Abstract: Systems and methods for measuring changes in smart hydrogel microresonator structures positioned in an in vivo or other environment, having an acoustic resonance frequency in an ultrasound range. The system includes a smart hydrogel microresonator structure positioned within the environment configured to exhibit a change in resonance frequency in response to interaction with one or more predefined analytes in the environment. The system includes an ultrasound transducer for querying the smart hydrogel microresonator structure at or near its resonance frequency. The system also includes a computer system configured to receive ultrasound data as provided by query of the smart hydrogel microresonator structure and to determine changes in resonance frequency, amplitude or intensity of the ultrasound query wave, or mean grayscale value (MGV) associated with the ultrasound data of the smart hydrogel microresonator structure due to the change in resonance frequency.

Abstract: The invention provides for a magnetic resonance imaging system (100, 300). The magnetic resonance imaging system comprises: a subject support (120) configured for moving a subject between a loading position (121) and an imaging position (200); a receive magnetic resonance imaging coil (114) configured for being placed on the subject; and a light detection system (115) comprising at least one ambient light sensor for measuring light data (144). The light detection system is any one of the following: mounted to the main magnet such that the light data is measured from the imaging zone and mounted to the receive magnetic resonance imaging coil.

Abstract: A registration marker (40), consisting of a radiotransparent substrate (44) and a pattern (58) formed in at least two dimensions, which is disposed on the substrate and is optically visible. The registration marker also has a multiplicity of radiopaque elements (60), which are disposed in the substrate and are spatially arranged in at least two dimensions to provide a unique pattern.

Abstract: A registration marker (40), consisting of a radiotransparent substrate (44) and a pattern (58) formed in at least two dimensions, which is disposed on the substrate and is optically visible. The registration marker also has a multiplicity of radiopaque elements (60), which are disposed in the substrate and are spatially arranged in at least two dimensions to provide a unique pattern.

Abstract: A registration marker comprising a radiotransparent substrate and a pattern formed in at least two dimensions, which is disposed on the substrate and is optically visible. The registration marker also has a multiplicity of radiopaque elements, which are disposed in the substrate and are spatially arranged in at least two dimensions to provide a unique pattern.

Abstract: Systems and methods of predicting future medical events are based on the processing of medical image. The prediction of premature birth and estimation of gestational age based on ultrasound images are presented as illustrative examples. The new abilities to estimate the probability of future medical events, before they otherwise could be predicted, provides new avenues for the development of preventative treatments.

Abstract: Machine learning is used to train a network to estimate a three-dimensional (3D) body surface and body regions of a patient from surface images of the patient. The estimated 3D body surface of the patient is used to determine an isocenter of the patient. The estimated body regions are used to generate heatmaps representing visible body region boundaries and unseen body region boundaries of the patient. The estimation of 3D body surfaces, the determined patient isocenter, and the estimated body region boundaries may assist in planning a medical scan, including automatic patient positioning.

Abstract: A surgical system includes at least one light emitter generating light at a first intensity and an array of light sensors including a least one row of light sensors, individual light sensors in the row of light sensors adapted to generate a signal including a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer to determine the magnitudes of the non-pulsatile components at the individual light sensors in the row of light sensors, to determine if the non-pulsatile component transitions from a higher magnitude to a lower magnitude and from a lower magnitude to a higher magnitude, and if so, to determine if the first intensity should be changed to a second intensity.

Abstract: Systems and methods for non-invasive blood pressure measurement are disclosed. In some embodiments, a system comprises a wearable member configured to generate first and second signals, and a blood pressure calculation system. The blood pressure calculation system a pre-processing module configured to filter noise from the signals, and a wave selection module configured to identify subsets of waves of the signals, a feature extraction module configured to generate sets of feature vectors form the subsets of waves, and a blood pressure processing module configured to calculate an arterial blood pressure value based on the sets of feature vectors and an empirical blood pressure calculation model, the empirical blood pressure calculation model configured to receive the sets of feature vectors as input values. The blood pressure calculation system further includes a communication module configured to provide a message including or being based on the arterial blood pressure value.

Abstract: A method for determining a predicted risk level of a clinical endpoint for a predetermined time period for a patient is provided by the present disclosure. The method includes receiving video frames of a heart, the video frames being associated with the patient, receiving electronic health record data including a number of variables associated with the patient, providing the video frames and the electronic health record data to the trained neural network, receiving a risk score from the trained neural network, and outputting a report based on the risk score to at least one of a display or a memory.

