Patents Examined by Amy C Bonaparte
  • Patent number: 11078221
    Abstract: Compounds of general formula (I): (Formula I)) wherein R1, Q, R3, R4, R5, R6, R7 and Ar1 are as defined herein are inhibitors of class I histone deacetylases and are of use in the treatment of lysosomal storage disorders, especially Niemann-Pick type C disease, as well as other lysosomal storage disorders, defective autophagy, accumulation of free cholesterol and mycobacterial diseases.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: August 3, 2021
    Assignee: UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD
    Inventors: Emyr Lloyd-Evans, Fabrizio Pertusati, Edward James, Emily Maguire, Christopher McGuigan
  • Patent number: 11078149
    Abstract: Processes for separating a di-carboxylic acid or salt thereof from a mixture containing the di-carboxylic acid or salt thereof and one or more other components are provided. Also separation media useful for these separation processes is provided. In particular, processes for preparing an aldaric acid are described, such as glucaric acid from glucose, which includes separating the aldaric acid from the reaction product. Also, various glucaric acid products are described.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: August 3, 2021
    Assignee: Archer-Daniels-Midland Company
    Inventors: Gary M. Diamond, Eric L. Dias, Raymond Archer, Vincent J. Murphy, Thomas R. Boussie
  • Patent number: 11072621
    Abstract: The present disclosure relates to a preparation method of a methionine-metal chelate, and the methionine-metal chelate, which is prepared by first reacting Ca(OH)2 and methionine and adding metal chloride salts, can be used as feeds and feed additives.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: July 27, 2021
    Assignee: GJ CHEILJEDANG CORPORATION
    Inventors: Jun-Woo Kim, Min Kyu Kang, Gyeonghwan Kim, Il Chul Kim, Juun Park, Yong Bum Seo, In Sung Lee, Jun Young Jung, Je-won Hong
  • Patent number: 11072578
    Abstract: Provided are aromatic oligoamide foldamers and self-assembled compositions of the same. The aromatic oligoamide foldamers and compositions can form tube-like structures that can form pores in membranes. The pores can be used to transport ions and molecules, such as, for example, cryoprotective agents or therapeutic agents, through the membrane. The tube-like structures exhibit desirable stability at low temperatures.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: July 27, 2021
    Assignee: The Research Foundation for The State University of New York
    Inventor: Bing Gong
  • Patent number: 11066434
    Abstract: This invention relates generally to olefin metathesis catalysts comprising aniline type ligands, to the preparation of such catalysts, compositions comprising such catalysts, methods of using such catalysts, and the use of such catalysts in the metathesis of olefins. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and in industrial applications such as oil and gas, fine chemicals and pharmaceuticals.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: July 20, 2021
    Inventors: Adam M. Johns, Richard L. Pederson, Doina Ene, Ralf Karch, Angelino Doppiu
  • Patent number: 11059774
    Abstract: The present disclosure relates to fluid bed processes that utilize silica particles as a fluidization aid. The process comprises reacting one or more reactants in a reactor comprising a fluid bed to form a product. The fluid bed comprises a catalyst composition comprising a catalyst and an inert additive composition comprising silica particles from 0.5 wt % to 30 wt %, based on the total weight of the catalyst composition. The silica particles are discrete, inert particles that are mixed with the catalyst in the fluid bed.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: July 13, 2021
    Assignee: Ascend Performance Materials Operations LLC
    Inventors: Yawu T. Chi, James Sutton, Ali Akhavan, Celia L. Kniepmann, Matthew D. Cox, Valerie S. Monical
  • Patent number: 11059021
    Abstract: The invention relates to a process for the preparation of one or more intermediate chemical compounds useful in the preparation of non-ionic contrast agents wherein the process is carried out continuously using one or more flow procedures.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: July 13, 2021
    Assignee: Hovione Scientia Limited
    Inventors: William Heggie, John Naber, Patrick R. Bazinet, Filipe Tomas
  • Patent number: 11053188
    Abstract: The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting to a cyclobutanone, or (d?) further reacting to an enamide, (c) further reacting to enantiomerically and diastereomerically enriched cyclobutane amines, or (d) further reacting to an enamide and (e) to an enantiomerically and diastereomerically enriched cyclobutylamide to obtain (f) an enantiomerically and diastereomerically enriched cyclobutane amine, and (g) further reacting to an enantiomerically and diastereomerically enriched cyclobutane amide.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: July 6, 2021
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Raphael Dumeunier, Tomas Smejkal, Brijnandan Premnath Mishra, Vijayagopal Raman Gopalsamuthiram, Edouard Godineau, Anthony Cornelius O'Sullivan
