Patents Examined by Ernst V. Arnold
  • Patent number: 11559492
    Abstract: The present invention relates to the field of coating pharmaceutical substrates. In particular, the invention relates to methods of coating of pharmaceutical substances, pharmaceutical ingredients or a blend of them. The invention also provides a method of making a pharmaceutical formulation which may be processed into a pharmaceutical dosage form, which utilizes solid pharmaceutical particles and a pharmaceutical formulation obtained by the method. The methods of the invention utilize atomic layer deposition technology. The novel methods allow difficult, moisture sensitive and electrically charged pharmaceutical substrates to be easily processable.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: January 24, 2023
    Assignee: Applied Materials, Inc.
    Inventors: Pekka Hoppu, Tommi Kaariainen, Marja-Leena Kaariainen, Aimo Turunen
  • Patent number: 11547116
    Abstract: Described is an initial liquid composition with at least antimicrobial, antibacterial, and/or anti-viral properties comprising chelated metal oxide particles suspended in a polyol, such that metal oxide particles are homogeneously dispersed in a primarily liquid based polyol carrier so that chelated metal oxide particles form a stable complex suspension that is optionally an alkaline based aqueous silver oxide dispersion. The liquid composition can be subsequently added to any polymer or polymer compound/system where the polymer degrades or melts at a temperature lower than the polyol carrier degradation or boiling temperature. The metal oxide complex may also impart beneficial semi-conductive or conductive as well as permeability and flammability property changes to the polymer (host) system.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: January 10, 2023
    Inventors: William Wingfield, Guerry L Grune, Richard L Mason
  • Patent number: 11541011
    Abstract: A composition in powder form comprising alginic acid or sodium alginate, -pectin and chitosan, wherein the % by weight of the polysaccharides is at least 20% with respect to the total weight of the powder, the process for preparing the powder and its use in the treatment of cutaneous wounds and in the sector of food preservation are described.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: January 3, 2023
    Assignee: MATERIAS S.r.l.
    Inventors: Pasquale Del Gaudio, Rita Patrizia Aquino, Paola Russo, Gianluigi De Falco, Luigi Nicolais
  • Patent number: 11529329
    Abstract: A powdered composition is disclosed, the powdered composition comprising a complex between one or more cannabinoids having at least one phenolic moiety and a basic ion exchange resin. Also, an orally dispensable delivery vehicle, a method of manufacturing the powdered composition, a method of manufacturing the orally dispensable delivery vehicle, composition for use as a medicament, composition for use in a treatment, method of treatment, and use of a basic ion exchange resin as a stabilizing agent are disclosed.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: December 20, 2022
    Assignee: NORDICCAN A/S
    Inventor: Søren Christian Schou
  • Patent number: 11529310
    Abstract: The invention provides a delayed release dosage form and a bolus configured for administration to an animal, wherein the dosage form and the bolus is configured to release a hydrophobic substance to the animal over a period of time. Preferably the hydrophobic substance is a haloform. Also provided is the use of the delayed release dosage form or bolus of the invention to reduce methane production in a ruminant animal. Also provided is the method of manufacturing a bolus of the invention.
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: December 20, 2022
    Assignee: RUMINANT BIOTECH CORP LIMITED
    Inventors: Mark Christopher Lay, Hayden Peter Thomas, Neil Richard Gladden, David Leslie Hayman, Geoffrey Earle Corbett, Prabhat Bhusal
  • Patent number: 11517646
    Abstract: A scaffold for tissue repair or wound dressing comprising: a material layer; a polymer fibre layer; and an adhesive component between the material layer and the polymer fibre layer, wherein the adhesive component comprises material having a lower melting temperature (Tm) than the material layer and the polymer fibre layer.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: December 6, 2022
    Assignee: Oxford University Innovation Limited
    Inventors: Osnat Hakimi, Pierre-Alexis Mouthuy, Nasim Zargar Baboldashti, Andrew Carr
  • Patent number: 11517522
    Abstract: The present invention provides an emulsion composition comprising aprepitant for treatment of emesis. Particularly, the invention is a ready-to-use emulsion compositions comprising aprepitant and medium chain triglycerides for administration by intravenous infusion, wherein the emulsion composition is also free of ethanol. Further, the invention also provides processes of preparing such compositions and their use for the prevention and control of acute and delayed chemotherapy-induced nausea and vomiting, and/or for prevention of postoperative nausea and vomiting.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: December 6, 2022
    Assignee: SOMERSET THERAPEUTICS LLC
    Inventors: Prem Sagar Akasapu, Veerappan Subramanian, Ilango Subramanian
  • Patent number: 11510963
    Abstract: Methods of treating acromegaly in a subject are described herein. Exemplary methods include orally administering to the subject at least once daily at least one dosage form comprising octreotide, wherein the octreotide in each dosage form is 20 mg, and wherein the administering occurs at least 1 hour before a meal or at least 2 hours after a meal.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: November 29, 2022
    Assignee: Amryt Endo, Inc.
