Abstract: A method of isolating at least one sphingolipid portion selected from a sphingoid base portion, a ceramide portion, a glycosphingolipid portion or a phosphosphingolipid portion from Cordyceps, in particular from wild-type Cordyceps, allows for obtaining sphingolipid portions having an increased amount of one of sphingoid bases, ceramides, glycosphingolipids or phosphosphingolipids. The sphingolipid portions isolated contained significant amounts of sphingolipids not reported so far, and possess exceptional immunosuppressive activities. A method of treating a subject suffering from an inflammatory disease like an autoimmune disease or an allergic disease includes administering sphingolipids isolated from Cordyceps, in particular from wild-type Cordyceps. A method of treating a subject suffering from an inflammatory disease includes administering certain sphingolipids to the subject.
Type:
Grant
Filed:
April 18, 2016
Date of Patent:
June 14, 2022
Assignee:
Macau University of Science and Technology
Abstract: A micronutrient dosage unit which comprises two or more micronutrients selected from vitamin A, vitamin B2, vitamin B6, vitamin B9, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K, calcium, magnesium, zinc, boron and chromium in one or more specified ratios.
Abstract: The invention provides a method of isolating one or more compounds present in fruit juice or seed extracts that have anti-microbial activity.
Abstract: A method of treating skin by reducing tumor necrosis factor alpha (TNF-?) activity or matrix metalloproteinase enzyme (MMP-1) activity in a person's skin is disclosed. The method can include topically applying a composition that includes an effective amount of an extract of Brachychiton acerifolius to the person's skin to reduce TNF-? activity or MMP-1 activity in the skin.
Type:
Grant
Filed:
January 9, 2020
Date of Patent:
May 17, 2022
Assignee:
MARY KAY INC.
Inventors:
Tiffany Carle, David Gan, Michelle Hines
Abstract: The invention describes a combination of at least one aromatase inhibitor selected from the group of chemical-synthetic aromatase inhibitors and aromatase inhibition exhibiting extracts of soya beans and rapeseed, respectively, and at least one plant extract that contains one or more active ingredient substance(s) extracted from the plant, which is(are) selected from the group of 5? reductase type I and/or type II inhibitors and androgen receptor blockers, said combination being contained for example in a composition and having special properties for influencing hair growth. Uses of this combination are also described.
Abstract: Disclosed is a composition, which comprises Hordeum vulgare extract as an active ingredient and is effective at promoting longitudinal bone growth.
Type:
Grant
Filed:
November 24, 2014
Date of Patent:
May 10, 2022
Assignee:
UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
Inventors:
Hocheol Kim, Juyeon Park, Sang Woug Park, Ji Young Kim, Donghun Lee
Abstract: Embodiments of the invention include plant stem cell products and treatment methods using the products. In some embodiments, the products may include extracts of plant stem cells, such as apple stem cells, and an aerosolizing device configured to create an aerosol from the plant stem cell products and to deliver the aerosol to the lung via inhalation. Treatment methods include aerosol inhalation of the plant stem cell products.
Type:
Grant
Filed:
July 12, 2019
Date of Patent:
April 26, 2022
Inventors:
Maryam Rahimi, Steven Phillip Gallagher
Abstract: The present invention is directed to a homeopathic complex for use in the treatment of various diseases or disorders, including use as an anti-infective agent and/or in the regeneration of diseased or damaged tissue. Ideally, the anti-infective homeopathic complex of the invention may comprise a homeopathic tincture or dilutions thereof of Hepar sulphuris calcareum or other similar profiled Calcarea or Sulphur salt or acid, Lachesis muta or other remedy with a similar profile, Mercurius Solubilis or similar mercury containing remedy and Silica or other silica containing compounds.
Abstract: A cosmetic skin care product comprising a therapeutically effective amount of a honey extract is described, the honey extract having a phenolic compound to saccharides ratio of at least 5 times greater than the raw honey from which the extract is derived and including a mixture of at least ethanol, water and one or more MMP inhibitory phenolic compounds.
Abstract: Mammalian nutritional supplements comprising individual quantities of turmeric, Peganum harmala, and Arum palaestinum are provided, which promote several aspects of human health, and canine health. Advantageously, the turmeric is present in an amount greater than that of Peganum harmala or Arum palaestinum, and the supplements may contain additional beneficial ingredients, such as ?-sitosterol, vanillin, garlic, and Vitamin C.
Type:
Grant
Filed:
February 20, 2019
Date of Patent:
February 15, 2022
Assignee:
Ankh Life Sciences Limited
Inventors:
Gene H. Zaid, Beth Ann Wolf, Larry D. Crow, Robert Preston Moore, Rachel Elizabeth Ropp
Abstract: Suggested are new extracts of microalgae selected from the group consisting of (i) Monodus sp. (ii) Thalassiosira sp. (iii) Chaetoceros sp. and/or (iv) Chlorococcum sp. obtainable by treating said microalgae with a solvent selected from the group consisting of C1-C4 aliphatic alcohols, ethyl acetate, water or their mixtures, removing the dissolved extracts from the residues and recovering the pure extracts from the solvent. The extracts show excellent properties particularly in modulating the metabolism of human skin and hair follicles.
