Patents Examined by Christopher Adam Hixson
  • Patent number: 10844298
    Abstract: A method for recalculating the solvent power of a light oil, SP(LO recalculated), is provided.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: November 24, 2020
    Assignee: BP Corporation North America Inc.
    Inventors: Soban Balashanmugam, Ronald Fisher, Rosa Rueda-Velásquez, Devin Halliday
  • Patent number: 10845372
    Abstract: A cancer evaluation method includes a step S1 of measuring the concentrations of a set of evaluation elements in a serum sample 2 taken from a subject, a step S2 of applying the concentration data of the set of elements to a predetermined discriminant function to perform an operation; and a step S3 of discriminating whether or not the subject suffers from any type of cancer based on the operation result obtained using the concentration data and the discriminant function. The discrimination is carried out in accordance with the concentration balance (pattern) of the set of elements. Preferably, the set of elements are 7 elements of S, P, Mg, Zn, Cu, Ti, and Rb, or 16 elements of Na, Mg, Al, P, K, Ca, Ti, Mn, Fe, Zn, Cu, Se, Rb, Ag, Sn, and S.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: November 24, 2020
    Assignee: RENATECH CO., LTD.
    Inventors: Seiichi Inagaki, Naoyuki Okamoto
  • Patent number: 10835148
    Abstract: Particular aspects of the invention are methods for assaying metabolite levels in samples from a patient during pregnancy using nuclear magnetic resonance and direct flow injection mass spectrometry. In various methods, the assayed metabolites may be acylcarnitine or one or more of C3-OH (hydroxypropionylcarnitine), C5-OH (C3DC), C10, C5:1-DC (glutaconylcarnitine), C14:1-OH (hydroxytetradecenoylcarnitine) and C14:2-OH. One or more methods also may include measuring nuchal translucency of the fetus. Other methods relate to predicting fetal congenital heart defects in a fetus.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: November 17, 2020
    Assignee: Bioscreening & Diagnostics LLC
    Inventors: Ray O. Bahado-Singh, Kypros Nicolaides
  • Patent number: 10830722
    Abstract: Embodiments of the present disclosure describe a gas sensor comprising a gas-sensing material including a metal-organic framework with fcu topology and a substrate with a pair of electrodes proximate to the gas-sensing material, wherein the gas sensor is configured to detect toxic gas. Embodiments of the present disclosure further describe a method of detecting gas comprising contacting a gas sensor including a metal-organic framework with fcu topology with a gas/vapour composition including at least one toxic gas, capturing the at least one toxic gas from the fluid composition, and measuring an electrical property to detect a presence of the at least one toxic gas.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: November 10, 2020
    Assignee: KING ABDULLAH UNVIERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Omar Yassine, Osama Shekhah, Youssef Belmabkhout, Mohamed Eddaoudi, Khaled N. Salama
  • Patent number: 10828633
    Abstract: Disclosed here are pipette tips useful for acquiring or dispelling liquids, and include one or more design that may increase fluid delivery precision and/or accuracy, and may reduce certain repetitive motions.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: November 10, 2020
    Assignee: BIOTIX, INC.
    Inventors: Arta Motadel, Peter Paul Blaszcak, Phillip Chad Hairfield, Sean Michael Callahan
  • Patent number: 10823716
    Abstract: A measured wetness of and a ?13C associated with a gas sample from a hydrocarbon formation is received wherein the wetness is a percentage of C2+ by mass. Calculated wetnesses of and ?13C values associated with a plurality of gas samples taken from one or more analogous hydrocarbon reservoirs is received. Each wetness is calculated as a percentage of mass within the gas sample. The measured wetness received for the gas sample from among the calculated wetnesses is identified. A ?13C is determined from among the ?13C values that corresponds to the measured wetness of the gas sample. A gas maturity for the gas sample is determined using the determined ?13C.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: November 3, 2020
    Assignee: Saudi Arabian Oil Company
    Inventor: Feng Hu Lu
  • Patent number: 10823674
    Abstract: A fluorescent nanocomposite which includes a thallium doped gadolinium chalcogenide having formula TlxGd1-xY, wherein x is 0.01 to 0.1, and Y is selected from the group consisting of S, Se, or Te, and a benzothiazolium salt bound to a surface of the thallium doped gadolinium chalcogenide. A method of detecting antimony ions in a fluid sample whereby the fluid sample is contacted with the fluorescent nanocomposite to form a mixture, and a fluorescence emission profile of the mixture is measured to determine a presence or absence of antimony ions in the fluid sample, wherein a reduction in intensity of a fluorescence emissions peak associated with the fluorescent nanocomposite indicates the presence of antimony ions in the fluid sample.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: November 3, 2020
    Assignee: King Abdulaziz University
    Inventors: Waleed Elsayed Mahmoud Elsayed, Ahmed Abdullah Salem Al-Ghamdi, Yusuf Abdulaziz Al-Turki
  • Patent number: 10816443
    Abstract: An automated batch stainer for staining biological specimens on microscope slides. The automated batch stainer includes a slide rack assembly configured to hold microscope slides, a robotic arm that manipulates the slide rack assembly, at least one bath containing reagents and capable of receiving the slide rack assemblies, a heating chamber capable of heating multiple slide rack assemblies, a bar code reader, at least one software program including a graphical user interface and configured to calculate the timing and sequence of the staining protocol and implement the staining protocol by controlling the movements of the robotic arm.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: October 27, 2020
