Abstract: The invention relates to processes for the synthesis of aryl or alkene borates which comprises reacting: (i) an olefinic compound having a halogen or halogen-like substituent in a vinylic substitution position, or (ii) an aromatic ring having a halogen or halogen-like substituent in a ring substitution position, with a disubstituted monohydroborane in the presence of a Group 8-11 metal catalyst. The invention also relates to the use of these borates in coupling reactions. The invention further relates to certain disubstituted monohydroboranes and aryl or alkene borates.

Abstract: A carborane supercluster consisting of carborane (C2B10H12) as its constituent unit expressed as a molecular formula C2mB10mH12m-x, where x is a positive integer (i.e., x=1, 2, 3, . . . ) and m is an integer greater than unity (i.e., m=2, 3, . . . ). The parameter x represents the count of removed or detached hydrogen atoms. The parameter a represents the count of the clusters linked together. To produce the supercluster, carborane (C2B10H12) is ionized in a reaction chamber to generate carborane ions and then, the carborane ions thus generated are successively reacted with the remaining neutral (i.e., non-ionized) carborane (C2B10H12), thereby generating the carborane supercluster. Preferably, the cluster of the carborane consists of at least two of o-carborane, m-carborane, and p-carborane.

Abstract: The conventional process for the production of a peracetic acid product, wherein hydrogen peroxide, acetic acid and water are fed into an aqueous reaction medium containing hydrogen peroxide, acetic acid, peracetic acid and an acid catalyst, wherein hydrogen peroxide and acetic acid react in the presence of the acid catalyst and form peracetic acid, and an aqueous peracetic acid concentrate is removed continuously from the reaction medium by distillation, has now been improved by feeding the acid catalyst continuously into the reaction medium and by withdrawing continuously a portion of the reaction medium as a bottom product. When the through flow of the reaction medium is thus increased, it is purified of impurities threatening the safety of the process. If the amount of acid catalyst in the reaction medium is further decreased, a product suitable, for example, for disinfection is obtained from the bottom product.

Abstract: The reaction medium and distillate of a conventional continuous peracetic acid process can be combined into a stable peracetic acid product if the acid catalyst present in the reaction medium is neutralized.

Abstract: Processes for making particularly branched, especially monomethyl-branched or nongeminal dimethyl-branched surfactants used in cleaning products; preferred processes comprising particular combinations of two or more adsorptive separation steps and, more preferably, particular alkylation steps; products of such processes, including certain modified alkylbenzenes, modified alkylbenzenesulfonate surfactants, and consumer cleaning products, especially laundry detergents, containing them. Preferred processes herein more specifically use specific, unconventional sequences of sorptive separation steps to secure certain branched hydrocarbon fractions which are used in further process steps as alkylating agents for arenes or for other useful surfactant-making purposes. Surprisingly, such fractions can even be derived from effluents from current linear alkylbenzene manufacture.

Abstract: Polysubstituted indan-1-ol compounds, methods for their preparation; and methods for their use are disclosed herein. In particular, the invention relates to polysubstituted indan-1-ol compounds of the formula I and their physiologically acceptable salts. The compounds are useful, for example, as anorectics.

Abstract: The present invention is directed to a fast-acting, aqueous phase chemical treatment for reducing the emission of hydrogen sulfide odor from an aqueous medium, e.g., a wastewater or pulping and paper making medium, to the vapor phase. This invention comprises adding an effective amount for the purpose of glyoxal to the desired hydrogen sulfide-containing medium.

Abstract: Derivatives of C2-substituted indan-1-ol compounds of the formula I: its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of obesity are disclosed herein. Compositions comprising the same, methods for preparing the instant compounds, and methods for reducing weight in mammals and for the prophylaxis or treatment of obesity are also described.

Abstract: This invention relates to a process for the production of an aryl thiol, which comprises hydrogenating an aryl sulfonyl chloride in a solvent in the presence of a palladium catalyst and a base whose conjugate acid has a pKa of about 2 or greater, wherein the base is selected from the group consisting of ionic bases soluble in water and tertiary amines soluble in the solvent, the tertiary amines not having a methyl group attached to the amine nitrogen.

Abstract: The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as anti-tumor 5 agents which effectively inhibit the growth of mammalian cells.

Abstract: The present invention provides a novel salt useful as an active species in an organic reaction and represented by the following chemical formula (1): wherein n stands for an integer of from 1 to 8, Zn− represents an n-valent anion of an active hydrogen compound, a, b, c and d each stands for a positive integer, and Rs represent the same or different hydrocarbon groups. Also disclosed is a simple and efficient process for producing a poly(alkylene oxide) by polymerizing an alkylene oxide compound in the presence of the salt represented by the chemical formula (1).

Abstract: New boron icosahedral ethers and esters formed from Cs2[closo-B12(OH)12],; Cs[closo-1-H-1-CB11(OH)11]; and closo-1,12-H2-1,12-C2B10(OH)10 are disclosed. Also set forth are their preparation by reacting the icosahedral boranes [closo-B12H12]2−, [closo-1-CB11H12]− and closo-1,12-(CH2OH)2-1,12-C2B10H10 with an acid anhdride or acid chloride to form the ester or an alkylating agent to form the ether.

Abstract: This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).

Abstract: There are disclosed a disulfone compound of formula (1): wherein Ar denotes an aryl group that may have a substituent, R1 denotes a hydrogen atom or a protective group of a hydroxyl group and the wavy line means that the disulfone compound is an E or Z geometrical isomer or a mixture thereof, a method for producing the same, intermediate compounds therefore and a process for producing retinol through the disulfone compound.

Abstract: The present invention provides a process for the preparation of highly pure 2-Methyl-2-propene-1-sulfonic acid, sodium salt in high yield, with very low iron content, by the reaction of distilled sulfur trioxide complexed with a Lewis base in a halogentated solvent, the unreacted sulfur trioxide vapors being removed from the reactor before the mixture is treated with liquefied isobutylene, and neutralization by a base with an iron content within the range of 0 to 20 ppm.

Abstract: Embodiments of the invention relate to C2-substituted indan-1-ols and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention may include compounds of formula I in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable, for example, for use as anorectics.

Abstract: The invention relates to a method of preparing lithium complex salts and their intermediaries and to the use of these in electrolytes.

Abstract: The invention relates to new calixarenes according to the formula: wherein: R1 is an alkyl or aryl group, or a hydrogen atom, R2 and R3, which may be identical or different, are alkyl or aryl groups, n is an integer ranging from 2 to 8, and p is an integer ranging from 4 to 8. Said calixarenes may be used to extract actinides and lanthanides from aqueous solutions.

Abstract: A process for the preparation of salts of substituted or unsubstituted methylene bisphosphonic acids by hydrolysing the corresponding acid ester with hydrochloric acid, removing water from the acid azeotropically prior to addition of an amine or a base to produce the resultant salt in good yield.

Abstract: 3,3′-Substituted chiral biaryl phosphine and phosphinite ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes are useful as catalysts in asymmetric reactions, such as, hydrogenation, hydride transfer, allylic alkylation, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, olefin metathesis, hydrocarboxylation, isomerization, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition, epoxidation, kinetic resolution and [m+n] cycloaddition. The metal complexes are particularly effective in Ru-catalyzed asymmetric hydrogenation of beta-ketoesters to beta-hydroxyesters and Ru-catalyzed asymmetric hydrogenation of enamides to beta amino acids.