Patents Examined by Christopher R. Tate
  • Bioactive peptides
    Patent number: 8143211
    Abstract: The present invention provides a cytotoxic 7 to 25-mer peptide with three or more cationic residues which has one or more non-generic bulky and lipophilic amino acids, as well as esters, amides, salts and cyclic derivatives thereof as well as methods of preparing the peptides, pharmaceutical compositions containing them, and their use as medicaments, particularly as antibacterial or antitumor agents.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: March 27, 2012
    Assignee: Lytix Biopharma AS
    Inventors: John Sigurd Svendsen, Øystein Rekdal, Baldur Sveinbjørnsson, Lars Vorland
  • Oral composition containing oxidized
    Patent number: 8137713
    Abstract: Oral composition comprising a Camellia extract of semi-oxidized tissue from a member of the genus Camellia and an enhancing agent.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: March 20, 2012
    Assignee: Colgate-Palmolive Company
    Inventors: Thomas J. Boyd, Abdul Gaffar, David Viscio
  • Rehydration beverage
    Patent number: 8137712
    Abstract: The present invention relates to a composition for the relief of hangover symptoms and methods of treating hangover symptoms.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: March 20, 2012
    Inventor: Evan Hays
  • Insecticidal composition
    Patent number: 8137715
    Abstract: The use of dill oil or a mixture of two or more components thereof as a potentiator for a pesticide, such as an insecticide and in particular a pyrethroid is described, together with compositions containing dill oil, and their use in agriculture and in veterinary applications.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: March 20, 2012
    Assignee: Livie Biopesticides Limited
    Inventors: Sujay Anil Shah, Christopher William Horsler
  • Therapeutic ultrasound gel
    Patent number: 8133516
    Abstract: The therapeutic ultrasound gel is a composition that lubricates the abdomen for ultrasound scanning, that enhances the transmission of sound waves during ultrasound diagnostic imaging, and that has beneficial therapeutic effects in preventing the formation of stretch marks. The composition contains effective amounts of aloe vera (Aloe barbadensis), glycerin, and various agents for preventing the formation of stretch marks, with the balance being sufficient water to adjust the consistency of the composition. The composition may also be formulated for home use, chiefly by the addition of vitamin D3 or, alternatively, vitamin K. Either formulation may contain additional excipients, including surfactants, emulsifiers, humectants, stabilizers, thickeners, pH balancers, preservatives, colorants, and scent, if desired.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: March 13, 2012
    Inventor: Scott D. Lauer
  • CLK-peptide and SLK-peptide
    Patent number: 8133471
    Abstract: The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured collagen type-IV with substantially greater affinity than to the native triple helical form of collagen type-IV. Methods utilizing such antagonists for therapeutic treatment of tumor growth, tumor metastasis or of restenosis also are described, as are methods to use such antagonists as diagnostic markers of angiogenesis in normal or diseased tissues both in vivo and ex vivo. The invention further describes methods for treating tumors using said antagonists in combination with radiation therapy and therapies comprising the antagonists and radiation treatment.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: March 13, 2012
    Assignee: New York University
    Inventors: Peter C. Brooks, Jennifer Roth, Abebe Akalu
  • Compositions comprising epigallocatechin gallate and protein hydrolysate
    Patent number: 8129337
    Abstract: The present invention describes a composition comprising EGCG and a protein hydrolysate.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: March 6, 2012
    Assignee: DSM IP Assets B.V.
    Inventor: Swen Wolfram
  • Production of mustard seed protein isolate
    Patent number: 8128974
    Abstract: Mustard seed protein isolates are produced at a high purity level of at least about 100 wt % (N×6.25) by a process wherein mustard seed protein is extracted from mustard seed meal, the resulting aqueous mustard seed protein solution is concentrated to a mustard seed protein content of at least about 200 g/L, and the concentrated mustard seed protein solution is added to chilled water having a temperature below about 15° C. to form mustard seed protein micelles, which are settled to provide a mustard seed protein micellar mass (PMM). The mustard seed protein micellar mass is separated from supernatant and may be dried.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: March 6, 2012
    Assignee: Burcon Nutrascience (MB) Corp.
    Inventors: Larry D. Barker, Ronald W. Martens, E. Donald Murray
  • Processes for intermediates for macrocyclic compounds
    Patent number: 8129561
    Abstract: The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as describe in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: March 6, 2012
    Assignee: Tranzyme Pharma Inc.
