Abstract: Methods, systems, and computer readable media for utilizing functional connectivity brain imaging for diagnosis of a neurobehavioral disorder are disclosed. One method for utilizing functional connectivity brain imaging for diagnosis of a neurobehavioral disorder includes receiving brain imaging data for a human subject of a first age, wherein the brain imaging data includes functional connectivity magnetic resonance imaging (fcMRI) data, and predicting, using at least one functional connection between brain locations in the fcMRI data, a neurobehavioral disorder diagnosis for the subject at a second age greater than the first age.

Abstract: A method and system for producing tomosynthetic images of a patient's breast. An x-ray source that delivers x-rays through a breast immobilized and compressed between a compression paddle and a breast platform and form an image at a digital x-ray receptor panel. Multiple x-ray images are taken as the x-ray source and the receptor move relative to the immobilized breast. In one preferred embodiment, the x-ray source travels from ?15° to +15°. The source can travel in an arc around the breast while the receptor travels linearly while remaining parallel and at the same distance from the breast platform. The sets of x-ray image data taken at different angles are combined to form tomosynthetic images that can be viewed in different formats, alone or as an adjunct to conventional mammograms.

Abstract: A magnetic resonance imaging system (100) for acquiring magnetic resonance data (141) from an imaging zone (108) includes a memory (134, 136) for storing machine executable instructions (150, 152, 154, 156) and pulse sequence commands (140). The pulse sequence commands cause the magnetic resonance imaging system to provide at least one spatially selective saturation pulse (408, 410) to at least one selected volume (124, 124?) that is at least partially outside of a region of interest (123) and within the imaging zone. The magnetic resonance imaging system performs a non-selective inversion (412) of spins in the region of interest followed by a readout (414) of the magnetic resonance data which is reconstructed (202) into an image (142).

Abstract: A system for analyzing tissue includes a platform and an optical sensing unit coupled to the platform. The optical sensing unit has a detector and a plurality of light sources surrounding and electrically isolated from the detector. The optical sensing units obtain optical data for tissue analysis.

Abstract: An acoustic wave detector detects photoacoustic waves generated by absorbing measurement light emitted toward a subject, and reflected acoustic waves with respect to acoustic waves transmitted toward the subject. A preamplifier amplifies a detection signal output by the acoustic wave detector. A bypass unit is intended to output the detection signal without passing through the preamplifier. Controller causes the preamplifier to enter an operating state and selects a first path along which the detection signal is amplified by the preamplifier and then is input to the reception circuit as a signal path in a case where the photoacoustic waves are detected. The controller stops an amplification operation in the preamplifier and selects a second path along which the detection signal is input to the reception circuit via a bypass unit as the signal path in a case where reflected acoustic waves are detected.

Abstract: An apparatus, including a magnetic field generator, a first magnetic field sensor configured for attachment to a proximal end of a surgical tool configured for insertion into a body, and a calibration device that includes a second magnetic field sensor and a proximity sensor, wherein the field sensors generate respective location signals responsive to a magnetic field emanating from the generator and traversing the field sensors. The apparatus includes a control unit, which receives the signals from all the sensors, extracts respective location and orientation coordinates of the field sensors based on the signals, computes a conversion relation between the coordinates of the first sensor and a distal end of the tool that is brought into contact with the calibration device, and subsequently applies the conversion relation, together with the coordinates of the first sensor, in providing a visual indication of a location of the distal end inside the body.

Abstract: A method of ultrasonically imaging an object includes providing a 2D array of bias-sensitive ultrasound transducer elements. Each ultrasound transducer element has first and second electrodes on first and second sides of the ultrasound transducer connected in plural first and second electrode strips. The plural first electrode strips are oriented at an angle to the plural second electrode strips. A biasing pattern is applied to a plurality of the second electrode strips and generating a series of transmit events in one or more first electrode strips. Return pulses are detected by measuring received signals from biased second electrode strips. For the series of transmit events, the second electrode strips are biased according to sequential biasing patterns of voltages that correspond to rows or columns of an invertible matrix. The measured received signals are processed to generate an image of the object.

Abstract: The method of the invention determines a physical characteristic on a punctual location inside a medium, and includes including the steps of sending an emitted sequence having emitted pulses that have different amplitudes, receiving a received sequence having received pulses corresponding to echoes of the emitted pulses, calculating a phase difference between the received pulses relative to the emitted pulses, and determining the physical characteristic on the punctual location on the bases of said the phase difference.

Abstract: In a method and apparatus for supporting a user when positioning an accessory for a magnetic resonance examination on an examination object, the actual position of the accessory is acquired by an acquisition unit, and a target position of the accessory is determined by a determination unit. The actual position and the target position of the accessory are compared with regard to deviation of the actual position from the target position of the accessory. Output information representing any deviation that is found to exist is provided to a user via an output unit.

Abstract: Physiological parameter detecting apparatuses and methods of detecting the physiological parameters are provided. A physiological parameter detecting apparatus includes: a light source configured to emit a light onto a region of an object; an optical path converter configured to receive the light returning from the object and convert an optical path of the received light; an optical detector configured to detect the light that has the converted optical path; and a controller configured to extract physiological information of the object from the detected light.

Abstract: An ultrasonic diagnostic apparatus according to an embodiment includes calculation circuitry, acquisition circuitry, determination circuitry, and scan control circuitry. The calculation circuitry calculates an indicator related to motion of biological tissue in a subject, based on echo data obtained through a pre-scan for the subject. The acquisition circuitry acquires a periodic biological signal of the subject. The determination circuitry specifies at least one tune phase in one cycle of the biological signal acquired during the pre-scan, based on the indicator, and determines a timing of a main scan for the subject, based on the specified time phase and the biological signal acquired after the pre-scan. The scan control circuitry executes the main scan at the timing determined by the determination circuitry.