Abstract: Disclosed are systems and methods for assisting with procedures involving a subject's joint, such as a joint. Robotic devices move and position the subject to manipulate the joint and sensing devices sense the joint gap. The robotic devices are controlled based on the joint gap. Novel techniques are disclosed for joint gap segmentation, approximating an uncertainty in determination of the varying dimension of the joint gap, and real-time motion analysis of the joint gap size. In some examples, a kinematic model of the patient's anatomy is utilized to provide robotically assisted manipulation of the same using the techniques described herein.

Abstract: A registration fixture is configured for use with a medical imaging system. The registration fixture comprises a rigid internal structure comprising a plurality of fiducial markers arranged in a predefined pattern. The registration fixture further comprises a housing configured to surround the rigid internal structure. The registration fixture is configured to be mounted on a patient table.

Abstract: A computer vision pipeline is provided for fully automated interpretation of cardiac function, using a combination of machine learning strategies to enable building a scalable analysis pipeline for echocardiogram interpretation. Videos from patients with heart failure can be analyzed and processed as follows: 1) preprocessing of echo studies; 2) convolutional neural networks (CNN) processing for view identification; 3) segmentation of chambers and delineation of cardiac boundaries using CNNs; 4); particle tracking to compute longitudinal strain; and 5) targeted disease detection.

Abstract: A hand-control device for controlling the operation of an injection system is described herein. The hand-control device includes one or more input components that receive input to control various operations of the injection system, including commanding the injection to perform a particular operation, changing an operational aspect of the injection system, and selecting an operational mode for the injection system. A communication unit of the hand-control device generates and conveys a signal for the injection system, and receives a command signal from the injection system. An output component outputs an indication, such as a light emission, a sound, or haptic feedback, in response to receiving the command signal. In some instances, this indication acts as a confirmation or failure of the intended input.

Abstract: A system for planning and performing a repeat interventional procedure is provided which includes a registration device and an image generation device which map current targets in a reference image for a first interventional procedure to at least one guidance image acquired from a different imaging modality. Biopsy locations are recorded to the guidance images during the first interventional procedure and the biopsy locations are mapped to the reference image to provide a planning image for use in a subsequent interventional procedure on the patient. In a subsequent interventional procedure, the prior planning image (124) may be registered to a current reference image and the prior biopsy locations and prior and current targets are mapped to a guidance image acquired from a different imaging modality. Biopsy locations are then mapped to the guidance image and mapped back to the current reference image.

Abstract: A medical device position guidance system includes a plurality of noninvasive external detector devices communicable with an invasive medical device. A magnetic field is used to gather information about the anatomical size and shape of a subject, such as a human. The medical device position guidance system further uses the magnetic field to obtain information about the positioning of the invasive medical device relative to the subject's anatomy. A method of using the medical device position guidance system is also provided.

Abstract: A method for monitoring thoracic tissue. The method comprises intercepting reflections of electromagnetic (EM) radiation reflected from thoracic tissue of a patient in radiation sessions during a period of at least 24 hours, detecting a change of a dielectric coefficient of the thoracic tissue by analyzing respective the reflections, and outputting a notification indicating the change. The reflections are changed as an outcome of thoracic movements which occur during the period.

Abstract: A method of applying a topical numbing agent to a nasal cavity without sedating a patient may include inserting a catheter into a nostril of the patient, the catheter having a first bend that forms a first angle such that at least a portion of the catheter is non-linear. The method may also include guiding a distal end of the catheter into the nasal cavity using a computerized tomography (CT) system by aligning a distal end of the catheter with a first cavity portion of the nasal cavity using a projection of the catheter within the nasal cavity on a CT scan of the patient, and moving the catheter within the nasal cavity while dynamically displaying the projection of the catheter by the CT system relative to the nasal cavity. The method may further include dispensing the topical numbing agent through the catheter into the first cavity portion.

Abstract: One or more devices, systems, methods, and storage mediums for optical imaging medical devices, such as, but not limited to, Optical Coherence Tomography (OCT), single mode OCT, and/or multi-modal OCT apparatuses and systems, and methods and storage mediums for use with same, for triggering auto-pullback, including for devices or systems using blood clearing, are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Techniques provided herein also improve processing and imaging efficiency while achieving images that are more precise.

Abstract: An implantable tissue marker device is provided to be placed in a soft tissue site through a surgical incision. The device can include a bioabsorbable body in the form of a spiral and defining a spheroid shape for the device, the spiral having a longitudinal axis, and turns of the spiral being spaced apart from each other in a direction along the longitudinal axis. A plurality of markers can be disposed on the body, the markers being visualizable by a radiographic imaging device. The turns of the spiral are sufficiently spaced apart to form gaps that allow soft tissue to infiltrate between the turns and to allow flexibility in the device along the longitudinal axis in the manner of a spring.