Patents Examined by Arlen Soderquist
  • Patent number: 11085938
    Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use components configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. The systems can be configured with features such as individual actuation systems for each measurement module, and firmware for initial and ongoing calibration and error detection.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: August 10, 2021
    Assignee: C A Casyso GmbH
    Inventors: Kevin Bels, Christian Brantl, Johannes Wittmann
  • Patent number: 11078412
    Abstract: The present invention relates to a method of analyzing a polyamine having a plurality of amino groups in the same molecule or a monoamine having an amino group and a phenolic hydroxyl group in the same molecule on the basis of the measurement result of the intensity of excimer fluorescence emitted as a result of the derivatization of the polyamine or the monoamine with a fluorescence derivatization reagent having a pyrene group. The method is characterized in that the fluorescence derivatization reagent comprises 2-chloro-4-methoxy-6-(4-(pyren-1-yl) butoxy)-1, 3, 5-triazine represented by the formula (2).
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: August 3, 2021
    Assignees: Shimadzu Corporation, Shizuoka Prefecture Public University Corporation
    Inventors: Makoto Ogaito, Azusa Uchida, Kenichiro Todoroki, Tatsuki Nakano, Toshimasa Toyo'Oka
  • Patent number: 11055726
    Abstract: A system for tracking fuel in a fuel distribution network is provided. The system includes a plurality of tracking devices disposed at a plurality of fuel transport locations including a supplier fuel storage location, a mobile fuel storage location, a stationary fuel storage location and a vehicle fuel location, wherein each tracking device is configured to read in real time the digital tag by receiving a radiation emission spectrum associated with the fuel identification information as the fuel is transported through the plurality of fuel transfer locations. The digital tag includes information about the fuel.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: July 6, 2021
    Assignee: Kuantag Nanoteknolojiler Gelistirme ve Uretim A.S.
    Inventors: Osman Vedat Akgun, Emre Heves
  • Patent number: 11051443
    Abstract: The present invention discloses methods and devices for a germination profile indicator based on conductivity including: utilizing a target-profile correlation of a target profile of an API from a plant seed to a target germination stage, the target profile includes identifying characteristics of chemical components, and wherein the target germination stage relates to a progress of a seed-germination process of the target profile; utilizing a process-profile correlation of germination-process profiles during the seed-germination process to respective process germination stages, wherein each germination-process profile relates to extracted seed material during the respective process germination stage; comparing characteristics of the target profile to corresponding features in the germination-process profiles; selecting an optimal state of the respective process germination stage to maximize an API quantity; and cross-correlating the optimal state to a conductivity range for the seed in a soak water within a g
    Type: Grant
    Filed: December 25, 2019
    Date of Patent: July 6, 2021
    Assignee: Se-cure Pharmaceuticals Ltd
    Inventor: Ron Gutterman
  • Patent number: 11041855
    Abstract: The disclosure relates to wireless detection of analytes (such as bacteria) labeled by electrically, dielectrically, or magnetically active nanoparticles, for example in quality control monitoring for food supply chain management. The disclosed apparatus includes a detection vessel or vial, a resonant sensor tag, an inductively coupled reader to induce and detect resonance in the sensor tag, and an active nanoparticle for labeling. The disclosed wireless detection apparatus and methods use active nanoparticles for the development of wireless sensor systems which can be designed to be compatible with the existing RFID technology infrastructure. For example, commercial RFID readers (e.g., hand-held) used for tracking and tracing operation can be used with the disclosed apparatus to induce and measure a corresponding resonance frequency.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: June 22, 2021
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Premjeet Chahal, Evangelyn C. Alocilja, Saranraj Karuppuswami, Leann Lerie Matta
  • Patent number: 11035836
    Abstract: Embodiments of methods for producing and testing aqueous gas streams within a self-pressurized flow cell are disclosed. The aqueous gas streams comprise mixtures of aqueous salt precursor and aqueous acid precursor that are mixed in-line and introduced to the self-pressurized flow cell to produce aqueous gases. Once in the self-pressurized flow cell, the precursor mixture formed from the mixed aqueous salt precursor and the aqueous acid precursor may react with the sample. Both the sample and the reacted aqueous solution may be subjected to a variety of real-time tests, such electrochemical tests and in line characterization techniques. These embodiments allow for the concentrations of the aqueous salt precursor and the aqueous acid precursor to be accurately and precisely maintained while allowing for increased safety when handling and testing the various toxic aqueous gas streams produced.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: June 15, 2021
    Assignee: Saudi Arabian Oil Company
    Inventors: Steven C. Hayden, Timothy J. Kucharski, Michele L. Ostraat, Rachael O. Grudt, James P. Mullahoo
  • Patent number: 11035818
    Abstract: A blood glucose meter with a low cost user interface has a color glucose scale that is indexed by indicators programmed according to the user's blood glucose target range through a separating computing device due to the limited meter user interface. The color glucose scale is static and placed adjacent to the indicator such as by being molded into the housing, printed on the housing, or attached to the display. The low cost user interface has a monochrome segmented display with certain segments serving as a plurality of indicators. An indicator scaling module uses the target blood glucose range of the person with diabetes to calculate the blood glucose ranges for each indictor to index the color glucose measurement scale. The indicator scaling module can also assign attributes to the indicator such as flashing. The graphic representation of the user's blood glucose measurement aids in user interpretation.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: June 15, 2021
    Assignee: ROCHE DIABETES CARE, INC.