Abstract: An external ultrasonic probe includes a transducer array including multiple transducers arranged along an azimuth direction, the multiple transducers transmitting and receiving ultrasonic waves; and a covering material having a projecting surface touchable with a living body, formed of a single member, covering an entire front-surface side of the transducer array, and covering at least a part of a side-surface side of the transducer array. In a section dividing a width of the transducer array in the azimuth direction substantially into two equal parts, a width between two points on the projecting surface falling down from a top of the projecting surface by 2 mm is larger than a width of the transducer array in an elevation direction. A difference between the width between the two points and the width of the transducer array in the elevation direction is 5 mm or less.

Abstract: A method for high spatial and temporal resolution dynamic contrast enhanced magnetic resonance imaging using a random subsampled Cartesian k-space using a Poisson-disk random pattern acquisition strategy and a compressed sensing reconstruction algorithm incorporating magnitude image subtraction is presented. One reconstruction uses a split-Bregman minimization of the sum of the L1 norm of the pixel-wise magnitude difference between two successive temporal frames, a fidelity term and a total variation (TV) sparsity term.

Abstract: Provided is a non-invasive system and method of determining muscle tissue size based on image processing. The method includes receiving at least one ultrasound scan image of at least a portion of a skin layer as disposed above one or more additional tissue layers, the image provided by a plurality of pixels. The method continues by introducing noise into the pixels of the image and thresholding the pixels of the image to provide a binary image having a plurality of structural elements of different sizes. The method continues with morphing the structural elements of the binary image to remove small structural elements and connect large structural elements. With this resulting image, the method distinguishes muscle tissue from remaining elements and determines the muscle tissue size. Associated apparatuses and computer program products are also disclosed.

Abstract: An ultrasound signal processing device: performing transmission events each involving selecting a group among transducer elements arranged in line in an ultrasound probe, and causing the group to transmit ultrasound towards a subject; for each transmission event, receiving ultrasound reflection from the subject; and generating a frame acoustic line signal based on sub-frame acoustic line signals that are generated based on the ultrasound reflection. The ultrasound signal processing device includes: a calculator that calculates, based on reflected ultrasound, a motion amount indicating movement between image signals for the subject; and a synthesizer generating the frame acoustic line signal based on the sub-frame acoustic line signals. The number of sub-frame acoustic line signals that the synthesizer uses to generate a frame acoustic line signal decreases when the motion amount is equal to or greater than a predetermined threshold.

Abstract: Diffuse optical flow (DOF) sensors can be used to assess deep tissue flow. DOF sensors positioned on a foot can provide fluctuating light intensity data to an analyzer, which can then determine absolute and/or relative blood flow. The determined absolute and/or relative blood flow can be signaled to an operator, for example a surgeon for intra-operative use. DOF sensors may be utilized to assess pedal revascularization, for example to guide interventional procedures and to evaluate their efficacy. A support structure can carry a plurality of DOF sensors, such that when the support structure is placed onto a patient's foot, the DOF sensors are disposed adjacent different locations on the foot. The different locations may correspond to different topographical regions of the foot, for example different pedal angiosomes.

Abstract: A method of identifying and locating tissue abnormalities in a biological tissue includes irradiating an electromagnetic signal, via a probe defining a transmitting probe, in the vicinity of a biological tissue. The irradiated electromagnetic signal is received at a probe, defining a receiving probe, after the signal is scattered/reflected by the biological tissue. Blood flow information pertaining to the biological tissue is provided. Based on the received irradiated electromagnetic signal and the blood flow information, tissue properties of the biological tissue are reconstructed. A tracking unit determines the position of at least one of the transmitting probe and the receiving probe while the step of receiving is being carried out, the at least one probe defining a tracked probe. The reconstructed tissue properties are correlated with the determined probe position so that tissue abnormalities can be identified and spatially located.

Abstract: Systems and methods are provided for in vivo pre-surgical characterization of lenses, such as cataractous lenses. A method comprises obtaining an electromagnetically-measured value related to the axial thickness of the lens, obtaining an ultrasound-measured value related to the axial thickness of the lens, calculating a relationship value based upon the electromagnetically-measured value and the ultrasound-measured value, and determining a mechanical property value based upon the calculated relationship value. The mechanical property may relate to lens hardness, rigidity, or density, or the amount of energy for a phacoemulsification procedure. A system may comprise an optical interferometer for measuring data to obtain the electromagnetically-measured value and an ultrasound biometer for measuring data to obtain the ultrasound-measured value.

Abstract: According to one embodiment, an ultrasonic diagnostic apparatus includes an ultrasonic probe, position detector detecting a probe position, ultrasonic image generation circuitry generating an ultrasonic image, storage circuitry storing volume data and a designation position in association with each other, slice image generation circuitry generating a slice image to the designation position based on the data and the designation position, a display displaying at least one of first display displaying the slice image and the ultrasonic image and second display displaying contents different from contents in the first display, control circuitry controlling switching from the first display to the second display in response to movement of the probe position into a range to the designation position.

Abstract: A needle guide for an ultrasonic probe is disclosed. The needle guide includes a pair of pivotable jaws mounted at the end of a pair of elongated arms. The jaws establish a tapering gap between them for receipt of the working head of the ultrasound probe. The needle guide also includes a needle holding section having plural angled slots or channels, each of which is configured for receipt of a needle therein to guide the needle along a respective desired path to a position below the working head of the ultrasound probe so that it can be imaged thereat. The needle guide can be operated by one hand.