Patents Examined by Alexander S Noguerola
  • Patent number: 11327043
    Abstract: A gas sensor element includes: an element base being a ceramic structure including a sensing part; and a leading-end protective layer being a porous layer disposed around an outer periphery of the element base in a predetermined range on a side of the sensing part. The leading-end protective layer includes: a first layer disposed at least on two main surfaces of the element base; a second layer disposed to cover the end portion and four side surfaces of the element base including the two main surfaces; and a third layer disposed to cover the second layer. The second layer has a porosity of 30% to 80%, and has a thickness of 30 to 50 times thickness of the first layer, and the third layer has a porosity of 15% to 30%, and has a thickness of 5 to 10 times the thickness of the first layer.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: May 10, 2022
    Assignee: NGK INSULATORS, LTD.
    Inventors: Takashi Hino, Atsushi Watanabe, Ryo Hayase
  • Patent number: 11327044
    Abstract: An electrochemical sensor (1, 101) has a sensor element (15, 115) with a measuring surface (8, 108) that faces a measuring medium (5) during use. The sensor element has a planar measuring element (2, 102). A sensor shaft (4, 104) has an aperture (13, 113) with a bezel (11, 111) at an end which, during use, faces the measuring medium. The sensor element is installed in the area of the aperture. The electrochemical sensor also has an annular sealing element (9, 109), which is arranged between the sensor element and the bezel. An insulator element (10, 110) is firmly and inseparably connected to the measuring element, exposing or recessing the measuring surface. Thus, the sealing element, which protects the electrochemical sensor against the ingress of measuring medium, is arranged sealingly between the insulator element and the bezel.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: May 10, 2022
    Assignee: Mettler-Toledo GmbH
    Inventors: Andreas Rutz, Juan Limon Petersen
  • Patent number: 11320392
    Abstract: Provided is a heavy metal detecting sensor. The heavy metal detecting sensor includes an electrode and a plurality of amyloid fibers disposed on the electrode, wherein an amount of a redox current of the electrode decreases when the plurality of amyloid fibers react with heavy metal ions.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: May 3, 2022
    Assignee: Korea Universitv Research and Business Foundation, Sejong Campus
    Inventors: Jin Sung Park, Joo Hyung Park, Won Seok Lee, Gyu Do Lee
  • Patent number: 11313829
    Abstract: Provided herein is a wet protein blotting system comprising (a) a dry assembly module; (b) a protein blotting chamber; (c) a liquid transfer buffer handling system; and (d) a control panel and power supply. The wet protein blotting systems provided herein reduces the blotting time of a traditional wet blotting process while maintaining the ability for high sensitivity in the transfer of proteins from a polyacrylamide gel to a membrane. Also provided are dry assembly modules and liquid transfer buffer handling systems that enable a fully automatic buffer manipulation system by one or more than one transfer buffers could be pumped into the protein blotting chamber to enhance the transfer efficiency. Also provided is a protein blotting chamber capable of controlling the temperature of the wet protein blotting system.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: April 26, 2022
    Assignee: Nanjing GenScript Biotech Co., Ltd.
    Inventors: Xin Chen, Chao Wang
  • Patent number: 11313830
    Abstract: An electrophoretic separation device includes an anode and a cathode, a porous scaffold material, and a liquid separation medium, wherein the separation medium is located inside the porous scaffold material, is in contact with the cathode and the anode, and has been applied to the porous scaffold material in form of a custom-made geometrical shape defining a migration path for a biomolecule-containing sample, wherein the sample is enclosed by the separation medium.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: April 26, 2022
    Inventors: Ludwig Gutzweiler, Lutz Riegger
  • Patent number: 11307168
    Abstract: An online calibration system for an electrochemical sensor. The calibration system comprises a calibration electrode coupled with a redox species, where the redox species is configured to control a pH of a reference solution local to the calibration electrode, such that when a voltammetric signal is applied to the calibration electrode the output generated from the calibration system is determined by the local environment pH. The output signal from the calibration system is used to calibrate a reference potential generated by a reference system of the electrochemical sensor to correct for drift in the reference potential when the electrochemical sensor is being used. The calibration electrode may be disposed in a reference cell of the electrochemical sensor.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: April 19, 2022
    Assignee: ANB Sensors Limited
    Inventors: Steven A. Gahlings, Nathan Lawrence
  • Patent number: 11307169
    Abstract: A pH sensor with automatic water storage and replenishment, including a substrate, a working electrode, a reference electrode, a first piezoelectric micropump, a water storage device, and a second piezoelectric micropump. The working electrode, the reference electrode, the first piezoelectric micropump, the water storage device, and the second piezoelectric micropump are arranged on the substrate. The working electrode and the reference electrode are each connected to a bonding pad through an electrode lead. The second piezoelectric micropump, the water storage device, and the first piezoelectric micropump are sequentially communicated, and a liquid flows to the working electrode via an outlet of the first piezoelectric micropump.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: April 19, 2022
    Inventors: Xiliang Zhang, Chengxuan Lu, Cheng Chen, Shengkang Zong, Mengyao Ni
  • Patent number: 11298700
    Abstract: Digital microfluidics apparatuses (e.g., devices and systems) configured to determine provide feedback on the location, rate of movement, rate of evaporation and/or size (or other physical characteristic) of one or more, and preferably more than one, droplet in the gap region of a digital microfluidics (DMF) apparatus.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: April 12, 2022
    Assignee: mirOculus Inc.