    Inventors: Roni Mamluk, Sam Teichman
  • Patent number: 11510893
    Abstract: Stable methocarbamol ready to use compositions for parenteral administration including parenteral infusion are provided. In certain embodiments, the compositions are sterile, isotonic, and particulate-matter-free. Further, the compositions reduce or avoid allergic reactions to latex, reduce or avoid extravasation, and permit administration of methocarbamol to subjects having renal pathology. Methods of manufacture and methods of administration are also provided.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: November 29, 2022
    Assignee: Exela Sterile Medicines LLC
    Inventors: Phanesh B. Koneru, John Maloney
  • Patent number: 11504447
    Abstract: The present invention relates to methods for producing biphasic calcium phosphate materials using chemical processing methods including exposure to peroxides. The resulting materials exhibit an osteoinductive needle-like surface morphology and are useful as artificial bone grafts.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: November 22, 2022
    Assignee: SECADA MEDICAL LLC
    Inventors: Sahil Jalota, Russell Cook
  • Patent number: 11504340
    Abstract: The invention provides methods of making microparticle and nanoparticle ocular implants from a compositions comprising: 99 to 60% (w/w) of a photopolymerizable composition selected from the group of fragments or monomers consisting of polyalkylene glycol diacrylate and polyalkylene glycol dimethacrylate, wherein the photopolymerizable composition has a molecular weight in the range of 100 to 20,000 Dalton; a biodegradable polymer selected from the group consisting of aliphatic polyester-based polyurethanes, polylactides, polycaprolactones, polyorthoesters and mixtures, copolymers, and block copolymers thereof; a photoinitiator; and a therapeutic agent.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: November 22, 2022
    Assignee: THE QUEEN'S UNIVERSITY OF BELFAST
    Inventors: Raghu Raj Singh Thakur, David Jones, Rahul Sonawane
  • Patent number: 11497764
    Abstract: Disclosed herein are fully synthetic polymer-based lung surfactant materials, for the first time, as next generation SRT. In vitro studies on these polymer lung surfactants show that the candidate materials effectively mimic the surface tension controlling properties of currently marketed natural lung surfactants. Further, the polymer lung surfactants have strong protein resistance, which makes this class of materials promising also for potential use in Acute Respiratory Distress Syndrome (ARDS) treatment.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: November 15, 2022
    Assignee: Purdue Research Foundation
    Inventors: You-Yeon Won, Hyun Chang Kim
  • Patent number: 11497831
    Abstract: Methods of bioprinting a bio-ink construct on an internal tissue defect or a chondral defect during a minimally invasive surgery on an individual in need thereof are provided, comprising: visualizing the defect; positioning a bioprinter comprising a printhead within proximity of or in contact with the defect; and ejecting a bio-ink from the printhead onto the defect to form a bio-ink layer, thereby generating a bio-ink construct. Further provided are systems for bioprinting a bio-ink construct on an internal tissue defect during a minimally invasive surgery on an individual in need thereof, comprising a control system, an endoscope, and a bioprinter comprising a printhead.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: November 15, 2022
    Assignee: SCRIPPS HEALTH
    Inventors: Darryl D. D'Lima, Clifford W. Colwell, Jr.
