Abstract: Disclosed are nanoparticles, such as carbon nanotubes or other graphitic sheet materials having extended aromatic surfaces, which are used to deliver active agents such as drugs, labels or dyes (termed for convenience a “drug”) to the interior of cells. The nanoparticles are functionalized by a hydrophilic polymer or adsorption of an amphiphilic molecule to render them stable in suspension. The drug is therefore capable of release in the cell exterior. The drug is more rapidly released at lower pH, as found e.g., in tumor cells. The drug may also be linked to a branched chain hydrophilic polymer, so that each polymer molecule carries more than one drug bound by a cleavable linker.
Type:
Grant
Filed:
July 24, 2008
Date of Patent:
September 17, 2013
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Hongjie Dai, Zhuang Liu, Xiaolin Li, Xiaoming Sun
Abstract: In order to provide a controlled-release insect-controlling resin molded product and a insect-controlling resin composition for making such a controlled-release insect-controlling resin molded product that have immediate effectiveness, residual effectiveness, and preservation stability and that are excellent in merchantability and manufacturing control, the present invention uses an insect-controlling resin composition including a polyvinyl chloride resin containing a non-vaporizable insect-controlling component and erucic acid.
Abstract: The present invention relates to a method for controlling coniferous plants, in particular naturally seeded coniferous plants (wildling conifers), wherein an effective amount of at least one herbicide selected from the group consisting of sulfentrazone, carfentrazone, their agriculturally acceptable salts and their agriculturally acceptable derivatives is applied to the coniferous plants to be controlled or to their parts, such as roots, leaves, seeds or germinants.
Type:
Grant
Filed:
December 17, 2004
Date of Patent:
September 17, 2013
Assignee:
BASF Aktiengesellschaft
Inventors:
Joseph Zawierucha, Glenn W. Oliver, Harold E. Quicke
Abstract: Cosmetic/sunscreen compositions contain a combination of at least one dibenzoylmethane sunscreen compound and a photostabilizing amount of at least one dithiolane compound of formula (I) below:
Abstract: The invention relates to herbicidal compositions comprising an effective amount of an active ingredient combination composed of (a) at least one substituted thien-3-ylsulfonylamino(thio)carbonyltriazolin(thi)one of the formula (I) in which R1, R2 and R3 are as defined in the description, —or salts of the compounds of the formula (I)— and (b) one or more compounds from a second group of herbicides which comprises selected 4-HPPD inhibitors, and, if desired, additionally (c) a crop plant tolerance promoter compound. The invention further relates to the use of the compositions for controlling unwanted plant growth and to a process for producing the compositions.
Type:
Grant
Filed:
February 19, 2005
Date of Patent:
September 10, 2013
Assignee:
Bayer CropScience AG
Inventors:
Markus Dollinger, Hans-Joachim Santel, Ernst Rudolf Gesing, Erwin Hacker
Abstract: A hair cosmetic composition containing a polyether polycarbonate having a structural unit represented by the following formula (1): [wherein A represents a C2 to C6 alkylene group; n represents an average number of 5 to 1,000; p represents an average number of 5 to 100; and (n×p) units of AO may be the same or not].
Abstract: Solid dosage formulations of nitazoxanide or a nitazoxanide analogue are provided that comprise a controlled release portion and an immediate release portion. The pharmaceutical composition is typically in the form of a bilayer solid oral dosage form comprising (a) a first layer comprising a first quantity of nitazoxanide or analogue thereof in a controlled release formulation; and (b) a second layer comprising a second quantity of nitazoxanide or analogue thereof in an immediate release formulation. Method of using the formulations in the treatment of hepatitis C are also provided.
Abstract: Anti-viral tissues are provided with a pH indicator which can communicate to a tissue user by means of visual indicia, via color changes, that the tissue has active ingredients. Furthermore, the pH indicators can be used to illustrate neutralization of the pH of infected nasal discharge, which has a higher pH than healthy nasal discharge, giving the user a reason to believe that the product is working to deactivate virus.
Type:
Grant
Filed:
June 29, 2010
Date of Patent:
August 27, 2013
Assignee:
Kimberly-Clark Worldwide, Inc.
