Abstract: This application is directed to novel fluorinated polymers and prepolymers derived from mono-substituted oxetane monomers having fluorinated alkoxymethylene side-chains and the method of making these compositions. The mono-substituted fluorinated oxetane monomers having fluorinated alkoxymethylene side-chains are prepared in high yield by the reaction of a fluorinated alkoxides with either 3-halomethyl-3-methyloxetane premonomers or aryl sulfonate derivative of 3-hydroxymethyl-3-methyloxetane premonomers. Preparation of a mono-substituted 3-bromomethyl-3-methyloxetane premonomer via a simple, high yield process amenable to commercial scaleup is also disclosed. The fluorinated oxetane monomers of this invention can be readily homo/co-polymerized in the presence of a Lewis acid and polyhydroxy compounds to obtain hydroxy-terminated polyether prepolymers having fluorinated alkoxymethylene side chains.
Abstract: A novel organoboron polymer and its method of preparation is claimed. The organoboron polymer has a backbone having a repeating unit comprising at least one carboranyl group, at least two acetylenic groups, and one or more silyl or siloxanyl groups.
Type:
Grant
Filed:
November 7, 1994
Date of Patent:
July 14, 1998
Assignee:
The United States of America as represented by the Secretary of the Navy
Abstract: Antiperspirant stick compositions made from a solidifying agent which may include a gellant such as n-acyl amino acid amides, 12-hydroxystearic acid, esters of 12-hydroxystearic acid, amides of 12-hydroxystearic acid, and mixtures thereof; or a wax; a liquid base material including a non-volatile, non-polar emollient oil; an antiperspirant active; and a wash-off agent made of selected polyoxyethylene ethers; polyoxyethylene esters and diesters; and polyoxyethylene glyceryl esters and diesters. Such antiperspirant stick compositions exhibit improved wash-off performance, particularly with regard to the solidifying agent and the non-polar, non-volatile oils. These compositions are easily prepared by conventional techniques.
Abstract: Pharmaceutical preparation or system for activation of natural killer cells (NK cells), for example in order to treat tumors or virus infections, and which comprises a first composition containing interferon-.alpha. or analogues thereof, together with a second composition containing at least one substance with H.sub.2, or 5-HT.sub.1A, receptor agonist activity, for example, histamine or serotonin. The first and second compositions are either mixed in a preparation or furnished in separate doses.
Abstract: A foamable washing composition for hair and skin care contains: an insoluble silicone selected from silicone gums, silicone resins, and organomodified silicones comprising one or more thiol, carboxylate, .gamma.-hydroxypropyl, alkylcarboxylic acid, hydroxyalkylsulphonate, hydroxyalkylthiosulphate or hydroxyacylamino groups, and mixtures thereof; and 4-60% by weight of a compound of formula (I) which corresponds to structure (II), where R denotes a C.sub.8 -C.sub.24 alkyl or alkenyl radical or radical mixture, and x is 1-15; the weight ratio of the compound of formula (I) and the silicone being equal to or greater than 1.
Abstract: The present invention provides a process of treating damaged hair and a system of formulations for carrying out the process. Treatment according to the invention incorporates protein into the structure of damaged hair by the use of an aqueous solution including an acid and a positively charged electrolyte.
Abstract: An oil-based solid cosmetic composition comprising one or more polyoxyalkylene modified silicones and one or more conventional cosmetically acceptable oils, pigments, paints or a mixture thereof, is provided to give a cosmetic having excellent feel during use and prolonged beautiful make-up appearance.
Abstract: A method of treating human skin to decrease transepidermal water loss. A method of enhancing the substantivity of conditioning compounds applied to the skin. A film forming conditioning formulation which includes as an ingredient thereof an organosilicon compound is applied to the skin. The improvement resides in the utilization of a formulation which includes as the organosilicon compound a cyclic alkylmethyl polysiloxane.
Type:
Grant
Filed:
April 10, 1992
Date of Patent:
October 21, 1997
Assignee:
Dow Corning Corporation
Inventors:
Gary Edward Legrow, Regina Marie Malczewski
Abstract: A cosmetic hair-perming composition with a cosmetically acceptable medium containing at least one milk protein and/or milk protein hydrolysate and at least one keratin hydrolysate having a molecular weight of 100-200,000.
Abstract: The insect bait composition in the present invention is useful for feeding stimuli to induce insects, especially cockroaches, to preferably feed upon said bait composition, which will stimulate insect feeding and successfully compete with other food sources in the environment, said stimulant bait composition having one or more protein sources derived from poultry liver, silkworm pupae and hydrogenated soy protein.
Type:
Grant
Filed:
November 27, 1996
Date of Patent:
October 14, 1997
Assignee:
The Clorox Company
Inventors:
James Wolfe, Don Lesiewicz, Yashpal Mehra, Joseph Mares
Abstract: The compositions of the present invention are useful for the topical delivery of a wide variety of active ingredients. These compositions are particularly useful for treating conditions such as acne and its attendant skin lesions, blemishes, and other imperfections. These compositions are nonirritating to the skin and also provide improved skin feel benefits. These compositions can be in the form of leave-on products and products that are rinsed or wiped from the skin after use.
