Patents Examined by Gina C Justice
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Patent number: 12370131Abstract: The invention relates to a compound (1) comprising at least 50% by weight of a functional agent, characterized in that it also comprises a waxy matrix (3), within which said functional agent is dispersed, wherein said compound (1) is solid at room temperature and intended to be dispersed by fluidization and/or solubilization within a cosmetic and/or dermatological composition to incorporate therein said functional agent, said functional agent being formed from solid particles (2) having undergone a surface treatment resulting in a reductions in the absorption capacity of the waxy matrix (3) by said treated solid particles (2), as compared to untreated solid particles of the same nature. The invention also relates to a formulation of cosmetic and/or dermatological compositions.Type: GrantFiled: April 23, 2020Date of Patent: July 29, 2025Assignee: MIYOSHI EUROPEInventors: Sébastien Gougeon, Quentin Dauphin, Laetitia Sellal, Stephane Nicolas, Pauline Bosmet
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Patent number: 12324793Abstract: The present invention relates to a pharmaceutical composition for renal protection in chronic kidney disease, which contains a citric acid, a pharmaceutically acceptable salt of a citric acid, or a hydrate thereof; and a mixture of the citric acid, the pharmaceutically acceptable salt of the citric acid, and the hydrate thereof, and is a tablet.Type: GrantFiled: October 17, 2019Date of Patent: June 10, 2025Assignees: TOHOKU UNIVERSITY, NIPPON CHEMIPHAR CO., LTD.Inventors: Michiaki Abe, Seizo Koshiba, Koichiro Nishioka, Kazuhiko Kawaguchi, Satomi Yamasaki, Yasuyuki Teranaka
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Patent number: 12310976Abstract: The present invention is directed to orally administered compositions of topically acting corticosteroids for the treatment of inflammation of the gastrointestinal tracts such as eosinophilic esophagitis. The present invention also provides a method for treating conditions associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention as orally disintegrating tablets comprising a topically active corticosteroid adsorbed onto a pharmaceutically acceptable carrier such as silicified microcrystalline cellulose.Type: GrantFiled: December 22, 2021Date of Patent: May 27, 2025Assignee: Ellodi Pharmaceuticals, L.P.Inventors: Michael A. Gosselin, Jin-Wang Lai, Gopi M. Venkatesh
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Patent number: 12295980Abstract: The field of the invention relates to processes for preparing Asparagopsis oil compositions, comprising extracting at least one bioactive from a biomass of Asparagopsis into an oil to form the compositions. These compositions are suitable for reducing total gas production and/or methane production in a ruminant or pseudo-ruminant animal.Type: GrantFiled: December 6, 2019Date of Patent: May 13, 2025Assignee: FutureFeed Pty LimitedInventors: Rocky De Nys, Marie Elisabeth Magnusson
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Patent number: 12296038Abstract: Provided is a very stable topical composition. A topical composition is prepared that contains (A) from 1 to 40% by mass of at least one type selected from the group consisting of ascorbic acid and salts of ascorbic acid; (B) at least 20% by mass of a diol having three carbon atoms; (C) at least one type selected from the group consisting of tocopherol, salts of tocopherol, and derivatives of tocopherol; and (D) water, wherein the mass ratio of component (D) to component (A) is from 0.5 to 5.0 and the topical composition includes less than 20% by mass of glycol ether.Type: GrantFiled: September 25, 2019Date of Patent: May 13, 2025Assignee: ROHTO PHARMACEUTICAL CO., LTD.Inventors: Yu Kitaoka, Mariko Iwai, Sho Yamashina
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Patent number: 12290579Abstract: Disclosed herein is an effect pigment having a layer stack which comprises a highly reflective metallic flake having a first major interface and opposed to this first interface a second major interface, and at least one side surface and directly adjacent on one or of both of these major interfaces a layer of a semiconducting material having an average atomic composition of: a) Si(1-x)Snx, wherein 0<x<0.90 or b) Ge(1-y)Sny, wherein 0<y?0.80 or c) Si(1-m-n)GemSnn, wherein 0<m<1.00, 0<n<1.00 and with the proviso that m+n<1.00.Type: GrantFiled: December 6, 2022Date of Patent: May 6, 2025Assignee: ECKART AMERICA CORPORATIONInventors: Devin Schmitt, Jonglak Choi
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Patent number: 12290509Abstract: Methods of reducing hepatitis delta virus (HDV) viral loads in a patient are provided. In some embodiments, the method comprises treating the patient with lonafarnib-ritonavir co-therapy. In some embodiments, the method further comprises treating the patient with an interferon.Type: GrantFiled: September 15, 2023Date of Patent: May 6, 2025Assignee: EIT Pharma, Inc.Inventors: David A. Cory, Ingrid Choong, Jeffrey S. Glenn
