Patents Examined by Jennifer Wecker
  • Methods to predict risk of and to stratify sarcopenia and NAD deficiency
    Patent number: 11815515
    Abstract: The present invention relates in general to the field of muscle disease. In particular, the invention relates to a method for determining if a subject has sarcopenia or has an increased risk of developing sarcopenia. A method of predicting the responsiveness of said subject to nutritional intervention is also provided.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: November 14, 2023
    Assignees: University of Southampton, Agency for Science, Technology and Research
    Inventors: Jerome Feige, Keith Malcolm Godfrey, Neerja Karnani, Eugenia Migliavacca
  • Colorimetric chemical sensor with enhanced color sensitivity
    Patent number: 11815464
    Abstract: A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a lamellar photonic material having alternating layers of a first polymer layer and a second polymer layer. Each first polymer layer can be a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. The photonic material is configured such that, when an analyte contacts the photonic material and becomes disposed within a cavity of the molecularly imprinted polymer, a refractive property of the photonic material changes, causing a detectable color change in the sensor.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: November 14, 2023
    Assignee: DrinkSavvy, Inc.
    Inventor: Min Hu
  • Method, reagent, and chip for measuring analyte concentration in specimen
    Patent number: 11815448
    Abstract: Provided is a means capable of measuring an analyte concentration with high accuracy without requiring fractionation of a biological component. The present invention relates to a method for measuring an analyte concentration in a specimen, including (1) preparing the specimen, (2) mixing a coloring reagent, an oxidoreductase, and a light-scattering adjustment reagent with the specimen to obtain an analysis sample having substantially the same scattered light as the specimen, and (3) measuring the analyte concentration by using the analysis sample.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: November 14, 2023
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Fumihiko Chai, Takeyuki Moriuchi
  • Adsorption apparatus and chemiluminescence type nitrogen oxide concentration meter
    Patent number: 11815433
    Abstract: An inner diameter of an opening of the flow path is larger than a particle diameter of an adsorbent. Therefore, in a state where the flow path 33 is disposed in the container 31, the adsorbent 40 enters the flow path 33 via the opening 33B of the flow path 33. That is, in the adsorption apparatus, the adsorbent is disposed in a region between a side surface portion of the container and the flow path and inside the flow path. Further, in the adsorption apparatus 3, the air flows the region between the container 31 and the flow path 33 and in the flow path 33. Therefore, when the air is flown into the adsorption apparatus 3, the air can be sufficiently brought into contact with the adsorbent 40, and moisture contained in the air can be sufficiently adsorbed.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: November 14, 2023
    Assignee: SHIMADZU CORPORATION
    Inventors: Norio Ohyagi, Ryo Tanabe
  • Liquid-chemical sterilization system with biological indicator
    Patent number: 11813374
    Abstract: A sterilization system includes a vial, a carrier of microorganisms disposed in the vial, and a fluid management system having an output connectable to the vial for delivering a liquid chemical sterilant and a neutralizer thereto. Additionally, a growth medium may be delivered to the vial such that the vial and growth medium may assessed for a change to a visual characteristic indicative of sterilization inefficacy.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: November 14, 2023
    Inventors: Yan Fang, Prabhakaran Jayabalan, Benjamin M. Fryer
  • Fiber substrate-based fluidic analytical devices and methods of making and using the same
    Patent number: 11813608
    Abstract: Embodiments of fiber substrate-based fluidic device and methods of manufacturing the same are described herein. In one example, a method of manufacturing a fiber substrate-based fluidic device comprises bonding a hydrophobic film that is substantially transparent to a laser beam (e.g., a film that transmits at least 80% of the incident radiant power of the laser beam) to a hydrophilic substrate and ablating the hydrophilic substrate with the laser beam without ablating the hydrophobic film to form one or more fluidly sealed channels in the hydrophilic substrate.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: November 14, 2023
    Assignee: Oregon State University
    Inventors: Vincent Remcho, Saichon Sumantakul
  • Microfluidic system based on active control of flow resistance in microfluidic channels and methods of use thereof
    Patent number: 11806713
    Abstract: The invention relates to a microfluidic system based on active control of flow resistance and balancing pressures in microfluidic channels and an improved method for disposable microfluidic devices and cartridges for use in, but not limited to, in-vitro diagnostics. The microfluidic system and device of the invention does not utilize mechanical moving parts to control the fluid flow and has no external fluidic connection to the instrument or fluidics controller.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: November 7, 2023
    Inventors: Dalibor Hodko, Nives Hodko, Anne-Laure Petit, Ulrich Niemann
  • Oral care compositions and methods of use
    Patent number: 11806416
    Abstract: This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: November 7, 2023
    Assignee: Colgate-Palmolive Company
    Inventors: Lisa Manus, Julia Dreifus
  • Systems, devices, and methods for fluidic processing of biological or chemical samples using flexible fluidic circuits
    Patent number: 11806711
    Abstract: Various fluidic structures are described that may be implemented between two portions of material, at least one of which may be made of a flexible but inelastic material, such as Mylar. Such fluidic circuits may be configured such that applying a clamping pressure zone to such fluidic circuits and then moving the clamping pressure zone along the fluidic circuit and along a particular axis may cause the fluidic circuit to operate in a particular manner, thereby driving fluids contained within the fluidic circuit around the fluidic circuit according to a desired flow sequence.
