Abstract: The present invention refers to a composition comprising: a) a crosslinked hydrophilic polymer containing amino functional groups, and b) a swelling agent, wherein the crosslinked hydrophilic polymer a) is obtainable by reacting a hydrophilic polymer containing amino functional groups with a crosslinking agent which contains at least two epoxide functional groups. The invention also refers to a method for preparing said composition and uses thereof in medical applications.

Abstract: The present invention relates to a composition for treating keratin fibers, preferably hair, comprising: (a) at least one silicone oil in an amount of 20% by weight or more relative to the total weight of the composition; (b) water; and (c) at least one polyol in an amount of 10% by weight or more relative to the total weight of the composition, wherein the ratio of the amount of the (b) water/the amount of the (c) polyol is 3 or less. The composition according to the present invention can also provide keratin fibers such as hair with improved cosmetic effects such as smoothness (e.g.

Abstract: A dynamic antimicrobial hydrogel based on natural receptor-ligand recognition, and a preparation method and use thereof are provided. A ligand vancomycin and a receptor AA-based material each are first modified with a modification material, and then a photoinitiator is added to prepare a hydrogel material under irradiation of ultraviolet (UV) light. In the hydrogel, a three-dimensional (3D) network structure is formed through crosslinking. After undergoing a fracture under an external pressure, the hydrogel can rapidly heal itself through crosslinking due to a ligand-receptor interaction and a multi-hydrogen-bond interaction, which bio-mimicks a natural ligand-receptor interaction to realize the dynamics of the hydrogel material. The high antiomicrobial activity of vancomycin imparts the functionality of the hydrogel material; and the physiologically-derived monomer improves the biocompatibility and reduces the biological toxicity.

Abstract: Described are high molecular weight glycosaminoglycan (GAG) hydrogel compositions comprising GAGs covalently crosslinked with a carbohydrate crosslinker, and methods of making the high molecular weight GAG hydrogel compositions. Further described are methods of using the high molecular weight glycosaminoglycan (GAG) hydrogel compositions for reparative or plastic surgery, esthetic dermatology, facial contouring, body contouring, and gingival augmentation.

Abstract: The present technology relates to compositions suitable for depositing personal care actives onto keratinous substrates. More particularly, the technology concerns compositions comprising lipophilic materials which are deposited from an ampholytic-anionic delivery system. The compositions exhibit high deposition of the lipophilic material onto keratinous substrates such as the skin, nails, and/or hair upon application thereto. In one aspect, the disclosed technology relates to a personal care deposition composition for depositing a lipophilic material onto a keratinous substrate comprising: a) at least one ampholytic polymer; b) at least one anionic polymer; c) at least one lipophilic material; and d) water, wherein the weight ratio of the at least one ampholytic polymer to the at least one anionic polymer ranges from about 10:1 to about 1:1.

Abstract: The present invention relates to: an amorphous of spherical embolisation hydrogel having a degradation time that can be precisely controlled in blood vessels; and a preparation method therefor.

Abstract: The present invention relates to the field of perfumery. More particularly, it concerns a consumer product comprising at least one compound of formula (I) and, optionally, a personal care active base. Moreover, the present invention relates to a method of imparting a long-lasting odor, in particular green odor, to surfaces, such as skin or hair.

Abstract: Provided are compositions and methods for reducing pre-existing antibodies against viral vector or gene-editing related proteins. The compositions showed reduction in various antibody titers by administration of a liposome composition complexed with a protein or fragment thereof of a viral vector. The liposomes comprise phosphatidylcholine and phosphatidylserine, wherein some or all of the PS is present as lyso-PS. The compositions and methods can be used in conjunction with gene therapy and nucleic acid based vector based vaccinations and therapeutics.

Abstract: A film-forming composition for skin, including components (A) and (B): (A) a silicone-based film-forming agent; and (B) a fiber having an average fiber diameter of 0.1 ?m or more and 7 ?m or less in an amount of 0.05 mass % or more and 2 mass % or less relative to the whole film-forming composition. A mass ratio of the component (B) to the component (A), (B/A), is 0.05 or more and 1 or less.

Abstract: The present invention relates to oral films containing an active pharmaceutical ingredient (API) capable of providing seizure relief and one or more film-forming polymers, the use of such films, for example for the acute treatment of ongoing seizures, and methods for preparing such films. The film according to the invention is characterized by a rapid dissolution in the buccal cavity followed by a rapid and high systemic absorption.

