH3 or gas mixtures containing NH3, contains at least one solvent, one conductive salt and/or one organic mediator. The conductive salt is an ionic liquid, an inorganic salt, an organic salt or a mixture thereof. The electrolyte preferably is comprised of (I) water, propylene carbonate, ethylene carbonate or a mixture thereof as solvent; (ii) LiCl, KCl, tetrabutylammonium toluenesulphonate or 1-hexyl-3-methylimidazolium tris(pentafluoroethyl)trifluorophosphate as conductive salt; and (iii) tert-butylhydroquinone or anthraquinone-2-sulphonate as organic mediator.

Abstract: An anticorrosion test method for a coated metallic material may include: a preparation step of adding an artificial flaw at two positions of the coated metallic material; a first measurement step of measuring a size of the artificial flaw; a connection step of electrically connecting the artificial flaws at the two positions by an external circuit via water-containing materials; an energization step of energizing a steel sheet to produce a bulge of an electrodeposition coating film; a second measurement step of measuring size of the bulge of the electrodeposition coating film; a calculation step of calculating a degree of progress of corrosion of the coated metallic material; and a correction step of correcting the degree of the progress of the corrosion.

Abstract: The present invention is directed to membranes, sensors, systems and process for the detection of magnesium ions in protein-containing samples. The novel membranes, sensors, systems, and processes are based upon the discovery that the lipophilicity of the plasticizer (or blend of plasticizers) utilized in the formulation of magnesium ion selective membranes for clinical use is inversely proportional to the sensitivity of the plasticizer(s) and directly proportional to the use life thereof.

Abstract: A solid state gel for use in a pH sensor comprises a reaction product of water, a buffer system for adjusting pH of the gel when in a liquid state, polyethylene glycol or its derivatives as a gelling agent and a salt wherein the water, the buffer, the polyethylene glycol and a reference electrolyte salt when mixed while in a liquid state form a mixture that was subjected to Gamma irradiation to form the reaction product.

Abstract: A sensor interface circuit (5) for an amperometric electrochemical sensor (3). The circuit includes: a current-to-voltage converter (9, Rf) connected to a first terminal (WRK) of the sensor (3) for converting an electric current through the sensor (3) to a voltage at an output terminal (10) of the current-to-voltage converter (9, Rf); a first amplifier (7) connected between a second terminal (REF) and a third terminal (CNTR) of the sensor (3) for maintaining a substantially fixed voltage difference between the first and second terminals (WRK, REF) of the sensor (3); a power supply (11) for powering the voltage converter (9, Rf) and for powering a first portion (31) of the first amplifier (7); and a negative voltage converter (17) configured to power a second portion of the first amplifier (7) through its low-side supply terminal (41), while a high-side supply terminal (39) of the second portion of the first amplifier (7) is configured to be connected to the power supply (11).

Abstract: A pH measuring device configured to measure a pH of a target liquid includes a main body block including a cavity, a supply line communicating with the cavity, a first drain line communicating with the cavity, and a target liquid supply valve configured to adjust a supply of the target liquid into the supply line. The main body block has an integral structure in which a pH sensor is supported such that the pH sensor is in contact with the target liquid within the cavity.

Abstract: An electrochemical oxygen sensor includes a sensing surface having a working electrode and a reference electrode, a hydrophilic layer formed from an oxygen diffusion-limiting layer emulsion overlaying the working electrode and a hydrophobic membrane formed from a hydrophobic solution disposed over the hydrophilic layer. The hydrophilic layer contains an epoxy network and a hydrophilic polymer. The hydrophobic layer contains an acetate copolymer and a cross-linking agent that reacts with the liquid epoxy resin in the hydrophilic layer forming the epoxy network where the hydrophobic member is water vapor and oxygen permeable.

Abstract: Methods and apparatus providing for the isolation of an unknown mutation from a sample comprising wild type nucleic acids and mutated nucleic acids through the application of time-varying driving fields and periodically varying mobility-altering fields to the sample within in an affinity matrix.

Abstract: A system for measuring corrosion includes a first electrode configured to be connected to a first structure and a second electrode configured to be connected to a second structure. The first and second structures are galvanically-coupled together, and the first and second structures are made of different materials. A chamber is configured to run through one or more cycles while the first electrode, the first structure, the second electrode, and the second structure are positioned inside the chamber. A measurement device is configured to receive data from the first and second electrodes and to measure one or more parameters based at least partially upon the data. A level of corrosion on the first structure, the second structure, or both is configured to be determined based at least partially upon the one or more parameters.

Abstract: Techniques for measuring sequences of nucleic acids are provided. Time-based measurements (e.g., forming a histogram) particular to a given sequencing cell can be used to generate a tailored model. The model can include probability functions, each corresponding to different states (e.g., different states of a nanopore). Such probability functions can be fit to a histogram of measurements obtained for that cell. The probability functions can be updated over a sequencing run of the nucleic acid so that drifts in physical properties of the sequencing cell can be compensated. A hidden Markov model can use such probability functions as emission probabilities for determining the most likely nucleotide states over time. For sequencing cells involving a polymerase, a 2-state classification between bound and unbound states of the polymerase can be performed. The bound regions can be further analyzed by a second classifier to distinguish between states corresponding to different bound nucleotides.

