Patents Examined by Joel F Brutus
  • Patent number: 11445989
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating visualization data for a selected neuro-network. In one aspect, a method comprises: receiving selection data selecting a network in a brain of a subject; processing magnetic resonance image data of the brain to identify a set of tracts that are predicted to be included in the selected network; processing the set of tracts to identify a proper subset of the set of tracts as being spurious tracts; generating a set of valid tracts by filtering the spurious tracts from the set of tracts that are predicted to be included in the selected network; providing visualization data for the selected network showing a three-dimensional spatial representation of both: (i) the valid tracts, and (ii) the spurious tracts, wherein the spurious tracts are visually distinguished from the valid tracts.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: September 20, 2022
    Assignee: Omniscient Neurotechnology Pty Limited
    Inventors: Michael Edward Sughrue, Stephane Philippe Doyen, Kieran Mann
  • Patent number: 11446091
    Abstract: A method and system are provided for determining a navigation pathway for an invasive medical instrument in a blood vessel is provided. The method includes receiving a first medical image. The method further includes determining one or more parameters associated with the first medical image. Additionally, the method includes identifying a second medical image in a computer memory, based on the determined one or more parameters. Furthermore, the method includes modifying the second medical image based on the first medical image. The method also includes determining from the modified second medical image the navigation pathway for the invasive medical instrument.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: September 20, 2022
    Assignee: Siemens Healthcare GmbH
    Inventor: Sham S Lonkadi
  • Patent number: 11445997
    Abstract: Systems and methods for accurately measuring changes in biomarker sensitive hydrogel volume and shape due to exposure to various biomarkers include a system for identifying one or more dimensional changes in a biomarker sensitive hydrogel positioned within an in vivo environment. The system includes a biomarker sensitive hydrogel positioned within an in vivo environment and configured to dimensionally change in response to interaction with predefined biomarkers. The system additionally includes an ultrasound transducer for locating and identifying one or more characteristics of the biomarker sensitive hydrogel and a computer system in electrical communication with the ultrasound transducer. The computer system is configured to receive characteristics of the biomarker sensitive hydrogel from the ultrasound transducer and determine dimensional changes of the biomarker sensitive hydrogel based on the received characteristics.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: September 20, 2022
    Assignees: UNIVERSITY OF UTAH RESEARCH FOUNDATION, SENTIOMED, INC.
    Inventors: Mahender nath Avula, Douglas A. Christensen, Navid Farhoudi, Stan Kanarowski, Julia Koerner, Jules John Magda, Rami Sami Marrouche, Christopher F. Reiche, Florian Solzbacher, Michael David Sorenson
  • Patent number: 11439312
    Abstract: A plurality of modules are simultaneously positioned at locations that correspond to different angiosomes. Each of these modules has a front surface shaped and dimensioned for contacting a person's skin, a plurality of different-wavelength light sources aimed in a forward direction, and a plurality of light detectors aimed to detect light arriving from in front of the front surface. Each module is supported by a support structure (e.g., a strap or a clip) that is shaped and dimensioned to hold the front surface adjacent to the person's skin at a respective position. Perfusion in each of the angiosomes is monitored using these modules, and the surgeon can rely on this information to guide his or her intervention.
    Type: Grant
    Filed: April 23, 2017
    Date of Patent: September 13, 2022
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Andreas H. Hielscher, Christopher J. Fong, Jennifer Hoi, Hyun K. Kim, Michael Khalil
  • Patent number: 11432735
    Abstract: The present disclosure relates to a method for controlling a magnetic resonance imaging guided radiation therapy apparatus (100) comprising a magnetic resonance imaging system (106). The method comprises: acquiring magnetic resonance data using the magnetic resonance imaging system from an organ (146), the organ being marked by a predefined marker; the magnetic resonance data comprising 3D image data; identifying in a reconstructed 2D image of the magnetic resonance data at least one signal void candidate of the marker; processing the 3D image data and the identified signal void for calculating a likelihood that the identified signal void candidate is part of the marker; outputting an indication of the calculated likelihood; in response to the outputting, receiving a user input specifying performing a radio therapy; and controlling the irradiation of the organ using the radiation therapy.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: September 6, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Teuvo Juhani Vaara, Erkki Tapani Vahala
  • Patent number: 11432801
    Abstract: A method and system are provided for guiding a needle to a target location within a subject. The system comprises a probe and a needle guide. The probe includes two or more transducers that are arranged to direct sound waves toward a target location on a subject. The needle guide can be detachably coupled to the probe, and may be used to maintain the needle within viewing planes of the transducers while the needle is inserted into the subject. To facilitate guidance of the needle, a real-time image of the target region can be produced by overlaying images produced by the two or more transducers. Such a system may provide a more adaptive and reliable way to guide the insertion of a needle, allowing for more sophisticated and fool-proof viewing planes, improved versatility, and more ergonomic needle control.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: September 6, 2022
    Assignee: DUKE UNIVERSITY
    Inventor: Charles Y. Kim
  • Patent number: 11432805
    Abstract: Vector Doppler Imaging (VDI) improves on conventional Color Doppler Imaging (CDI) by giving speed and direction of blood flow at each pixel of a display generated by a computing system. Multiple angles of Plane wave transmissions (PWT) via an ultrasound transducer conveniently give projected Doppler measurements over a wide field of view, providing enough angular diversity to identify velocity vectors in a short time window while capturing transitory flow dynamics. A fast, aliasing-resistant velocity vector estimator for PWT is presented, and VDI imaging of a carotid artery with a 5 MHz linear array is shown using a novel synthetic particle flow visualization method.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: September 6, 2022
    Assignee: Verasonics, Inc.