    Inventors: Ik Pyo Hong, Irena Barbulovic-Nad, Jorge Abraham Soto-Moreno
  • Patent number: 11293890
    Abstract: Disclosed are multi-enzyme biosensors that are stable at ambient temperature, and methods of making thereof.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: April 5, 2022
    Assignee: Instrumentation Laboratory Company
    Inventors: Xiaoxian Xu, Prasad Pamidi, Jose Cervera
  • Patent number: 11293062
    Abstract: Techniques for measuring sequences of nucleic acids are provided. Time-based measurements (e.g., forming a histogram) particular to a given sequencing cell can be used to generate a tailored model. The model can include probability functions, each corresponding to different states (e.g., different states of a nanopore). Such probability functions can be fit to a histogram of measurements obtained for that cell. The probability functions can be updated over a sequencing run of the nucleic acid so that drifts in physical properties of the sequencing cell can be compensated. A hidden Markov model can use such probability functions as emission probabilities for determining the most likely nucleotide states over time. For sequencing cells involving a polymerase, a 2-state classification between bound and unbound states of the polymerase can be performed. The bound regions can be further analyzed by a second classifier to distinguish between states corresponding to different bound nucleotides.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: April 5, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: John Mannion, Morgan Mager
  • Patent number: 11280721
    Abstract: Methods and equipment for determining conditions of adhesion between a first and a second mechanical element are disclosed. The mechanical elements are attached respectively to a first and second support, which are immersed in an electrolyte together with a counter-electrode and a reference electrode to form an electrochemical cell. The second mechanical element is a working electrode being connected to an insulated electric wire that is also connected to the counter-electrode. A first uncovered face of the second element is pressed against the first element. A potential is applied to the second element of at least one predetermined value and/or a predetermined electrical current. The method can include detecting the electrical current that is transmitted through the electrolyte as a function of the potential applied and/or the potential that is established as a function of the predetermined current.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: March 22, 2022
    Assignee: ITT Italia S.R.L.
    Inventors: Agustin Sin Xicola, Lorenzo Fedrizzi, Francesco Andreatta, Alessandro De Nicolo
  • Patent number: 11278227
    Abstract: Provided is a biometric information measurement method. The method includes providing a bio-material including at least one of cells and tissues, contacting a first electrode and a second electrode with the bio-material and applying a first electrical signal and a second electrical signal to the bio-material, sensing a third electrical signal from the bio-material, and analyzing an oxygen concentration in the bio-material from the third electrical signal.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: March 22, 2022
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Young Sam Park, Jaehyun Moon, Seongdeok Ahn, Byoung Gon Yu, Jeong Ik Lee, Nam Sung Cho, Doo-Hee Cho
  • Patent number: 11280755
    Abstract: An example device includes a processor to connect to an electrode disposed within a microfluidic volume and to connect a second electrode that includes a surface of silver metal disposed within the microfluidic volume. The processor is to apply an electrical potential between the electrode and the second electrode when the microfluidic volume contains a fluid that contains chloride ions to form a layer of silver chloride on the surface of the second electrode. The processor is further to cease application of the electrical potential and operate the second electrode as a reference electrode in a measurement process performed within the microfluidic volume.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: March 22, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Sarah Gish, Tod Woodford, Alexander Govyadinov
  • Patent number: 11275049
    Abstract: A gas sensor includes a structural body made from an oxygen ion conductive solid electrolyte, a gas introduction passage which is formed in the structural body and into which a gas to be measured is introduced, a main adjustment chamber that communicates with the gas introduction passage, and a measurement chamber that communicates with the main adjustment chamber. A buffer space that communicates with the gas introduction passage, and at least two diffusion rate control members that communicate with the buffer space, are provided between the gas introduction passage and the main adjustment chamber. The respective widths Wb1 and Wb2 of the diffusion rate control members are less than the respective widths Wa, Wc, and Wd of the gas introduction passage, the buffer space, and the main adjustment chamber.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: March 15, 2022
    Assignee: NGK INSULATORS, LTD.
