Abstract: An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication.

Abstract: A safety syringe extension adapter and an applicator unit having at least one applicator is disclosed. More particularly, an applicator unit is connected to a syringe by a safety syringe extension adapter and including an applicator wherein the applicator unit comprises pivotal movement relative thereto about two separate pivot axes for following the skin contours of a user during certain skin related procedures such as applying Platelet Rich Plasma (PRP) to the skin; applying a chemical peel to the skin using Trichloracetic Acid (TCA), glycolic acid (GA), or any fluid for purposes of applying to the skin; applying antiseptics to sterilize the skin prior to or after a procedure; or applying analgesics to the skin surface or any other fluid to the skin surface.

Abstract: Improvements in an infusion unit are disclosed. The infusion unit is a portable pump that can be used with patient that have wrist access or decubital PICC/MID-LINES without the risk of line accidently getting pulled. The infusion unit is in the shape of a conveniently shell that has an appearance of an arm cast. There are no hoses that extend beyond the body of the infusion unit and any vein penetration is completely covered under the body of the infusion unit. The secure enclosed unit prevents unauthorized tampering and entry into the unit. The medication dosing can be remotely monitored, fusion resumed, changed by nursing and the patient. The infusion unit has a wireless connection to a network to adjust medication and monitor vital signs, namely heart rate, O2 level and blood pressure that can be monitored and recorded for review.

Abstract: Systems and methods for selective auto-retroperfusion along with regional mild hypothermia.

Abstract: A catheter system having one or more needle position indicators to assist an operator in withdrawing the introducer needle to a “parked” position, as part of a catheterization procedure, wherein the needle position indicator provides a visual indication to the operator.

Abstract: An infusion device (1) for administering a medical fluid to a patient (P) comprises a pump mechanism (11) for administering a medical fluid to a patient (P) through a line set (3), a sensor device (14) for measuring a measurement value indicative of a pressure in the line set (3), and a processor device (15) configured to automatically set, in an initial phase, a threshold value (15) to a value determined based on at least a mechanical characteristic of the line set (3) and/or the pump mechanism (11) and to determine, in an operational phase, whether an occlusion condition in the line set (3) is present based on the measurement value and the threshold value (Pthres) —Herein, the processor device (15) is configured to adjust the threshold value (Pthres) if in the operational phase a pressure variation condition in the line set (3) different than an occlusion condition is detected by the processor device (15).

Abstract: A portable insulin pump can utilize readings from a sensor incorporated into an infusion set used with the pump to deliver insulin to a patient to determine if the infusion set is or is likely to become dislodged from the patient. Readings from the sensor that are inconsistent with expected readings or a range of expected readings can indicate that the infusion set has become dislodged from the patient.

Abstract: An injection device comprising a cap for removing a needle protection cap from a product container, and a method for assembling an injection device. The cap comprises an engaging element for removing the needle protection cap from the product container when the cap is removed from the injection device. The engaging element can be deformed in such a way that the engaging element can be moved from a distanced position, in which the engaging element is radially distanced from the needle protection cap, into an engagement position, in which the engaging element engages with the needle protection cap, with the engaging element being deformed when the cap is removed.

Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end, operate the syringe to supply the dose of medicament, and retract the syringe with the needle after delivering the medicament. An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: Various implementations include a tissue lifting device that is operable using one hand. The device includes a housing, an actuator that is slidably moveable through a channel within the housing, and a lifting mechanism adjacent a distal end of the housing. The actuator causes the lifting mechanism to lift a tissue. In some implementations, the housing includes a needle adjacent the distal end of the housing that punctures the tissue and allows for injection of a composition behind the tissue. The lifting mechanism according to some implementations is a suction-based (or aspiration) system. And, in other implementations, the lifting mechanism is a grasping system.

Abstract: An insertion/retraction mechanism for a drug delivery device is disclosed. The insertion/retraction mechanism includes a retraction hub, an insertion hub, an insertion/retraction mechanism housing, and a dual torsion spring system. The retraction hub includes a first primary rotational stop and a second primary rotational stop extending radially inwardly from an inside surface. The insertion hub is disposed inside the retraction hub and comprises a first complementary rotational stop and a second complementary rotational stop extending radially outwardly from an outside surface.