Abstract: An electrolyte concentration measurement device includes: an ion-selective electrode supplied with the liquid; a reference electrode serving as a reference for a potential; a potential measuring unit configured to acquire a potential of the ion-selective electrode; a concentration calculation unit configured to calculate a concentration of ions contained in the liquid based on the potential acquired by the potential measuring unit; a potential monitoring unit configured to monitor a potential of the ion-selective electrode and generate a potential response curve; a timing signal acquisition unit configured to acquire a timing signal related to a timing of various operations; and a potential response curve analysis unit configured to detect an abnormality sign of a device based on a relationship between the potential response curve and the timing signal.

Abstract: An electrochemical oxygen sensor with a long service life is provided. The electrochemical oxygen sensor according to the present invention includes a positive electrode, a negative electrode, and an electrolyte solution, and the negative electrode contains tin or a tin alloy, the electrolyte solution is an aqueous solution obtained by dissolving at least citric acids, the aqueous solution contains an alkali metal, a total content of the citric acids in the electrolyte solution is 2.1 mol/L or higher, a content of the alkali metal in the electrolyte solution is 0.1 to 1.6 times the total content of the citric acids, the electrolyte solution has a pH of 3.9 to 4.6, and when a volume of the electrolyte solution is x (ml) and a content of tin contained in the negative electrode is y (g), x/y?0.3 (ml/g) holds true.

Abstract: A capillary array electrophoresis (CAE)-chemiluminescence (CL) detection coupled system includes a high-voltage power supply, a capillary array, an array channel CL reaction tank, a CAE sample tank, a CAE detection tank, a chemiluminescent reagent delivery unit, a multi-channel detection unit, and a data acquisition and processing unit. An inlet end of the capillary array is connected to the CAE sample tank. An outlet end of the capillary array is connected to the array channel CL reaction tank, and is further connected to the CAE detection tank.

Abstract: To sense the translocation of a molecule through a nanopore, there is directed to an inlet of the nanopore, having a nanopore fluidic resistance, RP, a molecule disposed in a cis fluidic ionic solution having a cis fluidic access resistance, RC. The molecule is caused to translocate through the nanopore from the inlet of the nanopore to an outlet of the nanopore and to a trans fluidic ionic solution having a trans fluidic access resistance, RT. The trans fluidic access resistance, RT, is of the same order of magnitude as the nanopore fluidic resistance, RP, and both RT and RP are at least an order of magnitude greater than the cis fluidic access resistance, RC. An indication of local electrical potential is produced at a site within the nanopore sensor that is on the trans fluidic ionic solution-side of the nanopore, to sense translocation of the molecule through the nanopore.

Abstract: A biosensing chip is provided, including a substrate having a photoelectric conversion material, and an electrode disposed on the substrate and including two contact portions and an electrode pattern, wherein the photoelectric conversion material is a monocrystalline silicon material, and the electrode pattern includes micro-electrodes in the form of interdigitated sawtooth. The biosensing chip and the method using the same may distinguish a lesion site of cancer cells and the degree of cancer lesions.

Abstract: Sensors having an advantageous design and methods for fabricating such sensors are generally provided. Some sensors described herein comprise pairs of electrodes having radial symmetry, pairs of nested electrodes, and/or nanowires. Some embodiments relate to fabricating electrodes by methods in which nanowires are deposited from a fluid contacted with a substrate in a manner such that it evaporates and is replenished.

Abstract: A method and a sensor for detecting L-arginine are provided. The method includes synthesizing ferrocene-functionalized hexadecapeptide dithiocyclopentane (FC-P16 Peptide), preparing a polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE), detecting L-Arg and other steps. The results show that the polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE) exhibits excellent electrochemical response properties to L-Arg. In 10 mmol/L phosphate-buffered saline (PBS, pH=7.4), the DPV response peak current of the polypeptide composite membrane-modified electrode has an excellent linear relationship with the L-Arg concentration of 1.0×10?13 mol/L to 1.0×10?7 mol/L, with a detection limit of 1.0×10?13 mol/L. With prominent reproducibility, repeatability and selectivity, the modified electrode has potential application in life science and nutritional health.

Abstract: In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.

Abstract: Provided is a capillary array unit configured to facilitate attaching/detaching operation. A capillary array unit includes a capillary, a load header provided at one end of the capillary, a capillary head provided at the other end of the capillary, a detection section provided at a portion of the capillary, and a holder holding the capillary. The holder includes a first holding section holding the capillary in a curved shape, a second holding section linearly holding the capillary, and a guide to move the second holding section in a predetermined direction.

Abstract: A system includes a system housing including an inlet, at least one gas sensor responsive to a first analyte gas other than oxygen within the system housing and in fluid connection with the inlet, and a sensor responsive to oxygen within the system housing and in fluid connection with the inlet. The sensor responsive to oxygen is formed to be chemically separate from the at least one gas sensor responsive to the first analyte gas other than oxygen. The sensor responsive to oxygen is responsive to a change in the concentration of oxygen arising from creation of a driving force in the vicinity of the inlet to provide an indication of a state of a transport path between the inlet of the system and the at least one gas sensor responsive to the first analyte gas other than oxygen.