Abstract: A renal therapy apparatus includes a blood filter, a blood pump, a treatment fluid pump, and a control unit configured to control at least one of the blood pump or the treatment fluid pump during a filter cleaning sequence. The blood filter includes a plurality of hollow fiber membranes. During the filter cleaning sequence, a fluid mixture is formed by mixing air with a blood-compatible and physiologically safe fluid. Also during the filter cleaning sequence, the fluid mixture is transferred across insides and/or outsides of the plurality of hollow fiber membranes at least one time. The use of the fluid mixture enables the filter cleaning sequence to be performed during the blood treatment.

Abstract: A blood purification apparatus with a blood circuit that allows a patient's blood to extracorporeally circulate and a blood purifier connected to the blood circuit and that purifies the blood in extracorporeal circulation are attachable, the blood purification apparatus including a dialysate introduction line through which dialysate is introduced into the blood purifier; a dialysate drain line through which waste dialysate resulting from blood purification performed by the blood purifier is drained from the blood purifier; and a concentration-detecting unit that detects a concentration of a predetermined substance in the waste dialysate flowing through the dialysate drain line.

Abstract: An extracorporeal blood treatment apparatus comprises a blood treatment device (2), an extracorporeal blood circuit, a blood pump (8) configured to be coupled to a blood withdrawal line (6) of the extracorporeal blood circuit. A closed fluid line (10) is connected to an inlet port (4a) and to an outlet port (4b) of a fluid chamber (4) of the blood treatment device (2), wherein the closed fluid line (10) together with the fluid chamber (4) forms a recirculation loop. An evacuation line (15) departs from the closed fluid line (10). A warming device (13) and a recirculation pump (17) are coupled or configured to be coupled to the closed fluid line (10). At least one temperature sensor (22) is operative on the extracorporeal blood circuit and it is configured to sense a blood temperature (Tb).

Abstract: The invention relates to a circuit arrangement for a protective-conductor connection to at least two fluid-conducting lines 11, 12, in particular to at least two fluid-conducting lines which are guided outwards from the interior of a housing 1 of a medico-technical device, in particular the housing of a blood treatment device. The circuit arrangement comprises a plurality of protection apparatuses 16A, 16B; 17A, 17B for electrical contacting which are designed such that an electrical connection to a fluid in the line can be produced using each protection apparatus for electrical contacting. In the circuit arrangement, at least two protection apparatuses 16A, 16B; 17A, 17B for electrical contacting are assigned to each fluid-conducting line 11, 12. As a result, two protective measures are taken for each fluid-conducting line.

Abstract: There is provided a blood purification apparatus with which the efficiency of dialysate purification can be improved and the reduction in the amount of electrolytes contained in dialysate and necessary for treatment can be suppressed. The blood purification apparatus includes a storage device capable of storing a predetermined amount of dialysate that is necessary for blood purification treatment, a dialysate circulation line through which the dialysate is allowed to circulate by introducing the dialysate in the storage device into the dialyzer and draining waste liquid from the dialyzer into the storage device, and the dialysate purification device that purifies the dialysate in the dialysate circulation line. A treatment state in which the dialysate is allowed to be introduced into the dialyzer without flowing through the dialysate purification device and a purification state in which the dialysate is allowed to be purified by the dialysate purification device are taken switchably.

Abstract: An assembly and a method for treating raw water wherein the raw water is heated on the heating side of a heat pump and at least partially evaporated into an air stream. At least part of the raw water evaporated into the air stream is separated in a suitable device. In addition, the heat pump is provided with heat on the cooling side by means of heated raw water that has not been evaporated into the air stream, and the heat pump has a thermal coupling in a coldest section of its cooling side, in order to provide cooling for external applications.

Abstract: A dialysis system may include a dialysis machine (e.g., a peritoneal dialysis machine) having a fluid system for delivering fluid (e.g., dialysate) to a patient. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to determine volume information for a fluid system of a dialysis machine, wherein the volume information may comprise a patient line volume and an accuracy adjustment volume, and to determine a priming volume to prime the fluid system with a fluid based on the volume information. Other embodiments are described.

Abstract: An automated waste water treatment system includes a collection tank constructed to hold waste water, a first flow line connected to the collection tank to output the waste water from the collection tank, an electrocoagulation unit that receives the waste water and outputs the waste water as coagulated waste water to a flow line, a polymer dosage tank to provide a polymer dosage into the flow line where the polymer dosage mixes with the coagulated waste water to produce and output flocculated waste water. A clarifier connected to the flow line receives the flocculated waste water and produces sludge-free waste water and concentrated sludge, a series of filters to output filter-treated water, and an ultrafiltration system that receives filter-treated water and outputs ultrafiltration-treated water to a reverse osmosis system.