Abstract: Some embodiments are directed to a needle assembly including at least N injection needles where N is at least four and a multiple of two. The needle assembly also includes a first liquid port adapted to be connected to an injection device, and N second liquid ports connected to one of the N injection needles. N/2 main liquid pathways each have an entrance connected to the first liquid port and an exit, further including N/2 secondary liquid pathways that have two extremities each opening on one of the N second liquid ports, and a mid portion connected to the exit of one of the main liquid pathways. The main liquid pathways and the secondary liquid pathways define N liquid flow paths between the first liquid port and the N second liquid ports dimensioned so a pressure drop between them is similar.

Abstract: A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.

Abstract: A catheter devices/systems and methods therefrom are described herein for treating acute kidney injury, especially the contrast-induced acute kidney injury wherein the devices prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

Abstract: The disclosure is directed to a device for electroporating and delivering one or more antigens and a method of electroporating and delivering one or more antigens to cells of epidermal tissues using the device. The device comprises a housing, a plurality of electrode arrays projecting from the housing, each electrode array including at least one electrode, a pulse generator electrically coupled to the electrodes, a programmable microcontroller electrically coupled to the pulse generator, and an electrical power source coupled to the pulse generator and the microcontroller. The electrode arrays define spatially separate sites.

Abstract: The embodiments disclosed herein relate to catheter assemblies. The catheter assemblies can include a multi-lumen catheter, a junction hub, and extension legs. The catheter assemblies can also include a sheath that includes a membrane that is permeable to one or more gases and impermeable to one or more liquids or solids. The catheter assemblies can be configured to deliver food to a patient through a first lumen, and simultaneously vent or aspirate one or more gases from the patient through a second lumen. The catheter assemblies can also include preformed catheters that assume a non-linear three-dimensional shape when in a relaxed state.

Abstract: Methods and devices related to the fields of skin care, hair restoration and lip care wherein the systems may be used by an individual for infusing treatment media into skin or lips for cosmetic and rejuvenation purposes, hair restoration purposes or other therapeutic purposes.

Abstract: A medical wetness sensing device includes a cover, a first and second electrically conductive portions housed in the cover, an electrically insulative portion housed in the cover, and a compressible portion. The cover defines an outer surface. The first and second electrically conductive portions are exposed along an inner surface of the device. The first and second electrically conductive portions are configured to transmit a test signal indicating an absence or presence of a liquid on the inner surface. The electrically insulative portion electrically isolates the first electrically conductive portion from the second electrically conductive portion. The compressible portion is flexible, compressible, and configured such that the inner surface of the device is conformable to skin of a wearer of the device. The compressible portion is formed by at least one of the cover, the first and second electrically conductive portions, and the electrically insulative portion.

Abstract: A medicament container holder for securing a medicament container having a generally tubular body arranged with a proximally directed neck portion and a flange portion arranged with a pierceable septum. The medicament container holder has mechanical holding elements that interact with the flange portion for preventing movement of the medicament container in a distal direction and having mechanical fixation elements configured to interact with the flange portion for urging the flange portion in the distal direction against the holding elements, where the medicament container holder has attachment elements for a medicament delivery member. The mechanical fixation elements are configured to engage with the medicament delivery member when attached to the attachment elements, such as to exert a force in the distal direction on said flange portion.

Abstract: A connector retains a medicine reservoir in a housing. The connector snaps onto the reservoir, the connector and reservoir are inserted into an aperture in the housing, and the connector snaps into the aperture in the housing. The connector may have a tubing and needle fixed in it to insert into the reservoir. The connector does not require a particular orientation when snapped into the housing and some embodiments may rotate freely. When snapped into the housing, the connector provides an auditory cue. For removal of the connector and reservoir, the exposed portion of the connector is compressed from the side. The configuration of the connector solves several problems associated with threaded connectors or other similar connectors.