Abstract: A probe of a target identification system can be extended via a first lumen of a viewing instrument, such as for illuminating an area beyond a distal end of the viewing instrument via an optical path of the viewing instrument. An optical response to the illumination of the area can be received via an optical path of the probe and can be split from other optical signals of the optical path. The optical response information can be used to identify characteristics of a target and to adjust parameters of a working instrument such as a working instrument contemporaneously using the probe.

Abstract: A pulse generating device for delivery of electrical pulses to a desired tissue and configured to be connected to needle electrodes arranged at the desired tissue. The device comprises a determining module configured to determine a primary voltage amplitude of a first pulse and a number of consecutive pulses to be generated. Further, the device comprises a pulse generator configured to generate one or more of the determined number of consecutive pulses such that the generated first pulse has the primary voltage amplitude and that the generated consecutive pulses have a respective voltage amplitude consecutively decreasing between consecutive pulses, whereby an increase in a current value of the generated consecutive pulses above a threshold value is avoided. Furthermore, the device comprises a terminating module configured to terminate generation of the one or more pulses when a value of a total absorbed energy exceeds a threshold value.

Abstract: Dermatological systems and methods for providing picosecond laser pulses at a plurality of treatment wavelengths, wherein at least one of the wavelengths is provided by an optical parametric oscillator (OPO) capable of providing picosecond laser pulses at a wavelength for treating one or more target tissue types such as a sebaceous gland, sebum, or collagen. In some embodiments, multiple OPOs may be provided to enable a wide range of selectable treatment wavelengths.

Abstract: Modulated light therapy devices for treatment of dermatological disorders of the scalp are provided. An exemplary device includes a flexible printed circuit board (FPCB) supporting at least one light emitting device having an emitter height. The FPCB includes multiple interconnected panels and bending regions defined in and between at least some of the interconnected panels as to allow the FPCB to be configured in a concave shape to cover at least a portion of a cranial vertex of the patient. At least one light-transmissive layer proximate to the FPCB is configured to transmit (e.g., incoherent) light emissions generated by at least one light emitting device. At least one standoff is configured to be arranged between the FPCB and the scalp of the patient, wherein the at least one standoff includes a standoff height that exceeds the emitter height.

Abstract: A treatment tool includes an elongated shaft that has a bending mechanism at a distal end thereof; a bending operation part that is connected to a proximal-end side of the shaft in order to operate the bending mechanism; a connection sleeve that is provided at a connection section of the bending operation part where the bending operation part and the shaft are connected, and that rotatably holds the shaft; a rotation operation member that is provided at the proximal-end side of the shaft and that rotates the shaft; and a stopper member that can be made to slide outside the connection sleeve along a direction of a longitudinal axis of the shaft and that is engaged with both the rotation operation member and the connection sleeve at a specific position in a range of movement thereof, thereby locking rotation of the shaft with respect to the connection sleeve.

Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis.

Abstract: Dermatological systems and methods for providing a picosecond laser treatment a plurality of treatment wavelengths, at least one of which is provide by an optical parametric oscillator (OPO) capable of providing picosecond laser pulses at a wavelength in the red region of the visible electromagnetic spectrum for treating one or more target tissue types. In some embodiments, the OPO is capable of providing picosecond laser pulses at a wavelength in one of the near-infrared and the infrared region of the electromagnetic spectrum.

Abstract: A neurostimulation system includes an electromyographic (EMG) electrode; a neural electrode implantable in a deep cerebellar nuclei of a subject; a data acquisition unit in communication with the EMG electrode for receiving and transmitting a EMG signal; and a processor in communication with the data acquisition unit, the processor generates a EMG pattern based on the EMG signal and outputs a stimulation signal to the neural electrode when the EMG pattern is indicative of an abnormal motor movement. A method of modulating an abnormal motor movement of a subject by using the neurostimulation system.

Abstract: A biometric apparatus includes a calculation device that processes first time series data from a first measuring device and second time series data from a second measuring device; a display device that displays the time series data; a trigger signal generator that generates one or more trigger signals; and an input unit, wherein the calculation device determines one or more specific intervals of the first time series data based on the one or more trigger signals; configures a classification reference for classifying time series data in the one or more specific intervals using the time series data in a first specific interval using an input signal as a trigger; classifies the second time series data for the one or more specific intervals using a result of classifying the first time series data based on the classification reference; and displays a classification result of the second time series data.

Abstract: Some embodiments relate to a method of adjusting therapeutic stimulation from a therapeutic stimulation system. The method comprising: providing therapeutic stimulation based on a plurality of stimulation parameters to a patient with an implanted controller and at least two electrodes; receiving data indicative of feedback associated with a patient rating of the therapeutic stimulation via a patient input device; automatically adjusting, with the implanted controller, at least one of the plurality of stimulation parameters; and providing adjusted therapeutic stimulation based on the adjusted at least one stimulation parameter to the patient with the controller and the at least two electrodes.

