Abstract: Some embodiments include a system with a sensor with electrodes including an active electrode and a receiving electrode that is in physical contact with skin of a patient forming an electrical circuit with control electronics of a controller that can measure an electrical parameter using an active electrode and a receiving electrode within a closed loop electrical muscle stimulation system. A sense electrical pulse can be applied to the tissue using the sensor, an electrical parameter measured from the tissue, and a stimulation pulse applied to the tissue based at least in part on the measured electrical parameter. The stimulation is adjustably controlled by the controller to maintain a constant power output to the tissue based on the electrical parameter. A good is coupled to a computer readable medium configured to store usage data, the usage data relating to the patient's use of the good.

Abstract: An electrical treatment apparatus includes an electrode contactable with a body part, a voltage regulator to regulate a voltage applied to the electrode to provide electrical stimulation to the body part, and a control circuit to control the electrical treatment apparatus. While the control circuit is performing the treatment mode in which the voltage regulator is controlled to apply a voltage at a first voltage value corresponding to the treatment mode to the electrode, the control circuit controls the voltage regulator to switch a value of the voltage applied to the electrode from the first voltage value to a second voltage value and to thereafter switch the voltage value from the second voltage value to the first voltage value.

Abstract: The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

Abstract: Disclosed are a needle tip mounted in a cartridge form (in a replaceable manner) to a hand piece of the skin treatment apparatus and allowing a drug to be injected deeply into an invaded potion, and a skin treatment apparatus having the needle tip mounted thereon. The needle tip includes a casing hollow in a vertical direction; a needle unit disposed in the casing and reciprocating in the vertical direction; and at least one sealing member disposed between the casing and the needle unit, wherein the needle unit includes: a housing disposed inside the casing; and at least one needle electrode disposed in the housing of the needle unit and extending in the vertical direction, wherein the at least one sealing member closes a space between the casing and the housing of the needle unit in the vertical direction.

Abstract: The present disclosure provides systems and methods for detecting cardiac activation times of a patient. A system includes a data acquisition system and a processor communicatively coupled thereto. The data acquisition system is configured to detect a plurality of electrograms generated at a plurality of respective electrodes coupled to the patient. The processor is configured to receive the plurality of electrograms from the data acquisition system. The processor is further configured to compute respective energies of the plurality of electrograms. The processor is further configured to detect a cardiac activation time for a first electrogram among the plurality of electrograms based on the respective energy of the first electrogram and the respective energy of a second electrogram that neighbors the first electrogram.

Abstract: A method for positioning an intravascular catheter may include inserting the intravascular catheter into a venous system of a patient, wherein the catheter includes a plurality of electrodes, and multiple electrodes of the plurality of electrodes are configured to emit electrical signals; positioning a distal portion of the catheter in a first position; using one or more electrodes of the plurality of electrodes to acquire an ECG signal; based on the acquired ECG signal, adjusting the distal portion of the catheter to a second position different from the first position; identifying at least one first electrode of the plurality of electrodes to stimulate a first nerve; identifying at least one second electrode of the plurality of electrodes to stimulate a second nerve; and stimulating at least one of the first and second nerves to cause a contraction of a respiratory muscle.

Abstract: The device (1) for the treatment of joint instability and dyskinesia comprises: an inertial sensor (11, 12) for detecting the movements of a limb (2) of a person, adapted to produce movement signals; an electrostimulation element (14) that can be positioned at a predetermined point of the patient's body so as to electrically stimulate muscles involved in the movement of the limb (2); a waveform generator (15) for supplying the electrostimulation element (14); and a processing means (4) connected to the inertial sensor (11, 12) and to the generator (15), comprising: a position module (41) configured to determine positions of the limb (2) on the basis of the movement signals; and a stimulation module (42) configured to produce stimulation signals adapted to control the operation of the generator (15), on the basis of one or more positions of the limb (2) determined by the position module (41).

Abstract: There is provided a method for measuring heart activity of a person in a single-use electrode patch, the method comprising: measuring the heart activity of the person; displaying the heart activity of the person on the basis of the measuring the heart activity; and broadcasting at least one message enabling transfer of heart activity data indicating the heart activity of the person from the electrode patch to the one or more external devices, wherein the broadcasting is performed while the heart activity of the person is being measured and displayed by the electrode patch.

Abstract: A method of measuring bioelectric signals of a patient having an axis extending from the patient's head to the patient's feet includes attaching a patch to the patient's skin. The patch may include a first electrode and a second electrode spaced apart along a longitudinal axis of the patch. The patch may be attached such that the longitudinal axis of the patch is generally aligned with the axis of the patient. The method may also include attaching a third electrode to the patient's skin, and measuring bioelectric signals of the patient using the first electrode, the second electrode, and the third electrode.