    Inventors: Kamal Prasad Peddinti, Neeraj Kumar
  • Patent number: 10816493
    Abstract: Provided is a technique that allows high-accuracy electrical measurement without the influence of blood sedimentation in a case where various measurements or evaluations are performed using blood samples containing a blood cell component and a plasma component. Provided is an electrical measurement method for electrically measuring a blood sample including at least a blood cell component and a plasma component, the electrical measurement method including the step of adding a blood sedimentation inhibitor to the blood sample. Also provided is a blood sedimentation inhibitor for use in electrical measurement of a blood sample including at least a blood cell component and a plasma component, the blood sedimentation inhibitor including a non-cationic water-soluble compound and being capable of increasing specific gravity and/or viscosity of the plasma component.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: October 27, 2020
    Assignee: SONY CORPORATION
    Inventors: Seungmin Lee, Kenzo Machida, Kaori Kawaguchi, Marcaurele Brun
  • Patent number: 10816517
    Abstract: The present invention provides a novel method that is capable of detecting a trifluridine-related substance from a sample containing trifluridine or a salt thereof by high-performance liquid chromatography comprising two steps that are performed under gradient conditions. More specifically, the method is for detecting a trifluridine-related substance, the method comprising the step of subjecting a sample containing trifluridine or a salt thereof to high-performance liquid chromatography using a mobile phase composed of an organic phase and an aqueous phase, wherein the step of high-performance liquid chromatography comprises steps 1 and 2 that satisfy the following requirements: Step 1: the percentage of the organic phase in the entire mobile phase is 1 to 14% by volume; and Step 2: after step 1, elution is performed by applying a gradient of increasing the percentage of the organic phase in the entire mobile phase.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: October 27, 2020
    Assignee: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Daisuke Takeda, Akiyo Kojima
  • Patent number: 10809270
    Abstract: The present disclosure relates to methods for screening and identifying a fetal trisomy. Certain embodiments of the present disclosure provide a method of screening for a fetal trisomy in a pregnant female subject. The method comprises detecting one or more lipid markers from the subject, wherein the one or more markers is indicative of the risk of a fetal trisomy in the subject, and determining the risk of a fetal trisomy in the pregnant female subject on the basis of the one or more lipid markers detected.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: October 20, 2020
    Assignee: AUSHEALTH CORPORATE PTY LTD
    Inventors: Enzo Ranieri, Steven Ramsay, Peter Charles Kinmont Sharp, Janice Fletcher
  • Patent number: 10809241
    Abstract: Apparatuses and methods of measuring a hydrogen diffusivity of a metal structure including during operation of the metal structure, are provided. A hydrogen charging surface is provided at a first location on an external surface of the structure. In addition, a hydrogen oxidation surface is provided at a second location adjacent to the first location on the external surface of the structure. Hydrogen flux is generated and directed into the metal surface at the charging surface. At least a portion of the hydrogen flux generated by the charging surface is diverted back toward the surface. A transient of the diverted hydrogen fluxes measured, and this measurement is used to determine the hydrogen diffusivity of the metal structure in service.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: October 20, 2020
    Assignee: SAUDI ARABIAN OIL COMPANY
    Inventors: Abderrazak Traidia, Mohammed Alshahrani, Sebastien A. Duval
  • Patent number: 10809237
    Abstract: The present invention provides a novel method that is capable of detecting a trifluridine-related substance from a sample containing trifluridine or a salt thereof by high-performance liquid chromatography comprising two steps that are performed under gradient conditions. More specifically, the method is for detecting a trifluridine-related substance, the method comprising the step of subjecting a sample containing trifluridine or a salt thereof to high-performance liquid chromatography using a mobile phase composed of an organic phase and an aqueous phase, wherein the step of high-performance liquid chromatography comprises steps 1 and 2 that satisfy the following requirements: Step 1: the percentage of the organic phase in the entire mobile phase is 1 to 14% by volume; and Step 2: after step 1, elution is performed by applying a gradient of increasing the percentage of the organic phase in the entire mobile phase.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: October 20, 2020
    Assignee: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Daisuke Takeda, Akiyo Kojima
  • Patent number: 10809196
    Abstract: A quencher containing water-soluble polymer-conjugated nanomaterial effectively quenches the fluorescence of a fluorescent material-conjugated probe. In addition, a composition including the quencher and a fluorescent material-conjugated probe can detect a target material existing at a low concentration, and thus can be favorably used as a composition or kit for providing information necessary for the detection of a biomaterial or the diagnosis of a disease.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: October 20, 2020
    Assignee: LEMONEX INC.
