Patents Examined by David E Smith
  • Patent number: 11908673
    Abstract: An ion molecule reactor for generating analyte ions from analytes comprises: a) a reaction volume in which reagent ions can interact with the analytes in order to form analyte ions; b) at least one analyte inlet for introducing the analytes along an inlet path into the reaction volume whereby, preferably, the inlet path runs essentially along at least a first section of the predefined transit path in the reaction volume; c) at least one reagent ion source and/or at least one reagent ion inlet for providing reagent ions into the reaction volume; d) optionally, at least one ion guide comprising an electrode arrangement which is configured for producing an alternating electrical, magnetic and/or electromagnetic field, that allows for guiding the reagent ions and/or the analyte ions at least along a section of the predefined transit path, preferably along the whole transit path, through the reaction volume.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: February 20, 2024
    Assignee: TOFWERK AG
    Inventors: Felipe Lopez-Hilfiker, Manuel Hutterli, Marc Gonin, Carsten Stoermer, Michael Kamrath
  • Patent number: 11890490
    Abstract: A quality assurance device for a medical accelerator includes a housing having an inner radioluminescent layer adapted to provide a visual indication when contacted with invisible radiation generated by the medical accelerator. In addition, the quality assurance device includes one or more passive optical components within the housing adapted to deliver an image of the inner radioluminescent layer of the housing including the visual indication to one or more cameras located outside of the housing.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: February 6, 2024
    Assignee: University of Kentucky Research Foundation
    Inventors: Janelle A. Molloy, Dennis A. Cheek, Quan Chen
  • Patent number: 11890387
    Abstract: A germicidal system for use in disinfecting a human interface device includes at least one human interface device. One or more ultra-violet (UV) light sources are used in proximity to the at least one human interface device for disinfecting a touch surface of the human interface device below a surgical grade sterilization. A memory for storing usage data of the at least one UV light source. At least one server is used for providing a central storage location for usage data supplied from the memory and a computer is used in communication with the at least one server for controlling the operational parameters of the at least one UV light source.
    Type: Grant
    Filed: September 22, 2022
    Date of Patent: February 6, 2024
    Assignee: UV Partners, Inc.
    Inventor: Theodore John Cole
  • Patent number: 11887807
    Abstract: A multi-beam apparatus for observing a sample with high resolution and high throughput is proposed. In the apparatus, a source-conversion unit forms plural and parallel images of one single electron source by deflecting plural beamlets of a parallel primary-electron beam therefrom, and one objective lens focuses the plural deflected beamlets onto a sample surface and forms plural probe spots thereon. A movable condenser lens is used to collimate the primary-electron beam and vary the currents of the plural probe spots, a pre-beamlet-forming means weakens the Coulomb effect of the primary-electron beam, and the source-conversion unit minimizes the sizes of the plural probe spots by minimizing and compensating the off-axis aberrations of the objective lens and condenser lens.
    Type: Grant
    Filed: January 23, 2023
    Date of Patent: January 30, 2024
    Assignee: ASML Netherlands B.V.
    Inventors: Weiming Ren, Xuedong Liu, Xuerang Hu, Zhongwei Chen
  • Patent number: 11887743
    Abstract: Conformal coatings provide environmental protection for sensitive military electronics. Preliminary MCNP™ modeling of metal oxide impregnated acrylic conformal coatings indicates an effective shield for gammas below 10 keV and a reduction in neutron displacement damage to Si-based electronics across the Watt spectrum. This work provides data which can allow an optimal overall shielding worth per total weight to eventually be evaluated.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: January 30, 2024
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Robert Bruce Hayes, Michael Jeffrey DeVanzo
  • Patent number: 11887831
    Abstract: In some embodiments, a method for optimizing performance of a mass spectrometer comprises using an ion source to generate ions, collisionally cooling the ions within an ion guide, directing said ions from the ion guide through at least one ion lens to a downstream mass analyzer, ramping a DC voltage applied to the ion lens, performing a mass analysis of the ions within the mass analyzer while the DC voltage applied to the ion lens is ramped, estimating performance of the mass spectrometer by measuring one or more characteristics of at least one of an ion signal and the voltage ramp, and adjusting a DC voltage applied to said at least one lens element based on said measured one or more characteristics of at least one of the ion signal and the voltage ramp so as to enhance performance of the mass spectrometer.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: January 30, 2024
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Leigh Bedford, Yang Kang, Yves Le Blanc, Bradley Schneider
  • Patent number: 11881378
    Abstract: Provided herein are approaches for angle control of neutral reactive species ion beams. In one approach, a workpiece processing apparatus may include a plasma source operable to generate a plasma within a plasma chamber enclosed by a chamber housing, and an extraction plate coupled to the chamber housing. The extraction plate may include a plurality of channels for delivering one or more radical beams to a workpiece, wherein each of the plurality of channels has a lengthwise axis oriented at a non-zero angle relative to a perpendicular extending from a main surface of the workpiece, wherein each channel of the plurality of channels has a channel length and a channel width, and wherein the channel width varies along the channel length.
