Patents Examined by Ernst V. Arnold
  • Patent number: 10835642
    Abstract: The present disclosure relates to compositions useful in synthetic bone graft applications. Particularly, the disclosure teaches moldable bone graft compositions, methods of making said compositions, and methods of utilizing the same.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: November 17, 2020
    Assignee: Bioventus, LLC
    Inventors: John E. Brunelle, Russell L. Cook, Duraid S. Antone
  • Patent number: 10835514
    Abstract: Pharmaceutical compositions of muscarinic acetylcholine receptor antagonists suitable for administration via a dry powdered inhaler and methods of using the compositions for treating respiratory disease are provided.
    Type: Grant
    Filed: January 7, 2017
    Date of Patent: November 17, 2020
    Inventors: Meenakshi S. Venkatraman, Xiaoming Zhang, Phillip Haywood
  • Patent number: 10828242
    Abstract: The present invention belongs to the area of body odour modelling. In particular, the developed synthetic compositions of the present invention reconstitute human body odours, especially those arising from axillary perspiration. The use of the compositions herein allows for the evaluation of malodour masking effects of fragrant compositions in the field of personal care or homecare products and cosmetic product development.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: November 10, 2020
    Assignees: Symrise AG, Monell Chemical Senses Center
    Inventors: Marco Singer, Keith McDermott, Marcela Olalde-Castillo, George Preti, Charles Wysocki, Katherine Ashley Prigge
  • Patent number: 10814039
    Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: October 27, 2020
    Inventors: Masaaki Mawatari, Masatsugu Tsukamoto, Iwao Noda
  • Patent number: 10814118
    Abstract: Provided is a transdermal absorption sheet capable of improving strength against impact at the time of puncture. A transdermal absorption sheet includes a sheet portion and a plurality of needle-like protruding portions arranged on a first principal surface of the sheet portion, in which the sheet portion has a center portion which is a region in which the plurality of needle-like protruding portions are formed, and an outer edge portion which is a region from the center portion to an end portion, and a maximum thickness of a thickness portion of the outer edge portion is larger than an average thickness of the center portion.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: October 27, 2020
    Assignee: FUJIFILM Corporation
    Inventor: Satoshi Wakamatsu
  • Patent number: 10806705
    Abstract: The present invention provides a patch comprising a backing and an adhesive layer laminated on one side of the backing, wherein the adhesive layer comprises asenapine or a pharmaceutically acceptable salt thereof, an adhesive base and a low molecular weight amine.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: October 20, 2020
    Inventors: Takashi Yasukochi, Atsushi Sonobe, Satoshi Amano
  • Patent number: 10806825
    Abstract: A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles and a suspending agent comprising hyaluronic acid. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: October 20, 2020
    Assignee: SpineOvations, Inc.
    Inventors: Stuart Young, Neville Alleyne, Nicholas John Manesis
  • Patent number: 10806233
    Abstract: Cationically-charged particulates and compositions containing the cationically-charged particulates for application to keratinous materials are provided. Methods of preparing the cationically-charged particulates are also disclosed. Methods of increasing the cationic charge on particulates are also provided.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: October 20, 2020
    Assignee: ELC Management LLC
    Inventor: Wilson A. Lee
  • Patent number: 10799622
    Abstract: The present disclosure relates to a method of treating or reducing adhesions in the peritoneum of a patient in need thereof. The method includes performing adhesiolysis on one or more adhesions involving the patient's peritoneum and/or one or more tissues or organs in the patient's peritoneal cavity; and administering to the peritoneum or the peritoneal cavity of the patient an effective amount of a composition comprising at least one glutamine source. The glutamine source is selected from one or more of L-glutamine, physiologically acceptable salts of L-glutamine, and dipeptides comprising L-glutamine.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: October 13, 2020
    Assignee: Ade Therapeutics, Inc.
    Inventor: Adebola O. E. Obayan
  • Patent number: 10799460
    Abstract: The present invention relates to a formulation for the controlled release of active ingredients after the passage of the ileo-cecal-valve, comprising one or more active ingredients or one or more active ingredient containing cores (W), enveloped by one or more envelopments (C), which are dissoluble or permeable above an individual defined pH value and are dissoluble or permeable below another individual defined pH value, again enveloped by an envelopment (E), which is dissoluble or permeable above still another individual defined pH value.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: October 13, 2020
    Inventor: Roland Saur-Brosch
  • Patent number: 10786597
    Abstract: The present invention relates to methods for producing biphasic calcium phosphate materials using chemical processing methods including exposure to peroxides. The resulting materials exhibit an osteoinductive needle-like surface morphology and are useful as artificial bone grafts.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: September 29, 2020
    Inventors: Sahil Jalota, Russell Cook
  • Patent number: 10786462
    Abstract: Drug delivery using bio-affecting drugs, particularly with shape changing drug delivery devices. Embodiments are included for depots for delivery of a therapeutic agent that change from an elongated state ex vivo to a coil in vivo where the agent is released.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: September 29, 2020
    Assignee: Incept, LLC
    Inventors: Peter Jarrett, Michael J. McGrath, Timothy S. Jarrett, Rami El-Hayek, Andrew C. Vanslette, Courtney A. Rosales, Charles D. Blizzard, Amarpreet S. Sawhney
  • Patent number: 10786444
    Abstract: Novel drug carriers capable of targeted and/or pH dependent release of biologically active agents into selected pH environments including the gastrointestinal (GI), ophthalmic, urinary, or reproductive tracts. Unexpectedly, carriers including free fatty acids (FFA) are able to deliver biologically active agents to various pH environments. Such targeted delivery is tailorable and useful for active agents that are: (a) injurious to the upper GI tract (esophagus, stomach, and duodenum), (b) acid labile, (c) impermeable/insoluble compounds in GI fluids, (d) susceptible to first pass metabolism, and/or (e) cause stomach irritation, upset, or dyspepsia.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: September 29, 2020
    Assignee: PLx Opco Inc.
