Patents Examined by Amy L. Clark
  • Patent number: 11766423
    Abstract: Methods for treating one or more diseases associated with neutral sphingomyelinase 2 (nSMase2) in a subject in need of treatment thereof, the method comprising administering to the subject a therapeutically effective amount of 2,6-dimethoxy-4-(5-phenyl-4-thiophen-2-yl-1H-imidazol-2-yl)-phenol (DPTIP) or a pharmaceutically acceptable salt thereof, are disclosed.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: September 26, 2023
    Inventors: Barbara Slusher, Camilo Rojas, Ajit G. Thomas, Norman Haughey, Marc Ferrer, Xin Hu
  • Patent number: 11752182
    Abstract: The present invention is based on a plurality of benefits from the extracts of mycelia of individual fungal species, and mixtures of species, to provide an armamentarium of defenses from multiple stressors in order to help bees survive a complex of symptoms collectively called colony collapse disorder (CCD). More particularly, the present invention utilizes specific concentrations of extracts from pure cultured mycelium from mushroom forming fungi to reduce harmful viruses in bees and to increase the longevity of bees.
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: September 12, 2023
    Inventor: Paul Edward Stamets
  • Patent number: 11723942
    Abstract: Disclosed are powder solid compositions including a hydroalcoholic extract of Bergamot fruit (Citrus aurantium var. bergamia) and at least one phospholipid. Also disclosed is a process for the preparation of the compositions. The compositions are useful for the prevention and/or treatment of dysmetabolic syndromes, dyslipidemias and type 2 diabetes.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: August 15, 2023
    Assignee: INDENA S.P.A.
    Inventors: Massimo Ronchi, Giacomo Mombelli
  • Patent number: 11717552
    Abstract: An extract of an herbal composition comprising at least two different dried plants useful as antimicrobial and/or antibiofilm agent in the treatment or prevention of microbial infections caused by bacteria, such as for example Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Streptococcus or Staphylococcus, or by fungi, such as for example is herein described. It has been found that in such extract, the active ingredients exert their biological effects in a synergistic manner. The extract may constitute the active ingredient of a food supplement, a nutraceutical, pharmaceutical or cosmetic composition or a functional food or a food additive. A process for preparing said extract is also described here.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: August 8, 2023
    Assignee: ALPHANOSOS S.A.S.
    Inventors: Pascal Mayer, Laure Breuils
  • Patent number: 11654120
    Abstract: This disclosure relates to new compositions and methods for treating skin conditions as a result of sun damage. In one embodiment this disclosure pertains to new compositions for treating or preventing sunburns, skin damage, and/or harm from radiation, such as UV radiation.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: May 23, 2023
    Assignee: OLLIE'S HEALTH, LLC
    Inventor: Marshall Ollie Almarode
  • Patent number: 11648233
    Abstract: The present invention is related to an active substance of Hericium erinaceus having a pain-relieving effect, and a pharmaceutical composition including the active substance. The active substance is prepared using the following steps: (a) inoculating a mycelium of H. erinaceus on an agar plate and incubating at 15-32° C. for 8-16 days; (b) inoculating the incubated H. erinaceus mycelia from step (a) into a medium in a flask and incubating at 20-30° C. and pH 4.5-6.5 for 3-5 days; (c) inoculating the incubated H. erinaceus mycelia from step (b) into a medium in a fermentation tank and incubating at 24-32° C. and pH 4.5-5.5 for 8-16 days to obtain a fermented medium of the H. erinaceus mycelia; and (d) desiccating the fermented medium of the H. erinaceus mycelia from step (c) to obtain the powder of the H. erinaceus mycelia, which is further purified and isolated to obtain a novel compound of H. erinaceus.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: May 16, 2023
    Assignee: GRAPE KING BIO LTD.