    Inventors: Eric Marsault, Luc Ouellet, Hamid R. Hoveyda
  • Medicated skin care preparation for promoting wound healing
    Patent number: 8128973
    Abstract: Herbal skin care compositions for the promotion of wound healing is provided.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: March 6, 2012
    Inventor: Noreen Mulvanerty
  • Preparation of canola protein isolate and use in aquaculture
    Patent number: 8128965
    Abstract: A canola protein isolate useful in aquaculture is formed by a procedure in which canola oil seed meal is extracted to cause solubilization of protein in the canola oil seed meal to form an aqueous protein solution having a protein content of about 5 to about 40 g/L and a pH of about 5 to about 6.8. After separation of the aqueous protein solution from the residual canola oil seed meal, the protein concentration is increased to at least about 50 g/L while maintaining the ionic strength substantially constant by using a selective membrane technique. The concentrated protein solution is dried to provide a canola protein isolate having a protein content of at least about 90 wt % (N×6.25) d.b.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: March 6, 2012
    Assignee: Burcon Nutrascience (MB) Corp.
    Inventors: Martin Schweizer, Brent E. Green, Randy Willardsen
  • Bardet-Biedl susceptibility gene and uses thereof
    Patent number: 8129161
    Abstract: The present invention relates to the identification of a gene, now designated negevin (ngvn), that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. The human NGVN protein disclosed herein is 731 amino acids in length and is coded for by a gene spanning 17 exons. Homologs have been identified in mouse, rat, zebrafish. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: March 6, 2012
    Assignee: The University of Iowa Research Foundation
    Inventors: Val Sheffield, Darryl Nishimura, Edwin Stone
  • Compositions and methods for treating infestations
    Patent number: 8128968
    Abstract: Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: March 6, 2012
    Assignee: Tissuetech, Inc.
    Inventors: Ying-Ying Gao, Scheffer C. G. Tseng
  • Treatment of diabetes
    Patent number: 8124582
    Abstract: The present invention relates to methods and compounds for regulating glucose metabolism, achieving glucose homeostasis, and decreasing blood glucose levels. Methods and compounds for treating or preventing diabetes, hyperglycemia, and disorders and conditions associated with altered or impaired glucose metabolism are also provided.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: February 28, 2012
    Assignee: FibroGen, Inc.
    Inventors: Volkmar Guenzler-Pukall, Stephen J. Klaus, Ingrid Langsetmo Parobok, Todd W. Seeley
  • Stabilized preparations of serine endopeptidases, their preparation and use
    Patent number: 8124737
    Abstract: The invention relates to stabilized preparations of serine endopeptidases which are suitable for use as a test reagent in a diagnostic procedure or for a therapeutic use. As a result of the addition of various additives, the preparations have improved stability and shelf life.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: February 28, 2012
    Assignee: Seimens Healthcare Diagnostics Products GmbH
    Inventors: Andrea Lichte, Verena Kräling
  • Cranberry seed oil, cranberry seed flour and a method for making
    Patent number: 8124142
    Abstract: The present invention includes a cranberry seed oil, a cranberry flour and a method for making cranberry seed oil and flour. The cranberry seed oil comprises beta sitosterol and phosphatidylcholine.
    Type: Grant
    Filed: March 5, 2004
    Date of Patent: February 28, 2012
    Inventors: Tim Heeg, Bernard G. Lager, II
  • Cinnamomi and poria composition, method to prepare same and uses thereof
    Patent number: 8119141
    Abstract: This invention provides a method for identifying a composition of Cinnamomi and Poria. This invention further provides a composition comprising: Ramulus Cinnamomi, Poria Cortex, Moutan Radicis, Radix Paeonize Alba, and Semen Persicae. This invention provides various uses of these compositions.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: February 21, 2012
    Assignee: Jiangsu Kanion Pharmaceutical Co. Ltd.
    Inventor: Wei Xiao
  • Infant nutritional compositions for preventing obesity
    Patent number: 8119142
    Abstract: The present invention relates to a method for preventing obesity later in life by administering a certain nutritional composition to an infant with the age between 0 and 36 months. The composition comprises linoleic and alpha-linolenic acid.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: February 21, 2012
    Assignee: N.V. Nutricia
    Inventors: Renate Maria Louise Zwijsen, Gelske Speelmans, Eline Marleen van der Beek, Günther Boehm
  • Administration of HCV protease inhibitors in combination with food to improve bioavailability
    Patent number: 8119602
    Abstract: Methods of treating, preventing or ameliorating one or more symptoms of hepatitis C in a subject comprising the step of administering at least one HCV protease inhibitor in combination with food are provided. Also provided are methods of increasing bioavailability of an HCV protease inhibitor and methods of increasing serum levels of an HCV protease inhibitor in a subject. All methods comprise adminstering at least one HCV protease inhibitor in combination with food, the at least one HCV protease inhibitor selected from the group consisting of compounds of Formulae I-XXVI, described herein. Administration of compounds of the present invention in combination with food provides improved bioavailability and increased peak serum levels of the compounds as compared to administration without food.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: February 21, 2012
    Assignee: Schering Corporation
    Inventors: Jenny Zhang, Samir K. Gupta
  • Methods and compositions for regenerating articular cartilage
    Patent number: 8119591
    Abstract: Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: February 21, 2012
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Mislav Jelic