  • Patent number: 11040940
    Abstract: The subject of the present invention is a weakly corrosive and weakly coloured sulfonic acid, with an APHA colour index of less than 20, comprising chlorides and nitrites in a chloride/sulfonic acid molar ratio of between 1 ppm and 200 ppm, and a nitrite/sulfonic acid molar ratio of between 200 ppm and 6000 ppm, limits inclusive.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: June 22, 2021
    Assignee: ARKEMA FRANCE
    Inventors: Jean-Alex Laffitte, Bernard Monguillon
  • Patent number: 11040933
    Abstract: Disclosed is a preparation method of phenoxycarboxylic acid herbicides. The preparation method comprises the following steps. S1: mixing an anhydrous phenol and a basic substance with a chloro-substituted carboxylic acid ester and performing a one-pot condensation reaction in an anhydrous system to obtain a phenoxycarboxylic acid ester. The chloro-substituted carboxylic acid ester is represented by the formula ClR1COOR, in which R1 is a C1-3 alkanediyl or alkylidene group, R is a C1-10 alkyl group or a C3-10 cycloalkyl group; S2: the phenoxycarboxylic acid ester undergoes selective chlorination with a chlorinating agent in the presence of a first catalyst and a second catalyst to obtain a chloro-substituted phenoxycarboxylic acid ester; and S3: the chloro-substituted phenoxycarboxylic acid ester undergoes an acid hydrolysis reaction to obtain a phenoxycarboxylic acid herbicide represented by formula I, in which R3 is H, Cl or CH3.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: June 22, 2021
    Assignee: SHANDONG RAINBOW BIOTECH CO., LTD.
    Inventors: Guoqing Sun, Yongsheng Hou, Liguo Zhang, Zhilong Chi, Yishan Hu
  • Patent number: 11040336
    Abstract: A catalyst including platinum (Pt) and a composite support. The composite support includes ZrO2/mesoporous silica sieve SBA-15. The platinum accounts for 0.01-0.3 wt. % of the catalyst. ZrO2 accounts for 5-20 wt. % of the composite support.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: June 22, 2021
    Assignee: XIANGTAN UNIVERSITY
    Inventors: Jicheng Zhou, Yanji Zhang, Fei Wang
  • Patent number: 11028046
    Abstract: The present invention relates to a toluene diisocyanate purification method enabling acquisition of a product having a small amount of dimers in a final product by means of using a reactive dividing wall column during toluene diisocyanate preparation. More particularly, according to the present invention, in order to obtain a product having a small amount of dimers in accordance with a reversible reaction of a monomer and a dimer, a purification procedure is designed by means of applying the temperature, pressure, time of stay and the like of a reactive dividing wall column as appropriate particular conditions, a reboiler having short time of stay and high heat transfer rate is used, and thus a dimerization reaction is inhibited and the purity and yield of the product are enhanced. Therefore, high-purity toluene diisocyanate can be purified and obtained.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 8, 2021
    Assignee: HANWHA CHEMICAL CORPORATION
    Inventors: Hyun Cheol Ryu, Kee Do Han, Seong Ho Park, Chang Mo Chung
  • Patent number: 11028043
    Abstract: Methods of making N-hydroxyalkylated polyamines are provided, in which the method includes reacting a polyamine comprising Formula (XXIV): with a cyclic oxide to produce the N-hydroxyalkylated polyamine, where R1 and R2 are independently a —C or —CH group; R3 is an aliphatic hydrocarbyl; and R4 and R5 are independently acyclic hydrocarbyls, or are covalently connected to form an unsaturated cyclic hydrocarbyl.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: June 8, 2021
    Assignee: Saudi Arabian Oil Company
    Inventors: Matthew Hilfiger, B. Raghava Reddy
  • Patent number: 11027984
    Abstract: A process for producing urea with controlled excess of CO2 and/or NH3. The process includes the steps of: reforming the hydrocarbon feed gas, thereby obtaining a synthesis gas comprising CH4, CO, CO2, H2 and H2O, shifting the synthesis gas, removing CO2 from the synthesis gas, removing residual H2O and/or CO2 from the synthesis gas, removing CH4, CO, Ar and/or He, and adding stoichiometric nitrogen to produce NH3 to the synthesis gas, synthesizing NH3 to obtain a NH3 product, and adding at least part of the product CO2 and at least part of the NH3 product to a urea synthesis step to make a urea product. The amount of excess CO2 and/or NH3 is controlled by adjusting the steam/carbon in the reforming step and/or the H2O addition upstream the shift step and/or adjusting the inlet temperature to at least one or more shift steps.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: June 8, 2021
    Assignee: Haldor Topsoe A/S
    Inventors: Christian Henrik Speth, Per Juul Dahl, Annette E. Kroll Jensen, Niels Christian Schjødt, Marcus Symreng
  • Patent number: 11021436
    Abstract: Provided is, for example, a compound excellent in light fastness and storage stability. The compound is characterized by having a structure represented by the following formula (1) or (2).
