Abstract: An example method is performed by a current defibrillator and includes determining that a memory embedded within a therapy cable coupled to the current defibrillator stores data indicative of a previous shock delivered to a patient, the previous being delivered using a previous defibrillator. The method also includes obtaining the data indicative of the previous shock, and setting an energy level for a subsequent shock based on the data indicative of the previous shock. The method further includes delivering the subsequent shock to the patient at the energy level for the subsequent shock.

Abstract: Seals used within lead bores of implantable medical devices for creating a seal to implantable medical leads inserted into the lead bores include a cylinder that engages the lead body. The length of contact of the cylinder to the lead body is at least 0.010? long while average contact pressure is no greater than (10 pounds per inch)/(contact length). Adequate electrical isolation is achieved, even when a debris particle is present between the inner cylinder and the lead body while insertion force remains acceptable.

Abstract: Improved devices, circuits and methods of operation in implantable stimulus systems. An implantable defibrillator may comprise a charging circuit using a transformer to store and build up energy on an HV capacitor or capacitor stack, with the HV capacitor in turn coupled to an H-bridge output circuit having low and high sides for issuing therapy. In the output current path, a current controlling circuitry is placed between the H-bridge and ground, allowing the greater flexibility in the selection of switching devices, and drivers for such devices, in the H-bridge circuit and/or enabling circuits between the H-bridge and the HV capacitor or other therapy circuit.

Abstract: Systems, methods, and other techniques for monitoring, including non-invasive monitoring, of biological markers based on the interaction, temporal association, or coincidence of brain activity and periphery activity in a mammal are provided. Systems and methods for generating a behavioral state-independent representation of cardiac activity and for identifying cardiac events and/or brain-periphery, e.g., brain-cardiac, temporal associations useful as biomarkers of disease such as, e.g., neurologic disease, in a mammal are also provided.

Abstract: A Medical Device Application (MDA) is disclosed for an external device (e.g., a cell phone) that can communicate with an Implantable Medical Device (IMD). The MDA receives data logged in the IMD, processes that data in manners reviewable by an IMD patient, and that can control the IMD based on such processed data. The MDA can use the logged data to adjust IMD therapy based on patient activity or posture, and allows a patient to learn optimal therapy settings for particular activities. The MDA can also use the logged data to allow a patient to review details about IMD battery performance, whether such battery is primary or rechargeable, and to control stimulation parameters based on that performance. The MDA also allows a patient to enter medicine dose information, to review the relationship between medicinal therapy and IMD therapy, and to adjust IMD therapy based on the dosing information.

Abstract: In certain embodiments, a system for aligning an eye with a patient interface of a laser device includes a camera, a display screen, and a computer. The camera records images of the eye through the patient interface of the laser device. A liquid is disposed between and is in contact with the patient interface and the outer surface of the eye. The images include an outline of the liquid. The display screen displays the images of the eye. The computer aligns the eye with the patient interface by: identifying the outline of the liquid in an image received from the camera; determining a misalignment of the eye according to the outline; and instructing the display screen to display a description of the misalignment.

Abstract: Improved devices, circuits and methods of operation in implantable stimulus systems. An implantable defibrillator may comprise an H-bridge output circuit having low and high sides, with a current controlling circuit coupled to the high side of the H-bridge output circuit and a current monitoring circuit coupled to the low side of the H-bridge output circuit. A bootstrap design or a DC isolating circuit or circuit element may be used in the current controlling circuit.

Abstract: In one embodiment, a method to alert a user of a wearable cardioverter defibrillator (WCD) is described. The method includes detecting a condition requiring attention of the patient and issuing an alert to notify the patient of the condition. The method also includes receiving a first input from the patient to replay the audible portion of the alert and replaying the audible portion of the alert when the first input is received.

Abstract: A patient-coupled resuscitation device for use with a plurality of medical devices is provided. The resuscitation device includes a portion configured to provide treatment, a connector configured to connect the resuscitation device to one of a first medical device and a second medical device, and a housing including a memory and associated circuitry. The memory and associated circuitry is configured to store a device identifier to identify the resuscitation device; receive medical treatment information from the first medical device, the medical treatment information including at least one of: patient physiological data, patient characteristic data, and rescuer performance data; receive timing information of the medical treatment information from the first medical device; record the medical treatment information and the timing information; and transfer, upon detecting a connection to the second medical device, the medical treatment information and the timing information to the second medical device.

Abstract: A group select matrix is added to an implantable stimulator device to allow current sources to be dedicated to particular groups of electrodes at a given time. The group select matrix can time multiplex the current sources to the different groups of electrodes to allow therapy pulses to be delivered at the various groups of electrodes in an interleaved fashion. Each of the groups of electrodes may be confined to a particular electrode array implantable at a particular non-overlapping location in a patient's body. A switch matrix can be used in conjunction with the group select matrix to provide further flexibility to couple the current sources to any of the electrodes.

Abstract: An exemplary electrode lead includes a flexible body formed of a flexible insulating material, an electrode contact disposed on a side of the flexible body, a coiled electrode wire provided within the flexible body so as to extend along a length of the flexible body and electrically connect the electrode contact to a signal source, and a coiled reinforcing element provided within the flexible body so as to extend together with the coiled electrode wire along the length of the flexible body. A winding direction of the coiled electrode wire is opposite a winding direction of the coiled reinforcing element and a winding pitch of the coiled electrode wire is smaller than a winding pitch of the coiled reinforcing element. Corresponding methods of manufacturing an electrode lead are also described.

