Abstract: A medical syringe having a forwardly projecting needle that is selectively retractable following use and also having a specially configured plunger handle and thumb cap that cooperate to form a concave pressure application surface (“CPAS”). The concave pressure application surface at the rear of the plunger handle enables the subject medical syringe to achieve functional advantages, each with an associated therapeutic benefit, that are not achieved with use of the prior art devices.

Abstract: A delivery system for delivering a drug depot to a site within a patient, the system comprising: a cannula; a delivery stylet configured and dimensioned to be receivable by and slidable forwardly and backwardly within the cannula including to a position wherein a distal portion of the stylet protrudes beyond the distal end of the cannula; a drug depot retainable by the stylet at the distal end of the stylet, the drug depot being visualizable by a diagnostic imaging beam or modality; and an actuator for ejecting the drug depot from the stylet to a site within the body using fluid pressure. Also disclosed are methods using, and uses of, the delivery system, including for treating scoliosis.

Abstract: A Luer-lock fastening needle hub is proposed. The Luer-lock fastening needle hub has an insertion groove for a front end of a tapered tube of a barrel to receive the tapered tube into which a plunger is inserted, so that a plunger contact surface is inserted into the tapered tube of a front discharge end of the barrel. The Luer-lock fastening needle hub has a needle cap fastening grooves formed along an outer circumference thereof and “V”-shaped insertion guides are formed in four direction at front portions of openings of the needle cap fastening grooves, so that fastening protrusions formed on an inner surface of a needle cap are unaffectedly guided by the “V”-shaped insertion guides and are easily aligned and fastened to the needle cap fastening grooves.

Abstract: A device for injecting a medicament is provided. The device has a housing with a container within it which can hold a medicament. At its proximal end the container has a needle and a stopper. The device includes a plunger which at one end can engage the stopper. At the opposite end, the plunger can engage a first resilient member to move the stopper within the container to inject the medicament from the container. The device includes a collar with distal and proximal ends, the distal end engaging with a carriage and causing its rotation and the proximal end engaging with a second resilient member. The second resilient member can engage with a skin sensor which has distal and proximal ends. At the proximal end, the skin sensor can contact an injection site. The housing has a cap which can reduce or prevent movement of the skin sensor.

Abstract: The present invention provides a liquid dispensing device made of non-plastic material for its use to squirt liquid through a nozzle of the device. The non-disposable device is an environmentally friendly and health safe alternative to conventional plastic bottles used by millions of people suffering from allergies for nasal irrigation. The device comprises a main body structure including a plunger disc, a push button operation mechanism, a container, and a nozzle. The container is detachable from the main body so it can be filled with water and warmed up in a microwave oven. When the button is pushed to plunge the disc into the container, warm water is squirted through the nozzle into a nasal opening.

Abstract: A needle-based device includes a barrel as a body thereof and a needle. A portion of the needle is received within the barrel and glued thereinto to cause the needle to protrude from the barrel. The needle-based device also includes a needle shield to protect an entire length of the needle protruding from the barrel based on completely encompassing the entire protruding length of the needle in a first state of disuse of the needle-based device. The barrel includes wings on lateral sides of an outer wall thereof. The wings extend perpendicular to a length of the barrel to couple the needle shield to the barrel in the first state of disuse of the needle-based device.

Abstract: Drug delivery devices are provided in which much of a drug payload within the device remains within an area proximal to a wall of the device through which the drug must pass for release of the drug from the device into a patient. In one case, the device may include a drug reservoir portion which has a drug reservoir lumen bounded by a reservoir wall having an inner surface; a drug located in the drug reservoir lumen; and a core region which does not comprise the drug, wherein the drug is disposed between the inner surface of the reservoir wall and the core region. The device may be elastically deformable between a first shape suited for insertion through a lumen into a body cavity of the patient and a second shape suited to retain the device within the body cavity.

Abstract: The present disclosure provides a new and innovative method and system for flow rate compensation in devices, such as infusion pumps. In various embodiments, a computer-implemented method includes determining a location of a plurality of infusion pumps in a pump stack including the plurality of infusion pumps and a fluid supply connected to each of the plurality of infusion pumps. The computer-implemented method also includes determining a reference infusion pump, in the plurality of infusion pumps, and adjusting the flow rate for each infusion pump in the plurality of infusion pumps based on the distance between the infusion pump and the reference infusion pump.

Abstract: Provided is an enema nozzle for an enema device. Said enema nozzle includes an insertion body with a flexible insertion tip. The flexible insertion tip is located at the insertion end of the insertion body, and said tip will flex when it abuts intestinal tissue. This will provide a smoother insertion, which effectively will alleviate the physical discomfort and pain that a patient may expire during insertion of an enema nozzle.

Abstract: An apparatus for use in injectate delivery includes an actuator including a linkage, a force generating mechanism mechanically coupled to the linkage, and a controller coupled to the force generating mechanism. The force generating mechanism includes a passive force generator and an active force generator. In operation and on the basis of a control signal, the controller is configured to control the force generating mechanism to provide an input force to the linkage that is a combination of the first force provided by the passive force generator and a second force provided by the active force generator.