    Inventors: Pei-Shan Liu, Chien-Chih Chen, Chin-Chu Chen, Li-Ya Lee, Wan-Ping Chen, Ting-Wei Lin, Jui-Hsia Hsu, Wei-Ching Chu
  • Patent number: 11617774
    Abstract: The present invention relates to a composition for preventing and/or treating a stroke or a degenerative brain disease comprising: at least two substances selected from the group consisting of egg yolk lecithin, glycerol, sodium oleate, medium chain triglyceride and refined fish oil; olive oil; and soybean oil. The composition of the present invention has an excellent neuroprotective effect but no toxicity or side effects, and thus can be effectively and safely used for preventing, treating or ameliorating a stroke or a degenerative brain disease.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: April 4, 2023
    Inventors: Jin Gyu Choi, Donghun Lee, Juyeon Park, Jungbin Song, Hocheol Kim
  • Patent number: 11590193
    Abstract: A plant extract obtained from saffron, with a safranal concentration, measured using the HPLC method, of a minimum of 0.2% by weight relative to the total dry matter weight. A method for obtaining the plant extract, as well as compositions comprising the plant extract, and methods of treatment.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: February 28, 2023
    Assignee: ACTIV'INSIDE
    Inventors: David Gaudout, Stephane Rey, Benoit Lemaire, Benjamin Moras, Marion Dumoulin
  • Patent number: 11564943
    Abstract: The invention refers to a decomposed platelet concentrate containing ?50% intact platelets and optionally ?200 pg/ml RANTES and specifically to its use in the prevention or treatment of hair loss and/or for promoting hair growth. The invention further refers to a composition comprising the decomposed platelet concentrate and body fat cells and the use of said composition for reconstructive and aesthetic and curative surgery and pain relief treatment.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: January 31, 2023
    Inventor: Edvin Turkof
  • Patent number: 11547731
    Abstract: Methods of treating inflammation, pain or both inflammation and pain in a subject are provided. The method includes the step of administering a human birth tissue material composition on or within an affected site of a body. The methods are particularly suitable for treatment of inflammation, pain or both inflammation and pain arising from a viral infection.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: January 10, 2023
    Inventor: Timothy R. Brahm
  • Patent number: 11504315
    Abstract: The present invention relates to cosmetic formulations with a high moisturizing power comprising, as active principle, ucuuba (Virola surinamensis) butter comprising myristic acid in high concentration, more particularly in a concentration equal to or greater than 70% of the constitution of said butter. Additionally, the invention relates to products comprising such cosmetic formulations, as well as to the use of ucuuba butter for the preparation of a differentiated cosmetic product with high skin moisturizing power, as will be demonstrated in the present patent application. The invention further discloses a cosmetic kit comprising the formulation disclosed with a suitable applicator and instructions for use.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: November 22, 2022
    Assignee: Natura Cosméticos S.A.
    Inventors: Aurora Maria Domingues Furtado Grafin Von Ysenburg-Philippseich, Simone Emidio, Daniela Veloso Okuta, Debora Cristina Castellani, Mariane Spadoto, Roberta Gisele de Souza Oliveira Pereira, Roberta Roesler, Wagner Franzin Rusca
  • Patent number: 11497785
    Abstract: The present invention relates to a composition for use as an oral anti-parasitic, the composition comprises one or more of an essential oil which contains gamma-terpinene, and/or carvacrol, and/or thymol, and/or terpinenol, and/or eucalyptol and/or eugenol, an essential oil of genus Cinnamomum, Eugenia, Eucalyptus or a source of saponin. It also relates to a method of preventing or treating parasitic infection in an animal, the method comprising orally administering to said animal a composition comprising one or more of an essential oil which contains gamma-terpinene, and/or carvacrol, and/or thymol, and/or terpinenol, and/or eucalyptol and/or eugenol, an essential oil of genus Cinnamomum, Eugenia, Eucalyptus or a source of saponin.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: November 15, 2022
    Inventors: Alexandre Feugier, Nicolas Lerouxel
  • Patent number: 11433020
