Abstract: A system, module and method for continuous countercurrent spiral chromatography are disclosed. The module includes an input port for receiving an input solution, a first mixer for mixing the input solution with a recycled solution to produce a first mixed output, a stage I separator for concentrating the first mixed output to produce a stage I solid fraction, a second mixer for mixing the stage I solid fraction from the stage I separator and an optional buffer solution to produce a second mixed output, and a stage II separator for concentrating the second mixed output to produce a stage II solid fraction which exits the module. At least one separator is a spiral separator. The system includes a plurality of modules, and at least one of the plurality of modules includes a spiral separator. The method includes purifying an unpurified solution with the plurality of modules.

Abstract: Microstructure separation filters are provided herein, as well as chromatography and other separation devices. An exemplary filter device includes a microstructure filter has a plurality of layers of alternating sacrificial and/or structural material which have been etched to create inlet channels and outlet channels. Adjacent ones of the inlet channels and the outlet channels are spaced apart from one another by cross channels that filter a fluid from the inlet channels to the outlet channels. The cross channels include filter features formed by etching away of a portion of the layers. The device also includes a housing configured to receive the microstructure filter.

Abstract: A washed platelet having a sufficiently low blood plasma content rate is more securely and efficiently obtained. A tertiary separator (42) includes a main body (58) which has a third chamber (52) and is formed as an accommodating portion (54a) accommodating a centrifuged platelet (104), an inlet (77c) which allows a platelet containing component (100) and a platelet added solution (102) to flow in, and an outlet (78a) which allows blood plasma, the platelet added solution (102), and the platelet (104) to flow out. A bottom portion (first bottom portion (60)) of at least a portion forming the accommodating portion (54a) in a wall portion included in the main body (58) is formed of a soft material.

Abstract: A liquid delivery device includes a pump head having a pump chamber provided in the inside, a plunger whose tip is slidably inserted into the pump chamber, and at least one plunger pump having a drive mechanism that reciprocates the plunger in its axial direction. Then, at least one of the plunger pumps is a pressurizing pump that pressurizes a mobile phase including a compressible fluid sucked into the pump chamber and then discharges the mobile phase from the pump chamber, and at least the pump head of the pressurizing pump includes a cooling part that is connected to an outlet channel from the pump chamber, and allows the pump head to absorb heat of the mobile phase discharged from the pump chamber to cool the mobile phase.

Abstract: A vise for column, for attaching a plug to a column tube of a column for chromatography comprising the column tube and the plug to be attached to one end of the column tube, is provided. The vise comprises a column supporter configured to be able to support a part of the column for chromatography, a main body configured to be connected to the column supporter and extending from the column supporter by a predetermined distance, and a column presser configured to be supported at another end of the main body opposite to one end to which the column supporter is connected, and configured to be movable toward and away from the column supporter, and configured to be able to press the plug against the column tube.

Abstract: The present invention provides a functionalised polymeric chromatography medium, prepared by a process which comprises (i) providing a substrate formed of one or more polymer nanofibres, (ii) grafting one or more neutral polymer chains from the substrate, and (iii) contacting the grafted product with a reagent which functionalises the product of step (ii) as a chromatography medium, wherein step (ii) comprises reacting a plurality of compounds of formula and/or its enantiomers, and/or its derivatives of formula (I) and/or enantiomers and/or diastereomers thereof: with one or more functional groups present on the nanofibre substrate, wherein R1, R2, R3, R4 and R5 may be the same or different, and are chosen from H, halogen, C1-C4 alkyl, or C1-C4 alkoxy provided that at least one of R1, R2, R3, R4 or R5 is not hydrogen.

Abstract: A filter medium includes: a porous substrate; a nanofiber web laminated on both surfaces of the porous substrate, the nanofiber web being formed of accumulated nanofibers made of a polymer material and having a number of fine pores; and a fuse reinforcement material interposed between the nanofiber web and the porous substrate for adhesion with the nanofiber web and the porous substrate integrally. The porous substrate is surrounded by the nanofiber web except for an upper edge of the porous substrate, the upper edge of the porous substrate protrudes with respect to the nanofiber web to form a protruding portion, and the protruding portion is configured to be connected with a discharge hole through which purified water via the porous substrate is discharged.

Abstract: A method is disclosed for synthesizing nanofilters for water treatment. The method includes: dispersing an active binding agent in an organic solvent solution to create a suspension of the active binding agent and the solution of the solvent; dissolving an organic polymer resin and an anionic surfactant in the suspension of the active binding agent and the solvent solution to create a sol gel; and electrospinning the sol gel to form electrospun nanofiber composites with embedded, surface-active nanoparticles.

Abstract: A vise for column, for attaching a plug to a column tube of a column for chromatography comprising the column tube and the plug to be attached to one end of the column tube, is provided. The vise comprises a column supporter configured to be able to support a part of the column for chromatography, a main body configured to be connected to the column supporter and extending from the column supporter by a predetermined distance, and a column presser configured to be supported at another end of the main body opposite to one end to which the column supporter is connected, and configured to be movable toward and away from the column supporter, and configured to be able to press the plug against the column tube.