    Inventors: John Flynn, Ronald Elvin Daigle
  • Patent number: 11436737
    Abstract: A cluster-based approach and template-based approach are combined to segment brain matter from a three-dimensional MRI image of voxels. The morphological information captured by the template-based approach may be used to refine the segmentation produced by the cluster-based approach. Conversely, the “similarity” information captured by the cluster-based approach may be used to refine the segmentation produced by the template-based approach.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: September 6, 2022
    Assignee: Ricoh Company, Ltd.
    Inventors: Krishna Prasad Agara Venkatesha Rao, Srinidhi Srinivasa
  • Patent number: 11426611
    Abstract: The present disclosure is directed to a precision ultrasound scanner for imaging, for example, the prostate in a way that produces a superior image of the prostate while removing the iatrogenic risk and patient discomfort associated with other methods of providing an ultrasound image of the prostate. The present disclosure describes an apparatus and method for forming a high precision image of the prostate from outside the patient's body wherein the resolution in sufficient to image, for example, cancerous lesions on the surface of the prostate. To achieve such images, coded excitation, tissue harmonic imaging, advanced transducers operating in the 10 MHz to 40 MHz range is used to achieve a useable signal-to-noise reflection while being able to position the imaging transducer as close as possible to the prostate without risk or discomfort to the patient.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: August 30, 2022
    Assignee: ArcScan, Inc.
    Inventors: John D. Watson, Andrew K. Levien
  • Patent number: 11419516
    Abstract: A table for an MRI system includes a top surface for supporting a patient being imaged and a motion sensor for sensing motion of the patient. The motion sensor is located below the top surface and includes a self-resonant spiral (SRS) coil and a coupling loop. The coupling loop generates a drive RF signal to excite the SRS coil to radiate a magnetic field having a predefined resonant frequency. The coupling loop also receives a reflection RF signal from the SRS coil. The motion sensor is located such that at least a portion of a torso of the patient being imaged is within the magnetic field. A controller is configured to detect patient motion based on the reflection RF signal.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: August 23, 2022
    Assignee: GE Precision Healthcare LLC
    Inventors: Randall H. Buchwald, Louis Jay Vannatta
  • Patent number: 11423532
    Abstract: According to embodiment, an image processing apparatus comprising a specifying unit and a display controller. The specifying unit that specifies an acquisition position of an indicator relating to blood flow on a blood vessel-containing image collected by a medical image diagnostic apparatus. The display controller that displays the acquisition position on the blood vessel-containing image and displays the indicator on a display unit in association with the acquisition position.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: August 23, 2022
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Akihito Takahashi, Satoshi Wakai, Takuya Sakaguchi
  • Patent number: 11420018
    Abstract: In the present invention, an interface control module for controlling a mapping/imaging/recording system is provided for placement on a catheter control handle. The interface control module includes control elements that are operably connected to the mapping/imaging/recording system in order to control various functions of the imaging/recording system relating to images represented on a display forming a part of the mapping/imaging/recording system. The interface control module can be integrated with the catheter control handle or can be formed as a separate component that is releasably attachable to the catheter control handle to enable a use to operate the mapping/imaging/recording system from the catheter control handle being utilized in an interventional medical procedure.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: August 23, 2022
    Assignee: General Electric Company
    Inventors: Rodger F. Schmit, Adrian F. Warner, Daniel R. Schneidewend, Timothy P. Stiemke
  • Patent number: 11412976
    Abstract: A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: August 16, 2022
    Assignee: The General Hospital Corporation
    Inventors: Quan Zhang, Gary Strangman
  • Patent number: 11406454
    Abstract: A surgical needle comprising: (a) a sensor; (b) a distal tip with the sensor being located at the distal tip; (c) a needle advancing mechanism that is adjustable to change an insertion depth; and (d) a control unit in communication with the needle advancing mechanism; wherein the sensor provides a signal to the control unit regarding a thickness of a feature of interest and the control unit controls the insertion depth based upon the signal from the sensor so that the insertion depth into the feature of interest is varied or the control unit prevents the needle advancing mechanism from activating.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: August 9, 2022
    Assignee: Gyrus ACMI, Inc.