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Patent number: 12285454Abstract: The present invention discloses an anti-aging Chinese herb extract, an extraction method and a use thereof. The ginseng-Astragalus membranaceus extract of the present invention comprises 20 to 30% of astragaloside, 1 to 5% of ginsenoside Rg1, 2 to 6% of ginsenoside Re, 0.2 to 0.5% of ginsenoside Rb1. There are 17 characteristic peaks in high-performance liquid chromatography fingerprints of the extract. The extract can effectively improve activity of telomerase, delay cell aging, and can be applied to preparation of an anti-aging product.Type: GrantFiled: August 10, 2020Date of Patent: April 29, 2025Assignee: HEALTH LIFE BIOSCIENCES INCInventors: Jin Chen, Yunyan He, Jun Su, Ai Li
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Patent number: 12275677Abstract: The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5372, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.Type: GrantFiled: December 19, 2019Date of Patent: April 15, 2025Assignees: Universite de Lorraine, Institut National de la Recherche AgronomiqueInventors: Sophie Slezack-Deschaumes, Séverine Piutti, Pierre L'Yvonnet, Sandro Roselli
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Patent number: 12268773Abstract: A shear-thinning therapeutic composition is provided along with methods of making and using the therapeutic composition.Type: GrantFiled: July 19, 2021Date of Patent: April 8, 2025Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Xiaochu Ding, Jin Gao, Yadong Wang
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Patent number: 12263191Abstract: A sterile micronized composition prepared from intact human placental tissue for wound healing. The sterile micronized composition includes micronized human amnion; micronized human chorion; and micronized human intermediate spongy layer. In certain aspects, the composition is prepared from intact placental tissue comprising a human amnion layer, human chorion layer, and an intact human intermediate spongy layer positioned between the human amnion layer and human chorion layer such that immediately before micronization the human amnion layer and the human chorion layer are not separated from one another.Type: GrantFiled: March 1, 2024Date of Patent: April 1, 2025Assignee: BioStem Technologies, Inc.Inventors: Jason V. Matuszewski, Wendy W. Weston
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Patent number: 12239760Abstract: A hydrogel includes a polysaccharide including aldehyde groups and carboxy groups, a functionalized chitosan, and iron (III) ions. The hydrogel further includes particles including a core including a carboxy-functionalized polythiophene and a shell including polydopamine. A wound dressing includes the hydrogel and a base layer selected from the group consisting of a gauze, lint, plaster, bandage and cotton wool. The hydrogel is attached or adhered to the base layer.Type: GrantFiled: September 26, 2024Date of Patent: March 4, 2025Assignees: NAJRAN UNIVERSITY, XI'AN JIAOTONG UNIVERSITYInventors: Saeed A. Alsareii, Baolin Guo, Lipeng Qiao, Abdulrahman Manaa Alamri, Farid A. Harraz
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Patent number: 12232497Abstract: A mixed bacteria for promoting nodulation and nitrogen fixation of Robinia pseudoacacia and their application are provided. The mixed bacteria includes Kocuria sp. X-22, Microbacterium sp. X-26, and Bacillus sp. X-28, all of which have been preserved in China Center for Type Culture Collection, and the preservation numbers respectively are: CCTCC No: M 2019237; CCTCC No: M 2019238; CCTCC No: M 2019239. The mixed bacteria are watered directly around the seedlings of Robinia pseudoacacia. Compared with the single bacteria control group and the sterile control group, the disclosure can produce synergistic superimposing effects, significantly improve the nodulation rate and symbiotic nitrogen fixation of the Robinia pseudoacacia, and promote the photosynthesis of the Robinia pseudoacacia.Type: GrantFiled: January 12, 2021Date of Patent: February 25, 2025Assignee: NANJING FORESTRY UNIVERSITYInventors: Jiayao Zhuang, Chao Liu, Xiaoxue Wang, Jiaxin Zheng, Kun Tian
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Patent number: 12193438Abstract: Provided herein are methods for providing improved vigor, and especially priming or improving root formation, of plant cuttings and to plant cuttings obtained thereby. Specifically, the methods include the steps of a) contacting a plant cutting with a polymeric solution, or suspension, optionally including one or more plant growth promoting and/or plant protecting compounds, thereby providing a coated plant cutting; b) allowing the polymeric solution, or suspension, of the coated plant cutting to solidify into a complexed coating, thereby providing an encapsulated plant cutting. The encapsulated plant cutting is coated with the complexed coating from the basal cut surface or tip of the plant cutting to less than 60% of the total length of said plant cutting to partially encapsulate the plant cutting with the complexed coating.Type: GrantFiled: May 25, 2016Date of Patent: January 14, 2025Assignee: Dümmen Group B.V.Inventors: Pankaj Bacharam Dhonukshe, Tobias Günter Dummen, Johannes Franciscus Johanna Maria van den Heuvel