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: June 1, 2021
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Koromo Shirota, Taichi Shintou, Ai Hayakawa, Tsuyoshi Santo
  • Patent number: 11014875
    Abstract: The present disclosure is related to obtaining and using sulfobetaine and hydroxysultaine-based geminal zwitterionic liquids as wettability modifiers for rocks such as limestone, dolomite, sandstone, quartz or heterogeneous lithologies, under the presence of brines having high content of divalent ions as calcium, magnesium, barium and strontium, at high temperature and high pressure conditions for enhanced oil recovery processes to increase the oil production. The geminal zwitterionic liquids of the present disclosure have also the property of acting as corrosion inhibitors of ferrous metals used in pipelines and equipment for crude oil extraction, production, transport and storage operations. A further advantage shown by zwitterionic liquids derived from their molecular structure is they can be dissolved in distilled water, brine, hydrocarbon solvents, aromatics and alcohols.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: May 25, 2021
    Assignee: INSTITUTO MEXICANO DEL PETROLEO
    Inventors: Raül Hernandez Altamirano, Violeta Yasmin Mena Cervantes, Luis Silvestre Zamudio Rivera, César Andrés Flores Sandoval, Alejandro Ramírez Estrada, Rodolfo Cisneros Devora, José Manuel Martínez Magadan, Raúl Oviedo Roa, Jorge Francisco Ramírez Pérez
  • Patent number: 11007199
    Abstract: This invention is directed to compositions, methods and kits that can be used for the treatment or amelioration of pain and fever.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: May 18, 2021
    Assignees: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, University of Alcala De Hernares, South Rampart Pharma, LLC
    Inventors: Nicolas Bazan, Hernan Bazan, Julio Alvarez-Builla Gomez, Dennis Paul, Carolina Burgos Garcia
  • Patent number: 10995002
    Abstract: Existing methods of producing high quality graphene/graphite oxides are generally accomplished by exfoliating graphite into flakes and oxidizing the graphite flakes with strong oxidizers under extreme conditions and require careful purification. The oxidizers are typically strong acids used in high concentrations at elevated temperatures requiring complicated purification processes to yield oxidized graphene/sheets. The existing processes can cost up to $12,000/gram. This invention uses a mild oxidant combined with mechanical processing where the sole products are oxidized graphite/graphene and water without the need for further purification.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: May 4, 2021
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Richard Blair
  • Patent number: 10995077
    Abstract: The present invention relates to a process to prepare ethyleneamines of the formula NH2—(C2H4—NH—)pH wherein p is at least 2 wherein one or more units —NH—C2H4—NH— are present as a piperazine unit or precursors thereof wherein optionally one or more units —NH—C2H4—NH— are present as a cyclic ethylene urea unit or between two units —NH—C2H4—NH— a carbonyl moiety is present, by reacting an ethanolamine-functional compound, an amine-functional compound in the presence of a carbon oxide delivering agent, wherein at least one of the amine-functional compound or the ethanolamine-functional compound contains a piperazine unit, and the reaction is performed in a liquid that comprises water.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: May 4, 2021
    Assignee: NOURYON CHEMICALS INTERNATIONAL B.V.
    Inventors: Rolf Krister Edvinsson, Eike Nicolas Kantzer, Per Fredrik Olmo Larsson, Karl Fredrik Lake, Antoon Jacob Berend Ten Kate, Ina Ehlers
  • Patent number: 10981861
    Abstract: The present disclosure provides a bromination method for m-diamide compounds comprising reacting a compound represented by formula I with a brominating reagent in the presence of an oxidant to obtain a brominated product represented by formula II. The method adopts a special design of brominating reagents and reaction conditions to introduce a bromine atom at a specific site of the m-diamide compound, with 87.9 to 99.5% yield of a brominated product obtained by the reaction and higher than 91.8% purity. Therefore, the bromination method has a simple route, mild reaction conditions, high efficiency, and does not require complicated and cumbersome post-treatment processes; furthermore, raw materials used for the bromination reaction are readily available, costs of the brominating reagent are low, and the brominated product finally obtained has high yield and high purity, thus the method is a novel one with a broad application prospect.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: April 20, 2021
    Assignee: Chang Sha Jia Qiao Biotech CO., LTD.
    Inventors: Jintao Zhu, Liang Lv, Chaoqun Huang, Liangming Luo, Rong Zhang