    Type: Grant
    Filed: May 13, 2022
    Date of Patent: January 23, 2024
    Inventors: Glen F. R. Gilchrist, Yufeng Qiu
  • Patent number: 11879470
    Abstract: A mass spectrometer comprising: a vacuum housing comprising a first vacuum chamber having a first gas exhaust port; a gas pump (1700) having a first gas inlet port connected to the first gas exhaust port (H1) by a first gas conduit for evacuating the first vacuum chamber; and a first apertured cover (2010) arranged over the first gas exhaust port (H1) or first gas inlet port, or in the first gas conduit therebetween.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: January 23, 2024
    Assignee: Micromass UK Limited
    Inventors: Cedric Marsh, Peter Carney, Jason Lee Wildgoose, David Wallis, Paul McIver, Soji Chummar, George Andreas Antoniades, Dipesh Mistry
  • Patent number: 11879784
    Abstract: The invention relates to a modulatable infrared emitter comprising a MEMS heating element and an actuator, wherein the actuator triggers shape and/or structure changes of the MEMS heating element. Said change in shape and/or structure of the MEMS heating element may vary the ratio of the emitting area to the total area, thereby producing a change in intensity of the emitted infrared beam. The invention further relates to a manufacturing method for the infrared emitter, a method for modulated emission of infrared radiation using the infrared emitter, and preferred uses of the infrared emitter. In further preferred aspects the invention relates to a system comprising the infrared emitter and a control device for regulating the actuator.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: January 23, 2024
    Assignee: Hahn-Schickard-Gesellschaft für angewandte Forschung e. V.
    Inventors: Alfons Dehé, Achim Bittner, Daniel Biesinger
  • Patent number: 11879897
    Abstract: Real-time search (RTS) for mass spectrometry is described. In one aspect, a mass spectrometer can identify a candidate peptide for a product ion spectrum by searching a mass spectral database. While executing the search of the mass spectral database, the elapsed search time can be monitored. If the elapsed search time of the identification of the candidate peptide is completed before reaching a maximum value, then the mass spectrometer can perform further actions.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: January 23, 2024
    Assignee: Thermo Finnigan LLC
    Inventor: Derek J. Bailey
  • Patent number: 11881376
    Abstract: Described are ion implantation devices, systems, and methods, and in particular to an ion source that is useful for generating an aluminum ion beam.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: January 23, 2024
    Assignee: ENTEGRIS, INC.
    Inventors: Ying Tang, Joe R. Despres, Joseph D. Sweeney, Oleg Byl, Barry Lewis Chambers
  • Patent number: 11881388
    Abstract: Methods and systems for FTMS-based analysis having an improved duty cycle relative to conventional FTMS techniques are provided herein. In various aspects, the methods and systems described herein operate on a continuous ion beam, thereby eliminating the relatively long duration trapping and cooling steps associated with Penning traps or orbitraps of conventional FTMS systems, as well as provide increased resolving power by sequentially interrogating the continuous ion beam under different radially-confining field conditions.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: January 23, 2024
    Assignee: DH Technologies Development Pte. Ltd.