    Inventors: Yusuke Watanabe, Mika Kai, Shiho Iwai
  • Patent number: 11274329
    Abstract: Provided herein are plant/plant pathogen volatile compound electrochemical sensors, plant/plant pathogen volatile detection systems, and methods for detecting stress-induced plant volatile compounds and/or a plant-pathogen emitted volatile compounds.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: March 15, 2022
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Ramaraja P. Ramasamy, Yi Fang
  • Patent number: 11266864
    Abstract: A corrosion monitoring device includes a sensor assembly and a detector circuit. The sensor assembly includes at least one sensor portion disposed in an interior of a pipe in a fire sprinkler system for sensing corrosion of a wall of the pipe. The detector circuit transmits an electrical signal through the at least one sensor portion, monitors an electrical characteristic of the at least one sensor portion based on the electrical signal, compares at least one of the monitored electrical characteristic and a change in the electrical characteristic of the at least one sensor portion to at least one of a predetermined value and a previously monitored electrical characteristic, determines a corrosion status indicative of at least one of a corrosion level and a rate of corrosion of the pipe wall based on the comparison, and outputs an indication of the corrosion status.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: March 8, 2022
    Assignee: Tyco Fire Products LP
    Inventors: Jeremy Tyler Cogswell, Arash Agan, Cassandra Lyn DeNunzio
  • Patent number: 11262329
    Abstract: Disclosed herein is a method of testing a corrosion resistance of a coated metal material including a surface treatment film on a metal substrate. The method includes: treatment of interposing a water-containing electrolyte material containing water, a supporting electrolyte, and a water penetration enhancer, between a surface of the surface treatment film of the coated metal material and an electrode; holding of the water-containing electrolyte material on the surface of the surface treatment film for one minute to one day; and electrical conduction from the electrode through the water-containing electrolyte material to the coated metal material.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: March 1, 2022
    Inventors: Teruaki Asada, Tsutomu Shigenaga
  • Patent number: 11255834
    Abstract: Test sensors, methods, and systems are described that include a first electrode pair having either two active electrodes or an inactive working electrode paired with an active counter electrode. These active electrodes are different than having an electron transfer mediator on an inactive electrode because in addition to the structural differences between an electrode directly in contact with the conductors of the test sensor verses a reagent coating, there are chemical and functional differences. The active electrodes are formed from an electrode core material including an element that loses or acquires electrons during the analysis and directly participates in the electrochemical reaction of the sample. As the active electrodes are insoluble in the sample during the analysis, an electrochemically stable potential is provided by the active electrodes that can reliably operate at higher operating potentials than conventional electron transfer mediator reagents coated on an inactive electrode.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: February 22, 2022
    Assignee: Conductive Technologies, Inc.
    Inventors: Matthew K. Musho, Christina A. Beaverson, Nicholas F. Szabo
  • Patent number: 11255811
    Abstract: A sensor for the detection of lead includes a substrate, a working electrode formed on a surface of the substrate, a counter electrode formed on the surface of the substrate, a dielectric layer covering a portion of the working electrode and counter electrode and defining an aperture exposing other portions of the working electrode and counter electrode. The working electrode includes a metalized film with working surface and a monolayer (or bilayer) of bismuth deposited on the working surface by underpotential deposition.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: February 22, 2022
    Inventors: Chung Chiun Liu, Yifan Dai
  • Patent number: 11255805
    Abstract: Sensors having an advantageous design and methods for fabricating such sensors are generally provided. Some sensors described herein comprise pairs of electrodes having radial symmetry, pairs of nested electrodes, and/or nanowires. Some embodiments relate to fabricating electrodes by methods in which nanowires are deposited from a fluid contacted with a substrate in a manner such that it evaporates and is replenished.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: February 22, 2022
    Assignee: NanoDX, Inc.
    Inventors: Farhad Khosravi, David Bastable, Sergey A. Dryga