Abstract: A catheter mounting arrangement including a main housing unit configurable to be fastenable around a catheter that has been inserted into a fluid cavity within a patient. The main housing unit includes a slot that defines a longitudinal opening through which an uninserted section of tubing of the inserted catheter is passable there through. The main housing unit and inserted catheter includes an engagement arrangement so that once the uninserted section of the tubing of the inserted catheter has passed through the slot there is a fixed vertical support of the catheter within the main housing unit so that the uninserted section of tubing of the inserted catheter remains substantially upright and/or substantially free of kinks or bends.

Abstract: A closure assembly for a syringe or other medical administering device includes an outer sleeve having an access opening and a tip cap removably disposed therein. The tip cap includes a flow restrictor structured for removable, flow restricting connection to the syringe. An indicator member is removably connected within the outer sleeve, in interruptive relation to passage of the tip cap through the access opening. A retaining structure is fixedly connected to the flow restrictor and movable therewith relative to the indicator member. The retaining structure and flow restrictor are collectively structured for retaining engagement of the tip cap with the indicator member, as the tip and indicator member are concurrently removed from the outer sleeve and as the tip cap is disconnected from the flow restricting connection with the syringe.

Abstract: Devices and methods for extracting and concentrating therapeutically active factors from mammalian fluids and tissues are described herein.

Abstract: Described is a medicament delivery device comprising a case adapted to hold a container with a medicament and having a needle, a needle sleeve telescopically coupled to the case and having a first extended position relative to the case in which the needle is covered, a retracted position relative to the case in which the needle is exposed, and a second extended position relative to the case in which the needle is covered, a first indicia disposed on the needle sleeve which is visible in the first extended position and the second extended position, and a second indicia disposed on the needle sleeve and not visible in the first extended position and visible the second extended position.

Abstract: A blunt-tipped cannula needle for injection of fluid into a subcutaneous tissue around a vein. The cannula needle includes a tubular side wall having three straight sections, each having a central axis. A second central axis of the central axes is angled away from a first central axis of the central axes at a first preselected angle in a first plane. A third central axis of the central axes is angled away from the second central axis at a combination of a preselected second angle and a preselected third angle, such that the third central axis is effectively angled away from the second central axis both at the second angle in the first plane and at the third angle in a second plane perpendicular to the first plane. A plurality of apertures in a distal end section of the needle that face the second central axis.

Abstract: A medical device includes: an elongated tube having a wall defining a lumen for the elongated tube, wherein the wall of the elongated tube comprises a first opening; and a first actuating element coupled directly or indirectly to the wall of the elongated tube; wherein at least a part of the first actuating element and the first opening of the wall are located at a same longitudinal position with respect to a longitudinal axis of the elongated tube; and wherein the first actuating element is configured to change size to induce stress and/or displacement at the wall of the elongated tube to cause the elongated tube to bend.

Abstract: A securement device 1 for securely attaching tubular articles 2 to surfaces comprising an anchor pad 3 for placing the securement device 1 on the surface, a substantially cylindrical base 4 on the anchor pad 3 and a screw cap 5 rotatably mountable on the base 4 at a screw mounting 6 defined between the base 4 and the screw cap 5 between an article receiving position and an article gripping position in which radial pressure is applied to the article 2 placed in the securement device 1 to securely hold the article 2 without the use of external adhesive fixings and prevent micro-pistoning of the article 2.

Abstract: A method includes protecting an entire length of a needle of a needle-based device protruding from a needle mount or a body of the needle-based device in a first state of disuse thereof based on providing a needle shield encompassing the entire protruding length of the needle, and encompassing the needle shield completely in the first state of disuse with an external cap. The method also includes providing a guide element protruding inward from an end of the external cap farthest away from the needle mount or the body of the needle-based device, internal to the external cap parallel to a length of the external cap and through the needle shield such that, in the state of disuse, the guide element at least partially envelops the needle therewithin to prevent significant lateral movement of the needle and prevents the end of the external cap from touching the needle.

Abstract: An electrohydraulic microjet drug delivery device includes: a discharge body provided with a power supply unit in which electric energy is stored; and a medicinal fluid delivery body detachably attached to the discharge body, the medicinal fluid delivery body including a pressure generation unit configured to store a pressure generation liquid, a medicinal fluid storage unit configured to store a medicinal fluid, an elastic separation membrane installed between the pressure generation unit and the medicinal fluid storage unit and configured to separate the pressure generation liquid and the medicinal fluid, a discharger installed inside the pressure generation unit so as to be submerged in the pressure generation liquid and configured to generate a spark using the electric energy stored in the power supply unit, and a nozzle kept in communication with the medicinal fluid storage unit.

Abstract: A catheter insertion device is provided for positioning and inserting a catheter, particularly a midline catheter into a patient. The insertion device includes an actuator assembly movable with respect to a housing for deploying the catheter over a needle. A step-wise movement of the actuator advances a catheter assembly, including the catheter, in stages over the introducer needle. An indexing finger of the catheter assembly engages the actuator body during distal advancement of the actuator, and deflects as the actuator is moved proximally. The device further includes a lockout device such as a button, collar, slider, or tab, which allows movement of the catheter relative to the needle but prevents advancement of the catheter to the first stage of the step-wise movement.

