Abstract: A method for determining a predicted risk level of a clinical endpoint for a predetermined time period for a patient is provided by the present disclosure. The method includes receiving video frames of a heart, the video frames being associated with the patient, receiving electronic health record data including a number of variables associated with the patient, providing the video frames and the electronic health record data to the trained neural network, receiving a risk score from the trained neural network, and outputting a report based on the risk score to at least one of a display or a memory.

Abstract: Methods and systems for performing robotically-assisted surgery in conjunction with intra-operative imaging. A method includes moving a robotic arm with respect to a patient and an imaging device to move an end effector of the robotic arm to a pre-determined position and orientation with respect to the patient based on imaging data of the patient obtained by the imaging device. The robotic arm maintains the end effector in the pre-determined position and orientation with respect to the patient and does not collide with the imaging device or with the patient when the imaging device moves with respect to the patient.

Abstract: Pre-surgical planning can use a three-dimensional model of an anatomical structure having a plurality of fiduciary points and a surgical mark integrated into the three-dimensional model using a contrast material. A model image of the three-dimensional model can be superimposed with a diagnostic image of the anatomical structure using the plurality of fiduciary points in order to create a superimposed image.

Abstract: A magnetic resonance tomography unit and a method is provided in which a patient couch may be moved in relation to the longitudinal direction into the patient tunnel in the transversal direction into a left-hand side extreme position and an opposite-lying right-hand side extreme position. Using an image acquisition facility in the left-hand side extreme position a right-hand side part is acquired and in the right-hand side extreme position a left-hand side part of the outer contour of the predetermined object is acquired. Using the image acquisition facility, the outer contour of the object is subsequently created from the left-hand side part of the outer contour and also from the right-hand side part of the outer contour.

Abstract: Devices and methods for ultrasound image-guided percutaneous, cardiac valve implantation and repair comprise, in combination, a plurality of devices including but not limited to an ultrasound-image guided catheter, a pericardial sheath, a cardiac-valve delivery system and an ascending aortic filter. An image-guided catheter is utilized to introduce via an introducer needle and a guide wire a pericardium portal for permitting entry from the chest wall to inside the pericardial space between the pericardial outer lining and inner lining. The pericardium portal permits the use of ultrasound vision to locate a site proximate the left ventricular apex, for introduction of a sheath via a .myocardium needle into the left ventricular space at an angle and avoiding any coronaries or vessels. A first delivery system permits placement of at least one aortic filter which collects any emboli, particulate matter, plaque and prevents such matter travelling via the ascending aorta to the brain, causing a stroke.

Abstract: A smart system and methods for coupling a medical transporter apparatus with an imaging apparatus, involving: a smart docking module comprising at least one coupler responsive to a controller operable by a set of executable instructions, the smart docking module comprising a non-magnetic material; and the smart docking module configured by the controller to automatically perform at least one of: position, dock, engage, latch, lock, interlock, release, emergency-release, quick-release, disengage, emergency-disengage, and quick-disengage the medical transporter apparatus in relation to the imaging apparatus.

Abstract: In a method and system for automatically positioning a region of interest of a patient for a medical imaging examination in an isocenter of a medical imaging apparatus, the region of interest of the patient is brought into a patient receiving region of the medical imaging examination for a position-determination measurement, a position-determination measurement is performed to capture position-determination image data, the position-determination image data is analyzed to determine a position of the region of interest of the patient from the position-determination image data, and the patient is automatically positioned such that the position of the region of interest of the patient coincides with the position of the isocenter of the medical imaging apparatus.

Abstract: The invention relates to a method for determining ischemic status. The method comprises acquiring magnetic resonance diffusion tensor matrices and obtaining a relative decrease of diffusion magnitude due to the ischemic status from the magnetic resonance diffusion tensor matrices. The invention also relates to a method for assessing stroke onset time. The method comprises acquiring magnetic resonance diffusion tensor matrices and obtaining a relative decrease of pure anisotropy due to stroke from the magnetic resonance diffusion tensor matrices.

Abstract: An analyzing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to detect a shear wave propagating in an object. The processing circuitry is configured to calculate an index value that indicates viscosity within the object and that is not dependent on any physical model related to viscoelasticity, by analyzing the detected shear wave.

Abstract: A system and method of implanting pacing lead in a patient's heart. The system may include a catheter configured to by inserted through the coronary sinus ostium such that the distal end region of the catheter is positioned past the anterolateral vein and proximate at least one septal perforating vein. The catheter is configured to inject contrast proximate the septal perforating vein to identify an implant region for a pacing lead. Further, a controller is configured to deliver pacing therapy to the implant region.

Abstract: A brachytherapy applicator is formed to use when administering therapeutic radiation to a particular patient's targeted area via brachytherapy. This process accesses image information for a patient that includes the targeted area and at least some adjacent non-targeted area. A control circuit uses that image information with prescribed dosing information for that patient to automatically generate a brachytherapy applicator design specifically to treat the particular patient's targeted area via brachytherapy. A corresponding brachytherapy applicator is then manufactured as a function, at least in part, of the brachytherapy applicator design to provide a manufactured brachytherapy applicator.