    Abstract: Formulations such as serums to treat skin discoloration via a multi-modal approach are provided in some embodiments. In several embodiments, the formulations are configured to allow select ingredients to work together to effectively brighten skin and treat hyperpigmentation. In several embodiments, the formulations comprise a first anti-melanin agent, such as a Bidens pilosa extract, a second anti-melanin agent, such as a Rheum rhaponticum extract, and an anti-inflammatory agent, such as a Vitamin E compound. In several embodiments, the formulation is provided as a topical formulation.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: September 6, 2022
    Inventors: Patricia McGill Boland, Deborah Eileen Gregg Bouche, John Anthony Garruto, Bethany Ann McCarver
  • Patent number: 11426438
    Abstract: Synergistic nutraceutical or pharmaceutical anti-inflammatory compositions include a therapeutically effective combination of: an extract selectively enriched in 3-O-acetyl-11-keto-?-boswellic acid (AKBA) derived from Boswellia serrata; and a Boswellia serrata non-acidic resin extract (BNRE). The compositions can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, and/or endothelial dysfunction. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: August 30, 2022
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Patent number: 11389499
    Abstract: The present invention provides methods and compositions for supplementing dietary fiber intake through the administration of new psyllium-containing chocolate food products. The compositions can be used to supplement dietary fiber intake and promote dietary regulation and wellness management. The chocolate composition comprising particular ratios of chocolate, psyllium, and lipids, and the emulsion-forming formulation methods disclosed herein surprisingly reduce the unpleasant gelling in the mouth/throat during mastication/swallowing that is frequently associated with psyllium-containing products. The protective capabilities of the ingredients of the present compositions provide for and, accordingly, allow for, suitable manufacturing and improved organoleptic properties which promote long-term adoption and consistent use by subjects.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 19, 2022
    Inventor: David Phillip Lang
  • Patent number: 11376298
    Abstract: An anti-microbial composition is provided that includes a combination of neem seed oil in an amount of between 10% and 50% and an oil extract of Hypericum perforatum in an amount of between 10% and 50%, wherein the oil extract is obtained from macerated flower crowns of Hypericum perforatum.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: July 5, 2022
    Assignee: KERECIS AG
    Inventors: Fiorella Carnevali, Stephen Andrew Van Der Esch
  • Patent number: 11376294
    Abstract: A method for enhancing at least one of alertness, attention, concentration and memory in a person in need thereof, comprising co-administering an effective amount of mangiferin, norathyriol, or an extract comprising mangiferin or norathyriol; and caffeine to the person. The components may be co-administered in a single composition, or administered in separate compositions. The mangiferin and/or norathyriol exhibit synergistic effects on brain wave activity when co-administered with caffeine.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: July 5, 2022
    Assignee: NEKTIUM PHARMA S.L.
    Inventors: Miguel Jimenez del Rio, Julia C. Wiebe, Laura Lopez-Rios, Tanausu Vega-Morales, Ruben Perez-Machin, Alvaro Sanchez-Rodriquez, Carlos J. Mateos, Nigel Peter Gericke
  • Patent number: 11376291
    Abstract: A process for growing mycelium with cannabis, by designing and filling a spawn bag with medium containing cannabis, water and optional grain, followed by inoculating and maturing mycelium spawn to grow and harvest mushrooms with optional drying thereafter.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: July 5, 2022
    Assignee: BYO Holdings, LLC
    Inventors: Jordan Seth Rubin, Andrew Hines Miller
  • Patent number: 11369651
    Abstract: A method for protecting muscles, comprising administering to a subject in need an effective amount of a FU-LING (Poria cocos) extract, tumulosic acid and/or a pharmaceutical acceptable salt of tumulosic acid. In particular, the method of the present invention is for protecting muscle cells against injury, promoting regeneration and repair of muscle, regulating, treating and/or delaying muscle atrophy (especially caused by aging, diseases, and cachexia), or helping normal muscle contraction, maintaining normal muscle physiology, maintaining normal neuromuscular function, maintaining normal energy metabolism, or enhancing energy level.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: June 28, 2022
    Inventors: Chao-Jih Wang, Han-Peng Kuo, Ai-Ling Yeh
  • Patent number: 11364279
    Abstract: A medicament for use in treating hypertension. The medicament is a glycoprotein, a mixture of polysaccharide and protein, a polypeptide or a protein.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: June 21, 2022
    Inventors: Long Cheng, Baozhen Xu, Qian Cheng