Abstract: The expandable sheath and methods of use disclosed herein are used to deliver a prosthetic device through a patient's vasculature. The sheath is constructed to be expandable in the circumferential direction, while maintaining sufficient stiffness in the longitudinal direction to withstand pushing and resist kinking. The sheath includes a plurality of curved arms extending outwardly from a longitudinally extending spine. The curved arms move away from the longitudinal axis of the sheath when pushed radially outwardly by a passing prosthetic device, and move back toward the longitudinal axis once the prosthetic device has passed.

Abstract: An injection device for injecting medicament in a patient includes a syringe coupled to a housing and radially retained by a retaining rib. A needle guard is slideably coupled to the housing and spring biased in a distal direction by a return spring. A ram is slideably coupled to the housing and spring biased in the distal direction by a main spring. An initial position is defined by a retaining arm being disposed in the longitudinal path of the ram preventing firing. A released position is defined by the retaining arm being clear from the longitudinal path of the ram allowing the ram to extend distally. A locked position is defined by the retaining arm being disposed in the longitudinal path of the ram and a lock arm of the ram being disposed in the longitudinal path of the needle guard preventing the needle guard from being retracted.

Abstract: A medicament delivery device configured to provide a variable single dose of medicament is disclosed. The medicament delivery device includes a main body and a syringe arranged in the main body, wherein the syringe comprises a medicament. The medicament delivery device further includes a removable cap and a plunger rod operatively arranged to eject the medicament through a delivery member i.e. an injection needle attached to the syringe. Still further, the medicament delivery device includes a tubular member coupled to the plunger rod. The tubular member is configured to rotate during removing of the removable cap, and the rotation releases the plunger rod thereby allowing the plunger rod to travel a predetermined distance so as to prime the medicament delivery device.

Abstract: A medical connector for use in a fluid pathway includes a housing configured to permit fluid flow between a first medical device and a second device or location. The medical connector includes a valve member configured to be positioned at least partially within the housing. The valve member is configured to receive the first medical device. The valve member can be moved into a second state. The connector can be adapted for use with a catheter assembly.

Abstract: A pessary for the prevention of preterm birth, and in particular two pathological conditions of pregnancy known as isthmico-cervical incontinence and cervical shortening, both of which are associated with increased risks for pregnancy loss and/or premature deliveries of babies. The pessary includes a sleeve supported within a ring by an annular member. The sleeve is intended to contact the cervix and maximize the length of the cervix while the annular member and ring contact the vagina. The pessary may be fabricated from a pliable medical-grade silicon, and the pessary may include one or more sensors to measure various patient parameters indicative of a premature cervical contraction.

Abstract: Apparatuses, systems, and methods are provided for securing an intra-osseous device within a safety device to prevent stick injuries and to guide the removal of the intra-osseous device from the bone of a patient. A body of the safety device has a cavity that receives the intra-osseous device, and the cavity guides the removal of the intra-osseous device along a straight line to prevent injury during removal. The intra-osseous device is drawn past a lock feature that secures the intra-osseous device within the body such that a needle of the intra-osseous device is contained within a cavity of the body and cannot injure the patient, staff members, etc.

Abstract: A therapeutic agent delivery system includes a catheter, a vascular occluder, a pressure sensor system, and a pump system. The vascular occluder is provided at a distal end of the catheter. The pressure sensor system is provided to sense pressure at a distal end of a catheter lumen, and provides feedback to the pump system. The pump system is adapted to control a rate of infusion of a therapeutic agent through the catheter lumen based on the pressure sensed by the pressure sensor system. A method includes deploying the vascular occluder in a vessel, and then sensing a pressure in the vessel. The therapeutic agent is infused into the vessel at a flow rate based on the sensed pressure in the vessel.

Abstract: An expression kit (2) for use in a breast pump device (1) for extracting breast milk from a human breast comprises a breast pump body (20) having a first pressure chamber (21), a second pressure chamber (22), and a membrane portion (5) separating the first and the second pressure chamber (21, 22) from each other. The membrane portion (5) is configured to form a barrier between the first and the second pressure chamber (21, 22) for preventing leakage of human breast milk from the second pressure chamber (22) to the first pressure chamber (21), yet to allow for air exchange between the first and the second pressure chamber (21, 22), wherein the membrane portion (5) is hydrophobic and has the shape of a solid sheet being provided with holes (50) which are configured for rendering the sheet permeable to air and impermeable to liquid.

Abstract: A needle shield remover for a medicament delivery device is presented that has a metal tubular body, a proximal part, a distal part, and a substantially circular cross-section, where the tubular body is arranged with a slot extending from a distal end of the body, at least half the length of the body, towards a proximal end, such that at least the distal part of the body may flex radially outwards to exert a radially inwardly directed clamping force on a needle shield accommodated by the body.

Abstract: An aspiration catheter is provided including a proximal section and a distal section extendable through the proximal section. A vacuum transfer tool may be coupled to a proximal end of the proximal section. The vacuum transfer tool may include a proximal transfer tube and a distal transfer tube, each having an aspiration port in communication with a vacuum source. The proximal transfer tube may be removably received within a proximal end of the distal transfer tube. The distal section of the catheter may be inserted into the proximal section through the proximal transfer tube. The proximal transfer tube may maintain a vacuum around a proximal end of the distal section of the catheter such that when the distal section is removed by decoupling the proximal and distal transfer tubes, the vacuum within the distal transfer tube and proximal section of the catheter is maintained, preventing an escape of any clots.