    Inventors: Upendra Marathi, Susann Childress, Shaun Gammill, Robert W. Strozier
  • Patent number: 10786452
    Abstract: Described herein is a sugar-depleted fruit or vegetable juice product, wherein said juice product is a fruit or vegetable juice or juice-retaining fruit or vegetable derived matter, wherein said juice product contains at least about 5 g/l gluconic acid and said juice product contains any two or three, of (i) at least about 0.5 g/l Ca2+, (ii) at least about 1 g/l K+, and (iii) at least about 0.1 g/l Mg2+. Also provided are methods of producing the same and the use thereof to assist in maintaining the health and well-being of a subject and in the treatment and prevention of medical ailments, specifically those associated with the over-consumption of glucose and/or sucrose or inappropriate metabolism of glucose, e.g. metabolic syndrome, diabetes mellitus type II, obesity, dyslipidemia, insulin resistance, hypertension and liver steatosis.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: September 29, 2020
    Assignee: NOFIMA AS
    Inventors: Jurgen Schrezenmeir, Svein Halvor Knutsen, Simon Ballance
  • Patent number: 10786916
    Abstract: The disclosure deals with a lubricative skin engaging member with progressive release of lubricating polymer from a water-insoluble matrix containing thermoplastic elastomer compound and maleic anhydride copolymer and lubricating polymer in concentration less than 30%. The disclosure lies in the use of the maleic anhydride in grafted form on polyethylene and the incorporation of water-soluble lubricating polymer in concentration less than 30% in the thermoplastic elastomer compound, leading to a lubricative mixture, and to a skin engaging member, with increased homogeneity and water absorption ability that assist in the lubricating polymer release in a progressive and controllable manner.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: September 29, 2020
    Assignee: BIC VIOLEX S.A.
    Inventors: Amalia Skarmoutsou, Nikolaos Chatzigrigoriou
  • Patent number: 10772871
    Abstract: Aspects of the invention include transdermal delivery devices for delivering dexmedetomine to a subject, where the transdermal delivery devices include a single layer matrix dexmedetomine composition. Transdermal delivery devices according to certain embodiments include dexmedetomidine and a pressure sensitive adhesive provided as a single layer formulation. Also provide are methods of using the subject transdermal delivery devices to deliver dexmedetomidine to a subject, as well as kits containing the transdermal delivery devices.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: September 15, 2020
    Assignee: Teikoku Pharma USA, Inc.
    Inventors: Adchara Pongpeerapat, Amit Jain, Bret Berner, Jianye Wen, Jutaro Shudo
  • Patent number: 10758485
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: September 1, 2020
    Assignee: Anterios, Inc.
    Inventor: Timothy Kotyla
  • Patent number: 10758639
    Abstract: The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.
    Type: Grant
    Filed: September 27, 2015
    Date of Patent: September 1, 2020
    Assignee: Polypid Ltd.
    Inventor: Noam Emanuel
  • Patent number: 10751287
    Abstract: Disclosed in certain embodiments is a solid oral dosage form comprising a plurality of particles, each particle comprising (i) a core comprising an active agent susceptible to abuse and an internal adhesion promoter, wherein the cores are (i) dispersed in a matrix comprising a controlled release material or (ii) coated with a controlled release material. The dosage form can also include an alcohol resistant material.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: August 25, 2020
    Assignee: Purdue Pharma L.P.
    Inventors: Rama Abu Shmeis, Sheetal Muley, Zhixin Zong
  • Patent number: 10751222
    Abstract: The present disclosure is to provide a method for producing polyurethane (PU) nanofibers with significantly improved hydrophilicity by producing water-soluble polymer/PU blend nanofiber by coaxial-electrospinning water-soluble polymer and hydrophobic PU, and, subsequently, dissolving and removing the water-soluble polymer from the blend nanofiber in water.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: August 25, 2020
    Assignee: Kyungpook National University Industry-Academic Cooperation Foundation
    Inventors: Jin Hyun Choi, Woo Jin Kim