Patents Examined by Gurpreet Kaur
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Patent number: 11467119Abstract: The present disclosure relates to an ion-selective electrode for an electrochemical sensor for determining a measurand representing a concentration of an analyte in a measuring medium, including a probe body made of a first material and a sensor element including a base body made of a second material different from the first material and an ion-selective layer arranged on the base body. The probe body is connected to the base body by way of a liquid-tight joint, where the joint is formed by a receptacle, serving as a first joining partner, and a joining section protruding into the receptacle, serving as a second joining partner.Type: GrantFiled: June 15, 2020Date of Patent: October 11, 2022Assignee: ENDRESS+HAUSER CONDUCTA GMBH+CO. KGInventors: Michael Hanko, Thomas Wilhelm, Matthäus Speck, Lothar Auerswald
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Patent number: 11435338Abstract: Disclosed herein are methods and compositions for determining an improved estimate of the true fractional abundance of target analytes (e.g., specific polynucleotide sequences) in a sample using a nanopore sensor, e.g., by correcting errors inherent to identifying and correlating electrical signals to amounts of a target analyte or reference analyte in a sample.Type: GrantFiled: October 24, 2017Date of Patent: September 6, 2022Assignee: Ontera Inc.Inventors: Yanan Zhao, William McKenna, William B. Dunbar
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Patent number: 11415539Abstract: Methods, electrodes, and sensors for pH sensing using pseudo-graphite are disclosed. In one illustrative embodiment, a method may include coating a pseudo-graphite material onto a surface of an electrode substrate to produce a pseudo-graphite surface. The method may also include exposing the pseudo-graphite surface to a sample to detect organic content in the sample.Type: GrantFiled: March 5, 2019Date of Patent: August 16, 2022Assignees: ABB Schweiz AG, University of IdahoInventors: Nolan Nicholas, Ignatius Cheng, Haoyu Zhu, Humayun Kabir
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Patent number: 11415540Abstract: Methods, electrodes, and electrochemical devices using nitrogen-doped pseudo-graphite are disclosed. In one illustrative embodiment, a method may include doping a pseudo-graphite material with nitrogen to form a doped pseudo-graphite material. The method may also include applying the doped pseudo-graphite material to a surface of a substrate of an electrode.Type: GrantFiled: March 5, 2019Date of Patent: August 16, 2022Assignees: ABB Schweiz AG, University of IdahoInventors: Nolan Nicholas, Ignatius Cheng, Haoyu Zhu, Humayun Kabir, Kailash Hamal, Jeremy May
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Patent number: 11415545Abstract: A gas sensor system (100) comprising at least one first field effect transistor (200) comprising first source and drain electrodes and at least one second field effect transistor (300) comprising second source and drain electrodes different from the first source and drain electrodes. Different responses of the first and second FETs to gases in an environment may be used to differentiate between the gases, for example to differentiate between 1-methylcyclopropene and ethylene in locations where fruit is stored.Type: GrantFiled: March 15, 2018Date of Patent: August 16, 2022Assignee: Sumitomo Chemical Company LimitedInventors: Christopher Newsome, Nicholas Dartnell, Simon Goddard
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Patent number: 11384330Abstract: A device for monitoring a cell culture includes one or more electrochemical sensors configured to be positioned adjacent to or embedded within a medium of a cell culture. The one or more electrochemical sensors are configured to generate signals in accordance with the cell culture. A data storage device is configured to receive and store the signals from the one or more electrochemical sensors. A computation device is configured to analyze the signals from the one or more electrochemical sensors to determine cell activity over time using sensitivity information.Type: GrantFiled: February 3, 2020Date of Patent: July 12, 2022Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Amos Cahan, Guy M. Cohen, Theodore G. van Kessel, Sufi Zafar
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Patent number: 11371958Abstract: An electrochemical device for identifying electroactive analytes. The device includes a substrate; a sample region; a counter electrode; a reference electrode; a working electrode disposed in communication with the substrate, and the working electrode may be an electron conducting fiber. Further, the counter electrode, reference electrode, and working electrode are partially disposed in the sample region configured to be exposed to the electroactive analyte. Further yet, a counter electrode channel, reference electrode channel, and working electrode channel are disposed in the substrate configured to: accommodate each of the counter electrode, reference electrode, and working electrode, respectively, for placement in the respective channels.Type: GrantFiled: November 10, 2017Date of Patent: June 28, 2022Assignee: University of Virginia Patent FoundationInventors: Cheng Yang, B. Jill Venton