Abstract: An extracorporeal circulation apparatus including a blood circuit including an arterial blood circuit and a venous blood circuit whose proximal ends are connected to a blood purifier, the blood circuit allowing a patient's blood to extracorporeally circulate from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a discharge unit through which a priming solution supplied into the blood circuit is discharged to an outside; a negative-pressure-generating unit that generates a negative pressure in a region of the blood circuit, the region being filled with the priming solution; and a control unit that controls the negative-pressure-generating unit.

Abstract: Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Abstract: A portable water conditioning system is provided that includes a water conditioner, a first sensor, a second sensor, and a controller. The water conditioner has a plurality of conditioning stages that condition water. The plurality of conditioning stages include, in a direction of flow of the water through the water conditioner, a reverse osmosis stage and a deionizing stage. The first sensor detects a first condition of the water before the reverse osmosis stage. The second sensor detects a second condition of the water after the reverse osmosis stage. The controller is in communication with the first and second sensors and determines a health status of the reverse osmosis stage based the first and second conditions. The first and second conditions each include a level of total dissolved solids of the water.

Abstract: A filter element (3) is designed as a replacement element and has filter medium (59) formed as a hollow body and extending between two closure parts in the form of end caps (13, 19). The filter medium is pleated with individual filter folds (66), and includes a filter material (61) made of cellulose.

Abstract: The present invention relates to an apparatus for degassing liquids comprising a degassing system, wherein the degassing system has a first degassing chamber, a second degassing chamber, a liquid store, a pump, and a supply line that connects the liquid store to the first degassing chamber; wherein the pump is connected to the first degassing chamber at the intake side and to the second degassing chamber at the pressure side; and wherein the degassing system furthermore has a return line that can be cut off and that connects the two degassing chambers to one another, and wherein the apparatus comprises a controller that is configured to operate the degassing system in a first operating mode and in a second operation mode; wherein the degassing system is connected in the first operation mode such that the pump conducts liquid away from the first degassing chamber and supplies it to a removal unit for degassed liquid; and wherein the degassing system is connected in the second operating mode such that liquid is

Abstract: A method of fabricating an coating includes providing a coating comprising a base material. The base material is coated with an inorganic material using at least one of an atomic layer deposition (ALD), a molecular layer deposition (MLD), or sequential infiltration synthesis (SIS) process. The SIS process includes at least one cycle of exposing the coating to a first metal precursor for a first predetermined time and a first partial pressure. The first metal precursor infiltrates at least a portion of the base material and binds with the base material. The coating is exposed to a second co-reactant precursor for a second predetermined time and a second partial pressure. The second co-reactant precursor reacts with the first metal precursor, thereby forming the inorganic material on the base material. The inorganic material infiltrating at least the portion of the base material. The inorganic material is functionalized with a material.

Abstract: A system for holographic control of a hemodialysis machine according to one embodiment includes a hemodialysis control system of the hemodialysis machine and a holographic system communicatively coupled to the hemodialysis control system.

Abstract: Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Abstract: A manifold assembly and a method of engaging a filter capsule in the manifold assembly are provided.

Abstract: An automated waste water treatment system includes a collection tank constructed to hold waste water, a first flow line connected to the collection tank to output the waste water from the collection tank, an electrocoagulation unit that receives the waste water and outputs the waste water as coagulated waste water, a polymer dosage tank to provide a polymer dosage to the coagulated waste water to produce and output flocculated waste water. An air grid of the electrocoagulation unit, the latter housing a plurality of electrodes, increases the lifespan and efficiency of the electrodes to perform electrocoagulation of the waste water. A clarifier connected to the flow line receives the flocculated waste water and produces sludge-free waste water and concentrated sludge, a series of filters to output filter-treated water, and an ultrafiltration system that receives filter-treated water and outputs ultrafiltration-treated water to a reverse osmosis system.

Abstract: A sprinkler includes a sprinkler head and a handle, the sprinkler head is connected with the handle and is arranged to penetrate through the inside of the handle, a water inlet connected with an external water pipe is formed on a tail portion of the handle, a sprinkling surface is disposed on a front end surface of the sprinkler head, a plurality of water outlets are formed on the sprinkling surface, a first filter screen and a second filter screen are further disposed in the sprinkler head, the first filter screen is close to the water outlets, and a filter material or filter cotton for filtering is disposed between the first filter screen and the second filter screen.

Abstract: A peritoneal dialysis system includes first and second concentrate sources in selective fluid communication with a medical fluid pumping cassette, the first and second concentrate sources holding first and second peritoneal dialysis concentrates, respectively; a pump actuator configured to cause the medical fluid pumping cassette to pump the first and second concentrates; and a processor and memory configured to (i) determine a cumulative volume of at least one of the first or second peritoneal dialysis concentrates pumped from the medical fluid pumping cassette by the pump actuator, (ii) compare the cumulative volume to a threshold, and (iii) if the cumulative volume is outside of the threshold, modify a subsequent stroke volume of at least one of the first or second pump chambers actuated by the pump actuator in an attempt to cause an updated cumulative volume for the at least one peritoneal dialysis concentrate to be within the threshold.