Abstract: Systems and methods for analyzing a gas are provided. In some embodiments, the system includes: at least one scrubber including a scrubber material that removes at least one sulfur compound from the gas to produce a scrubbed gas; at least one gas sensor in fluid communication with the at least one scrubber, the at least one gas sensor sensing at least one remaining sulfur compound in the scrubbed gas. In some embodiments, the systems and methods disclosed herein may be used to analyze individual odorants in a hydrocarbon gas such as natural gas.

Abstract: The present disclosure relates, in some embodiments, to a system for measuring capillary electrophoresis current. The system includes a plurality of capillaries, where each capillary has a cathode end and an anode end. The system further includes a plurality of cathode buffers. Each of the cathode buffers is configured to be electrically isolated from the other cathode buffers. Further, each cathode buffer is associated with one capillary of the plurality of capillaries. The cathode end of each capillary is immersed in its associated cathode buffer. The system includes a plurality of current sensors, each current sensor associated with one capillary of the plurality of capillaries for measuring current. In some embodiments, the plurality of capillaries is four capillaries.

Abstract: Provided is a glycated protein sensor provided with: immobilized protease; immobilized ketoamine oxidase; and a hydrogen peroxide detection section.

Abstract: Biosensors capable of detecting certain biomarkers (e.g., platelet-derived growth factor-BB (PDGF-BB)), as well as methods of fabricating the same and methods of using the same, are provided. The biosensors can be disposable and/or label-free. Electrochemical bipolar exfoliation can be used to exfoliate, reduce, and deposit (in a single step) graphene nanosheets on a desired substrate (e.g., an electrode). Affinity aptamers can be immobilized on the graphene nanosheets disposed on the substrate.

Abstract: There is provided a chloride selective membrane including an epoxide-based matrix reacted with a stoichiometric amount of an amino compound and an activator such that the epoxide-based matrix comprises a number of quaternary ammonium groups.

Abstract: The present disclosure generally relates to a system for monitoring and/or controlling one or more agents, such as cleaning agents, in a wastewater treatment system. The system comprises a bio-electrochemical sensor for monitoring metabolic activity of a population of exo-electrogenic bacteria and providing an electrical output corresponding with the metabolic activity, where the bio-electrochemical sensor comprises an electrode pair and a power source for delivering a voltage across the electrode pair, and an electrical output analyzer for analyzing the electrical output and correlating the electrical output with the one or more agents in the wastewater treatment system. a change in electrical output beyond a threshold indicates that an adjustment in the delivery of the one or more agents is needed. a method and sensor for monitoring and/or controlling a cleaning process in a wastewater treatment system are also provided.

Abstract: A non-enzymatic sensor includes a substrate; a sensor contact disposed on the substrate; and a pH modifying contact disposed on the substrate proximate the sensor contact. The pH modifying contact includes a material that absorbs hydrogen from and expels hydrogen to a fluid when in use in response to applied voltages resulting in an electrically controllable change of pH of the fluid. The pH modifying contact is positioned relative to the sensor contact such that the electrically controllable change of pH of the fluid results in a change in pH of the fluid proximal to the sensor contact to thereby enhanced detection of a substance of interest at the sensor contact without the use of enzymes.

Abstract: A lead-free galvanic oxygen sensor having an aqueous electrolyte and a bismuth anode is disclosed. The electrolyte contains a polyol in addition to water and a salt. Surprisingly, a sensor with such an electrolyte has an increased resistance to passivation. The suppressed passivation of the bismuth anode leads to a sensor lifespan, in some instances, of greater than 100 days. The polyol can be added in the amount of between 20% and 30%. The polyol can comprise D-sorbitol, meso-erythritol, or glycerol. In some instances, the polyol in the electrolyte can increase the time until a sudden rise in potential for the sensor, while maintaining a constant current on the bismuth anode, of greater than 14 minutes.

Abstract: A test sensor heating system is disclosed that provides the desired and different temperatures to at least two different reaction zones based on a fixed potential. The measurement device does not alter the potential applied to the heating system in response to temperature feedback information. The heating system provides the desired and different temperatures to the different reaction zones of the test sensor by varying heating element spacing and/or the resistivity of an associated resistive layer of the test sensor to provide the desired temperature in response to the fixed potential. The system also may provide two or more different temperature zones to the test sensor by using different heating element spacing and/or resistive layer resistivity at different locations of the test sensor.

Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

Abstract: Provided is a device for measuring a microfluid flow velocity, having a structure separable by an ultra-thin film, the device including a first panel including a flow velocity measurement structure configured to measure a flow velocity of a fluid, a second panel configured to be separated from the first panel and including a microfluid channel through which a sample passes, and the ultra-thin film formed in a portion where the first panel and the second panel adjoin each other, the ultra-thin film being configured to separate the first panel and the second panel so that the sample passing through the microfluid channel does not come into direct contact with the flow velocity measurement structure, in which the first panel including the flow velocity measurement structure is usable multiple times repeatedly.

