Patents Examined by Jeffrey T Palenik
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Patent number: 11553718Abstract: The invention relates to a process for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation. The invention further relates to the use of a water soluble source of lithium ions for reducing the minimum inhibitory concentration (MIC) of a biocide against at least one strain of bacteria and/or at least one strain of yeast and/or at least one strain of mould in an aqueous preparation.Type: GrantFiled: July 8, 2020Date of Patent: January 17, 2023Assignee: Omya International AGInventors: Anita Zumsteg, Joachim Glaubitz, Simon Urwyler, Matthias Buri, Patrick A. C. Gane
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Patent number: 11541129Abstract: Disclosed herein are biomaterial implants, medical devices, or bioprostheses wherein a surface or part thereof is coated with a nanoreservoir comprising a hydrophilic polymer or copolymer backbone crosslinked to a second polymer comprising a hydrophilic backbone and one or more reactive moieties, wherein the nanoreservoir further comprises one or more bioactive molecules, therapeutic molecules, or drugs.Type: GrantFiled: December 28, 2017Date of Patent: January 3, 2023Assignee: UNIVERSITÉ DE LIÈGEInventors: Cécile Oury, Christine Jérôme, Christophe Detrembleur, Patrizio Lancellotti
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Patent number: 11534395Abstract: A suspension includes an ophthalmic active ingredient suspended in a formulation vehicle including a suspending agent and a non-ionic cellulose derivative. The ophthalmic active agent is present as particles having Dv90<5 ?m and Dv50<1 ?m. The suspension may be administered to a patient for treating an ophthalmic inflammatory condition.Type: GrantFiled: March 23, 2020Date of Patent: December 27, 2022Assignee: Bausch & Lomb IncorporatedInventors: Mohannad Shawer, Eric Phillips, Martin J. Coffey
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Patent number: 11523986Abstract: Disclosed herein are compositions including diphenhydramine, or a pharmaceutically acceptable salt thereof, and a liquid vehicle. The compositions may be administered intranasally to patients in need of diphenhydramine. The compositions provide increase plasma and brain concentrations relative to orally administered compositions, but without the limitations associated with intravenously administered compositions.Type: GrantFiled: March 19, 2020Date of Patent: December 13, 2022Assignee: DBBH, LLCInventors: John Sramek, Anthony R. DiSanto
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Patent number: 11517519Abstract: The present invention relates to a process for treating human keratin fibres such as the hair, which comprises: i) a step of applying to the human keratin fibres a composition comprising: —at least one plant wax: —at least 60% by weight of water relative to the total weight of the composition; ii) followed by a step of heating the keratin fibres by means of a heating appliance at a temperature ranging from 80° C. to 160° C., preferably from 110° C. to 50° C., more preferably from 120° C. to 150° C., which is moved along the fibres, iii) optionally followed by a step of rinsing the keratin fibres.Type: GrantFiled: June 6, 2017Date of Patent: December 6, 2022Assignee: L'OREALInventors: Eric Parris, Gabin Vic, Frédéric Woodland
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Patent number: 11517562Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: June 1, 2022Date of Patent: December 6, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Patent number: 11504336Abstract: An extended release pharmaceutical composition of Clozapine The extended release composition of Clozapine provides an extended release pharmaceutical composition having Clozapine, a seal coating, an acidic coating, and an extended release coating. The composition is particularly suitable for dispensing a once-a-day solid oral pharmaceutical formulation which releases a therapeutically effective amount of Clozapine over an extended time period.Type: GrantFiled: September 16, 2017Date of Patent: November 22, 2022Assignee: INTAS PHARMACEUTICALS LTD.Inventors: Mayank Saxena, Rikin Patel, Piyush Kansagra, Balvir Singh, Ashish Sehgal
