Abstract: A process for oxidizing alkyl thiols, cycloaliphatic thiols and aralkyl thiols or mixtures thereof to disulfides. The thiol reactant is oxidized by a sulfoxide reactant in the presence of a halogen-hydrogen halide catalyst. The catalysts for the reaction are iodine, hydrogen iodide, bromine, hydrogen bromide, chlorine, hydrogen chloride and mixtures thereof.

Abstract: Novel bis-basic esters and amides of dibenzothiophene of the formula ##SPC1##Wherein:A. each of R.sup.1 and R.sup.2 is hydrogen, (lower)alkyl, cycloalkyl of 3 to 6 ring carbon atoms, alkenyl of 3 to 6 carbon atoms having the vinyl unsaturation in other than the 1-position of the alkenyl group, or each set of R.sup.1 and R.sup.2 taken together with the nitrogen atom to which they are attached is pyrrolidino, piperidino, N-(lower)alkylpiperazino, or morpholino;B. each A is alkylene of 2 to about 8 carbon atoms and separates its adjacent Y and amino nitrogen by an alkylene chain of at least 2 carbon atoms;C. each Y is oxygen, or N--R wherein R is hydrogen or (lower)alkyl of 1 to 4 carbon atoms; or a pharmaceutically acceptable acid addition salt thereof. These compounds can be used as pharmaceuticals for preventing or inhibiting a viral infection.

Abstract: Pharmaceutical compounds of formula I, ##SPC1##in whichP, q, r, and T, which may be the same or different, each represent hydrogen, an alkyl, hydroxy, alkoxy, hydroxyalkoxy, alkoxyalkoxy, acetoxy, carboxy, amino, alkylamino, dialkylamino, alkenyl, p-toluenesulphonyloxy, aralkyl, phenyl, nitro, carboxy ester, alkenyloxy or acyl group, none of which groups contain more than 10 carbon atoms or an adjacent pair of P, Q, R and T, together with the adjacent carbon atoms in the benzene ring may form a fused 5 or 6 membered carbocyclic or oxygen containing heterocyclic ring, andV and W, which are different, each represent oxygen or sulphur.

Abstract: The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-guanidines which are inhibitors of histamine activity.

Abstract: The invention provides 5-homothiochromanyl-(di)-phosphoric (-phosphonic) acid esters of the formula ##SPC1##WhereR.sub.1 is (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4) alkoxy,R.sub.2 is (C.sub.1 -C.sub.4)alkyl,R.sub.3 is hydrogen, (C.sub.1 -C.sub.4)alkyl or halogen, andX is oxygen or sulfur.

Abstract: Compounds characterized by the following formula: ##SPC1##Wherein R and R' can be selected from the group consisting of C.sub.1 to C.sub.15 hydrocarbyl, preferably C.sub.1 to C.sub.6 alkyl, C.sub.3 to C.sub.7 cycloalkyl, phenyl optionally substituted by chlorine, bromine, nitro, cyano, C.sub.1 to C.sub.6 alkyl, C.sub.1 to C.sub.6 alkoxy or C.sub.1 to C.sub.6 alkylthio; R and R' may form together a carbocyclic ring of from 3 to 8 carbon atoms. In addition, R can also be hydrogen. R" can be a C.sub.1 to C.sub.6 alkyl group optionally substituted by chlorine, bromine or cyano; phenyl optionally substituted by chlorine, bromine or nitro, R"' can have the same definition as R" and can be in addition a C.sub.1 to C.sub.6 alkoxy, C.sub.1 to C.sub.4 alkylthio and phenoxy optionally substituted by chlorine, bromine or nitro; X can be oxygen or sulfur.These compounds have been found to possess pesticidal activity, particularly insecticidal, miticidal and nematocidal activity.

Abstract: The invention provides novel cyclic acetals and mercaptals useful as stabilising agents for organic susceptible to degradation by heat or oxygen.

Abstract: 4-(9-Xanthenyl)semicarbazide and thiosemicarbazide, 4-(9-thiazanthenyl)semicarbazide and thiosemicarbazide, and derivatives of these compounds, useful as antisecretory agents.

Abstract: Phenols and thiophenols having an ortho-phenyl substituent react with most aldehydes and ketones in very strongly acidic liquid media to form a dibenzopyran or dibenzothiopyran. The dibenzopyrans, but not the dibenzothiopyrans, can be isomerized to their corresponding fluorenols. The pyran or thiopyran ring can be cleaved chemically or electrochemically to produce phenols and thiophenols which have an ortho substituent in the ortho position of the phenyl substituent of the starting phenol or thiophenol which is characteristic of the aldehyde or ketone reactant. These products as well as the fluorenols, being phenolic bodies, are useful as stabilizers and antioxidants.