    Type: Grant
    Filed: January 12, 2022
    Date of Patent: November 7, 2023
    Assignee: Hound Labs, Inc.
    Inventors: Daniel H. Friedman, Michael V. D'Ambrosio, William Welch, Thu M. Nguyen
  • Air sterilizing device
    Patent number: 11806450
    Abstract: An air sterilizing device, comprising: a housing (100), forming an air flow path thereon; an ozone generating unit (200), generating ozone particles to be supplied to the air flow path; a filter cartridge (300), receiving ozone generated by the ozone generating unit (200) to discharge bubbles comprising ozone and hydroxyl radicals; an ultrasonic generating unit (400), connected to the filter cartridge (300) to generate ultrasonic waves; an air supply fan (500), configured to supply air to the air flow path of the housing (100); and a power supply unit, configured to supply power for driving the ozone generating unit (200), the ultrasonic generating unit (400), and the air supply fan (500).
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: November 7, 2023
    Inventors: Guodong Du, Monagas Asensio Pedro
  • Methods, compositions and systems for microfluidic assays
    Patent number: 11808767
    Abstract: Provided herein, among other aspects, are methods and apparatuses for analyzing particles in a sample. In some aspects, the particles can be analytes, cells, nucleic acids, or proteins and contacted with a tag, partitioned into aliquots, detected by a ranking device, and isolated. The methods and apparatuses provided herein may include a microfluidic chip. In some aspects, the methods and apparatuses may be used to quantify rare particles in a sample, such as cancer cells and other rare cells for disease diagnosis, prognosis, or treatment.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: November 7, 2023
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Mengxia Zhao, Wyatt Nelson, Perry G. Schiro
  • Covalently modified surfaces, kits, and methods of preparation and use
    Patent number: 11801508
    Abstract: In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: October 31, 2023
    Assignee: Berkeley Lights, Inc.
    Inventors: Randall D. Lowe, Jr., Alexander J. Mastroianni, Mark P. White, Gregory G. Lavieu, Kristin G. Beaumont
  • Control of N-(phosphonomethyl)iminodiacetic acid conversion manufacture of glyphosate
    Patent number: 11802835
    Abstract: This invention relates to the preparation of N-(phosphonomethyl)glycine (“glyphosate”) from N-(phosphonomethyl)iminodiacetic acid (“PMIDA”), and more particularly to methods for control of the conversion of PMIDA, for the identification of reaction end points relating to PMIDA conversion and the preparation of glyphosate products having controlled PMIDA content.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: October 31, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Donald D. Soleta, Peter E. Rogers, Eduardo A. Casanova, Robert E. Byrd, Eric A. Haupfear
  • Rapid high amylose wheat seed purity test
    Patent number: 11802838
    Abstract: Described herein are methods for quickly measuring properties of grain kernels. The methods allow for a quick, qualitative assessment of high amylose content in the grain kernel. The methods described herein allow for the assessment of high amylose content in wheat in either a laboratory setting or in the field with a minimum of equipment required. The results of these methods may be used to determine if high amylose kernels have been contaminated with normal or low amylose kernels.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: October 31, 2023
    Assignee: BAY STATE MILLING COMPANY
    Inventors: Tanya Jeradechachai, Sean Finnie, Alexis Schuko
  • Support for test device
    Patent number: 11801513
    Abstract: A support holder for a test device is disclosed, wherein the holder may include a base having a first plurality of sidewalls having a first length and a second plurality of sidewalls having a second length, wherein the second length is greater than the first length, wherein the plurality of sidewalls define a cavity in the base, the cavity including a surface for receiving a portion of the test device; and a plurality of projections extending away from the base, wherein each projection of the plurality of projections is configured to be associated with a leg portion, and wherein a first sidewall of the first plurality of sidewalls includes a center notch positioned between a first corner portion and a second corner portion, and wherein a second sidewall of the first plurality of sidewalls includes a removable portion configured to cover an opening into an interior of the base.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: October 31, 2023
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Christopher Hunter, Steven Davis, Melissa Sher, David Vanhoute
  • Method for manufacturing near-infrared sensor cover
    Patent number: 11802332
    Abstract: A method for manufacturing a near-infrared sensor cover includes arranging a mask in a region of an undercoating layer formed on a rear surface of a base, the region being different from a heater formation region in which a heater is to be formed and different from a belt-shaped separation region extending along an edge of the heater formation region, forming a heat-generating film on the mask and the undercoating layer, the heat-generating film being made of the conductive heat-generating material, peeling, using a laser, the heat-generating film formed in the separation region, and removing the mask and the heat-generating film formed on the mask. The separation region has a width that is set to be smaller than a beam diameter of each of near-infrared rays transmitted from the transmitting portion.