  • Patent number: 11484504
    Abstract: The present invention relates to a method for producing a drug delivery system. The method comprises the steps of screen-printing a base paste, and curing the base paste. Furthermore, the method comprises the steps of screen-printing a first paste separate to the base paste, and curing the first paste.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: November 1, 2022
    Assignees: Laxxon Medical AG, Exentis Knowledge GmbH
    Inventors: Achim Schneeberger, Klaus Kühne, Helmut Kerschbaumer, Srdan Vasic
  • Patent number: 11478447
    Abstract: The invention relates to a solid ?9-THC composition containing ?9-THC and a powder former and having a molar ratio of ?9-THC to powder former to form a flowable ?9-THC powder. The powder former is selected from the group consisting of adenine, aspartame, caffeine, lactose, mannitol, nicotinamide, ?-nicotinamide adenine dinucleotide, pipecolic acid, saccharin, aspartic acid, glutamic acid, glutamine, histidine, leucine, methionine, phenylalanine, proline, serine, tryptophan, valine, Epigallocatechin Gallate (EGCG), 2-Hydroxypropyl-beta-cyclodextrin (HPbCD), and Trimethyl-beta-cyclodextrin (TOMBC) and mixtures thereof. The invention also relates to methods of making a solid ?9-THC composition of the invention. The ?9-THC may be synthetic ?9-THC or may be extracted ?9-THC.
    Type: Grant
    Filed: January 13, 2022
    Date of Patent: October 25, 2022
    Assignee: CANNA CHEMISTRIES LLC
    Inventors: Emily Rigsbee, David T. Jonaitis, Nathan Schultheiss, Lloyd Steven Miller
  • Patent number: 11458159
    Abstract: The present invention refers to an oxygen carrier, preferably hemoglobin or myoglobin, for use in the treatment of an unpleasant feeling of a body surface due to a disease or a disorder.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: October 4, 2022
    Assignee: MÖLNLYCKE HEALTH CARE AB
    Inventor: Michael Sander
  • Patent number: 11452742
    Abstract: The present disclosure relates to pharmaceutical compositions comprising zinc, copper, at least one micronutrient, and a pharmaceutically acceptable excipient; and comprising administering, to a subject in need thereof, a pharmaceutical composition comprising zinc, copper, at least one micronutrient, and a pharmaceutically acceptable excipient.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: September 27, 2022
    Assignees: ZINCUM, INC., WAYNE STATE UNIVERSITY
    Inventors: Ananda S. Prasad, Roy A. Varghese, Kenneth W. Brown, Richard P. Scheckenbach
  • Patent number: 11452796
    Abstract: The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graft material are also provided.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 27, 2022
    Assignee: AlloSource
    Inventors: Reginald Stilwell, Ramasamy Sakthivel, William Maslanik
  • Patent number: 11426333
    Abstract: The present disclosure relates to a solid hair cosmetic composition comprising—based on the total weight of the cosmetic composition—about 30.0 to about 60.0% by weight of at least one polyhydric alcohol, and optionally: about 0.1 to about 15.0% by weight of at least one cationic surfactant, about 0.1 to about 20.0% by weight of at least one saturated or unsaturated, branched or unbranched C8-C30 alcohol and/or a saturated or unsaturated, branched or unbranched C8-C30 carboxylic acid and/or a salt of a saturated or unsaturated, branched or unbranched C8-C30 carboxylic acid, and about 0.1 to about 40.0% by weight of at least one polysaccharide, as well as production and application methods and uses thereof.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: August 30, 2022
    Assignee: HENKEL AG & CO. KGAA
    Inventors: Soeren Scheele, Manuela Mette, Petra Westphal, Thomas Schroeder
  • Patent number: 11413250
    Abstract: Drug delivery using bio-affecting drugs, particularly with shape changing drug delivery devices. Embodiments are included for depots for delivery of a therapeutic agent that change from an elongated state ex vivo to a coil in vivo where the agent is released.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: August 16, 2022
    Assignee: Incept, LLC
    Inventors: Peter Jarrett, Michael J. McGrath, Timothy S. Jarrett, Rami El-Hayek, Andrew C. Vanslette, Courtney A. Rosales, Charles D. Blizzard, Amarpreet S. Sawhney