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Patent number: 11352272Abstract: The present disclosure generally relates to a system for monitoring and/or controlling one or more agents, such as cleaning agents, in a wastewater treatment system. The system comprises a bio-electrochemical sensor for monitoring metabolic activity of a population of exo-electrogenic bacteria and providing an electrical output corresponding with the metabolic activity, where the bio-electrochemical sensor comprises an electrode pair and a power source for delivering a voltage across the electrode pair, and an electrical output analyzer for analyzing the electrical output and correlating the electrical output with the one or more agents in the wastewater treatment system. a change in electrical output beyond a threshold indicates that an adjustment in the delivery of the one or more agents is needed. a method and sensor for monitoring and/or controlling a cleaning process in a wastewater treatment system are also provided.Type: GrantFiled: November 27, 2017Date of Patent: June 7, 2022Assignee: SENTRY:WATER MONITORING AND CONTROL INC.Inventors: Patrick Desmond Kiely, Monica Cella, Jack Ambler, Rebecca Connolly
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Patent number: 11353419Abstract: A method of detecting acetone in a gas sample, comprising, at an operation temperature of 50° C. or less, exposing the gas sample to a gas sensor comprising an electrode and a sensing material deposited on the electrode, wherein the sensing material comprises tungsten bronze, and a level of the acetone in the gas sample is detected by a change in resistivity of the sensing material.Type: GrantFiled: May 24, 2019Date of Patent: June 7, 2022Assignee: TAO TREASURES, LLCInventors: Xiaonao Liu, Yifeng Shi
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Patent number: 11346805Abstract: Aspects of the present disclosure involve systems, methods, and the like, for an electrochemical sensing platform for point-of-care diagnostic applications. The ES platform may include functionality for many types of ES applications, including but not limited to, voltammetry, galvanometry, amperometry, and electrochemical impedance spectroscopy (EIS). In some embodiments, the platform includes sensor analog front end, stimulus generation, analog sensor data acquisition and conditioning, digital-to-analog conversion, back-end digital signal processing, wired or wireless interface, and a user application for interacting with the platform. In some embodiments, the platform includes a number of functional modules to provide a low cost and high mobility to the device, while maintaining the performance specifications. Signal generation, digital data acquisition/processing may be managed by an on-board microcontroller or off-board computing device.Type: GrantFiled: February 7, 2018Date of Patent: May 31, 2022Assignee: Colorado State University Research FoundationInventors: Thomas W. Chen, Lang Yang
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Patent number: 11327046Abstract: Methods, electrodes, and sensors for pH sensing using pseudo-graphite are disclosed. In one illustrative embodiment, a method may include coating a pseudo-graphite material onto a surface of an electrode substrate to produce a pseudo-graphite surface. The method may also include exposing the pseudo-graphite surface to a sample to measure a pH of the sample.Type: GrantFiled: March 5, 2019Date of Patent: May 10, 2022Assignees: ABB SCHWEIZ AG, UNIVERSITY OF IDAHOInventors: Nolan Nicholas, Ignatius Cheng, Haoyu Zhu
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Patent number: 11327041Abstract: Provided are devices and methods for a rapid, non-perturbative and energy-efficient technique for pH sensing based on a flexible graphene electrode. This technique does not require the application of gate voltage or source-drain bias, and demonstrates fast pH-characterization with precision. The disclosed technology is suitable for in vivo monitoring of tumor-induced pH variation in tissues and detection of pH changes as required in a DNA sequencing system.Type: GrantFiled: March 13, 2017Date of Patent: May 10, 2022Assignee: The Trustees of the University of PennsylvaniaInventors: Alan T. Johnson, Jr., Jinglei Ping
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Patent number: 11320390Abstract: A nanopore measurement circuit includes a first analog memory configured to store a first electrical value corresponding to a first measurement sample of a nanopore and a second analog memory configured to store a second electrical value corresponding to a second measurement sample of the nanopore. The nanopore measurement circuit also includes a measurement circuitry configured to provide an output indicating a difference between the first electrical value of the first analog memory and the second electrical value of the second analog memory.Type: GrantFiled: April 28, 2020Date of Patent: May 3, 2022Inventors: Santiago Fernandez-Gomez, Bill Maney, Hui Tian