Abstract: The present invention relates to the use of native and/or porous starch as white pigment in dental health products and in particular in toothpastes. The present invention also relates to the process of fabricating a dental health product composition and in particular a toothpaste composition.

Abstract: The use of nanometric liposome-like (chitosomes) in pharmaceutical or cosmetic composition and a preparation thereof with the chitosomes including chitosan molecules, phospholipid molecules, a cross-linking agent and at least one active pharmaceutical or cosmetic ingredient.

Abstract: The present invention relates to conditioning cosmetic compositions comprising, in a cosmetically acceptable aqueous medium, non-ionic surfactants and cationic polymers. In particular, these compositions are reserved for applications to hair with or without rinsing. In addition, the compositions concern methods of repair, protection, and improvement of hair properties. Additionally, the present invention relates to cosmetic products comprising such cosmetic compositions, such as shampoos, conditioners and hair treatment products, as well as the use thereof.

Abstract: The present invention refers to a dry composition for chemical and physical sun protection, the composition comprising at least one mineral material selected from the group consisting of surface reacted calcium carbonate and/or hydromagnesite, and from 0.1 wt.-% to 100 wt.-%, based on the dry weight of the at least one mineral material of at least one lignin. Furthermore, the present invention refers to an emulsion comprising the inventive dry composition as well as the use of the inventive emulsion for chemical and physical sun protection in a cosmetic formulation.

Abstract: The present invention provides new storable and stable disinfectant compositions comprising use of a solid precursor of an oxidized state of chlorine. The component in the device is devoid of stability issues, since the solid precursors are instantly to be dissolved in water or a pharmaceutically acceptable diluent, adjuvant, or carrier, and combined with an activator, e.g. adipic or succinic acid or their salts, optionally combined with a viscosity enhancer, optionally combined with a dye. The main product according to the invention is generated by dissolving effervescent material in the form of tablets or granules, the resulting solutions from dissolution of the effervescent material are useful disinfectants for treating a broad spectrum of pathogenic bacterial and/or viral, fungal, or parasitic pathogens, denoted microbials.

Abstract: An encapsulated bacteriophage formulation and a method for encapsulating bacteriophages and bacteriophage-related products in polymeric microcapsules is provided. Some embodiments of the method of producing the encapsulated bacteriophages involves a water-in-oil-in-water double emulsion.

Abstract: The present invention relates to a photoprotective composition comprising, in a physiologically acceptable medium, at least one photoprotective compound and a surfactant comprising at least one ester derivative or amide derivative of glycine betaine. It also relates to the cosmetic use of this photoprotective composition for protecting the skin against certain effects of UVA radiation, and also to this photoprotective composition for use thereof in the protection of the skin against erythema caused by UVB radiation. Finally, it relates to the use of the abovementioned surfactant for increasing the sand resistance of a photoprotective composition.

Abstract: Disclosed herein are synthetic nanoparticles, pharmaceutical compositions, kits, or methods for treating and/or preventing cancer. In some embodiments, the synthetic nanoparticles and/or pharmaceutical compositions comprises a pH sensitive liposome, an apolipoprotein, and andrographolide or derivative thereof. In some embodiments, the synthetic nanoparticles are delivered to a subject for treatment of cancer. In some embodiments, the cancer is T-cell lymphoma or B-cell lymphoma.

Abstract: Disclosed herein is a non-flowable and deformable hemostatic compositions comprised of a xerogel crosslinked powdered polysaccharide dispersed within a substantially anhydrous blend of: glycerol, and polyethylene glycol (PEG), wherein the PEG and glycerol are present in a ratio ranging from higher than 1:1.3: to below 1:2.7 by weight, respectively, and wherein the powder content in the composition is above 50%, by weight. Methods of making the non-flowable compositions, and uses of the compositions in methods for treating a wound or a bleeding tissue, such as bone tissue, are further disclosed.

Abstract: A sunscreen composition includes a sunscreen active, a carrier, and a film former polymer. The sunscreen active may be selected from organic sunscreen actives. The carrier may include an amphiphile monolayer to encapsulate a least a portion of the total amount of the sunscreen active. The film former polymer may include an acrylic film former polymer selected from C1-C30 alkyl (meth)acrylates copolymer. Notably, the sunscreen active may provide enhanced photoprotection at relatively low concentration levels when present with the carrier, including the amphiphile monolayer, and the acrylic film former polymer.