Abstract: This invention pertains to an improved process for preparing noncyclic polyalkylene polyamine compounds in high selectivity by reacting an alkanolamine and an alkylene amine in the presence of an inert gas and an acidic catalyst. The improvement resides in effecting the reaction under fixed bed catalytic conditions and maintaining the reaction conditions such that a vapor phase condition exists for the reaction mixture comprising both reactants and products. To accomplish the formation of vapor phase conditions sufficient inert gas is injected into the feedstream along with alkanolamine and alkylene amine so that the dew point temperature of the reaction product mix is below the reaction temperature at reaction pressure.

Abstract: There are provided compounds of formula I, ##STR1## in which R.sub.1 represents OH,R.sub.2 and R.sub.3, which may be the same or different, each independently represent hydrogen, fluorine, chlorine, bromine, alkyl C1 to 6, nitro, nitrile, (CH.sub.2).sub.p R.sub.9 or SR.sub.9,W represents a single bond, a 1,2; 1,3; or 1,4-disubstituted benzene ring; a --CH.dbd.CH--group or a 1,4-cyclohexanediyl group;X respresents NH, O, S, SO.sub.2, CO, CH.sub.2, CONH or --COO;Y represents (CH.sub.2)q, CO, CS, SO.sub.2 and R.sub.20 represents hydrogen,or Y represents CR.sub.15 R.sub.16 CR.sub.17 R.sub.18,wherein the carbon atom bearing R.sub.15 and R.sub.16 is adjacent to X and in whichR.sub.15 and R.sub.18, together with the carbon atom to which they are attached form a carbonyl group, and R.sub.15, R.sub.16 and R.sub.20 each represent hydrogen, orR.sub.15 and R.sub.20 together form a chain --CH.sub.2 --, and R.sub.16, R.sub.17 and R.sub.18 each represent hydrogen, orR.sub.15, R.sub.16, R.sub.17 and R.sub.

Abstract: Diamines corresponding to the general formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 may be identical or different and represent hydrogen or straight- or branched-chain C.sub.1 -C.sub.12 alkyl groups, provided that two of the radicals,R.sup.1, R.sup.2 and R.sup.3, represent hydrogen, m and n each represent 0 or 1, provided that m+n=1; where m or n=0, the free valence is saturated by hydrogen, optionally in the form of isomeric mixtures, and optionally containing up to 35%, by weight, of the corresponding perhydrogenated diamines, and up to 10%, by weight, of the corresponding unhydrogenated aromatic diamines.Also, a process for preparing these diamines by catalytically-hydrogenating the corresponding aromatic diamines with 3 moles of hydrogen per mole of diamine, or catalytically-hydrogenating the corresponding dinitro compounds with 9 moles of hydrogen per mole of dinitro compound.

Abstract: The invention relates to a process for the isomerization of o-, m- or p-toluidine, or of a mixture of them, on a zirconium-containing zeolite catalyst of the pentasil type. Catalysts of this type are distinguished by particularly high activity and a long useful life. The invention particularly relates to the preparation of m-toluidine by isomerization of o- and/or p-toluidine on zirconium-containing zeolite catalysts of the pentasil type.

Abstract: Aminopeptidase inhibitory activity is exhibited by compounds having the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl, carboxyalkyl, halo-substituted alkyl, hydroxyalkyl, aminoalkyl, mercaptoalkyl, alkylthioalkyl, (cycloalkyl)alkyl, (heteroaryl)alkyl, arylalkyl, carbamoylalkyl, guanidinylalkyl or heteroaryl; andR.sub.2 and R.sub.3 are each independently hydrogen, alkyl, cycloalkyl, hydroxyalkyl, aminoalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl.

Abstract: The present invention is concerned with the preparation of lysosomotropic detergent agents and pharmaceutical composition useful in the treatment of cancer. These compounds are amine derivatives having a pK of 3.5 of the general structure ##STR1## in which R.sub.1 is C.sub.8-30 alkyl, C.sub.8-30 -alkenyl, substituted C.sub.4-30 alkyl or substituted C.sub.4-30 -alkenyl; R.sub.2 is hydrogen or C.sub.1-4 alkyl and Y is an electron withdrawing group, to control the pK, selected from trifluoroethyl, and difluoroethyl.

Abstract: This invention relates to a class of alkenylated toluenediamines having at least one alkenyl group ortho to an amine group. More particularly the toluenediamines are represented by the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are hydrogen, C.sub.1-3 aliphatic, phenyl, halogen or alkoxy radicals, or R.sub.2 and R.sub.4 or R.sub.5 are bridged via an alkylene radical --(CH.sub.2).sub.y -- wherein y=2 to 5, and x is one or two provided that in said formula at least one of R.sub.1, R.sub.2, R.sub.3, R.sub.4 or R.sub.5 is C.sub.1 or greater.The above described alkenylated toluenediamines have been found to be well suited as antioxidants and as tri- and tetra functional chain extenders in forming polyurethane/urea elastomers systems and for providing pendant unsaturation for post curing and polymerization.

Abstract: Cycloalkyl aminophenol derivatives are produced by reacting o-, m- or p-aminophenol with a cycloalkanone having 5 to 12 carbon atoms in the presence of a reducing agent and preferably with the addition of an acid.