Abstract: A bio-signal acquiring apparatus includes a sensor part and a signal processor. The sensor part includes a bio-signal sensor, a load sensor, and an ultrasonic sensor array, the bio-signal sensor configured to detect a bio-signal of an object that comes into contact with the sensor part, the load sensor configured to detect a contact load of the object, and the ultrasonic sensor array configured to detect contact load distribution of the object. The signal processor is configured to obtain a contact load of the object at a region of interest based on the contact load and the contact load distribution, and configured to output the contact load of the object at the region of interest and the bio-signal.

Abstract: A method for identifying changes in an epilepsy patient's disease state, comprising: receiving at least one body data stream; determining at least one body index from the at least one body data stream; detecting a plurality of seizure events from the at least one body index; determining at least one seizure metric value for each seizure event; performing a first classification analysis of the plurality of seizure events from the at least one seizure metric value; detecting at least one additional seizure event from the at least one determined index; determining at least one seizure metric value for each additional seizure event, performing a second classification analysis of the plurality of seizure events and the at least one additional seizure event based upon the at least one seizure metric value; comparing the results of the first classification analysis and the second classification analysis; and performing a further action.

Abstract: A method of monitoring cardiac activity of a user is provided. Heart beat time data is detected by a PPG sensor (110) in a health sensor (100) worn by the user (1). Motion data is detected by a motion sensor (120) in the health sensor (100). The output data of the PPG sensor (110), which comprises heart beat time data, is analyzed to detect arrhythmia periods. The detected heart beat time data, the detected motion data and the detected arrhythmia are forwarded to an external device, where the data can be stored. The output data of the PPG sensor (110) comprising the heart beat time data, the detected motion data and the detected arrhythmia periods are displayed such that a medical professional (2) can analyze this data to determine whether a suspected arrhythmia period is valid.

Abstract: In one aspect, methods of treating a wound are described herein. A method described herein, in some embodiments, comprises treating a wound, such as a chronic wound, by performing a full field laser ablation in a wound bed of the wound and subsequently performing a fractional laser ablation in the wound bed. Additionally, in some cases, the fractional laser ablation step is carried out at substantially the same time as, or immediately following, the full field laser ablation step. In addition, in some instances, a method described herein further comprises performing debridement in the wound bed prior to performing the full field laser ablation in the wound bed.

Abstract: The instant disclosure relates to electrophysiology catheters for tissue ablation within a cardiac muscle. In particular, the instant disclosure relates to an electrophysiology catheter that conforms to a shape of a pulmonary vein receiving ablation therapy for a cardiac arrhythmia and produces a consistent tissue ablation line along a length and circumference of the pulmonary venous tissue.

Abstract: An implantable medical system for intra-body communication, comprising an implantable first device. The first device comprises a plurality of capacitors and a DC blocking capacitor. The first device is configured to discharge the plurality of capacitors via the DC blocking capacitor in an encoded sequence to generate a signal.

Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.

Abstract: A prosthetic aortic valve is configured to be delivered to a native aortic valve of a patient in a constrained delivery configuration within a delivery sheath. The prosthetic aortic valve includes a frame; a plurality of prosthetic leaflets coupled to the frame; a cathode and an anode, which are mechanically coupled to the frame; and a prosthetic-valve coil, which is coupled to the frame and is in non-wireless electrical communication with the cathode and the anode. When the prosthetic aortic valve is in an expanded fully-deployed configuration upon release from the delivery sheath, (a) a line defined between upstream-most and downstream-most points of mechanical coupling between the prosthetic-valve coil and the frame and (b) a central longitudinal axis defined by the frame form an angle of between 20 and 70 degrees. Other embodiments are also described.

Abstract: One aspect is a manufacturing method including providing at least a first electrically conductive wire with an electrical insulation and a second electrically conductive wire with an electrical insulation, providing a first and a second ring electrode surrounding the wires, electrically connecting the first ring electrode with the first wire and the second ring electrode with the second wire, bundling the ring electrodes and the wires by means of a first sheath surrounding the ring electrodes and the wires to obtain a first ring electrode component, providing a second ring electrode component, bundling the ring electrode components by means of a second sheath surrounding the ring electrode components, and partially removing the first and the second sheaths from the ring electrodes to expose ring electrode portions.

Abstract: The present invention is directed to a wearable system wherein elements of the system, including various sensors adapted to detect biometric and other data and/or to deliver drugs, are positioned proximal to, on the ear or in the ear canal of a person. In embodiments of the invention, elements of the system are positioned on the ear or in the ear canal for extended periods of time. For example, an element of the system may be positioned on the tympanic membrane of a user and left there overnight, for multiple days, months, or years. Because of the position and longevity of the system elements in the ear canal, the present invention has many advantages over prior wearable biometric and drug delivery devices.

Abstract: A system and method are presented that electrically stimulates the phrenic nerve whereby said stimulation results in muscle activation of the diaphragm as observed by a measurement of work or power of breathing associated with the inspiratory portion of a stimulated breath.