Patents Examined by Evelyn Y Pyla
  • Patent number: 9909161
    Abstract: A method and system for evaluating the competence for transplantation of a graft sample containing cells capable of multinucleation are provided. In one form, the method includes determining multinucleating ability as an indicator representing the capacity for multinucleation of the cells capable of multinucleation.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: March 6, 2018
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Kenta Sakamoto
  • Patent number: 9901548
    Abstract: This disclosure relates to compositions and methods for encapsulating biomaterials such as cells to prevent immune responses. In certain embodiments, the disclosure relates to capsules comprising a cell or cells gelled in alginate coated with a layer that prevents migration of immune molecules to the cell surface and an outer capsule layer comprising non-immunogenic material optionally containing immunosuppressive agents. In certain embodiments, the cells are capable of generating insulin that emanates from the capsule.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: February 27, 2018
    Assignee: EMORY UNIVERSITY
    Inventors: Collin J. Weber, Susan A. Safley, Kereen S. Gordon, Nicholas E. Simpson
  • Patent number: 9877915
    Abstract: Disclosed herein is a skin external composition containing a red yeast rice extract. More particularly, disclosed is a skin external composition containing a red yeast rice extract which can increase the production of loricrin in keratinocytes and to strengthen the skin barrier function, thereby exhibiting an excellent effect of improving skin moisturization.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: January 30, 2018
    Assignee: Amorepacific Corporation
    Inventors: Dong Won Choi, Hong Guen Park, Han Byul Kim, Jin Sup Shim, In Hye Ha, Youn Joon Kim, Byung Young Kang
  • Patent number: 9845459
    Abstract: The present invention relates to a method of obtaining high purity stem cells from tissue, comprising: providing an impurity-containing cell mass obtained from a tissue; providing a filter device which comprises a cylinder structure, wherein the cylinder structure comprise an inlet and an outlet below and a content configured inside the cylinder structure between the inlet and the outlet; culturing the impurity-free cell mass on a polymeric film, wherein target stem cells of the impurity-free cell mass conjugate into a spheroid cell population; collecting the spheroid cell population from the polymeric film to obtain high purity target stem cells. According to the method of the present invention, stem cells can be rapidly and easily obtained from tissue. Only a small amount of tissue sample is required and the stem cells obtained can be readily used in clinical applications such as autotransplantation without the requirement of in vitro amplification.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: December 19, 2017
    Assignee: National Taiwan University
    Inventors: Shan-Hui Hsu, Guo-Shiang Huang, Niann-Tzyy Dai, Lien-Guo Dai