Type:
Grant
Filed:
April 19, 2018
Date of Patent:
February 15, 2022
Assignee:
Symrise AG
Inventors:
Lorenzo Zanella, Paolo Pertile, Michele Massironi, Marco Massironi, Elisa Caviola
Abstract: Topically administrable compositions and methods are included for treating inflammatory skin disease in mammals. The composition includes a therapeutic amount of antihistamine selected from the group consisting of a non-sedating antihistamine, a physiologically acceptable acid of a non-sedating antihistamine, a salt of a non-sedating antihistamine, an amide of a non-sedating antihistamine, and a combination of two or more of these, and emu oil product selected from the group consisting of emu oil, a biologically active fraction of emu oil, and a combination of these. The composition further includes a therapeutic amount of topical corticosteroid. The combination of non-sedating antihistamine and corticosteroid with emu oil has been found to produce a synergistic effect that is more effective in the treatment of inflammatory skin disease than the compounds used separately.
Abstract: Topically administrable compositions and methods for treating skin conditions in mammals, such as acne, rosacea, keratosis pilaris, photo-aging, and photo-rejuvenation. The composition includes a therapeutic amount of antihistamine selected from the group consisting of a non-sedating antihistamine, a physiologically acceptable acid of a non-sedating antihistamine, a salt of a non-sedating antihistamine, an amide of a non-sedating antihistamine, and a combination of two or more of these, and emu oil product selected from the group consisting of emu oil, a biologically active fraction of emu oil, and a combination of these. The composition further includes a therapeutic amount of topical retinoid. The combination of non-sedating antihistamine and retinoid with emu oil has been found to produce a synergistic effect that is more effective in the treatment of skin conditions than the compound used separately.
Abstract: Disclosed is a method for obtaining a unialgal biomass of cells of small multicellular macroalgae, including: preparing a unialgal sample of cells of multicellular macroalgae from a sample of microalgae taken from the natural environment; culturing the unialgal sample of cells of multicellular macroalgae obtained in step in sea water to which at least one nitrogen source is added, in order to obtain an aqueous suspension of the unialgal biomass of cells of small multicellular macroalgae; a step of harvesting the unialgal biomass of cells of small multicellular macroalgae from the aqueous suspension obtained at the end of step; and a step of producing a powder of the unialgal biomass of cells of small multicellular macroalgae obtained in step. Also disclosed is glycolic extract of the aforementioned biomass, to a method for producing the extract, to the use thereof in cosmetics and pharmaceuticals, and to compositions containing same.
Type:
Grant
Filed:
April 8, 2016
Date of Patent:
January 18, 2022
Assignees:
SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC, BIOTECHMARINE
Abstract: The invention is a cosmetic or dermatological preparation and the use thereof, said preparation comprising a combination of a) glycoprotein 1, b) glycoprotein 2, ginseng extract and d) equisetum extract, to protect the skin against extrinsic skin aging.
Abstract: A topical composition including an extract of Allium species, an extract of Citrus species, an extract of Paullinia species and an extract of Theobroma species is used for improving and/or increasing and/or stimulating and/or promoting and/or inducing the pigmentation of hair and/or hairs.
Abstract: Methods for treatment and compositions are provided for increasing the health of humans, livestock, and companion animals. More particularly, dietary supplements (also referred to as PPA (prebiotic, probiotic, antibodies) compositions) for treating humans, livestock, and companion animals, and methods for making and using them for treatment of various conditions are disclosed.
Type:
Grant
Filed:
June 23, 2017
Date of Patent:
December 14, 2021
Assignee:
IG Biosciences Corporation
Inventors:
Valentino Grant, Dayna J. Campbell, George D. Ranglin
Abstract: A method for stimulating or enhancing the immune system with a composition that includes a Eurycoma longifolia aqueous extract. Also provided is a method for reducing the risk of infectious disease by administering the composition. Further disclosed is a method for treating an individual with a Eurycoma longifolia aqueous extract to increase the number of T-cells, improve Scoring of Immunological Vigor, lower immunological age, reduce fatigue, or alleviate or reduce stress.
Type:
Grant
Filed:
December 15, 2017
Date of Patent:
November 9, 2021
Assignee:
Biotropics Malaysia Berhad
Inventors:
Annie George, Yuuki Kawasaki, Azreena Abas
Abstract: Methods for treating chronic wounds with an amniotic fluid having a therapeutically effective amount of tissue inhibitors of matrix metalloproteinases (TIMPs) are described. The amniotic fluid can be obtained from a female donor during a period of gestation when the concentration of endogenous TIMPs are at or near their maximum level. The methods described herein are particularly useful for promoting wound healing in chronic wounds having elevated protease activity, such as increased amounts or specific activity of matrix metalloproteinases.