Abstract: There are disclosed novel 3-(5-nitro-2-imidazolyl)-pyrazoles exhibiting utility as antibacterial, antiprotozoal, and antifungal agents, making the compounds useful particularly in veterinary medicine, especially in controlling bacterial and protozoal infections of poultry and swine. The compounds are also active as growth promoters in chickens.

Abstract: The compounds of this invention are substituted benzofurans and benzothiophenes having pharmacological activity. In particular, these compounds have coronary vasodilator activity and are useful in the treatment angina pectoris.

Abstract: The present invention provides compounds of formula I, ##SPC1##whereinR.sub.1 is hydrogen, fluorine, chlorine, bromine, hydroxyl, lower alkyl, lower alkoxy, amino or lower acylamino, andR.sub.2 is hydrogen or lower alkyl,Useful as antiphlogistic and anti-arthritic agents.

Abstract: New tricyclic substituted aminoalcohols of the formula: ##SPC1##WhereinX is ethylene, vinylene, oxygen, sulfur, or oxamethylene,A is straight-chained or branched alkylene of from 2 to 5 carbon atoms,R.sub.1 is alkyl of up to 3 carbon atoms; andR.sub.2 is cyclohexyl or phenyl;And the physiologically compatible salts thereof; possess outstanding and valuable cardiac and circulatory activity.

Abstract: A technique for preparing a wide range of fulvalenes by a reductive procedure is described. The procedure involves reducing an organic halide to its corresponding partially hydrogenated derivative which is reacted with fluoboric acid to yield a fluoborate. Deprotonation of the fluoborate yields the desired compound. The described technique maximizes the yield and quality of fulvalenes produced and permits the preparation of thia, selena and tellura fulvalenes.

Abstract: Novel thienobenzopyrans and thiopyranobenzopyrans represented by the formula ##SPC1##Wherein m and n are each 0, 1, 2 or 3 and m + n is 2 or 3; R.sub.1 is loweralkyl; R.sub.2 is alkyl or cycloalkylloweralkyl and R.sub.3 is hydrogen, loweralkyl, loweralkanoyl, carbamyl, N-loweralkylcarbamyl, N,N-diloweralkylcarbamyl, phosphonyl, hemisuccinate or an ester of another such acid, phosphate, dialkylaminoalkyl of the structure ##EQU1## or acid addition salt thereof, or dialkylaminoalkylanoyl of the structure ##EQU2## or acid addition salt thereof, wherein x is 1 through 6 and R.sub.4 and R.sub.5 are loweralkyl; the loweralkyl groups containing from 1 through 6 carbon atoms, the alkyl groups containing from 1 through 20 carbon atoms and the cycloalkyl groups containing from 3 through 8 ring carbon atoms. Novel intermediates for the synthesis of these compounds are also disclosed as well as methods for making the compounds.

Abstract: 1-Ethyl-imidazoles of the formula ##SPC1##Or a pharmaceutically acceptable nontoxic salt thereof, are produced byA. reacting a compound of the formula ##SPC2##With imidazole; orB. when R.sup.1 is hydrogen, reacting a compound of the formula ##SPC3##With imidazole in the presence of an acid binding agent. In the case of the salts the free base produced is reacted with an appropriate acid.The 1-ethyl-imidazoles are useful for their antimycotic activity.

Abstract: Thiophosphates of the formula ##EQU1## where X is 0 or S, R is a hydrocarbon or a substituted hydrocarbon group such as alkyl, aryl, cycloalkyl, alkaryl, aralkyl, etc., and R' is a 3-thione-propene-1 or a substituted 3-thione-propene-1 group; the preparation thereof by reacting a 1,2-dithiolium compound with a phosphite ester; the reversion to the original dithionium compound is effected by reacting the thiophosphate under acid conditions; and the uses of such thiophosphates as corrosion inhibitors in acid systems.

Abstract: There is provided a process for the manufacture of 2-(4-chloro-2-methylphenyl)imino-1,3-dithietane which involves the reaction of a dithiocarbamate salt with a methylene halide in the presence of a base and a sulfide ion in the presence of a ketone solvent to obtain high yields and purity of said 2-(4-chloro-2-methylphenyl)imino-1,3-dithietane.

Abstract: Production of organic sulphoxides by the action of sulphoxides of lower molecular weight on organic sulphides in which the reaction is catalysed by one or more substances capable of supplying hydrogen ions to the reaction medium. The process permits yields to be obtained which exceed 90 percent, and the sulphoxide which is obtained is practically free from sulphone.

Abstract: Novel benzimidazole derivatives of the formula ##SPC1##Wherein R is alkyl of 1 to 2 carbon atoms and R.sub.1 is selected from the group consisting of tetrahydrofurfuryl, a saturated or unsaturated oxygen heterocycle of 4 to 5 carbon atoms and ##EQU1## wherein Z is unsaturated hydrocarbon radical of 2 to 4 carbon atoms having at least 2 halogen atoms which possess fungicidal activity.