    Inventor: James W Hager
  • Patent number: 11875985
    Abstract: A mass spectrometer includes an ion trap, which has an interior for storing ions, a signal generator, which is connected to an electrode of the ion trap, which delimits the interior, for coupling in a voltage signal, in particular a radiofrequency voltage signal, and an ionization device for ionizing a gas to be ionized and supplied to the interior. The ionization device is connected to the signal generator in order to use the voltage signal (URF, UStim1, Ustim2) of the signal generator, which is coupled into the electrode, for generating ions.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: January 16, 2024
    Assignee: Leybold GmbH
    Inventors: Leonid Gorkhover, Gennady Fedosenko, Alexander Laue, Rudiger Reuter, Hin Yiu Anthony Chung
  • Patent number: 11875981
    Abstract: A method of operating a mass spectrometer that allows for high-speed operation is disclosed. The method consists in separating the various steps needed to produce a mass spectrum into three or more conceptual stages in a pipeline, such that the instrument is performing steps to process more than two precursor-ion species simultaneously. In general, the number of stages in the pipeline should at least one more and, preferably, at least two more than the number of buffering storage devices in the instrument. The presently-taught methods and apparatus allow for nearly 100% duty cycle of ion accumulation for precursors of interest.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: January 16, 2024
    Assignee: THERMO FINNIGAN LLC
    Inventors: Michael W. Senko, Philip M. Remes
  • Patent number: 11869746
    Abstract: In one embodiment, a multi-beam writing method is for irradiating each of pixels defined on a substrate, placed on a stage, with each beam of a multi-beam to form a pattern. The method includes obtaining a position correction amount of the pattern by each of a plurality of sub-arrays into which an array of the multi-beam is divided at least in a predetermined direction, based on the positional deviation amount of each beam of each of the sub-arrays, which obtained by dividing an array of the multi-beam at least in the predetermined direction, calculating an dose of the each beam irradiated to each pixel for shifting the position of the pattern drawn for each of the sub-arrays based on the position correction, and performing multi-writing using at least a portion of each two or more of the sub-arrays with the calculated dose.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: January 9, 2024
    Assignee: NuFlare Technology, Inc.
    Inventors: Hiroshi Matsumoto, Yasuo Kato
  • Patent number: 11869678
    Abstract: Examples include a method to position atoms. The method comprises considering a target Hamiltonian encoding a specific problem to resolve using an optical tweezer traps quantum computing system. The method also comprises considering a set of representative Hamiltonians function of a position configuration of atoms in the quantum computing system. The method further comprises determining a specific position configuration whereby a specific similarity measure between the target Hamiltonian and a specific Hamiltonian of the representative Hamiltonians function of the specific position configuration is improved compared to another similarity measure between the target Hamiltonian and at least one other representative Hamiltonian function of a position configuration differing from the specific position configuration.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: January 9, 2024
    Assignee: BULL SAS
    Inventor: Bertrand Marchand
  • Patent number: 11867684
    Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: January 9, 2024
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, He Wang, Nicholas E. Manicke, Robert Graham Cooks, Qian Yang, Jiangjiang Liu
  • Patent number: 11867852
    Abstract: Embodiments herein describe an atomic sensor that includes a photonic die that outputs optical signals on a top surface. These optical signals can be directed and shaped as needed to satisfy a particular type of atomic sensor. In one embodiment, an atomic source (e.g., rubidium or cesium) is disposed on the photonic chip to emit atoms when heated. A collimator can then direct the emitted atoms along a path that intersects with the optical signals. This intersection can be used to detect motion (e.g., rotation and acceleration) of the atomic sensor.
    Type: Grant
    Filed: June 23, 2023
    Date of Patent: January 9, 2024
    Assignee: Vector Atomic, Inc.
    Inventors: Matthew Todd Cashen, Martin Machai Boyd, Christopher Scott Corder
  • Patent number: 11867700
    Abstract: The present disclosure relates to methods of identifying components present in intact lipoprotein particles. Methods provided include single particle mass spectrometry, such as charge detection mass spectrometry (CDMS). Distinct subtypes and subpopulations that exist within lipoprotein density classes are determined based on simultaneously measured m/z and charge of ionized lipoprotein particles.
    Type: Grant
    Filed: April 11, 2023
    Date of Patent: January 9, 2024
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: Martin F. Jarrold, Corrine A. Lutomski
  • Patent number: 11869759
    Abstract: After performing an analysis on a standard sample for a predetermined time, a plurality of ion optical elements such as an ion guide are sequentially selected one by one, and a direct-current voltage having a polarity different from that at the time of analysis is temporarily applied. Meanwhile, intensity data of ions having a specific m/z are continuously collected. After thus collecting the data, the ratio of the ion intensities before and after application of direct-current voltages having different polarities is calculated for each ion optical element, and it is determined whether or not the ratio is equal to or larger than a predetermined threshold value.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: January 9, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Manabu Ueda