Inventors:
John Gavin MacDonald, Stephanie M. Martin, Ronnie L. Phillips, Xuedong Song
Abstract: Herein described is a novel crystalline form of the hydrochloride of the (4-hydroxycarbamoyl-phenyl)-carbamic acid (6-dimethylamino methyl-2-naphtalenyl) ester. In particular, herein described is a polymorph of the hydrochloride of the (4-hydroxycarbamoyl-phenyl)-carbamic acid (6-dimethylamino methyl-2-naphtalenyl) ester, characterized by a Powder X Ray Diffraction spectrum as indicated in FIG. 1, and/or by a DSC profile as indicated in FIG. 2, and/or by a TGA profile as indicated in FIG. 3 and/or by an IR spectrum as indicated in FIG. 4.
Abstract: The present invention relates to a composition including at least one retinoid and at least one chromenone derivative and the use thereof for the preparation of a cosmetic article to be used for the topical application to skin, hair or nails.
Type:
Grant
Filed:
May 6, 2008
Date of Patent:
August 27, 2013
Assignee:
Johnson & Johnson Consumer France, S.A.S.
Inventors:
Thierry Oddos, Otto Von Stetten, Anne-Sophie Brillouet, Nathalie Issachar
Abstract: The present invention teaches how to change the skin color perception, mainly the facial color from red, blue or yellow to white appearance, using quantum and optical principles. By selecting the right size and material of particles compounded in cosmetic preparations and applying the preparations to the skin, the scattering and/or emission from micro- and nanoparticles can provide a complementary color or in proximity to that complementary color of the skin color. The mixture of the color provided by the particles and the reflected color from the skin will whiten the skin or make inconspicuous of the hyperchromic portion of the skin. The invention can also be used for other applications in which the particles can be applied to a surface or blended into a material, such as, for example, automobile paint, house paint, glass color and nail polish.
Type:
Grant
Filed:
January 22, 2007
Date of Patent:
August 27, 2013
Assignee:
Research Foundation of the City University of New York
Inventors:
Robert R. Alfano, Xiaohui Ni, Manuel Zevallos
Abstract: An object of the present invention is to provide a method for producing bioactive composites having imparted thereto bioactivity, to thereby form and grow in vivo or in vitro a coating layer containing a calcium phosphate compound as the major component with a high adhesion strength on the surface of various types of porous substrates such as a porous shaped body comprising an organic polymer. The means for solving the problem is characterized by comprising at least (1) a step of immersing a porous substrate in a solution containing at least calcium ions and hydrogenphosphate ions, thereby distributing the solution to the inside of at least a part of the pores of the substrate, and (2) a step of depositing fine particles containing a calcium phosphate compound as the major component inside the pores into which the solution is introduced.
Abstract: Aqueous hair care compositions which provide hair styling, hair lightening and hair conditioning benefits are disclosed. The compositions provide hair lightening effects greater than that which would typically be achieved using hydrogen peroxide solutions alone. The compositions comprise a stabilized oxidative compound, a film-forming hair care polymer, a cationic hair care polymer, and water. The method of conditioning, styling and coloring hair utilizing the disclosed compositions is also disclosed.
Abstract: Process for the preparation of a composition including an oil phase, an aqueous phase, at least one emulsifying system of water-in-oil (W/O) type, optionally at least one emulsifying system of oil-in-water (O/W) type, in the form of an inverse latex including from 20% to 70% by weight and preferably from 25% to 50% by weight of a branched or crosslinked polyelectrolyte, characterized in that the polyelectrolyte is a copolymer of 2-acrylamido-2-methylpropanesulfonic acid partially or totally salified with acrylamide and optionally one or more monomers chosen from monomers containing a partially or totally salified weak acid function and/or from neutral monomers other than acrylamide, the production process being characterized in that the preparation of the aqueous phase includes the dissolution in the aqueous medium of solid 2-acrylamido-2-methyl propanesulfonic acid before neutralization. Cosmetic, dermopharmaceutical or pharmaceutical composition including the inverse latex directly obtained by the process.
