Abstract: A method of treating viral infection comprises the step of administering to a patient harboring a disease-inducing virus other than HIV-1, the virus being one for which an intracellular thiol deficit causes or exacerbates expression of viral genetic information by transcription, translation or viral replication, such as human rhinovirus, an amount effective to inhibit transcriptional or translational expression of genetic information or replication of the virus, of an N-(C.sub.1-4)-acylcysteine, such as N-acetyl cysteine, or a pharmaceutically acceptable salt thereof. Prevention of disease symptoms and reduction of their severity results from the foregoing treatment. Combination of N-(C.sub.1-4)-acylcysteine or its salt with another antiviral drug or drug for alleviating symptoms of viral infection provides additional therapeutic benefits.
Type:
Grant
Filed:
October 17, 1995
Date of Patent:
December 3, 1996
Inventors:
Leonard A. Herzenberg, Leonore A. Herzenberg
Abstract: Epoxy-containing compounds which are essentially free of organic halides are prepared by (I) reacting an allyl derivative of an active hydrogen-containing compound with (II) a peroxygen-containing compound. The epoxy-containing compounds are useful in coatings, castings, laminates etc.
Abstract: Novel epoxy acrylates and carboxyl group-containing epoxy acrylates of formulae II and III of the claims that are relatively highmolecular and are chemically crosslinkable can be used in photoresist formulations with the additional use of highly polymerized polymer binders. Such resist formulations are used in particular in the field of printed circuit boards and printing plates, are applicable from aqueous medium, are almost tack-free and have very good edge coverage, especially on conductors.
Type:
Grant
Filed:
June 28, 1994
Date of Patent:
November 19, 1996
Assignee:
Ciba-Geigy Corporation
Inventors:
Martin Roth, Roger Salvin, Kurt Meier, Bernhard Sailer, Rolf Wiesendanger
Abstract: A functionalized polymer according to the invention includes a polymer molecule having the general formula AYLi where A is a cyclic amine-containing radical having the general formula ##STR1## R.sub.1 is a divalent alkylene, an oxy- or amino-alkylene, or substituted alkylene having from 6 to about 20 carbon atoms; R.sub.2 is a linear-, branched-, or cyclo-alkylene having from about 2 to about 20 carbon atoms; and Y is a divalent polymer radical and Li is a lithium atom bonded to a carbon atom of Y.
Type:
Grant
Filed:
February 1, 1995
Date of Patent:
November 12, 1996
Assignee:
Bridgestone Corporation
Inventors:
David F. Lawson, Thomas A. Antkowiak, James E. Hall, Mark L. Stayer, Jr., John R. Schreffler
Abstract: An aldimine oxazolidine compound having the formula: ##STR1## wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are, individually, a hydrogen atom, a methyl or methylol group, an ethyl or ethylol group, a straight chain or branched chain alkyl or alkanol group, a cycloalkyl group, or an aryl group, including groups substituted by nitro, halogen, thiol and amino functional groups, such that when R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are hydrogen atoms, R.sub.3 and R.sub.4 are not hydrogen atoms; m and n are integers of one to five; and X is zero or a --R.sub.9 --Y--R.sub.10 -- group, wherein R.sub.9 and R.sub.
Abstract: A liquid coating composition particularly adapted for coating cans. The composition comprises a curable, hydroxyl functional block copolymer which is the reaction product of a 1,2-epoxy resin and a carboxyl functional polyester resin, and a hydroxyl-reactive crosslinking agent providing desirably at least 2.0 equivalents of hydroxyl reactive functional groups per hydroxyl equivalent of the block copolymer. The block copolymer desirably has a number average molecular weight in the range of 7000 to 30,000. Also disclosed is a method for formulating a coating composition utilizing craze resistance testing over an aging period to enable the choice of the quantity of curing agent to be used in the coating composition.
Abstract: Superabsorbent solid organic polymers which absorb over 100 times their weight in water are used in aquatic environment insect population control compositions. Methods for using the superabsorbent polymer insecticidal delivery agents for the control of aquatic environment insect populations, including mosquito population control methods, in an area needing aquatic environment insect population control treatment or in a dry area that is expected to need aquatic environment insect population control, are described.
Abstract: A low-sensitizing wound cleanser product is provided for use in rinsing contaminants from injuries. The cleanser includes a combination of specially selected non-irritating ingredients that include a water and aloe vera carrier portion, an emollient portion, a hydroxyquinoline antimicrobial portion, a surfactant portion, and a preservative portion.
