Abstract: A flow-directing water filtration system provides a flow of water through a cylindrical filter cartridge that is more uniform by inclusion of multiple water-directing ridges that form channels between them between the inner wall of the housing and an outside wall of the water filter cartridge for directing laminar flow of water along the outside wall of the water filter cartridge to improve distribution of water flow through the water filter cartridge along its length. The ridges may be formed on the inner wall of the housing, may have a half-circular profile and may be helical ridges that spiral along the extent of the cartridge and may taper in profile toward the bottom of the cartridge.

Abstract: Disclosed is a device for chromatographic separations comprising: a manifold comprising a manifold body defining an elongate central duct, the central duct comprising a centrally-located closable duct valve providing selective fluid communication between a first portion of the central duct and an opposed second portion of the central duct, a first plurality of connectors, each connector of the first plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; a second plurality of connectors, each connector of the second plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; wherein said manifold body further defines: a first plurality of branch ducts, each branch duct of which extending from the first portion of the central duct to an individual one of the first plurality of connectors, each of the bra

Abstract: The present invention relates to aluminium-doped chelate resins containing iminoacetic acid groups, to a production process for aluminium-doped chelate resins containing iminoacetic acid groups, and to a device comprising at least one layer of at least one aluminium-doped chelate resin containing iminoacetic acid groups, and to the uses of this device and of the chelate resins for removal of fluoride from water.

Abstract: The invention discloses a separation matrix for purification of biomacromolecules, comprising a plurality of particles (1) having a core region (2) and a shell region (3), wherein: a) said shell region is accessible to a target biomacromolecule; b) said core region is less accessible to the target biomacromolecule than the shell region; and c) the core region comprises a grafted polymer comprising residues of at least one polymerizable monomer.

Abstract: Systems and methods are provided for depleting platelets from blood. The system includes a multi-stage blood separation chamber in which blood is separated into red blood cells and platelet-rich plasma. The platelet-rich plasma is conveyed from a first stage of the chamber to a second stage, where it is separated into platelets and platelet-poor plasma. The platelet-poor plasma is conveyed out of the chamber while the platelets are allowed to accumulate in the second stage of the chamber. When a controller of the system has determined that the maximum chamber capacity of platelets has been accumulated in the second stage of the chamber, the platelets are conveyed out of the chamber to a waste container. The cycle of separating blood into its components, accumulating platelets in the chamber, and then flushing the platelets from the chamber is repeated until a target platelet concentration of the blood is achieved.

Abstract: A polyelectrolyte coated fly ash is described with a method of making and a method of using for the adsorption of a contaminant from a solution. The polyelectrolyte coated fly ash may be made by treating the oil fly ash with acid, and then contacting the product with a positive polyelectrolyte to create a first polyelectrolyte layer, and then with a negative polyelectrolyte to create a negative polyelectrolyte layer. The resulting polyelectrolyte coated fly ash quickly adsorbs contaminants from solution, and may be cleaned and reused.

Abstract: The present invention discloses a high-speed counter-current chromatograph unreeled by a gear ring, including an upper disc, a middle disc and a lower disc, wherein an unreeling gear ring coaxial with the middle disc is fixed above the middle disc, the lower disc is driven by a driving shaft to rotate, the unreeling gear ring is fixed, gear teeth of the unreeling gear ring are distributed on the inner ring thereof, multiple groups of gears engaged with the unreeling gear ring are arranged along the circumferential direction of the inner ring of the unreeling gear ring, gears between the adjacent groups are not engaged with each other, each group of gears includes two gears that are engaged with each other, wherein one gear drives a separation column, the other gear drives an unreeling shaft, the separation column is installed on a separation shaft, the upper ends of the unreeling shaft and the separation shaft are connected with the upper disc, and the lower ends are connected with the middle disc; meanwhile,

Abstract: The invention discloses a separation matrix which comprises a plurality of separation ligands, defined by the formula R1-L1-N(R3)-L2-R, immobilized on a support, wherein R1 is a five- or six-membered, substituted or non-substituted ring structure or a hydroxyethyl or hydroxypropyl group; L1 is either a methylene group or a covalent bond; R2 is a five-or six-membered, substituted or non-substituted ring structure; L2 is either a methylene group or a covalent bond; R3 is a methyl group; and wherein if R1 is a hydroxyethyl group and L1 is a covalent bond, R2 is a substituted aromatic ring structure or a substituted or non-substituted aliphatic ring structure.

Abstract: Polymer-filled ceramic apatites and their uses are provided.

Abstract: A socket unit for a capillary connection system, especially for use in HPLC applications, includes a housing with a housing outer surface and a housing inner surface that define a housing axial cavity. The socket unit also includes a socket connecting mechanism adapted to engage with a corresponding plug connecting mechanism of a plug unit to connect the plug unit and the socket unit together, wherein the socket connecting mechanism is adapted for a predetermined number of discrete connection states between the socket unit and the plug unit.