Type:
Grant
Filed:
October 15, 2008
Date of Patent:
August 20, 2013
Assignees:
Societe d'Exploitation de Produits pour les Industries Chimiques SEPPIC, Scott Bader Company Limited
Inventors:
Paul Mallo, Olivier Braun, Francois Guy, Audrey Bonnardel
Abstract: A tissue product comprising an additive composition onto at least the surface of a fibrous article in order to increase the surface potential of the article, while retaining or improving manufacturing efficiency is disclosed. The additive composition comprises a bacteriostatic component and more preferably a water-soluble adhesive component and a bacteriostatic component. In some aspects, the additive may also contain additional water-soluble modifier components. Tissue products according to the present disclosure can attract and trap negatively charged matter, such as bacteria, into the tissue web. As such, tissue products can pickup bacteria from a surface and substantially hold the bacteria in the sheet to help prevent spreading bacteria to other surfaces.
Type:
Grant
Filed:
December 28, 2010
Date of Patent:
August 13, 2013
Assignee:
Kimberly-Clark Worldwide, Inc.
Inventors:
Dave Allen Soerens, Cathleen Mae Uttecht, Bao Trong Do, SooYeon Oh
Abstract: Agent for treating fibers containing keratin, particularly human hair, comprising, in a cosmetically acceptable carrier: (a) at least one amphiphilic, cationic polymer having at least one structural unit of formulae (I) to (IV), wherein; R1 and R4 are independently hydrogen or a methyl group, X1 and X2 are independently oxygen or an NH group, A1 and A2 are independently an ethane-1,2-diyl, propane-1,3-diyl or butane-1,4-diyl group, R2, R3, R5 and R6 are independently a (C1 to C4)-alkyl group, R7 is a C8 to C30)-alkyl group and; (b) at least one film-forming cationic and/or stabilizing cationic polymer. The invention also relates to use of agents for temporarily styling hair and for haircare, particularly as an aerosol hairspray or mousse.
Abstract: The present invention has an object to provide a gel composition which has an excellent skin whitening effect and shows high storage stability even when ascorbic acid, a salt of ascorbic acid, an ascorbic acid derivative, and a salt of an ascorbic acid derivative is blended, and to provide a pack cosmetic using the gel composition. The gel composition, which comprises the following components (A)-(D): (A) a tamarind seed polysaccharide; (B) a polyhydric alcohol; (C) at least one or more of ascorbic acid, a salt of ascorbic acid, an ascorbic acid derivative, and a salt of an ascorbic acid derivative; and (D) water.
Abstract: The invention provides a gel-type water absorbent with rich flexibility and elasticity, with less variation in strength of gel during preservation, with low viscosity of sol, with easy processability, having a physical property with extremely less water discharge, and having functions of water absorbency and water solubility. The gel-type water absorbent contains a tamarind seed polysaccharide including 90% or more dietary fiber, 1% or less protein and 1% or less ash; and a water-soluble organic substance including at least one or more of a polyhydric alcohol and water-soluble surfactant.
Type:
Grant
Filed:
May 16, 2005
Date of Patent:
August 6, 2013
Assignee:
The Nisshin Oillio Group, Ltd
Inventors:
Yukiko Oi, Keiichi Oyama, Yuji Uzuhashi, Masaaki Kojima
Abstract: A topical composition for the treatment of mammalian skin dermatoses comprising a sulfacetamide or a derivative thereof and at least 1 sunscreen wherein the sunscreen is present in a sufficient amount to produce a sun protection factor of about 1.6 to about 20.6. Also provided is a method of treating mammalian dermatoses by administering a topical composition comprising a sulfacetamide or a derivative thereof and at least 1 sunscreen wherein the sunscreen is present in a sufficient amount to produce a sun protection factor of about 1.6 to about 20.6.
Abstract: The invention relates to a composition comprising a) silver and/or one or more silver compound and b) one or more biocidal active ingredients of the isothiazoline.
Type:
Grant
Filed:
February 20, 2008
Date of Patent:
July 30, 2013
Assignee:
Clariant Finance (BVI) Limited
Inventors:
Uwe Falk, Michael Marcus Walter, Joerg Grohmann