    Type: Grant
    Filed: February 17, 2022
    Date of Patent: October 31, 2023
    Assignee: TOYODA GOSEI CO., LTD.
    Inventors: Risa Hirano, Koji Okumura, Koji Fukagawa, Katsuyuki Hirano
  • Device and method of gas hydrate pressure maintaining replacement for in-situ Raman analysis
    Patent number: 11796526
    Abstract: The invention discloses a gas hydrate pressure maintaining replacement device and method for in-situ Raman analysis. Comprehensive experiments such as the formation/decomposition/displacement of high-pressure gas hydrates can be realized, and in-situ Raman characterization can be performed. Including reaction kettle system with temperature control unit, pressure control gas supply system, pressure holding system, replacement gas system, sample pre-cooling system, vacuum system and data acquisition and processing system. The device can solve the problem that the Raman peak position of the 512 cage is covered by the Raman peak position of the gas when the high-pressure gas hydrate is characterized in situ in the reaction kettle, at the same time, it solves the problems of sampling difficulties in ex-situ Raman characterization and experimental errors caused by sample transfer.
    Type: Grant
    Filed: August 31, 2019
    Date of Patent: October 24, 2023
    Assignee: DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Yongchen Song, Jiafei Zhao, Man Li, Lei Yang, Weiguo Liu, Mingjun Yang, Yanghui Li, Zheng Ling, Yu Liu, Yi Zhang, Dayong Wang
  • Microfluidic devices including fluidic multiplexers
    Patent number: 11794186
    Abstract: An example microfluidic device comprises a plurality of fluidic channels and a fluidic multiplexor. The fluidic multiplexor includes a plurality of fluidic micro-valves fluidically coupled to the plurality of fluidic channels, and a plurality of control lines that cross the plurality of fluidic channels proximal to the plurality of fluidic micro-valves.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: October 24, 2023
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Pavel Kornilovich, Alexander Govyadinov, Anand Samuel Jebakumar
  • Room temperature oxygen sensors
    Patent number: 11796457
    Abstract: Highly accurate oxygen sensors made of graphene and titanium dioxide hybrid material are provided. With UV illumination, the disclosed sensors are capable of detecting O2 gas at room temperature and ambient pressure. The sensors are able to detect oxygen at concentrations ranging from about 0.2% to about 10% by volume under 365 nm UV light, and at concentrations ranging from 0.4% to 20% by volume under short wave UV light. The disclosed sensors have fast response and recovery times and can also be used to detect ozone.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: October 24, 2023
    Inventors: Jing Li, Kevin Kailin Du
  • Real-time management of analyte recovery
    Patent number: 11796549
    Abstract: An embodiment provides a method for real-time management of analyte recovery within a system for measuring at least one parameter of a fluid within the system by monitoring signals from the system against a set of conditions, the method including: receiving, from the system, signals providing information regarding the system, wherein the system includes at least one reagent flowing into the system and recovers analytes within the fluid, wherein the analytes provide an indication of a value of the at least one parameter; identifying, by analyzing the signals, whether the analyte recovery of the system is meeting the set of conditions identifying a desired analyte recovery of the system; and modifying, based upon the analyte recovery not meeting the set of conditions, conditions of the system for recovery of the analyte, wherein the modifying includes adjusting at least one parameter of the system.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: October 24, 2023
    Assignee: Hach Company
    Inventors: Vishnu Vardhanan Rajasekharan, Cary Burton Jackson, Russell Young