    Inventors: Kester J. Batchelor, Nikhil M. Murdeshwar
  • Patent number: 11406455
    Abstract: A microscopy system includes a microscope, a stand configured to mount the microscope and including a drive device configured to move the microscope, a detection device configured to detect a spatial position of a target fastened to a body part or to an instrument, wherein the position detection device includes the target with at least one marker element and an image capture device configured to optically capture the target. The microscopy system further includes at least one control device configured to operate the microscopy system according to the detected position of the target, wherein the position detection device is configured to determine the position of the target by evaluating a two-dimensional image of the image capture device. In addition, a method for operating the microscopy system is provided.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: August 9, 2022
    Assignee: Carl Zeiss Meditec AG
    Inventors: Stefan Saur, Christian Voigt, Marco Wilzbach, Christoph Hauger
  • Patent number: 11406338
    Abstract: Apparatus and methods are described including acquiring 3D image data of a targeted vertebra. A processor indicates the targeted vertebra within the 3D image data. A radiopaque element is positioned on the body of the subject with respect to the spine and a radiographic image is acquired. The processor (a) generates a plurality of 2D projections of the targeted vertebra from the 3D image data, (b) for each vertebra that is visible in the radiographic image, identifies if there exists a 2D projection of the targeted vertebra that matches the radiographic image of the vertebra that is visible, and (c) in response, indicates on the 2D radiographic image the vertebra for which a match with a projection of the targeted vertebra was identified, such that a location of the targeted vertebra is identified with respect to the radiopaque element. Other applications are also described.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: August 9, 2022
    Assignee: Vuze Medical Ltd.
    Inventor: David Tolkowsky
  • Patent number: 11399757
    Abstract: fMRI data of a subject brain is accessed and may include a plurality of time-sequenced volumetric images of activity in a subject brain. A plurality of emotion vectors are accessed, each emotion vector tagged with a specified emotional state. From the fMRI data and using the emotion vectors, a plurality of fMRI state vectors are determined at various points in time, where each fMRI state vector is a combination of the emotion vectors and represents the state of the subject brain at a particular point in time. Flow data is determined to identify a trajectory, over time, of the subject brain as reflected by the fMRI data, through a state space defined by the emotion vectors, where the flow data is based at least in part on the fMRI vectors at various points in time. From the flow data, data is generated that shows changes, through time, in at least one emotional state of the brain.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: August 2, 2022
    Assignee: Omniscient Neurotechnology Pty Limited
    Inventors: Michael Edward Sughrue, Stephane Philippe Doyen, Peter James Nicholas
  • Patent number: 11403778
    Abstract: An ultrasound image processing apparatus (16) is disclosed comprising a processor arrangement (46, 50) adapted to receive a temporal sequence (15) of ultrasound images (150) of at least a chest region (151) of a fetal entity (62) from an ultrasound probe (14), said chest region including the fetal heart (171), said temporal sequence capturing at least part of a cardiac cycle of the fetal heart; identify the chest region of the fetal entity in one or more of the ultrasound images of said temporal sequence; identify a portion of the spine in the identified chest region; calculate an orientation axis (160) of the fetal chest from the identified chest region and the identified spine portion; identify the septum of the fetal heart as a linear structure which is temporally more stable than its surrounding structures in said temporal sequence of ultrasound images and which defines a region of convergence of the movements of the fetal heart during said cardiac cycle; calculate an orientation axis (170) of the fetal h
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: August 2, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Cybèle Ciofolo-Veit, Laurence Rouet, Caroline Denise Francoise Raynaud, David Nigel Roundhill
  • Patent number: 11395708
    Abstract: Robotic systems and methods for the automatic guidance of medical catheters into anatomical structures during various medical procedures are disclosed. A motor controlled insertion mechanism and a motor controlled rotation mechanism are configured to combine catheter insertion and rotation such as to twist the catheter while advancing into the anatomical structure. A navigation-system determines the position in the anatomical structure of a tracking-sensor disposed on the tip of the catheter. The motion of the catheter is controlled via the motors A controller controls, via the motors, the movement of the catheter into the anatomical structure function of the position of the tracking sensor. The methods, systems and devices described herein significantly decrease X-ray exposure to both patient and doctor, minimize friction between the catheter and robotic components, reduce the size of robotic systems, reduce production costs, and reduce the duration of clinical procedures.
    Type: Grant
    Filed: June 15, 2019
    Date of Patent: July 26, 2022
    Inventor: Gabriel Gruionu
  • Patent number: 11382698
    Abstract: A surgical navigation system according to one embodiment may comprise: an electromagnetic wave generation unit; a first detection unit attached to a surgical site of an object to detect a position attached to the surgical site; a second detection unit installed in a patient-specific surgical guide instrument inserted into the surgical site to receive the electromagnetic wave and detect the position of the patient-specific surgical guide instrument; a third detection unit installed in the surgical instrument inserted into the surgical site to detect the position of the surgical instrument; an information processing unit for registering the position of the first detection unit and the position of the third detection unit and for tracking the position of the surgical instrument on the basis of the position of the first detection unit attached to the surgical site, by setting the position of the patient-specific surgical guide instrument as a reference position when the patient-specific surgical guide instrument
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: July 12, 2022
    Assignees: Kyungpook National University Industry-Academic Cooperation Foundation, Korea Advanced Institute of Science and Technology
    Inventors: Jun Young Kim, Min Kyu Je, Anna Seo, Shin Yoon Kim, Hyun Deok Kim, Hyun Mun Kim