Abstract: A balloon catheter includes an inner shaft with a distal variant portion and a proximal variant portion. A bulged portion is provided at the distal end of a reinforcement member, and the bulged portion is configured to move in an axial direction between the distal variant portion and the proximal variant portion. Thus, the balloon catheter may smoothly pass through a curved blood vessel with improved kink resistance of the reinforcement member.

Abstract: An ophthalmic infusion support and associated methods are shown. Example infusion support devices include a base region, a support region, and a fastener. The fastener may take on the form of a c-shaped clip. When in use, the ophthalmic infusion support holds an infusion tube at an angle projecting away from a patient's eye.

Abstract: A medical infusion pump can be configured to sequentially inject solutions from multiple syringes. The medical infusion pump can be configured to automatically sequence the injection either by creating differential fluid pressures during injection or by employing a sequencer that creates differential forces on poppets which form seals between different input ports of the sequencer.

Abstract: A vascular access site management system includes a stabilization body and a flow housing that is rotatable relative to the stabilization body. The flow housing may have a flow path extending through it to allow fluids to be introduced into or extracted from a patient via a catheter connected to the vascular access site management system. The vascular access site management system may also include a needle free connector fluidly connected to the flow housing via a section of tubing.

Abstract: An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.

Abstract: An apparatus includes a body and a pair of rigid legs extending from the body. The body includes an engagement feature configured to engage a deployment instrument. The legs are parallel with each other. Each leg has a sharp tip. The legs both extend along a plane. The body defines a guide opening. The guide opening is oriented transversely relative to the plane associated with the legs. The guide opening is sized to receive a cannula having a generally flat profile. The guide opening is configured to guide the cannula through a sclerotomy at a substantially tangential orientation.

Abstract: Drug delivery devices are provided in which much of a drug payload within the device remains within an area proximal to a wall of the device through which the drug must pass for release of the drug from the device into a patient. In one case, the device may include a drug reservoir portion which has a drug reservoir lumen bounded by a reservoir wall having an inner surface; a drug located in the drug reservoir lumen; and a core region which does not comprise the drug, wherein the drug is disposed between the inner surface of the reservoir wall and the core region. The device may be elastically deformable between a first shape suited for insertion through a lumen into a body cavity of the patient and a second shape suited to retain the device within the body cavity.

Abstract: A probe may be inserted into a body cavity to perform diagnostic intervention(s), therapeutic intervention(s), or both. The probe may be inserted through a body aperture that is naturally occurring or man-made, intentionally or by accident. The body aperture may form a seal encircling the probe so that insufflation retention material may be effectively retained in the body cavity so that an operator can perform the intervention(s). However, there may be leakage of the insufflation material. The insufflation retention device is configured to form an effective seal contactingly adjacent the body aperture and to provide a passageway for the introduction of the probe into the body cavity, such that a diagnostic intervention or therapeutic intervention or both may be performed.

Abstract: An auto-injector having a body (1) receiving a reservoir (S) and including a piston (P); a piston rod (5) movable between a primed position and an injection position in which the piston rod (5) has moved the piston (P) to inject fluid into an injection site; and a visual, audible, and/or tactile indicator device for indicating that the autoinjector may be removed from the injection site. The autoinjector includes a retarding system to delay actuating the indicator device relative to the end of injection and that includes a dashpot (16), a shear member (19) and a fluid. The dashpot or the shear member is rotatably mounted in the body and the other is stationary in rotation, the turning of one relative to the other being braked by shearing the fluid contained in the dashpot. The dashpot and shear member include projections that impede the flow of the fluid.

Abstract: An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

Abstract: A patch injector (10) for parenteral administration of a drug to a drug recipient has a drug-cartridge module (14) attached to a power-pack module (12) and to a drug-recipient interface module (16). A compressed, elastic power element (18) disposed in the power-pack module (12) is coupled to a plunger (30) movably disposed in a drug reservoir (22) in the drug-cartridge module (14). An injection needle (24) at the distal end of the drug reservoir (22) is oriented orthogonal to the drug reservoir (22) and generally toward a skin-contact surface (28) extending parallel to the longitudinal drug-reservoir axis (22A). The power element (18) is configured to displace the plunger (20) distally into the drug reservoir (22) and to move the injection needle (24) toward the skin-contact surface (28) when the power element (18) expands distally along the drug-reservoir axis (22A).

Abstract: A drive mechanism (4) for a drug delivery device comprising—a piston rod (14), —a trigger member (9) coupled with the piston rod (14) in such a manner that rotational movement between the piston rod (14) and the trigger member (9) is constrained in a first state, the trigger member (9) being elastically deformable in such a manner that the piston rod (14) is rotationally moveable with respect to the trigger member (9) in a second state, —a trigger button (10) being suitable for activating the deformation of the trigger member (9).

Abstract: A method of reshaping a body part including the step of injecting a quantity of filler material into a subperiosteal plane of a facial region thereby depositing a body of filler between the periosteum and bone of the facial region. The method includes the step of piercing a periosteum of the facial region with a syringe. The method includes the step of drawing backwards a plunger of the syringe to ascertain whether a tip of a needle of the syringe is within a blood vessel. The filler may include a hyaluronic acid gel. The method of reshaping a body part includes the step of applying pressure to the body of filler to adjust a shape of the body of filler. The step of injecting is repeated in the following order of priority: first the temporal line of fusion, second the zygoma, third the malar, and fourth the jaw line.

Abstract: Aspects of the present disclosure provide systems, devices, and methods for delivering substances such as fluids, solutions, medications, and drugs to patients using infusion devices having a set of advanced features. These advanced features include aspects related to the programming of infusion devices, the configuration of infusion sequences performed by the infusion devices, and the interconnection of multiple infusion devices for interoperation during an infusion having a sequence of infusion steps.

Abstract: A drive assembly for a drug delivery device includes a spring member, a piston rod and a piston rod nut being engaged with the piston rod. The piston rod nut is configured to rotate and axially move during dose setting. The spring member is compressed when the piston rod nut is moved during the dose setting. The piston rod nut is rotationally fixed during dose dispensing.

Abstract: Disclosed is a puncture depth controlling and needle hiding device and a usage method thereof. The puncture depth controlling and needle hiding device comprises a housing and an inner sleeve. The inner sleeve is positioned in the housing and is rotatable. Correspondingly matched limiting structures are provided on an inner wall of the housing and an outer wall of the inner sleeve. A spring is provided between the housing and the inner sleeve to push the proximal ends of the housing and the inner sleeve to be separated and keep the inner sleeve at an initial axial position with respect to the housing. By means of the invention, the medicinal liquid injection operation is simplified, and the need insertion depth is accurate. A needle hiding structure reduces the risk of accidental stab.

Abstract: A device for an injection needle that enables reuse of a single-use injection needle for multiple injection uses for a same user is described. The device has a needle cover with a disinfecting agent, a sanitizing agent and a lubricating agent that are positioned inside the needle cover. The needle cover sanitizes, disinfects and lubricates a single-use injection needle for reuse when the needle is moved inside the needle cover and positioned therein for temporary storage. The agents are held in a medium that enable the agents to be positioned inside the needle cover. The agents in the medium are stacked on top of each other in heights for different needle lengths. The first stack is a wick medium that absorbs excess fluid droplets from a needle head, the second stack is a medium that disinfects the needle, and the third stack is a medium that lubricates the needle.

Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.

Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.

Abstract: Ambulatory infusion pumps, medicament reservoirs, and plungers, including both dynamic and static seals, plus related components, as well as component combinations and related methods.