Abstract: Stilbene derivatives of the formula (I) ##STR1## and distyryl derivatives of the formula (II), ##STR2## as defined in the specification, and an electrophotographic photoconductor comprising an electroconductive support material and a photosensitive layer overlayed thereon comprising at least one of the above derivatives, are disclosed.

Abstract: Novel fluorinated diaminoalkyne derivatives are inhibitors of ornithine decarboxylase enzyme and have the following general Formula I: ##STR1## wherein R represents C.sub.1 -C.sub.4 alkyl, or preferably, hydrogen.

Abstract: New 1,4-diamino-5-chloro-2-nitrobenzene derivatives are disclosed of the formula I ##STR1## Wherein R.sup.1 and R.sup.2 are the same or different and are each hydrogen, 2-hydroxyethyl or 2,3-dihydroxypropyl, with the proviso, that at least one of said R.sup.1 and R.sup.2 is 2,3-dihydroxypropyl, along with processes for their production, as well as hair coloring compositions containing the same and methods of coloring hair. The compounds are red- to violet-coloring direct dyes, and are readily soluble in water, with favorable toxicological characteristics.

Abstract: Polyethers of the formula: ##STR1## wherein: R is the residue of a starting active hydrogen compound with removal of the active hydrogen atom, R.sub.1 is a C.sub.1 -C.sub.10 alkyl or aryl, R.sub.2 is a C.sub.1 -C.sub.10 alkyl, R.sub.3 is H, CH.sub.3, C.sub.2 H.sub.5 or phenyl, x is 5-100, y is 1-5, and z is 2-8 are less active than those having primary or secondary alcoholic function at terminals.

Abstract: Gem-dihalo-1,8-diamino-4-aza-octane derivatives useful as antiproliferative or antitumor agents.

Abstract: The invention provides compounds of formula: ##STR1## in which R=H, halogen, alkyl, alkyloxy, alkythio, NH.sub.2, alkylamino, dialkylamino or CF.sub.3, R.sub.3 =H or alkyl, either R.sub.4 and R.sub.5 =H and R.sub.1 and R.sub.2 =H or alkyl, optionally substituted by alkenyl (2 to 4 C) or alternatively R.sub.1 and R.sub.2 form together a saturated heterocyclic ring containing 4 to 7 ring members and optionally containing another heteroatom such as O, S or N optionally substituted by alkyl, or R.sub.4 =H, R.sub.1 =H or alkyl and R.sub.2 and R.sub.5 together form an alkylene (3 to 4 C) radical and (i) either A=alkyl or phenyl which is unsubstituted or substituted by one or two substituents chosen from halogen, alkyl, alkyloxy, alkylthio, NH.sub.2, alkylamino, dialkylamino, NO.sub.2 or CF.sub.3 or alternatively A=pyridyl, benzyl or cycloalkyl (3 to 6C), Y=S, SO or SO.sub.2 or a radical: ##STR2## in which R.sub.6 =H or alkyl and R.sub.

Abstract: There is disclosed a process for the synthesis of para-nitrodiphenylamines via the Formanilide Process wherein the improvement is characterized in that a specific catalyst is utilized. More specifically, a zinc (II) compound (zinc in the plus two oxidation or valence state), is used as a catalyst in the preparation of para-nitrodiphenylamines via the formanilide process.

Abstract: A process for producing dimethylamine is provided, comprising reacting methanol and/or dimethylether and ammonia, in amounts sufficient to provide a carbon/nitrogen (C/N) ratio from about 0.2 to about 1.5, and at a temperature from about 250.degree. C. to about 450.degree. C., in the presence of a catalytic amount of a modified acidic zeolite selected from the group consisting of chabazite, erionite, ZK-5, and rho, the zeolite having been modified by treatment with one or more compounds containing at least one element selected from the group consisting of silicon, aluminum, phosphorus, and boron, to deposit thereon at least 0.05 weight percent of the element.

Abstract: Process for the production of a water-insoluble nitrogeneous organic base, from an aqueous solution of alkali metal bicarbonate and the base hydrochloride, according to which the solution (11) is treated with a complement of the base hydrochloride (12), and the resultant liquid (18) is treated with a basic agent (30) capable of decomposing the hydrochloride. The invention is applied to the regeneration of the amine in the process for the manufacture of sodium bicarbonate by the amines method.

Abstract: Substantially anhydrous hydrocarbyl-substituted chloramine is efficiently prepared by reacting a primary or secondary amine with a chlorinating agent selected from hypochlorous acid or chlorine monoxide in a non-aqueous reaction medium, without co-production of an amine hydrochloride salt.

Abstract: A process for eliminating N-nitrosamines, particularly N,N-dialkyl-N-nitrosamines and N-alkyl-N-aryl-N-nitrosamines from N-nitrosamine containing compositions through the addition of organic carboxylic acid halides. The process eliminates N-nitroso compounds without rearrangement to C-nitroso compounds.

Abstract: This invention relates to 2,2-dichloro-3,3-dimethylcyclopropylmethylamine, a novel compound which is useful as an agricultural and horticultural fungicide or as a synthetic intermediate for other cyclopropyl derivatives and other compounds, and to a process for production thereof.