Abstract: Disclosed is an irrigation system. The irrigation system includes a manual pump. The manual pump can provide pressurized liquid through a tube at an outlet.

Abstract: A fluid delivery apparatus comprises a first piston body, a second piston body, a fluid delivery pipe, and a sealing element. The first piston body has a first through hole, a first connecting portion, an accommodation space and a buffer space. The second piston body has a second through hole and a second connecting portion disposed inside the accommodation space. The fluid delivery pipe is accommodated in the first through hole and the second through hole, and movable between a first position and a second position. The sealing element encircles the fluid delivery pipe. When the fluid delivery pipe is at the first position, the sealing element is accommodated in the accommodation space. When the fluid delivery pipe is at the second position, a first part of the sealing element is accommodated in the accommodation space, and a second part of the sealing element is accommodated in the buffer space.

Abstract: A venous access port assembly having a base, a peripheral surface, and a septum. The base defines an interior reservoir. The peripheral surface includes integrally molded X-ray discernable indicia identifying that the assembly is rated for power injection. The X-ray discernable indicia may extend through a height of the peripheral surface from a top surface to a bottom surface thereof. According to one aspect, the peripheral surface may be formed from X-ray discernable material, and the X-ray discernable indicia may be formed from the X-ray discernable material, or they may be formed by voids in the X-ray discernable material. According to another aspect, the peripheral surface may be formed from a radiotransparent or radiolucent material and applied with a radiopaque agent, and the X-ray discernable indicia may be one or more voids in the radiopaque agent or may be portions of the peripheral surface applied with the radiopaque agent.

Abstract: The present invention relates to a self-retaining enema nozzle (1,1?,1?,1??) and an enema system (34) comprising said enema nozzle. The enema nozzle (1,1?,1?,1??) comprises a catheter (2) provided with a retention member (3) arranged for being placed in a compact form during insertion in a body cavity and for being placed in an expanded form for retaining the enema nozzle in said body cavity, and wherein the enema nozzle (1,1?,1?,1??) further comprises a restriction unit (4) arranged for placing the retention member (3) in its compact form. Since the restriction unit (4) holds, e.g. keeps, places and/or maintains the retention member (3) in the compact form both before and during insertion, any discomfort and/or harm that may be experienced using the conventional enema nozzles/devices is effectively prevented.

Abstract: A disposable cartridge for a drug delivery device includes a flexible bag to accommodate a liquid medicament and having an opening adjacent to a sidewall, a socket having a fluid channel in fluid communication with a cartridge fluid coupling, and a housing covering at least a portion of the flexible bag and having a receptacle to receive the socket with the flexible bag. The socket extends into the opening of the flexible bag. The flexible bag's sidewall is fixed between the socket and the receptacle.

Abstract: Devices and methods for extracting and concentrating therapeutically active factors from mammalian fluids and tissues are described herein.

Abstract: A method includes protecting an entire length of a needle of a needle-based device protruding from a needle mount or a body of the needle-based device in a first state of disuse thereof based on providing a needle shield encompassing the entire protruding length of the needle, and encompassing the needle shield completely in the first state of disuse with an external cap. The method also includes providing a guide element protruding inward from an end of the external cap farthest away from the needle mount or the body of the needle-based device, internal to the external cap parallel to a length of the external cap and through the needle shield such that, in the state of disuse, the guide element at least partially envelops the needle therewithin to prevent significant lateral movement of the needle and prevents the end of the external cap from touching the needle.

Abstract: A system for injecting includes a syringe body, a syringe interior, a syringe flange, and a stopper member and an injectable fluid disposed in the syringe interior. The system also includes a plunger member coupled to the stopper member. The system further includes a finger flange removably coupled to the syringe flange, the finger flange defining a pair of side openings and a pair of bumps adjacent respective side openings. Moreover, the system also includes a swing spacer rotatably coupled to the finger flange, the swing spacer defining a pair of arms, a pair of pivot pins, two pairs of slots, and a pair of indentations. The swing spacer is configured to define a distance of movement of the plunger member relative to the syringe body along a longitudinal axis of the syringe body, thereby defining a dose of the injectable fluid.

Abstract: An injector includes a body, an injection needle movably mounted to the body and a pathway within the body sized for receiving either of a first cartridge or a differently dimensioned second cartridge therein. The pathway includes a coupler mounted at a distal end that is engageable with the first cartridge or the second cartridge for to fluidly connect with the injection needle. At least two adapter collars are mounted within the pathway. A first adapter collar is configured to receive either one of the two cartridges therethrough upon insertion into the pathway, and configured to engage a portion of the first cartridge to stabilize the first cartridge within the pathway. A second adapter collar is also configured to receive either one of the two cartridges therethrough upon insertion into the pathway, but configured to engage a portion of the second cartridge to stabilize the second cartridge within the pathway.

Abstract: A syringe with structural features to accomplish one-handed aspiration as well as one-handed injection. The syringe includes one or more breaking points that are configured to break at predetermined locations in response to external forces being applied thereto. To assist in accountability, identification chips and/or codes are included to allow for the traceability of the syringe to potential sources of irresponsible dispensing of medical waste.