Abstract: A apparatus for estimating concentration may include: a spectrum obtainer configured to obtain Raman spectra of an object; and a processor configured to extract, from the Raman spectra, at least one analyte spectrum related to an analyte and at least one non-analyte spectrum related to a biological component other than the analyte, and estimate concentration of the analyte based on a first area under a curve of the at least one analyte spectrum and a second area under a curve of the at least one non-analyte spectrum.

Abstract: An optical probe comprises three optical elements including at least one light source and at least one light detector. The three optical elements are positioned in a triangular configuration. Three optical fibers are each coupled to one of the three optical elements and have an exposed distal end portion. At least one light shroud is disposed radially around the exposed distal end portions of at least one of the optical fibers coupled to the at least one light source.

Abstract: A sensor connector apparatus is disclosed to connected between an electroencephalographic spectrum analyzer and a sensor for use in the electroencephalographic spectrum analyzer. The sensor connector apparatus includes sensor connectors. Each of the sensor connectors includes: a connector to be connected to the electroencephalographic spectrum analyzer; a connector lead where the connector is connected to one end of the connector lead; and a conductive connector electrode that is connected to another end of the connector lead, and is connected to a sensor electrode of the sensor. The electroencephalographic spectrum analyzer is a bispectral index (BIS) processor, the sensor is a BIS Quatro sensor to be connected to the BIS processor, and the connector is connected to a sensor electrode of the BIS Quatro sensor.

Abstract: An apparatus for non-invasively estimating a biological component is provided. The apparatus may include: a sensor configured to measure a calibration spectrum for a first duration and measure a biological component estimation spectrum for a second duration, based on light returning from an object; and a processor configured to remove a signal of a biological component from the calibration spectrum to obtain a background spectrum for the first duration, and estimate the biological component, based on the background spectrum and the biological component estimation spectrum, for the second duration in response to a command for measuring the biological component.

Abstract: A wearable detection device includes a main body, a first belt body, and a second belt body. The first belt body and the second belt body are connected to two sides of the main body. The main body includes a power source, a control circuit connected to the power source, and a processor connected to the control circuit. The wearable detection device further includes a flexible circuit board and a plurality of to-be-conducted chips. The flexible circuit board is disposed in the first belt body and is connected to the main body. The plurality of to-be-conducted chips are disposed in the first belt body and are connected to the flexible circuit board. When the first belt body and the second belt body are interconnected, the to-be-conducted chip positioned at a junction point is connected.

Abstract: According to one embodiment of the present disclosure, a biometric sensor includes a flexible substrate, a first light-emitting part disposed on one side of the flexible substrate to output first light toward the body, a second light-emitting part disposed on one side of the flexible substrate to output second light different from the first light toward the body, an elastomer disposed on one side of the flexible substrate in a shape surrounding the first light-emitting part and the second light-emitting part, and a light-receiving part disposed on the other side of the flexible substrate to receive third light corresponding to the first light and fourth light corresponding to the second light.

Abstract: A biological component measuring apparatus may include: a first light source configured to emit a first light of a first wavelength range onto an object; a second light source configured to emit a second light of a second wavelength range onto the object, the second wavelength range being different from the first wavelength range; a detector configured to detect the first light and the second light which are scattered from the object; and a processor configured to determine a scattering coefficient based on the detected first light, obtain blood vessel depth information based on the detected second light, and measure a biological component by correcting the scattering coefficient based on the blood vessel depth information.

Abstract: A photoplethysmography (PPG) device includes an equipment module which includes a photodetector and first and second light emitting diodes (LED's) adapted to emit light of first and second wavelengths, respectively. The PPG device also includes a mask covering the patient facing extremity of the equipment module so that when the device is applied to a patient the mask is situated between the patient and the patient facing extremity. A processor is adapted to control drive current and/or operating time of the second LED to achieve an elevated localized body tissue temperature of a patient to which the PPG device is applied.

Abstract: Provided is a flexible transcutaneous oxygen partial pressure sensor which may be closely attached to a skin, be used repeatedly for a long time, and have a highly reliable measurement value. The flexible transcutaneous oxygen partial pressure sensor of the present disclosure includes: an oxygen sensing film having one surface in contact with a skin; a light detecting portion including a light emitting portion which is positioned above a surface opposite to the one surface of the oxygen sensing film and includes a micro-light emitting diode (LED (?-LED)), and a light-receiving portion which includes an organic-photodiode (OPD); and a heater portion positioned between the oxygen sensing film and the light detecting portion, and supplying thermal energy to the skin in contact with the oxygen sensing film.

Abstract: A needle member includes: a tubular side wall through which a hollow portion extends in a longitudinal direction. An opening portion connected to the hollow portion extends laterally through the tubular side wall. The tubular side wall comprises a side wall reinforcement portion located at a position opposing the opening portion, wherein the hollow portion is interposed between the opening portion and the side wall reinforcement portion.

Abstract: A patient monitoring system is for a patient, and may include a base and a frame extending upwardly. The patient monitoring system may include a weight sensor carried by the base, a pair of handrails carried by the frame to be grasped by the patient, and a pair of impedance sensors to be attached to the patient while the patient is on the weight sensor. The patient monitoring system may have a controller coupled to the pair of impedance sensors and the weight sensor and configured to sense a lung impedance of the patient, sense a weight of the patient, and determine whether the patient is experiencing CHF based upon the lung impedance and the weight of the patient.