Abstract: A preparative liquid chromatograph that separates components in a sample in a separating column and captures a plurality of target components in an eluate from the separating column in individual trap columns, includes: a column switching means configured to switch passages to cause the eluate having been eluted from the separating column and passed through a detector to selectively flow into one of the trap columns, a passage switching means disposed in a passage between the detector and the column switching means and configured to switch between a first state in which the eluate flows to the column switching means and a second state in which the eluate is discharged without flowing to the column switching means. For the switching among the trap columns, the passage switching means and the column switching means are controlled to set the passage switching means in the second state (step S17) before performing the switching operation of the column switching means (step S18).

Abstract: A system for isolating a target molecule from a bioprocess fluid includes a single-use disposable separation device having a plurality of perimeter-bonded layers defining one or more mesofluidic channels of the separation device, wherein each layer includes a biocompatible polymer material, wherein the separation device is configured to separate at least a portion of particles from the bioprocess fluid to generate a substantially clarified bioprocess fluid, and a chromatography system fluidically coupled at the outflow of the separation device in a configuration for further processing the clarified bioprocess fluid.

Abstract: Provided are porous polymeric materials, methods of making same, and methods of using same. The porous polymeric materials include crosslinked calixarene moieties. The porous polymeric materials can be added to a sample and absorb/adsorb pollutants present in the sample. The absorbed/adsorbed pollutant can further be isolated from the porous polymeric material. The porous polymeric materials can be recycled.

Abstract: A system and method for advanced oxidation (10) of treated sewage effluent provide additional treatment to treated sewage effluent (TSE) for reuse thereof. The method includes exposing TSE to ozone and hydrogen peroxide to oxidize contaminants; coagulating remaining waste in the TSE; flocculating the coagulated TSE; holding the flocculated treated sewage effluent in a settling tank for sedimentation; removing coarse suspended particles from the flocculated TSE by filtration after sedimentation; and removing fine suspended particles by ultrafiltration of the TSE after removing the coarse suspended particles. The system includes a chemical mixing tank (16); a homogenizing tank (22); an advanced oxidation process system (24); a rapid mixer; a flocculation tank (28); a sedimentation tank (32); a sand filter (34); and at least one ultrafiltration system (38), (36).

Abstract: A method for producing porous particles of a cross-linked polymer, and porous particles that can be produced according to the method are disclosed. The porous particles of a crosslinked hydroxy- or amino-group-containing polymer have a relatively low swelling factor. A composite material contains the porous particles dispersed in a continuous aqueous phase. The porous particles, or the composite material, are used for purifying organic molecules and for bonding metals from solutions. A filter cartridge contains the porous particles of a cross-linked polymer or the composite material.

Abstract: A method includes receiving a water stream from a hydrocarbon production facility, the water stream having a first concentration of a kinetic hydrate inhibitor (KHI); flowing the water stream through a heat exchanger to heat the water stream to a target temperature; mixing the heated water stream with a treatment chemical to form a two-phase mixture, the treatment chemical having an affinity for the KHI; flowing the two-phase mixture into a separator; and physically separating the two-phase mixture into a first phase and a second phase, the first phase including water and having a second concentration of the KHI less than the first concentration, and the second phase including the KHI and the treatment chemical, the density of the second phase being less than the density of the first phase.

Abstract: A method includes receiving a water stream from a hydrocarbon production facility, the water stream having a first concentration of a kinetic hydrate inhibitor (KHI); flowing the water stream through a heat exchanger to heat the water stream to a target temperature; mixing the heated water stream with a treatment chemical to form a two-phase mixture, the treatment chemical having an affinity for the KHI; flowing the two-phase mixture into a separator; and physically separating the two-phase mixture into a first phase and a second phase, the first phase including water and having a second concentration of the KHI less than the first concentration, and the second phase including the KHI and the treatment chemical, the density of the second phase being less than the density of the first phase.

Abstract: The invention provides a purification column that contains an adsorbent and shows excellent adsorptivity. Specifically, this purification column is provided with an adsorbent and a case that contains the adsorbent and has a tubular housing and treatment fluid supply port and discharge port at both ends of the housing. The purification column is characterized in that: a distribution plate is disposed at least on one end face side of the adsorbent; the distribution plate has a plurality of openings that allow communication of the treatment fluid, a support body, and a protrusion extending from the supporting body to the adsorbent side; and at least part of the protrusion is inserted into the adsorbent.

Abstract: A water filtration device is provided including a pressurized gas chamber receiving a pressurized gas; an open flow chamber receiving a colloidal suspension including water and colloidal particles, the open flow chamber having an inlet and an outlet, the colloidal suspension flowing between the inlet and at least one outlet in a flow direction; and a gas permeable membrane separating the gas chamber and the flow chamber, the gas capable of permeating the membrane, the membrane being water impermeable, the gas permeating the membrane in a direction normal to the membrane so as to induce diffusiophoretic motion on at least some of the colloidal particles opposite to or in a direction normal to the membrane; the at least one outlet having a first outlet with water having a higher concentration of the colloidal particles than a second outlet. Other devices and methods are also provided.

Abstract: A system that fills multiple containers includes a filter with an inlet port and multiple outlet ports. The outlet ports are pre-attached to containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines is connected to a respective container interior. All of the respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. The system can produce batches of multiple sterile containers with sterile medicament in the containers.

Abstract: The present invention relates to a process of desalting crudeoil, in particular a process for desalting a crude oil which comprises an ionic liquid, an organic acid and any resulting organic salt.