Abstract: Disclosed are devices and methods for non-invasively measuring arterial stiffness using pulse wave analysis of photoplethysmogram data. In some implementations, wearable biometric monitoring devices provided herein for measuring arterial stiffness have the ability to automatically and intelligently obtain PPG data under suitable conditions while the user is engaged in activities or exercises. In some implementations, wearable biometric monitoring devices are provided herein with the ability to remove PPG data variance caused by factors unrelated to arterial stiffness. In some implementations, wearable biometric monitoring devices have the ability to perform PWA while accounting for the user's activities, conditions, or status.

Abstract: Provided are a defibrillation catheter system, a defibrillation power supply device, and a method for controlling the device during observation of intracardiac potential and defibrillation. A defibrillation catheter system 1 includes a catheter 20; a first power supply part 6A and a second power supply part 6B connected to the catheter 20; and an electrocardiograph 40 measuring an intracardiac potential, wherein the catheter 20 is provided with a first electrode group 21 having at least a 1-1 electrode and a 1-2 electrode and a second electrode group 22 having at least a 2-1 electrode and a 2-2 electrode, the first and second electrode groups 21 and 22 are connected to the electrocardiograph 40, the 1-1 electrode and the 2-1 electrode are connected to the first power supply part 6A, and the 1-2 electrode and the 2-2 electrode are connected to the second power supply part 6B.

Abstract: The electrical stimulation belt includes an electrical stimulator, a flexible substrate, a plurality of electrical connectors, a plurality of electrodes and a plurality of locators. The electrical stimulation is applied to the trunk or waist of a patient by the electrical stimulator belt through the placement of the plurality of electrical connectors in contact with the plurality of electrodes on the belt. A plurality of locators releasably fastened to the belt assist the user in locating the electrodes on the belt.

Abstract: Apparatus is provided that includes a retinal stimulator, which includes an electrode array including electrodes, which are configured to be coupled to a retina of a subject's eye; and driving circuitry, configured to drive the electrodes to apply currents to the retina. The retinal stimulator further includes an elastic anchor that is coupled to the retinal stimulator and is configured to anchor the electrodes to the retina without the elastic anchor penetrating the retina. Other embodiments are also described.

Abstract: A headset for positioning an electronic device against a head of a patient includes a flexible frame configured to surround a portion of the head, the flexible frame defining an interior channel and an exterior slot, a curved structure configured to grasp an ear of the patient, the curved structure being movable within the interior channel of the flexible frame for accommodating a size of the head, and a mount including a support base to which the electronic device can be attached, the mount being slidable along the exterior slot of the flexible frame to position the electronic device along the head.

Abstract: The disclosure describes example devices, systems, and techniques for delivering electrical stimulation to a patient. In some examples, an IMD includes a housing having a main portion and projection extending from the main portion. The projection of the housing may carry an electrode. Stimulation circuitry may be disposed within the main portion of the housing where the stimulation circuitry may generate electrical stimulation deliverable via the electrode. Processing circuitry may be disposed within the main portion of the housing where the processing circuitry may control the stimulation circuitry to generate the electrical stimulation.

Abstract: Provided are a defibrillation catheter system, a defibrillation power supply device, and a method for controlling the device during observation of intracardiac potential and defibrillation. A defibrillation catheter system 1 includes a catheter 20; a power supply part 6 connected to the catheter 20; an electrocardiograph 40 measuring an intracardiac potential; a first electrode 21 and a second electrode 22 provided on the catheter; and a changeover part 7 connected to the power supply part 6, the changeover part 7 switching between a first mode for measuring the intracardiac potential and a second mode for applying the voltage while the intracardiac potential is measured, wherein the first electrode 21 and the second electrode 22 are connected to the power supply part 6 through the changeover part 7, and the first electrode 21 and the second electrode 22 are connected to the electrocardiograph 40.

Abstract: Systems, methods, and devices to facilitate insertion of certain leads with electrode(s) into patients are described. Leads can be implanted to work in conjunction with a cardiac pacemaker or cardiac defibrillator. A lead for cardiac therapy may be inserted into an intercostal space associated with the cardiac notch of a patient. Devices for delivery may include, for example, a delivery system coupled with an electrical lead and having a handle, a component advancer and insertion tips. The handle is configured to be actuated by an operator and the component advancer is configured to advance an electrical lead into the patient. The insertion tips can be configured to close around the electrical lead within the component advancer, to push through biological tissue, and to open to enable the lead to advance into the patient. The electrical lead can also be maintained in a particular orientation during the advancement into the patient.

Abstract: Systems, apparatus, and methods for treating medication refractory epilepsy are disclosed. In one embodiment, a method of treating epilepsy is disclosed comprising detecting, using a first electrode array coupled to a first endovascular carrier, an electrophysiological signal of a subject. The method further comprises analyzing the electrophysiological signal using a neuromodulation unit electrically coupled to the first electrode array and stimulating an intracorporeal target of the subject using a second electrode array coupled to a second endovascular carrier implanted within a part of a bodily vessel superior to a base of the skull of the subject.