Patents Examined by Ernst V. Arnold
  • Patent number: 10292912
    Abstract: Described herein, are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride and a pyrophosphate salt. Also described are external personal care compositions comprising the complexes, and uses thereof.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: May 21, 2019
    Assignee: Colgate-Palmolive Company
    Inventors: Daniel Schankel, Shiri Nawrocki, Viktor Dubovoy, Long Pan
  • Patent number: 10292911
    Abstract: Described herein are compositions that include a saline solution and reactive oxygen species. Specifically, the composition may include a saline solution, reactive oxygen species, an emollient, and a pH modifier. Also provided is a gel composition that includes a rheology agent. Also provided are methods of making and using the compositions.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: May 21, 2019
    Assignee: Reoxcyn, LLC
    Inventor: Kurt Richards
  • Patent number: 10285941
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: May 14, 2019
    Assignee: Anterios, Inc.
    Inventor: Timothy Kotyla
  • Patent number: 10285922
    Abstract: An aqueous formulation for topical chemical exfoliation to the skin containing purified water, polyacrylic acid, disodium ethylenediaminetetraacetate, glycerin, specially denatured alcohol, dimethicone, cetyltrimethylammonium chloride, papain enzyme, citrus seed extract, and a nontoxic preservative. The formulation may further contain benzylalcohol and dehydroacetic acid which serve as effective nontoxic preservatives. The exfoliating formulations of the invention are useful in the removal of the surface layer of the skin and in particular, the dead cells of the stratum corneum. The formulation may be retained in an air tight vessel such as a syringe. About 5 rads to about 10 rads of gamma radiation may be applied to the formulation retained within the air tight vessel.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: May 14, 2019
    Inventor: Bruce Wayne Miller
  • Patent number: 10278903
    Abstract: The present invention relates to composite powder having enhanced water repellency and oil absorbency by means of even impregnation of inorganic powder particles with a super-water-repellent porous polymer. The composite powder prepared by means of a one-step spraying procedure of electro-spraying or spray drying, according to the present invention, shows super water repellency and maximized oil absorbency by means of increased porosity of porous polymethyl methacrylate (PMMA) and even impregnation with titanium dioxide (TiO2) nanoparticles.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: May 7, 2019
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Hyun Suk Lee, Yong Jin Kim, Jon Hwan Lee, Se Jun Park, Kyung Ho Choi, Yeong Jin Choi, Sung-Wook Choi, Dong-Hyun Paik
  • Patent number: 10278905
    Abstract: The present invention provides a composition comprising a high load of metal oxides that is phase stable and sprayable. It comprises a branched hydrophobically modified ethoxylated urethane copolymer and a hydrophobically modified alkali swellable emulsion copolymer comprising of one or more acrylate monomers and an ethoxylated associative comonomer.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: May 7, 2019
    Assignee: Johnson and Johnson Consumer Inc.
    Inventors: David Scott Byren, Michael J. Fevola, Jessica Leigh Ledingham, Jeffrey Daniel Martin, Bashar Oussama Salah
  • Patent number: 10278988
    Abstract: A method of treating a mammal, comprising administering a therapeutically effective amount of a poly-oxygenated metal hydroxide composition to a mammal to reduce a proliferation of hypoxic carcinoma cells, wherein the poly-oxygenated metal hydroxide composition comprises a clathrate containing free oxygen gas (O2) molecules. The carcinoma cells may comprise prostrate carcinoma (22Rv1). The poly-oxygenated metal hydroxide material is configured to provide bioavailable oxygen gas molecules to a mammal when administered to the mammal. The poly-oxygenated metal hydroxide composition can be administered intravenously, directly to carcinoma cells, and orally. The composition may comprise a fluid, where the poly-oxygenated metal hydroxide composition is soluble in the fluid.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: May 7, 2019
    Assignee: BAYLOR UNIVERSITY
    Inventors: Erica D. Bruce, John W. Woodmansee, Jr.
  • Patent number: 10279080
    Abstract: A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles and a suspending agent comprising hyaluronic acid. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: May 7, 2019
    Assignee: SpineOvations, Inc.
    Inventors: Stuart Young, Neville Alleyne, Nicholas John Manesis
  • Patent number: 10272181
    Abstract: The object of the present invention is a method for obtaining an injectable hydrogel based on hyaluronic acid containing lidocaine hydrochloride and an alkaline agent, sterilized with heat, having hyaluronic acid concentration and flow properties, equivalent to those of the corresponding hydrogel based on hyaluronic acid not containing any lidocaine hydrochloride. The present invention also relates to various uses of the aforementioned hydrogel.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: April 30, 2019
    Assignee: ANTEIS S.A.
    Inventor: Samuel Gavard Molliard
  • Patent number: 10272156
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa·s and optionally one or more adjuvants.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: April 30, 2019
    Assignee: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Meinolf Brackhagen, Nicholas S. Grasman, Mark J. Hall, Steven J. Guillaudeu, Robert L. Schmitt, Matthias Knarr
  • Patent number: 10265341
    Abstract: The present invention relates to a hydrogel formulation containing an oxidative reduction potential (ORP) water solution and a gelling agent. The invention further provides a method for treating or preventing a condition in a patient comprising topically administering to a patient a therapeutically effective amount of a hydrogel formulation comprising an oxidative reductive potential solution and a gelling agent. A method for promoting wound healing in a patient is also provided.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 23, 2019
    Assignee: Sonoma Pharmaceuticals, Inc.
    Inventor: Robert Northey
  • Patent number: 10265436
    Abstract: The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component, the first and second high molecular weight components each being selected from the group consisting of polyglycans and polypeptides, wherein at least one of the first and second high molecular weight components is immobilized (e.g., by covalent cross-linking) to the surface of the substrate.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: April 23, 2019
    Assignee: Pioneer Surgical Technology, Inc.