Abstract: A system for determining a location for a surgical procedure, having a 3D spatial mapping camera, the 3D spatial mapping camera configured to map a bone. The system also includes a marker attached to a distal end section of the bone, such that the 3D spatial mapping camera is configured to capture a plurality of images of the marker as the bone is rotated in a non-linear path. The images also include data identifying a location of the marker. The system also includes a computer system that receives the data from the images captured by the 3D spatial mapping camera and determines a location of a mechanical axis of the bone, and a mixed reality display, where the computer system is configured to send the location of the mechanical axis to the mixed reality display and the mixed reality display is configured to provide a virtual display of the mechanical axis of the bone.

Abstract: A microscopy system includes a microscope, a stand configured to mount the microscope and including a drive device configured to move the microscope, a detection device configured to detect a spatial position of a target fastened to a body part or to an instrument, wherein the position detection device includes the target with at least one marker element and an image capture device configured to optically capture the target. The microscopy system further includes at least one control device configured to operate the microscopy system according to the detected position of the target, wherein the position detection device is configured to determine the position of the target by evaluating a two-dimensional image of the image capture device. In addition, a method for operating the microscopy system is provided.

Abstract: Respective longitudinal insertion paths for two tools are planned and associated with 3D image data of a skeletal portion. While respective portions of the tools are disposed at first respective locations along their respective longitudinal insertion paths, first and second x-rays of the respective portions of the tools and the skeletal portion are acquired from respective first and second views. A computer processor matches between a tool in the first x-ray and the same tool in the second x-ray by: (A) identifying respective tool elements of each tool within the first and second x-rays, (B) registering the first and second x-rays to the 3D image data, and (C) based upon the identified respective tool elements and the registration, identifying for at least one tool element a correspondence between the tool element and the respective planned longitudinal insertion path for that tool. Other applications are also described.

Abstract: A system (11) includes a medical probe (36) for insertion into a cavity of an organ, which includes a position and direction sensor (60) and a camera (45), both operating in a sensor coordinate system (62). The system further includes a processor (44) configured to: receive, from an imaging system (21) operating in an image coordinate system (28), a three-dimensional image of the cavity including open space and tissue; receive, from the medical probe, signals indicating positions and respective directions of the medical probe inside the cavity; receive, from the camera, respective visualized locations inside the cavity; register the image coordinate system with the sensor coordinate system so as to identify one or more voxels in the image at the visualized locations, and when the identified voxels have density values in the received image that do not correspond to the open space, to update the density values of the identified voxels to correspond to the open space.

Abstract: The invention relates to an augmented reality surgical microscope (1) having a camera (2), preferably a multispectral or hyperspectral camera. The augmented reality surgical microscope (1) retrieves input image data (22) of an object (8) comprising in particular live tissue (10). The input image data (22) comprise visible-light image data (26) as well as fluorescent-light image data (24) of at least one fluorophore (14). The augmented reality surgical microscope (1) permits the automatic identification and marking in pseudo-color (86) of various types of vascular plexus structures (54a 54b, 54c) and/or of blood flow direction (56) depending on the fluorescent-light image data (24). A pre-operative three-dimensional atlas (36) and/or ultrasound image data (39) may be elastically matched to the visible-light image data (26). The augmented reality surgical microscope (1) allows different combinations of the various image data to be output simultaneously to different displays (75).

Abstract: According to one embodiment, a medical diagnostic apparatus includes processing circuitry and display circuitry. The processing circuitry estimates a position of a structure in a subject based on data obtained by scanning with respect to the subject and analyzes tissue characterization in the subject. The display circuitry displays an analysis result of the tissue characterization obtained by the processing circuitry with respect to a plurality of positions in the subject except for the estimated structure position.

Abstract: An implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ) containing at least one loop. The coiled marker is deployed to mark a tissue site in the body for subsequent surgery, and a magnetic detection system with a handheld probe excites the marker above or below the switching field required for bistable switching of the marker causing a harmonic response to be generated in a bistable or sub-bistable mode that allows the marker to be detected and localised.

Abstract: Method for optimizing an MR control sequence for acquiring MR data of an examination subject by means of an MR device having gradient coils. The method includes providing an MR control sequence having sequence portions, each having an excitation portion, a phase encoding portion and a readout portion, wherein the phase encoding portion is arranged in each case between the excitation portion and the readout portion with respect to time; providing a defined parameter for the MR control sequence; providing an optimization objective; ascertaining usage time of the gradient coils between the excitation portion and the readout portion with respect to time for each of the sequence portions; optimizing the excitation portions for each of the sequence portions considering the ascertained usage time for the corresponding sequence portion and the defined parameter with regard to the optimization objective; and providing the optimized MR control sequence having the optimized excitation portions.

Abstract: A method for analysing a structure within a patient's heart includes receiving a patient study including a plurality of images of the patient's heart obtained by an ultrasound device, extracting respective sets of pixel data from the images, and using trained machine learning algorithms to analyse the sets of pixel data to a) identify first images captured using a colour Doppler modality and assign the first images to said structure, b) identify second images captured using spectral Doppler modality and assign the second images to said structure, c) determine a flow convergence zone radius from an analysis of the first images; and d) determine a maximum gradient of structure, from an analysis of the second images. The flow convergence zone radius, the maximum gradient of structure, and a Nyquist value identified for the colour Doppler modality, are combined to determine an Effective Regurgitant Orifice Area for the structure.