    Inventors: Cheolhee Won, Dal-Hee Min
  • Patent number: 10809168
    Abstract: This disclosure is directed to a system and method relevant to sampling halosilanes or other water-reactive samples. In embodiments, a system for hydrolyzing samples includes a container with a receiving liquid (e.g., an HF solution) contained therein and an actuator coupled with the container. The actuator can be configured to rotate the container, thereby inducing a vortex in the receiving liquid. The system further includes a sample tube configured to direct a halosilane sample into the vortexed receiving liquid. The sample tube can be oriented to release the sample in a flow direction of the vortexed receiving liquid.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: October 20, 2020
    Assignee: ELEMENTAL SCIENTIFIC, INC.
    Inventor: Daniel R. Wiederin
  • Patent number: 10802033
    Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: October 13, 2020
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Mario Becker, Gerhard Greller, Christian Grimm, Thorsten Adams, Lars Boettcher, Henry Weichert
  • Patent number: 10800799
    Abstract: Methods, kits and devices for separating phospholipids and proteins from small molecules in biochemical samples can feature an apparatus having a wetting barrier, at least one frit and a separation media. For example, an apparatus can include at least one wall defining a chamber having an exit and an entrance; a wetting barrier disposed between the exit and entrance, so as to define a separation media space located between the wetting barrier and the exit and a sample receiving area located between the wetting barrier and the entrance; and a separation media disposed adjacent to the wetting barrier and having a specific affinity for phospholipids.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: October 13, 2020
    Assignee: Waters Technologies Corporation
    Inventors: Pamela C. Iraneta, Thomas H. Walter, Xin Zhang, Daniel P. Walsh, Kevin D. Wyndham, Raymond P. Fisk
  • Patent number: 10801995
    Abstract: An exemplary embodiment of a method of detecting hydrocarbons in Systems and methods for sensing analytes in an aqueous solution, include pretreating a water sample to provide a test sample. A flow cell includes at least one sensor with a polymer coating having at least partial selectivity for at least one analyte. The flow cell receives a test sample and a reference sample. At least one output signal from the at least one sensor is processed with a microcontroller using a model of the sensor response and a bank of Kalman filters to estimate a concentration of at least one analyte in the aqueous solution.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: October 13, 2020
    Assignees: Marquette University, Chevron U.S.A. Inc.
    Inventors: Fabien J. Josse, Florian Bender, Antonio J. Ricco, Rachel Ellen Mohler, Ravindra Vasant Kolhatkar
  • Patent number: 10801930
    Abstract: A method for preparing a sample for chromatographic separation processes, in which a sample vessel is partially filled with a substance to be examined and is closed, is described. The substance to be examined is subjected to a thermo-chemical reaction in which at least one sample component is converted into another substance, and in which by use of a removing device samples are removed from the sample vessel for analytical examination. Also, the sample vessel forms a cavity, into which the substance to be examined is introduced as a core and a heating section for indirect heat transfer is applied along the filling of substance to be examined.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: October 13, 2020
    Assignee: Gerstel Systemtechnik GmbH & Co. KG
    Inventors: Patrick Sandra, Bart Tienpont, Frank David, Tom Sandra, Koen Sandra
  • Patent number: 10794877
    Abstract: A sorbent tube apparatus (10) for high-pressure fluid sample analysis, the sorbent tube apparatus (10) comprising a pressurisable housing (32) having first and second fluid ports (48a, 48b) and defining a fluid chamber (34) therein; and a sorbent tube (12) mountable within the pressurisable housing (32), the sorbent tube (12) extending from one of the first and second fluid ports (48a) and spaced apart from the other of the first and second fluid ports (48b) to be in fluid communication with the fluid chamber (34), thereby enabling in use pressure equalisation between the sorbent tube (12) and fluid chamber (34). A method of analysing high-pressure fluid, an analytic probe apparatus, a further sorbent tube apparatus and method of preventing or limiting damage to a sorbent tube during high-pressure fluid sampling are also provided.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: October 6, 2020
    Assignee: EnDet Limited
    Inventor: Jeremy Knight