Abstract: A medical handpiece having a laser irradiation unit connected to a body for generating a laser beam, so as to irradiate a subject with the laser beam; a laser tip which is brought into contact with a predetermined surgical site of the subject so as to guide the laser thereto; a sensor installed in the laser tip so as to measure pressure applied by the laser tip to the predetermined surgical site; and a processor for checking whether the measured pressure is within the pressure range set for the predetermined surgical site, determining, according to the result of the checking, whether the pressure applied to the predetermined surgical site needs to be adjusted, and performing control such that a guide signal for the laser tip is output.

Abstract: Systems, methods and computer-readable media are disclosed for providing therapeutic auditory stimulation. Consistent with disclosed embodiments, a system for providing therapeutic auditory stimulation may comprise a diagnostic unit that computes an EEG spectral density of a patient and a heart rate spectral density of a patient and provides values for one or more EEG frequency bands and one or more heart rate frequency bands. The system may also comprise a therapy unit that generates, based on the provided values, one or more stimulation waveforms corresponding to one or more of the EEG frequency bands and provides the stimulation waveforms for therapeutic auditory stimulation. The stimulation waveforms may comprise audible carrier frequencies modulated by signals with frequencies that vary exponentially with time. The EEG frequency bands may comprise the delta, theta, alpha, beta 1, beta 2, and gamma EEG frequency hands.

Abstract: A system and method for extra cardiac defibrillation is disclosed. In a particular embodiment, an extra cardiac implantable cardioverter defibrillator system includes an implantable defibrillator having a metal case and a defibrillation lead. The defibrillation lead has a connector at its proximal end for coupling to the implantable defibrillator and a first defibrillation coil electrode at a distal portion of the lead. The first defibrillation electrode configured to be disposed in an inferior vena cava.

Abstract: Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava.

Abstract: An aspect of the present disclosure relates to an electronic device, and more particularly, to an electronic device that may include: a substrate; a plurality of light emitting devices, disposed on the substrate; a wavelength converting layer, disposed on the substrate, wherein the plurality of the light emitting devices emit a light of same color, wherein light emitted from the light emitting devices is converted by going through the wavelength converting layer, wherein the converted light is extracted to outside of the electronic device, and has a wavelength longer than that of the light emitted from the light emitting devices. Through this, an electronic device can be provided emitting light having a wavelength from which effects of inflammation treatments and skin regeneration can be acquired.

Abstract: An apparatus for estimating bio-information may include a sensor configured to emit light to an object and detect light scattered or reflected from the object and a processor configured to acquire, based on an intensity of the detected light, a first absorbance coefficient change and a first scattering coefficient change, relative to a reference time point, acquire a second scattering coefficient change based on the first absorbance coefficient change, and correct the first scattering coefficient change based on the acquired second scattering coefficient change.

Abstract: Methods of providing electrical neural modulation to a patient's brain are disclosed herein. The methods involve differentially modulating two or more target regions of the brain. For example, a first target region may be provided with an electrical neural modulation signal that activates that target region while a second target region is provided with an electrical neural modulation signal that suppresses or deactivates that target region. As the implantable pulse generators (IPGs) described herein include independent current sources, such differential modulation can be provided with a single IPG.

Abstract: A system is provided for controlling a left univentricular (LUV) pacing therapy using an implantable medical device (IMD). The system also includes one or more processors configured to determine an atrial-ventricular (AV) conduction interval (ARRV) between the A site and a first RV sensed event at the RV site, determine an inter-ventricular (VV) conduction interval (RLV-RRV) between a paced event at the LV site and a second RV sensed event at the RV site, and set a ventricular refractory period (VRP) based on at least one of the AV conduction interval or the VV conduction interval and a predetermined offset. The one or more processors are also configured to blank signals over the RV sensing channel during the VRP.

Abstract: Illustrative methods and devices for providing stimulus to the eye to treat vision disorders. Systems and methods for feedback relating to the stimulus itself as well as the effect of such stimulus on the patient are provided. Various examples may include therapies for vision disorders that can progress to blindness, such as macular degeneration or other diseases and disease processes.

Abstract: An implantable medical device (IMD) has a housing enclosing an electronic circuit. The housing includes a shield member defining a first portion of an interior cavity of the implantable medical device and a skirted feedthrough assembly. The feedthrough assembly includes a shield extender having a top face and a sidewall that extends from the top face so that the top face and the sidewall are a single continuous component. At least one feedthrough aperture extends through the top face.