Abstract: Open tubular capillary columns for liquid and ion chromatography, based upon an ionically impermeable polyolefin capillary having a bore with a sulfonate-group- or amine-group-functionalized internal surface. The capillary columns may include a coating of ion exchanging nanoparticles electrostatically bound to the functionalized internal surface. The capillary columns may be made by exposing the interior surface to a sulfonating reagent comprising chlorosulfonic acid (ClSO3H), preferably from 85 wt % to 95 wt % chlorosulfonic acid at a process temperature of 20 to 25° C. The interior surface may be subsequently exposed to an asymmetrical diamine to form a sulfonic mid-linkage to the diamine, i.e., to form a sulfonamide-linked, amine-group-functionalized internal surface. The coating may be provided by subsequently exposing the interior surface to an aqueous suspension of ion exchanging nanoparticles to electrostatically bond the ion exchanging nanoparticles to the functionalized internal surface.

Abstract: Asymmetric articles are described including a porous substrate with two opposing major surfaces and a porous structure extending between the surfaces, and a polymeric coating on one of the major surfaces and extending into the porous structure to a depth of the porous structure. Methods for making an asymmetric composite article are also provided, including providing a porous substrate, treating the porous substrate with a plasma treatment or a corona treatment from one major surface to a depth of the porous structure between the two major surfaces. The method further includes applying a coating solution to the treated porous substrate and drying the coating solution to form a composite asymmetric composite article having a polymeric coating on one major surface and extending into the porous structure to the depth of the treated porous structure.

Abstract: The present invention relates to the isolation and purification of sialylated oligosaccharides from an aqueous medium in which they are produced.

Abstract: Described is a chromatographic column assembly that includes an outer tube comprising a metal, a first conduit disposed within the outer tube, a second conduit disposed within the outer tube, and a first joint located between the first conduit and the second conduit. The outer tube is deformed by a first uniform radial crimp at a longitudinal location along the outer tube that surrounds the first conduit on a first side of the first joint, and a second uniform radial cramp at a longitudinal location along the outer tube that surrounds the second conduit on a second side of the first joint. The first and second uniform radial cramps form a fluid-tight seal between the first conduit and the second conduit and each have a substantially flat base region over which a diameter of the outer tube is reduced for a non-zero longitudinal length.

Abstract: A method of water treatment includes flowing water that includes nitrogen and phosphorus compounds through a sorption media composition within at least one chamber of a water treatment system. The composition comprises iron filings comprising at most 5 volume (vol) % of the composition, sand particles comprising at least 80 vol % of the composition, and clay particles comprising at most 5 vol % of the composition. The iron filings, sand particles, and clay particles are mixed together. During the flowing, the clay particles attract the nitrogen and phosphorus compounds, which become absorbed onto a surface of the iron filings and the clay, resulting in a removal of the nitrogen and phosphorus compounds and the generation of reaction products. Nitrogen and phosphorus are then recovered from the reaction products.

Abstract: The process involves the use of two rotary valves to implement Varicol operation of a simulated moving bed apparatus to separate a product from at least one multicomponent feed. In a particular embodiment, paraxylene is separated from a mixture of C8 aromatic hydrocarbons. The use of the Varicol process further enhances the separation of the desired product and provides flexibility with a simulated moving bed apparatus using dual rotary valves.

Abstract: Compositions for bromide removal include a two-dimensional material impregnated with silver. The silver may be impregnated in the two-dimensional material by contacting the two-dimensional material with silver ions in an aqueous solution, allowing the silver ions to adsorb on the two-dimensional material, and drying the two-dimensional material. Removing bromide from an aqueous composition including bromide may include contacting the aqueous composition with a two-dimensional material impregnated with silver, and allowing the bromide to react with the silver to yield silver bromide.

Abstract: Described is a mobile phase fitting having reduced corrosion and erosion. The fitting includes a coupling body, compression screw, compression member and gasket. The coupling body has a threaded bore at one end, a tapered cavity, a narrow bore and a fluid channel. The compression screw has an axial bore to receive a tube and a threaded outer surface in engagement with the threaded bore of the coupling body. The compression member is disposed in the tapered cavity and has an axial opening to pass the tube and a tapered surface to engage a surface of the tapered cavity. The gasket is disposed in the narrow bore and has one surface in contact with the first internal surface and has a parallel surface to receive an end face of the tube. Mobile phase flows along a path that includes the tube, an opening in the gasket and the fluid channel.

Abstract: To diminish complication and difficulty in attachment and detachment of analytical columns to and from a column oven. The column oven includes, in a column housing part that includes a space for housing the plurality of analytical columns, a column rack that holds the plurality of analytical columns, an inlet switching valve, and an outlet connection portion. At least either the inlet switching valve or the outlet connection portion is formed integrally with the column rack and capable of being attached to and detached from the column housing part together with the column rack.

Abstract: Embodiments of templated polymeric materials capable of binding lysophosphatidic acids (LPAs) are disclosed. Methods of making and using the templated polymeric materials also are disclosed. The disclosed templated polymeric materials are molecularly imprinted polymers that bind LPAs and facilitate the production of lysophosphatidic acid-enriched samples, for instance through extraction of lysophosphatidic acids from biological samples, such as plasma or serum samples.