Abstract: An optoelectronic sensor module and a method for producing an optoelectronic sensor module are disclosed. In an embodiment an optoelectronic sensor module includes a first semiconductor transmitter chip configured to emit radiation of a first wavelength, a second semiconductor transmitter chip configured to emit radiation of a second wavelength different from the first wavelength, a semiconductor detector chip configured to detect the radiation of the first and second wavelengths, and a first potting body being opaque to the radiation of the first and the second wavelength, wherein the first potting body directly covers side surfaces of the chips and mechanically connects the chips located in a common plane to one another, wherein a distance between the chips is less than or equal to twice an average diagonal length of the chips, and wherein the sensor module is adapted to rest against a body part to be examined.

Abstract: An apparatus for estimating a concentration of an analyte may include a spectrum acquisition device configured to acquire a first in vivo spectrum of an object, and a processor configured to estimate the concentration of the analyte using the first in vivo spectrum and a concentration estimation model that is generated based on a second in vivo spectrum measured during a timeframe in which the concentration of the analyte in the object is substantially constant, and update the concentration estimation model based on the first in vivo spectrum and the estimated concentration of the analyte.

Abstract: A device for determining muscle condition of a region of tissue. The device comprises an electrical impedance myography (EIM) portable probe bearing an electrode array. The electrode array comprises excitation electrodes used to apply multi-frequency electrical signals to the region of tissue and pickup electrodes that are used to collect electrical signals resulting from the application of the multi-frequency electrical signals to the region of tissue. To improve accuracy and reproducibility of EIM measurements, the electrode array is reconfigurable to select different subsets of excitation and pickup electrodes so that the electrodes are oriented differently with respect to muscle fibers. Additional devices may be associated with the EIM probe to measure such parameters as temperature, moisture content of the region, quality of contact of electrodes of the electrode array with a surface of the region and pressure with which the EIM probe is applied to the region.

Abstract: In an example, a method of detecting cyanide exposure of an individual comprises measuring a thiocyanate level of the individual, and comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of cyanide poisoning requiring immediate medical assessment.

Abstract: A method for detecting cardiac arrhythmia based on a photoplethysmographic (PPG) signal is provided. The method includes: receiving a PPG signal and a motion signal corresponding to a motion made by a user; extracting PPG signal segments and motion signal segments corresponding to a time period from the PPG signal and the motion signal, respectively, at every time period; filtering out motion artifact noise in the PPG signal segments according to the PPG signal segments and the motion signal segments, and converting the PPG signal segments and the motion signal segments into PPG spectrum diagrams and motion spectrum diagrams, respectively; obtaining an estimated heart rate according to the PPG spectrum diagrams and the motion spectrum diagrams; and determining whether cardiac arrhythmia is present based on the filtered PPG signal segments and the estimated heart rate.

Abstract: A non-invasive method and apparatus utilizing a single wavelength (800 nm, isobestic) for the instantaneous, reflective, non-pulsatile spatially resolved reflectance system, apparatus and mathematics that allows for the correct determination of critical photo-optical parameters in vivo. Transcutaneous blood constituent (analyte or drug level) measurements can be determined in real-time. The “closed-form” nature of the mathematics with inclusion of other wavelengths (660 nm and 1300 nm) and a non-invasive transmissive array allows for immediate calculation and real-time display of Hematocrit, Hemoglobin, fractional tissue blood volume (Xb), Hematocrit-Independent Oxygen Saturation, fractional tissue water content (Xw) and other pertinent blood/plasma values in a variety of handheld or other like devices.

Abstract: Generally, methods, devices, and systems related to analyte monitoring and data logging are provided—e.g., as related to in vivo analyte monitoring devices and systems. In some aspects, methods, devices, and systems are provided that relate to enable related settings based on an expected use of an in vivo positioned sensor; logging or otherwise recording analyte levels acquired or derived—e.g., sample analyte levels more frequently than they are logged or otherwise recorded in memory; dynamically adjust the data logging frequency; randomly determine times of acquiring or storing analyte levels from the in-vivo positioned analyte sensors; and enable recording related settings when the system is operable.

Abstract: A method and system for monitoring oxygen saturation of a patient are provided. An example system includes a wearable device having a first optical sensor to measure a first red wavelength photoplethysmography (PPG) signal and a first infrared wavelength PPG signal and a second optical sensor to measure a second red wavelength PPG signal and a second infrared wavelength PPG signal. The system further includes a processor configured to determine that conditions for calibration of the first optical sensor are satisfied, determine a first ratio for obtaining the oxygen saturation, a first parameter for modifying the first red wavelength PPG signal, a second parameter for modifying the first infrared wavelength PPG signal, and a second ratio for obtaining the oxygen saturation. The processor is further configured to determine a value of the oxygen saturation and provide a message regarding a health status of the patient.

Abstract: A physiological monitor is provided for determining a physiological parameter of a medical patient with a multi-stage sensor assembly. The monitor includes a signal processor configured to receive a signal indicative of a physiological parameter of a medical patient from a multi-stage sensor assembly. The multi-stage sensor assembly is configured to be attached to the physiological monitor and the medical patient. The monitor of certain embodiments also includes an information element query module configured to obtain calibration information from an information element provided in a plurality of stages of the multi-stage sensor assembly. In some embodiments, the signal processor is configured to determine the physiological parameter of the medical patient based upon said signal and said calibration information.