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Patent number: 12194122Abstract: The present invention relates to a composition, comprising (a) at least one modified starch, (b) at least one C13-C15 fatty acid, and (c) at least one clay. The amount of each of the ingredients (a) to (c) may be within a specific weight range. The composition according to the present invention is stable, and can be rinsed off from the skin and can leave an enhanced deposition of clay on the skin after rinsing off the composition from the skin.Type: GrantFiled: April 7, 2020Date of Patent: January 14, 2025Assignee: L'OREALInventors: Fan Hu, Masanori Orita
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Patent number: 12150450Abstract: Compositions and methods for insect control are provided. In one example, a method of producing a mycoinsecticide composition comprises: preparing a starter culture to grow a strain of B. bassiana fungus; freezing and storing the prepared starter culture to obtain a fungus mixture; treating the stored fungus mixture to obtain a fungus liquid containing the grown B. bassiana fungus; treating and/or formulating the fungus liquid to obtain the mycoinsecticide composition; and packaging the mycoinsecticide composition. The B. bassiana fungus is preferably of the strain JTDRL-RC5A-HSSE deposited under NRRL Number 67768.Type: GrantFiled: July 11, 2022Date of Patent: November 26, 2024Inventor: John Thomas Sigurdson
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Patent number: 12151013Abstract: The present invention relates to a composition for dyeing keratin fibres comprising at least one aqueous dispersion of particles of hybrid film-forming hydrophobic acrylic polymer, at least one linear block silicone copolymer and at least one pigment. It also relates to a dyeing method in which said composition is applied to the keratin fibres, the operation optionally being followed by a drying operation. The composition makes it possible to obtain a coloured, shampoo-resistant coating that leaves the treated fibres individualized, with an improved cosmetic feel.Type: GrantFiled: July 30, 2021Date of Patent: November 26, 2024Assignee: L'OREALInventor: Karen Teboul
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Patent number: 12144896Abstract: The treatment of cancer using platinum-based compounds includes certain drawbacks such as biocompatibility, loading efficacy, leakage of drugs during storage and in the bloodstream, more particularly due to the nature of the nanocarriers for platinum delivery. A nanosystem that allows improving platinum-based drug in vivo performance, kinetics and efficacy. In particular, nanoparticles useful as drug delivery system, these nanoparticles being formed from at least: (a) platinum-based drug, (b) poly-L-arginine, and (c) hyaluronic acid. Particularly, these nanoparticles have been tested in terms of entrapment efficiency and also carried out in vitro experiments in 2D cell culture (viability studies on B6KPC3, A549 and HT-29 cells) and 3D cell model (spheroids made of HTC-116) and in vivo experiments (by injecting intravenously to mice the nanoparticles or comparative oxaliplatin solution) to prove their efficiency.Type: GrantFiled: September 16, 2019Date of Patent: November 19, 2024Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS—, UNIVERSITE D'ANGERS, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERSInventors: Giovanna Lollo, Jean-Pierre Benoit, Marie Brachet-Botineau
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Patent number: 12138331Abstract: A foaming skin cleanser formulation comprising silver, stearic acid, myristic acid, linoleic acid, propanediol, carbomer, polyquarternium-39, cocamidopropyl hydroxysultaine, pomegranate sterols (cholesterol), Coco-caprylate/caprate, Cocos nucifera, Sodium Cocoyl Isethionate, and mixtures and combinations thereof.Type: GrantFiled: July 27, 2022Date of Patent: November 12, 2024Inventors: Julius Zecchino, Marina Turso
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Patent number: 12115234Abstract: A method for preparing a cosmetic component is provided which includes applying a layer of a dry cosmetic ingredient between a pair of fibrous sheets obtained by electrospinning one or more polymeric materials at least one of which is capable of cold flow under pressure. Sufficient pressure is then applied to the layers of fibrous sheets to cause cold flow of at least some of the polymeric material such that at least parts of the fibrous sheets bond with each other and entrap the cosmetic ingredient in position between them and prevent it from migrating between the sheets during further processing or handling.Type: GrantFiled: October 7, 2019Date of Patent: October 15, 2024Assignee: THE STELLENBOSCH NANOFIBER COMPANY (PTY) LTDInventors: Anton Eugene Smit, Haydn Kriel, Megan Patricia Coates, Justin Stone