Abstract: An operating-room-cable assembly includes a lead connector with a lead-connector housing for receiving a lead. The lead-connector housing includes a first housing element and a second housing element that slide relative to one another to transition the lead-connector housing between an open position and a closed position. A connector port is defined in the lead-connector housing and includes a first surface formed by the first housing element and a second surface formed by the second housing element. A lead retainer is disposed along the second surface and receives the lead when the lead-connector housing is in the open position. Connector contacts are disposed along the first surface. The connector contacts couple to terminals disposed along the lead when the lead is received by the lead retainer and the lead-connector housing is in the closed position. Operating-room-cable conductors are coupled to the connector contacts and extend along the elongated body.

Abstract: Electrical energy delivery tissue site validation systems and methods can determine an indication of a tissue type at a tissue site. This information can be used to enable or inhibit electrical energy delivery to the tissue site. The tissue type at the tissue site can be determined such as by delivering a test electrical energy and sensing a responsive electrical energy. An electrical connectivity to the tissue site can also be determined, such as by using a sensed intrinsic electrical signal at the tissue site. Tissue type information may be communicated externally, such as to allow user confirmation or override of the determined indication of tissue type at the tissue site, such as by a physician, user, or other operator.

Abstract: What is disclosed is a system and method for extracting photoplethysmographic (PPG) signal (i.e., a cardiac signal) on a continuous basis from a time-series signals obtained from video images captured of a subject being monitored for cardiac function in a non-contact remote sensing environment involves the following. First, a time-series signal obtained from video images captured of a region of exposed skin where a photoplethysmographic (PPG) signal of a subject of interest can be registered. A sliding window is then used to define consecutive sequential segments of the time-series signal for processing. Each of the consecutive time-series signal segments is detrended such that low frequency variations and non-stationary components are removed. The detrended signals are processed to obtain, for each segment, a PPG signal. The PPG signal segments are then stitched together using a stitching method, as disclosed herein, to obtain a continuous PPG signal for the subject.

Abstract: A programming-device user interface may include multiple levels of abstraction for programming treatment settings. A stimulation zone-programming interface may be at a highest level of abstraction and may include idealized stimulation zones. A field strength-programming interface may be at a middle level of abstraction and may include electromagnetic field-strength patterns generated by the stimulation zones, and/or electrode settings, and a depiction of how the electromagnetic fields interact with each other. An electrode-programming interface may be at a lowest level of abstraction and may depict treatment settings at an electrodes-view level. These interfaces may include a display of a stimulatable area of the patient's body. The display may include a depiction of leads and/or the underlying physiology, such as a depiction of a portion of a spine. Algorithms map treatment settings from one level of abstraction to settings at one or more other levels of abstraction.

Abstract: A method for passivating a biomaterial surface includes modifying proteinaceous material disposed at the biomaterial surface. The passivation may be effectuated by exposing the biomaterial surface to therapeutic electrical energy in the presence of blood or plasma.

Abstract: An electric stimulator includes a housing, a control circuit board, and at least two electrode plates. The housing includes an internal space formed therein and an outside surface in which at least one electrode plate retention slot is formed. The control circuit board is mounted in the internal space of the housing to control intensity and frequency of a current output. The electrode plates are electrically conductive and are received in the electrode plate retention slot of the housing and are in electric connection with the control circuit board. The electrode plates have an outside surface including a large-area contact surface and a small-area contact surface connected to the large-area contact surface. The large-area contact surface has a surface area greater than that of the small-area contact surface. The large-area contact surface and the small-area contact surface define therebetween an inclined angle that is not equal to 180 degrees.

Abstract: Provided herewith are methods and apparatus for optimizing an atrioventricular (AV) pacing delay interval. One manner described involves dynamically programming an AV interval in cardiac resynchronization therapy (CRT) device having a rate-adaptive AV (RAAV) feature in such a way that not less than a minimum AV interval is maintained. That is, the AV interval is not allowed to be reduced so much that the P-wave is truncated by the QRS complex. In this form of the invention, the AV interval is reduced by one millisecond per one bpm increase in heart rate (and vice versa for reducing heart rate) but maintained at a value calculated from the end of the P-wave (PWend) and the beginning of the QRS complex (QRSbeg) or delivery of a ventricular pacing stimulus or to the end of the end of the QRS complex (QRSend).

Abstract: An electrosurgical forceps is provided with a shaft that extends from a housing of the electrosurgical forceps. An end effector assembly includes a pair of first and second jaw members pivotably coupled to one another via a pivot pin. One or both of the first and second jaw members may be movable from an open position for positioning tissue therebetween to a clamping position for grasping tissue. A detent is operably disposed proximal the pivot pin and extends radially outward from a proximal flange of one of the jaw members. The detent is configured to releasably engage a corresponding slot disposed on a proximal flange of the other jaw member. The detent and slot are configured to control a gap distance between the first and second jaw members when the first and second jaw members are in the clamping position.

Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.

Abstract: An implantable medical device detects conditions such as a lead failure which may result in oversensing a physiologic condition. In response, the IMD automatically adjusts sensing thresholds, such as the number of intervals to detection in order to mitigate the effect of oversensing in the delivery of extraneous therapy.

Abstract: Software and apparatus are provided to automatically detect and map areas of complex fractionated electrograms within cardiac chambers. Electrogram signal are analyzed to count the number of complexes whose amplitude and peak-to-peak intervals meet certain criteria. Functional maps indicating average complex interval, shortest complex interval, and confidence levels are produced for display.

Abstract: A prosthetic hearing implant kit is disclosed. The prosthetic hearing implant kit comprises internal components configured to be implanted in a recipient and comprises an internal coil; external components configured to be worn by the recipient and comprises an external coil adapted to be inductively coupled with said internal coil; and an alert system having a second external coil and adapted to receive an external alarm and to transmit signals to said implanted components via said external coil for providing the recipient with a corresponding alarm indication.

Abstract: A brain implant device includes a housing containing communication and control electronics coupled to a conduit configured for monitoring signals from a brain's motor cortex and providing stimulation signals to the brain's sensory cortex. The brain implant device is capable of wireless communication with an external communication and control signal source by means of an antenna provided in the housing. The conduit is flexible and may contain upwards of 128 electrical conductors providing electrical connections between the device electronics and related sites on the motor and/or sensory cortex by means of a plurality of electrically conductive protuberances extending from the conduit and adapted for contact with such sites.

Abstract: A neuromodulation system and method of providing sub-threshold therapy to a patient. An anodic perception threshold of super-threshold electrical energy and a cathodic perception threshold of super-threshold electrical energy are determined for a plurality of electrode sets. A ratio between the anodic perception threshold and the cathodic perception threshold is calculated for each of the electrode sets. An effective electrode set is selected based on the ratio between the anodic perception threshold and the cathodic perception threshold.

Abstract: One aspect of the present disclosure includes a method for treating chronic or refractory rhinitis in a subject. One step of the method includes implanting a therapy delivery system in the subject so that at least one therapy delivery component of the system is positioned substantially adjacent a target location where modulation of the autonomic nervous system (ANS) is effective to treat chronic or refractory rhinitis. The therapy delivery component includes at least one electrode configured to deliver electric current to the target location. Next, electric current is delivered to the at least one electrode to effect a change in the ANS.

Abstract: A dynamically adjustable multiphasic pulse system and method are provided. The dynamically adjustable multiphasic pulse system may be used as pulse system for a defibrillator or cardioverter. The dynamically adjustable multiphasic pulse system may generate a positive phase and a negative phase of a pulse to generate a therapeutic pulse.

Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

Abstract: A procedure and apparatus to determine the overall fitness of a test subject. For this purpose the qualitative and temporal progression of the heart rate under constant physical stress of the subject is prescribed with at least one parameter dependent on the subject. The heart rate of the subject is measured under constant physical stress during a period of time. The parameter(s) are determined from the measured values, and the maximum heart rate and/or the initial heart rate and/or the increase characteristic of the heart rate are determined from the function and the measured values by numerical procedures. The apparatus can measure the heart rate of the subject, record a temporal progression of the heart rate under physical stress, and determines numerically from the temporal progression of the heart rate, the maximum heart rate and/or the initial heart rate without physical stress and/or the increase characteristic of the heart rate.

Abstract: One aspect of the present disclosure relates to a method for modulating, suppressing or preventing a dermatological disorder in a subject. One step of the method can include positioning at least one electrode on or proximate to at least one of a sphenopalatine ganglion (SPG), a sphenopalatine nerve (SN), a vidian nerve (VN), a greater petrosal nerve (GPN), a deep petrosal nerve (DPN), or a branch thereof, of the subject. Next, the at least one electrode can be activated to apply an electrical signal to at least one of the SPG, the SN, the VN, the GPN, the DPN, or the branch thereof.

Abstract: A system for monitoring physical activity, in which activity data for an individual is be captured and stored whether the activity takes place in a health club or away from the health club (e.g. outdoors). The proposed approach is to capture heart rate data using an individual heart rate monitor (e.g. a chest belt) that has inbuilt memory for storing the heart rate data. The data is uploaded from the belt to a database, preferably a database that is accessible over the Internet, via a receiver station that will typically be located in a health club where the user is a member.