    Inventor: Mark G. Mears
  • Patent number: 11022619
    Abstract: Devices, systems, and methods for measuring the blood loss of a subject during a medical procedure. Blood and other fluids are received within a container, and a blood measurement device determines the hemoglobin concentration of the fluid within the container. The blood measurement device can also calculate the estimated blood loss of the subject based upon the determined hemoglobin concentration and the volume of the fluid within the container and the patient's hemoglobin.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: June 1, 2021
    Assignee: University of Utah Research Foundation
    Inventors: Annette Macintyre, Lara Brewer, Suzanne Wendelken, Quinn Tate, Soeren Hoehne
  • Patent number: 11016075
    Abstract: Provided here are methods, apparatuses, and systems directed to the determination of geochemical properties of liquid hydrocarbons based on the dielectric properties of components of the liquid hydrocarbons using microwaves. Also disclosed is a method for characterizing a geochemical property of a liquid hydrocarbon by measuring the dielectric responses from a portion of the liquid hydrocarbon at different predetermined temperatures in two or more microwave resonant cavities to electromagnetic waves at select microwave frequencies, and determining a geochemical property of the liquid hydrocarbon in response to measurements of the dielectric responses.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: May 25, 2021
    Inventors: Jose Oliverio Alvarez, David Jacobi
  • Patent number: 11009464
    Abstract: Methods, apparatuses, and computer program products are provided where fluid, such as a blood sample, is entered into a microfluidic channel in a microchip where the microfluidic channel possesses a micro/nanopillar array for sorting molecules by size. When the fluid passes through the micro/nanopillar array it is separated into particles of interest or particles not of interest or both. When particles of interest are lit by a light source via a first waveguide in the microchip connecting the light source to the microfluidic channel, then lighted particles of interest can be detected by an optical detector via a second waveguide in the microchip connecting the optical detector to the microfluidic channel. The information from the optical detector can be analyzed further by connecting the microchip to a mobile computing device with its own processing abilities or abilities via the internet or cloud.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: May 18, 2021
    Assignee: International Business Machines Corporation
    Inventors: Huan Hu, Oki Gunawan, Ning Li, Devendra K. Sadana, Joshua T. Smith, William T. Spratt, Yann Astier
  • Patent number: 10989632
    Abstract: An object of the invention is to improve uniformity of a standard sample used for evaluating a gas flow type analysis system. The invention includes weighing a background into a container; adding a sample solution to the background; drying the sample solution; adding a solvent that can dissolve the sample into the container; and drying the solvent added to the container. The invention is also characterized in that the solvent is an organic solvent, in particular, acetone.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: April 27, 2021
    Assignee: Hitachi, Ltd.