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Patent number: 11497940Abstract: Method for treating hair comprising the successive application onto hair of polymeric layers which can be removed to a large extent or even totally in an easy manner upon request of the user by using a cationic surfactant.Type: GrantFiled: April 25, 2017Date of Patent: November 15, 2022Assignee: WELLA OPERATIONS US, LLCInventors: Lars Siegfried Dahne, Mathias Kurt Herrlein, Stephen Robert Schofield, Cagri Uzum, Natascha Katharina Schelero
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Patent number: 11458096Abstract: Exemplary embodiment of the present disclosure are directed towards a stable nanodispersion comprising an aqueous dispersion medium, a dispersed phase, a surface active agent and optionally, an additive, wherein the aqueous dispersion medium comprises of a nanodispersion stabilizing vehicle base component, wherein the nanodispersion stabilizing vehicle base component improves long term physical stability of the nanodispersion with or without particle size reduction, wherein the dispersed phase comprises of a bioactive compound and wherein the bioactive compound is a lipophilic and hydrophobic. Another exemplary embodiment of the present disclosure is directed towards a method of preparation of such stable nanodispersion.Type: GrantFiled: April 8, 2015Date of Patent: October 4, 2022Assignee: PULSE PHARMACEUTICALS PVT. LTD.Inventors: Rambhau Devraj, Pranati Chhatoi, Naga Hemanth Kumar Parvathabhatla, Anand Vasant Deshmukh, Krishna Kaushik Chintabhatla
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Patent number: 11452676Abstract: The present invention relates to a composition, preferably a cosmetic composition, and more preferably a skin cosmetic composition, comprising: (a) at least one particle, comprising at least one cationic polymer, at least one anionic polymer and at least one non-polymeric base having two or more pKb values or salt(s) thereof; and (b) at least one physiologically acceptable volatile medium. The composition according to the present invention is stable, and can have a variety of cosmetic functions.Type: GrantFiled: June 8, 2018Date of Patent: September 27, 2022Assignee: L'OrealInventors: Toshifumi Shiroya, Hidehiko Asanuma, Takehiko Kasai
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Patent number: 11439617Abstract: The present invention comprises compounds of formula (I): where R1 may be PEG or other polymeric moieties. For example, R1 may be repeating PEG units —(CH2—CH2—O)n—, wherein n=1-455. R1 may also be other polymeric moieties of varying sizes and structures, for example, R1 may be poly(glycolide), poly(lactic acid), poly(lactide), poly(caprolactone), poly(lactide-co-caprolactone), poly(lactide-co-glycolide), or poly(lactic acid)-butanol. One or more embodiments of the invention may also relate to injectable pharmaceutical compositions comprising polymer conjugated monomethyl fumarate, and methods for treating relapsing-remitting multiple sclerosis and psoriasis.Type: GrantFiled: October 16, 2018Date of Patent: September 13, 2022Inventors: Deven Patel, H. Rajan Sharma, Manoj Mishra
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Patent number: 11433136Abstract: Provided herein are polymers, pH-sensitive polymers and/or linkers; conjugates comprising said polymers and/or linkers, optionally, coupled to one or more agents and/or targeting moieties; and particles (e.g., nanoparticles comprising the aforesaid polymers, linkers and/or conjugates), which can be used to enhance the delivery and/or efficacy of one or more agents in a subject.Type: GrantFiled: December 16, 2016Date of Patent: September 6, 2022Assignees: The General Hospital Corporation, Massachusetts Institute of Technology, XTUIT Pharmaceuticals, Inc.Inventors: Peter Blume-Jensen, Donald E. Chickering, III, Paul W. Kopesky, Lawrence A. Reiter, Alan Crane, Robert S. Langer, Rong Tong, Rakesh K. Jain, Vikash Pal Singh Chauhan, Joao Incio, Dai Fukumura
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Patent number: 11433037Abstract: Aspects of the present invention are directed to an oral dosage form comprising a core containing one more active ingredients and a fast-release exterior coating. The fast release exterior coating includes a water soluble polymer; a saccharide or sugar alcohol, or a combination thereof, and a flavoring. The flavoring may be a warming sensate that is released in the oral cavity of the user after inserting the dosage form in his or her mouth.Type: GrantFiled: July 5, 2017Date of Patent: September 6, 2022Assignee: GLAXOSMITHKLINE CONSUMER HEALTHCARE HOLDINGS (US) LLCInventor: Christopher Joseph Pulford