Abstract: A disposable self-sensing signal test strip includes a test strip body. The test strip body has a detection area and a circuit area. The detection area has a detection circuit. An electrochemical processing unit, a wireless transmission unit, and a power source unit are provided in the circuit area. The detection circuit is electrically connected to the electrochemical processing unit. The electrochemical processing unit sends to the detection circuit a control signal for performing detection. After receiving the control signal, the detection circuit reacts electrochemically with the test sample and sends a feedback signal to the electrochemical processing unit. The electrochemical processing unit converts the feedback signal into a detection parameter signal and sends the detection parameter signal through the wireless transmission unit to a receiving unit. The power source unit supplies electricity to the electrochemical processing unit and the wireless transmission unit.

Abstract: A nanopore-based sequencing system includes a plurality of nanopore-based sequencing chips. Each of the nanopore-based sequencing chips comprises a plurality of nanopore sensors. The system comprises at least one flow cell coupled to at least one of the plurality of nanopore-based sequencing chips, wherein the flow cell coupled to the at least one of the plurality of nanopore-based sequencing chips comprises one or more fluidic flow channels that allow a fluid external to the system to flow on top of the nanopore-based sequencing chip and out of the system. The system further comprises a printed circuit board electrically connected to the plurality of nanopore-based sequencing chips.

Abstract: A method for degassing a microfluidic droplet by combining electrowetting and heating to induce formation of gaseous bubbles in the droplet. In an embodiment the methods are carried out on an active matrix of electrowetting electrodes including a hydrophobic coating. A carrier fluid is flowed against the droplet motion propelled by electrowetting to facilitate rapid removal of the gasses departing the droplet.

Abstract: Electrochemical sensors have great promise for point-of-care and in vivo measurement of medically relevant molecules. However, the need for calibrating individual sensors limits the practical applicability of these sensing platforms. The invention provides a novel method of operating electrochemical sensors which obviates the need to calibrate individual sensors against a sample of known concentration. The invention exploits the frequency dependence of electrochemical output signals and the dependence of output signals on the inherent electron transfer kinetics of a selected sensor design. By use of signals generated at a nonresponsive frequency, a normalizing output value is generated that accounts for sensor-to-sensor variation and which enables an accurate calculation of target concentration. The scope of the invention also includes pre-calibrated sensors that may be utilized without calibration steps.

Abstract: A GABA detecting probe having a probe body with both a glutamate (Glu) micro-sensor and a GABA micro-sensor positioned on the probe body. The Glu micro-sensor and the GABA micro-sensor include electrodes having a surface modification with (i) GOx and a binding matrix, and (ii) GABASE, GOx, and the binding matrix, respectively. The sensors are positioned no further apart than 250 um and includes a sentinel site located on the probe body.

Abstract: The invention provides a dry electroblotting system for dry blotting gels, in which the system includes an electroblotting transfer stack that comprises an analysis gel and a blotting membrane, an anode, a body of anodic gel matrix juxtaposed with the anode between the anode and the transfer stack, a cathode, and a body of cathodic gel matrix juxtaposed with the cathode between the cathode and the transfer stack, in which the anodic gel matrix and the cathodic gel matrix each comprise an ion source for electrophoretic transfer. The dry electroblotting system does not use any liquid buffers that are added to the system just before electroblotting (such as when the transfer stack is being assembled). The anode, the cathode, or both can be separate from a power supply and provided as part of a disposable electrode assembly that also includes a body of gel matrix that includes ions for electrophoretic transfer.

Abstract: A gas sampling bag for gas pH measurement includes a main sampling chamber and an electrochemical test strip accommodating chamber for accommodating an electrochemical test strip. The electrochemical test strip includes a strip body, a working electrode, a pH sensing layer, a reference electrode and a solid water absorption layer. The working electrode has a first part located in a detection area of the strip body. The pH sensing layer is formed on the first part. The reference electrode has a second part located in the detection area. The solid water absorbing layer is formed on the detection area and covers the pH sensing layer and the second part. The solid water absorbing layer is used for absorbing or adsorbing water in the gas sample to form an electrical connection between the first and second parts.

Abstract: A dry reagent composition that includes an active redox enzyme that oxidizes an analyte as a specific substrate to produce an inactive reduced form of the enzyme; and a salt of ferricyanide provides improved performance in electrochemical test strips such as those used for detection of glucose. The salt of ferricyanide consists of ferricyanide and positively-charged counter ions, and the positively charged counter ions are selected such that the salt of ferricyanide is soluble in water, and such that the salt of ferricyanide or the crystalline phase of the salt of ferricyanide has a solubility in water and/or a lower E0eff at a concentration of 100 mM than potassium ferricyanide. For example, the salt of ferricyanide may be tetramethylammonium ferricyanide.

Abstract: The disclosure relates to textile biosensors and related systems that can be used for in situ health monitoring and disease detection. The biosensors include a flexible or textile substrate, a working electrode embroidered thereon, a reference electrode embroidered thereon, optionally a counter electrode embroidered thereon, and an enzyme probe bound to the working electrode. The biosensors can be integrated directly onto fabrics and garments to provide lightweight, unobtrusive wearable sensing systems that do not compromise wearer mobility, comfort or attention.