    Inventors: Yasuaki Takada, Shun Kumano, Masuyuki Sugiyama, Hisashi Nagano, Tatsuo Nojiri, Hiroki Mizuno, Yuichiro Hashimoto
  • Patent number: 10976297
    Abstract: A sensitive and selective, in-line method to measure and validate the sulfur content at ppb levels in both the liquid and gas phase of fuel. The method includes etching graphene, for example to form a mesa structure comprising horizontal or vertical lines or an array of multidentate star features; functionalizing the etched graphene and attaching metal oxide nanoparticles to the functionalized graphene to form a device; exposing the device to a fuel in the gas or liquid phase; detecting a change in conductivity when sulfur is present in the fuel; and recovering the device for future use. Also disclosed is the related in-line graphene-based ppb level sulfur detector for fuels.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: April 13, 2021
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Evgeniya H. Lock, F. Keith Perkins, Anthony K. Boyd, Rachael L. Myers-Ward, David Kurt Gaskill, Anindya Nath
  • Patent number: 10948466
    Abstract: An in-line electrolytic reagent concentrator device that circumvents the need for additional pumps and supplies of reagents to support operation of a carbonate or ammonia removal device. The device generates regenerant solutions as strong as, or even stronger, than commercially recommended regenerant solutions. The device may also regenerate eluent solutions so as to reduce the frequency of eluent maintenance and replacement in ion chromatography systems.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: March 16, 2021
    Inventors: Kannan Srinivasan, Mrinal Sengupta, SM Rahmat Ullah
  • Patent number: 10928382
    Abstract: A microfluidic device provides high throughput generation and analysis of defined three-dimensional cell spheroids with controlled geometry, size, and cell composition. The cell spheroids of the invention mimic tumor microenvironments, including pathophysiological gradients, cell composition, and heterogeneity of the tumor mass mimicking the resistance to drug penetration providing more realistic drug response. The device is used to test the effects of antitumor agents.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: February 23, 2021
    Assignee: Northeastern University
    Inventors: Tania Konry, Noa Cohen, Pooja Sabhachandani
  • Patent number: 10914681
    Abstract: A functional material includes a porous metal-organic framework (MOF) including an organic ligand derived from benzenedicarboxylic acid and a metal ion cluster coordination-bonded with the organic ligand, and a luminescent molecule in pores of the MOF.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: February 9, 2021
    Assignees: Samsung Electronics Co., Ltd., OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Ha Jin Kim, In Taek Han, Abhijeet K. Chaudhari, Jin-Chong Tan
  • Patent number: 10914679
    Abstract: The invention relates to a method for determining a scale inhibitor concentration in a sample comprising at least a first scale inhibitor, which is a synthetic organic compound comprising at least one ionised group. The method comprises optionally diluting and/or purifying the sample, and allowing the sample to interact with a reagent comprising a lanthanide(III) ion. The sample is excited at a first excitation wavelength and a sample signal deriving from the lanthanide(III) ion is detected at a signal wavelength by using time-resolved luminescence measurement, and the concentration of the at least first scale inhibitor in the sample is determined by using the detected sample signal.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: February 9, 2021
    Assignee: Kemira Oyj
    Inventors: Vesa Nuutinen, Susanna Toivonen, James Johnstone, Harri Härmä, Paul Mundill
  • Patent number: 10906044
    Abstract: Embodiments of present application are directed to micro fluidic devices and particularly digital micro fluidic devices with improved droplet operations, and methods of improving droplet operations in micro fluidic devices.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: February 2, 2021
    Assignee: ILLUMINA CAMBRIDGE LIMITED
    Inventor: Xavier Von Hatten
  • Patent number: 10901228
    Abstract: A curved beam replicator includes a body having a first surface and a second surface. The second surface defines at least a portion of a cavity. The first surface is configured to cause light entering the body from another medium to be refracted at a first angle such that the light strikes the second surface at a second angle. The second surface is configured to cause a first portion of the light striking the second surface to pass through the second surface and be refracted into a medium in the cavity and to cause a second portion of the light striking the second surface to be reflected toward the first surface at a third angle. The third angle such that the second portion of the light is totally internally reflected by the first surface.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: January 26, 2021
    Assignee: THE BOEING COMPANY
    Inventors: Keith Daniel Humfeld, Morteza Safai
  • Patent number: 10883978
    Abstract: An apparatus for calibrating a flux analyzer comprises a first frame; a second frame; and a permeable membrane. The first frame and the second frame are connected or integrally formed. A method for calibrating a flux analyzer is provided which uses an artificial standard rather than a biological standard.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: January 5, 2021
    Assignee: AGILENT TECHNOLOGIES, INC.
    Inventor: Andrew C. Neilson
  • Patent number: 10875023
    Abstract: An oriented loading system is provided. The oriented loading system includes a substrate, a plurality of wells formed in the substrate, each well having a bottom and sidewalls, a plurality of particles loaded in the wells, wherein the particle comprises a core structure and an inner layer comprising magnetic material partially covering the core structure such that a part of the core structure uncovered by the inner layer is exposed, and a metal layer comprising magnetic material deposited partially in the sidewalls of the wells, wherein the inner layer is attracted by the metal layer such that the exposed core structure is oriented towards the bottom of the well or the inner layer is oriented towards the bottom of the well.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: December 29, 2020
    Assignee: PERSONAL GENOMICS, INC.
    Inventors: Ching-Wei Tsai, Hsin-Yi Hsieh, Yu-Hsuan Peng, Wen-Yih Chen, Chun-Jen Huang