    Inventors: Francis Vincent Lamberti, Richard Chris Klann, Ronald Stewart Hill
  • Patent number: 10265308
    Abstract: The present invention provides a simple and improved dosage form that provides a controlled release of methylphenidate contained in the core thereof. The invention also provides methods of administering the dosage form and of treating conditions that are therapeutically responsive to methylphenidate. The dosage form exhibits improved resistance to alcohol-related dose dumping.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: April 23, 2019
    Assignee: OSMOTICA KERESKEDELMI ES SZOLGALTATO KFT
    Inventors: Hernan D. Benedetti, Cristian R. Franco, Guido S. Bigatti, Joaquina Faour, Ana C. Pastini
  • Patent number: 10264787
    Abstract: Larvicide and pupicide formulation and methods of administration thereof, harmless for humans and other animals, able to kill all the instars larval stages and pupae in about two hours and fifteen minutes, respectively, with no impact on the environment. Larvicide/pupicide formulation and methods of administration thereof for killing larvae and pupae of Anopheles gambiae and An. stephensi, main vectors of malaria, and Aedes aegypti and Ae. albopictus, main vectors of dengue, Zika virus, chikungunya and yellow fever.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: April 23, 2019
    Assignee: BIOVECBLOK s.r.l.
    Inventors: Claudia Damiani, Aurelio Serrao, Matteo Valzano, Vincenzo Cuteri, Riccardo Arigoni
  • Patent number: 10265294
    Abstract: The present invention provides the eutomeric isomer of the compound of formula (I), or a salt or solvate thereof, which can be used to treat epithelial cancer in a subject. In certain embodiments, the compound of formula (I) can be used in combination with AICAR and/or cisplatin.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: April 23, 2019
    Assignee: Yale University
    Inventors: Gil G. Mor, Ayesha Alvero
  • Patent number: 10265253
    Abstract: The invention relates to a clear composition which contains at least one anionic surfactant, a betaine surfactant, an N-methyl-N-acylglucamine, a triglyceride oil, a solvent and optionally an additive. The invention also relates to a method for producing the composition. The invention further relates to the use of the composition for the treatment or care of skin or hair, or for use as a shampoo, face cleaner, liquid cleaner or shower gel.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: April 23, 2019
    Assignee: Clariant International Ltd.
    Inventors: Peter Klug, Carina Mildner
  • Patent number: 10258572
    Abstract: A composition of goserelin sustained release microspheres is provided. The microspheres comprise goserelin, at least one poly (lactide-co-glycolide) and poloxamer or PEG. The sustained release microspheres have comparatively high bioavailability, which promotes the drug taking its full effect and have entrapment efficiency over 90%.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: April 16, 2019
    Assignee: Shandong Luye Pharmaceutical Co., Ltd.
    Inventors: Wei Sun, Xuemei Zhang, Tao Wang, Guangyi Leng, Kaoxiang Sun, Youxin Li, Wanhui Liu
  • Patent number: 10258545
    Abstract: Oily cosmetics which exhibit sufficient filling properties of viscosity and fluidity during the heating and melting steps of manufacture, significantly ameliorate the problems associated with the aggregation of powder, and have excellent usability characteristics, contain coated powder obtained by subjecting base material powder to composite treatment using at least alkylsilane and phospholipid through a wet method. The oily cosmetics contain 5 to 65 mass % of powder component, 0 to 40 mass % of solid oil, and 25 to 95 mass % of liquid oil, in which the content of the coated powder in the powder component is 0.1 to 65 mass % based on the total amount of the oily cosmetics.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: April 16, 2019
    Assignee: TOKIWA CORPORATION
    Inventors: Shunsuke Togashi, Kazunori Ogino
  • Patent number: 10258555
    Abstract: The present invention is directed to a shampoo composition for hair frizz reduction comprising from about 0.1% to about 20% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following: wherein R? is —COOY, sulfonic acid, or C?CH—COOY, Y is hydrogen or a metal ion, R1, R2, R3, R4, R5 is hydrogen, methyl, ethyl, propyl, vinyl, allyl, methoxy, ethoxy, hydroxyl, halogen, sulfate, sulfonate, nitro, or —CH?CH—COOR, and wherein the moisture control material is an acidic material and further wherein the moisture control material has a % Protein binding higher than 20 and Molecular Volume lower than 500 and Partition coefficient octanol to water (log P) lower than 3 and hydrogen binding higher than 10 and pKa lower than 5.0.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: April 16, 2019
    Assignee: The Procter and Gamble Company
    Inventors: Supriya Punyani, Brian Xiaoqing Song, Jennifer Mary Marsh, Tiffany Tien-Yun Yang
  • Patent number: 10258558
    Abstract: Cosmetic products and methods for temporarily shaping keratin-containing fibers using the cosmetic products are provided herein. A cosmetic product for temporarily shaping keratinic fibers includes a cosmetic preparation. The cosmetic preparation contains at least one copolymer a1) that is constructed from at least the following monomer units: (meth)acrylic acid, (meth)acrylic acid alkyl ester, and (meth)acrylic acid hydroxy alkyl ester. The cosmetic preparation further contains at least one copolymer a2) that is constructed from at least the following monomer units: styrene, and at least one of acrylic acid or methacrylic acid. The proportion by weight of copolymers a1) and a2) with respect to the total weight of the cosmetic preparation is about 1.0 to about 10 wt %.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: April 16, 2019
    Assignee: Henkel AG & Co. KGaA
    Inventors: Thorsten Knappe, Pamela Kaftan, Maria Catalina Bermudez Agudelo, Tim Bethge