Type:
Grant
Filed:
July 24, 1995
Date of Patent:
September 9, 1997
Assignee:
The Procter & Gamble Company
Inventors:
David Michael McAtee, Lourdes Dessus Albacarys, Joseph Anthony Listro
Abstract: Xylobiose-containing skin preparations for external use are disclosed. Skin preparations for external use into which xylobiose may be incorporated include cosmetics such as clear lotions, milky lotions, packs and lip treatments, drugs or quasidrugs such as ointments and cataplasms, hair-care products such as rinses and hair conditions, and detergents such as hair shampoos and body shampoos. Xylobiose is typically contained in an amount of 0.0001-20 wt %, preferably 0.1-10 wt %, of the total amount of the skin preparation on a dry solids basis. The incorporation of xylobiose is effective not only in preventing the occurrence of stickiness, color change and malodor in the skin preparations but also in providing enhanced moisture retention and reducing excessive roughness and dryness of the skin and hair.
Abstract: Cosmetic or dermatological compositions comprising an oil-in-water type emulsion containing oily globules which are coated with a lamellar liquid crystal coating and are dispersed in an aqueous phase, in which each oily globule contains at least one lipophilic compound which is cosmetically or dermatologically active and is individually coated with a monolamellar or oligolamellar layer of at least one lipophilic surface-active agent, at least one hydrophilic surface-active agent, and at least one fatty acid, the coated oily globules having a mean diameter of less than 500 nanometers, preferably less than 200 nanometers, and the oily phase contains a basic agent in the dissolved state, exhibit good skin and hair penetration.
Abstract: Concentrated fungicidal compositions, in the form of water-dispersible granules are disclosed which contain:5 to 95% of phosphite-type active substance in solid or soildified form,0.1 to 8% of a wetting agent,0.3 to 15% of a dispersing agent,0 to 50% of a support. These granules have a particle size of between 0.1 mm and 10 mm.
Abstract: An antiarrhythmic agent which comprises as an active ingredient a carbostyril derivative of the formula: ##STR1## wherein R.sub.1 is hydrogen atom or a lower alkyl group, and R.sub.2 is a phenyl-lower alkyl group which has optionally 1 to 3 substituents of a lower alkoxy group on the phenyl ring, or a pharmaceutically acceptable salt thereof.
Abstract: The present invention provides an improved activator and method of utilizing same in applying durable protective coating on natural or artificial nails. The activator utilized for curing a gel component has a viscosity of approximately 10 to 5000 centipoise. The activator preferably includes a solvent, a polymerization initiator, and a viscosity modifying agent. The present invention also provides a method for applying a protective coating on a nail surface. The method includes the steps of applying an effective amount of adhesive on the nail surface, applying an effective amount of an activator having a viscosity of approximately 10 to 5000 centipoise on the nail surface, blending the adhesive and the activator together on the nail surface to form a blended mixture, and brushing the blended mixture over the nail surface.
Abstract: A drug delivery device is disclosed for delivering a drug to the intestine and the colon. The device comprises external means for delaying the delivery of drug in the stomach, and hydrophobic means for preventing the passage of fluid through the delay means.
Type:
Grant
Filed:
May 6, 1991
Date of Patent:
July 22, 1997
Assignee:
Alza Corporation
Inventors:
Jeremy Corwin Wright, George V. Guittard
Abstract: The invention relates to pharmaceutical compositions in the form of pleasant-tasting chewable tablets or chewable coated tablets which, besides the pharmaceutically active ingredient sucralfate, essentially contain at least one rapidly swellable physiologically acceptable gel former plus sugars or sugar substitutes.
Type:
Grant
Filed:
July 19, 1991
Date of Patent:
July 15, 1997
Assignee:
Merck Patent Gesellschaft Mit Beschrankter Haftung
Inventors:
Hans Peter Weckenmann, Hans-Gunther Schwamb
Abstract: A composition for delaying release of an active component into an aqueous fluid is taught which includes a capsule that swells in the presence of an aqueous fluid allowing moisture to enter the capsule into contact with a capsule decomposing agent activated by the entering moisture such that the agent decomposes the capsule sufficiently to release the active agent at a predetermined delayed time after the capsule contacts the aqueous fluid. A preferred capsule composition is gelatin and decomposing agents are a proteolytic enzyme or a salt that effects the osmotic gradient of the system. The controlled release composition of the invention is preferably utilized in a soft contact lens disinfecting system wherein a solution of hydrogen peroxide disinfects the lenses followed by neutralization of residual hydrogen peroxide wherein release of the neutralizing agent is delayed by means of the capsule proteolytic enzyme or salt composition.
Abstract: There is disclosed a self-dispersing curable epoxy resin composition comprising the addition product of reactants comprising (a) 1.0 reactive equivalent of an epoxy resin, (b) from about 0.40 to 0.95 reactive equivalents of a polyhydric phenol, and (c) from about 0.005 to 0.5 reactive equivalents of an amine-epoxy adduct comprising the addition product of reactants comprising 1.0 reactive equivalent of a polyepoxide and from about 0.3 to 0.9 reactive equivalents of a polyoxyalkyleneamine having the structural formula:R.sub.1 --O--R.sub.2 --CH.sub.2 CH(R.sub.3)--X--R.sub.4 --NH2wherein:R.sub.1 designates a monovalent organic radical selected from the group consisting of C.sub.1 to C.sub.12 aliphatic, alicyclic or aromatic hydrocarbons, andR.sub.2 represents a polyoxyalkylene chain having the structural formula:(CH.sub.2 --CH.sub.2 --O).sub.a --(CH.sub.2 --CH(R.sub.5)--O).sub.bwherein:R.sub.5 is a monovalent organic radical selected from the group consisting of C.sub.1 to C.sub.