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Patent number: 11313826Abstract: An integrated chemical sensor device includes a chemical sensor comprising at least one transistor and having an external sensing surface electrically coupled to a node of the at least one transistor. There is an initialization circuit connected to the base of the at least one transistor configured to set an operating point for the at least one transistor. There is a temperature sensor control circuit coupled to the chemical sensor circuit. The temperature sensor includes a temperature sensor, an analog-to-digital (A/D) converter coupled to the temperature sensor, and a proportional-to-absolute-temperature (PTAT) circuit configured to generate a PTAT reference voltage for temperature compensation. The temperature sensor control circuit is configured to compensate for a change in temperature of the at least one transistor.Type: GrantFiled: April 24, 2019Date of Patent: April 26, 2022Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Chitra Subramanian, Sufi Zafar
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Patent number: 11313825Abstract: A gas sensor (1) including a sensor element (10) and a separator (90) having an element hole (90 h), as viewed from one of a forward-end or a rear-end side in the axial direction. The separator has end surfaces (90 e) located axially farthest toward the one of the forward-end or the rear-end side, recess regions (90 h), (90 r 1) and (90 r 2) recessed from the end surfaces, and regions R1 and R2. First regions R1 are determined by eliminating a region SB occupied by the sensor element from a region SA defined by imaginary short-side lines and the outer edge of the separator. Second regions R2 are determined by eliminating the region SB from a region SC defined by imaginary long-side lines and the outer edge of the separator. S2/S1?0.5 is satisfied, where S1 is the total area of R1 and R2, and S2 is the total area of the recess regions.Type: GrantFiled: June 25, 2020Date of Patent: April 26, 2022Assignee: NGK SPARK PLUG CO., LTD.Inventors: Sunchao Liu, Takehiro Oba
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Patent number: 11307163Abstract: A carbon nanotube-based reference electrode and an all-carbon nanotube microelectrode assembly for electrochemical sensing and specialized analytics are disclosed, along with methods of manufacture, and applications including detection of ionic species including heavy metals in municipal and environmental water, monitoring of steel corrosion in steel-reinforced concrete, and analysis of biological fluids.Type: GrantFiled: June 16, 2017Date of Patent: April 19, 2022Assignee: University of CincinnatiInventors: Noe Alvarez, Daoli Zhao, I, William Heineman, Vesselin Shanov, David Siebold
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Patent number: 11293892Abstract: There is provided a chloride selective membrane including an epoxide-based matrix reacted with a stoichiometric amount of an amino compound and an activator such that the epoxide-based matrix comprising a number of quaternary ammonium groups.Type: GrantFiled: May 17, 2016Date of Patent: April 5, 2022Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Bo Peng, David Thompson
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Patent number: 11262333Abstract: A method for concentrating electrically charged objects in a non-Newtonian liquid medium comprises: feeding a sample containing electrically charged objects into a channel having a flow axis, a first transverse cross-section orthogonal to the flow axis, and at least one second transverse cross-section orthogonal to the flow axis, one dimension of the second cross-section being less than the corresponding dimension of the first cross-section; and applying a hydrodynamic flow in a direction of the channel together with the application, in the opposite direction, of an electric field in the channel, thus making it possible to move the electrically charged objects in the channel along the flow axis from the first cross-section to the second cross-section, stop the objects, and concentrate the objects in at least one area upstream from the second transverse cross-section.Type: GrantFiled: August 3, 2015Date of Patent: March 1, 2022Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Aurélien Bancaud, Hubert Ranchon, Thierry Leichle, Pattamon Teerapanich
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Patent number: 11262345Abstract: A method for measuring a glycated protein in a sample, the method comprising (1) a step of allowing a sample in which a degradation product has been generated from a glycated protein by a protease to react with an oxidoreductase in the presence of an electron mediator to generate a reduced electron mediator; and (2) a step of detecting the reaction state in the step (1) by an electrochemical technique using an interdigitated electrode.Type: GrantFiled: September 1, 2016Date of Patent: March 1, 2022Assignee: Ultizyme International Ltd.Inventors: Yuki Ueda, Koji Sode, Wakako Tsugawa, Masaaki Kurita, Takashi Nishimori
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Patent number: 11255816Abstract: Devices, systems, and methods of using them are disclosed that position an end of a capillary electrophoresis tube within an internal tapered nozzle region of an inkjet print head or other microfluidic pump. The capillary electrophoresis tube can extend through an inlet of the microfluidic pump and leave space for a sheath liquid to enter the pump and mix with separated analytes eluted from the capillary electrophoresis tube. The small volume of mixed sheath liquid and analyte can then be jetted through the nozzle at a moving surface, either continuously or as discrete droplets. Relative positions on the surface can indicate separation distances of dispensed analytes.Type: GrantFiled: April 28, 2020Date of Patent: February 22, 2022Assignee: LI-COR, Inc.Inventors: Michael D. Furtaw, Donald T. Lamb