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Patent number: 11426391Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: February 14, 2022Date of Patent: August 30, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Patent number: 11413323Abstract: The invention provides ophthalmic compositions comprising about 0.1 % (w/v) cyclosporine dissolved in 1-(perfluorobutyl)pentane for use in the topical treatment of dry eye disease. The invention further provides kits comprising such compositions for the same use.Type: GrantFiled: April 12, 2021Date of Patent: August 16, 2022Assignee: NOVALIQ GMBHInventors: Chiara Silvana Leo, Sonja Krösser, Thomas Schlüter, Alice Meides
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Patent number: 11400050Abstract: A method is described for producing a dosage form. Also described, are granules and tablets obtained by the method. The use of a surface-reacted calcium carbonate in such a method, a dosage form comprising the granules, the use of the granules, or the tablets and/or capsules, or the dosage form in a pharmaceutical product, a nutraceutical product, an agricultural product, a cosmetic product, a home product, a food product, a packaging product and a personal care product as well as pharmaceutical product, a nutraceutical product, an agricultural product, a cosmetic product, a home product, a food product, a packaging product and a personal care product including such granules, or the tablets and/or capsules, or the dosage form are also described.Type: GrantFiled: June 19, 2017Date of Patent: August 2, 2022Assignee: OMYA INTERNATIONAL AGInventors: Carolina Diaz Quijano, Laura De Miguel, Joachim Schölkopf
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Patent number: 11389379Abstract: The present invention relates to a composition according to the present invention comprises: (a) at least one particle comprising at least one cationic polymer, at least one anionic polymer, and at least one non-polymeric acid having two or more pKa values or salt(s) thereof; and (b) at least one physiologically acceptable volatile medium. The composition according to the present invention is stable, and can have a variety of cosmetic functions. For example, the composition according to the present invention can prepare a film which can have cosmetic effects such as absorbing or adsorbing malodor, changing the appearance of a keratin substrate such as skin, changing the feel to the touch of the keratin substrate, and/or protecting the keratin substrate from, for example, dirt or pollutants.Type: GrantFiled: September 23, 2016Date of Patent: July 19, 2022Assignee: L'OrealInventors: Takehiko Kasai, Toshifumi Shiroya, Hidehiko Asanuma, Ritesh Sinha, Christophe Dumousseaux
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Patent number: 11376243Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: February 14, 2022Date of Patent: July 5, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Patent number: 11369571Abstract: A method is described for producing a dosage form and granules including surface-reacted calcium carbonate. Also described, are tablets and/or capsules obtained by the method. Methods using such a surface-reacted calcium carbonate, and a dosage form comprising the granules are also described. Further, methods of using the granules, or the tablets and/or capsules, or the dosage form in a pharmaceutical product, a nutraceutical product, an agricultural product, a cosmetic product, a home product, a food product, a packaging product and a personal care product are also described. A pharmaceutical product, a nutraceutical product, an agricultural product, a cosmetic product, a home product, a food product, a packaging product and a personal care product including the granules, or the tablets and/or capsules, or the dosage form are also described.Type: GrantFiled: June 14, 2017Date of Patent: June 28, 2022Assignee: OMYA INTERNATIONAL AGInventors: Carolina Diaz Quijano, Laura De Miguel, Joachim Schölkopf
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Patent number: 11369677Abstract: A composition is for use as a medicament. The composition contains nanoparticles, wherein the nanoparticles contain a polymer selected from the group consisting of PLGA, PLA, PGA, PCL and poly(meth)acrylates, or a lipid. Further, the composition may contain nanoparticles made of a polymer selected from PLGA, amino alkyl methacrylate copolymers, methacrylic acid copolymers, methacrylic ester copolymers, and ammonio alkyl methacrylate copolymers.Type: GrantFiled: January 31, 2018Date of Patent: June 28, 2022Inventor: Alf Lamprecht