Abstract: A process for permanently reshaping hair consists of applying an amino compound, an amidothiol compound or a salt of an amino compound or an amidothiol compound as a reducing agent to open the keratin bonds of hair and reforming the bonds using an oxidizing composition or aerial oxygen, wherein prior to or simultaneously with the application of the reducing agent, at least one alkali metal, alkaline-earth metal or ammonium bromide is applied to the hair as a doping agent for the reducing agent. A composition for carrying out the process contains at least one amino compound, amidothiol compound or a salt of an amino compound or an amidothiol compound as a reducing agent, at least one alkali metal, alkaline-earth metal or ammonium bromide as a doping agent for the reducing agent, and a suitable cosmetic vehicle. This process and composition enable improved qualities to be obtained in the permanent reshaping of hair, in particular improved curling.
Type:
Grant
Filed:
May 18, 1994
Date of Patent:
October 15, 1996
Assignee:
L'Oreal
Inventors:
Fr ed eric Leroy, G erard Malle, Agn es Burande, Yolanda Duvault
Abstract: A composition of matter having a clay porous granule and a polyurethane matrix formed from the polymerization of a polyol and a polyisocyanate and held within the pores of the granule and having uniformly distributed throughout the polyurethane matrix a liquid material, for example, a pesticide and a method for loading a porous granule with the polyurethane and the liquid material by:(a) spraying a porous granule with a liquid composition comprising a polyol, a polyisocyanate and a liquid material to be retained in the porous granule, and(b) polymerizing the polyol and the polyisocyanate to form a polyurethane matrix polymer which has the liquid materials uniformly distributed throughout the polyurethane matrix.
Abstract: Organic polymer surfaces are modified by contacting such surfaces with a haloester compound and a cationic compound of having a pK.sub.a >5. Preferably the organic polymer is selected from the group consisting of polyesters, aromatic polyamides, and graphitic polymers and the contacting is conducted at an elevated temperature.
Type:
Grant
Filed:
October 26, 1995
Date of Patent:
October 8, 1996
Assignee:
Hoechst Celanese Corporation
Inventors:
Norman S. Anderson, Albert L. Promislow
Abstract: A method for removing cured sulfur-containing polymer sealants from surfaces is disclosed. The method comprises applying to the surface a sealant remover comprising at least about 50 wt. % of a pyrrolidone, especially N-methyl-2-pyrrolidone, and allowing the cured sulfur-containing polymer and the remover to remain in contact until the cured sulfur-containing polymer is loosened and can be easily removed from the surface. The method of the invention enables fast, effective removal of the sulfur-containing polymer sealants commonly used in the aerospace, construction, and insulating-glass industries.
Abstract: A room temperature curable silicone composition, comprising (A) 100 parts by weight of an organopolysiloxane each of both ends of which has one hydroxyl group, (B) 0.2 to 40 parts by weight of at least one compound selected from the group consisting of hydrolyzable silanes having 2 to 4 hydrolyzable groups and their partial hydrolysis-condensation products, (C) 1 to 100 parts by weight of a modified diorganopolysiloxane of which both ends have at least one group selected from the group consisting of a hydrogen atom, a substituted monovalent hydrocarbon group and alkoxy group having 1 to 10 carbon atoms, an unsubstituted hydrocarbon group and alkoxy group having 1 to 10 carbon atoms, and a hydroxyl group and that has a silicon-bonded modifying group made up of a substituted or unsubstituted monovalent organic group with 6 or more carbon atoms, and (D) a filler and a cured product thereof. A cured product good in peeling properties can be obtained.
Abstract: A non-crosslinked endblocked polymer, comprising a preformed aqueous emulsion having a plurality of silanol-terminated polydiorganosiloxane particles, an endcapping silane having the formula R.sub.3 SiX where X is a hydrolyzable group, R is an alkyl group consisting of 1 to 7 carbon atoms, and an organotin catalyst. The composition results in a non-crosslinked polymer, unlike the polymers described in the prior art. It has been found that adding an endblocking silane having only one hydrolyzable group to a preformed polydiorganosiloxane emulsion results in endblocked polydiorganosiloxane molecules free of crosslinks between the polydiorganosiloxane chains.
Abstract: An aluminum-nitrogen polymer is prepared by reacting an organic nitrile with a dialkylaluminum hydride to form an organoaluminum imine, and heating the imine to a temperature of 50.degree. to 200.degree. C. for at least 2 hours. The polymeric product can be subjected to an additional heat treatment to form a more highly cross-linked polymer. After either heat treatment the polymeric product can be further reacted with a primary amine or ammonia. The organoaluminum imine as well as the aminated or non-aminated polymers can be pyrolyzed to form an aluminum nitride-containing ceramic.
Abstract: The invention relates to salts of pyromellitic acid which comprise 1 mol of pyromellitic acid and 0.5. to 2 mol of a guanidine of the following composition: ##STR1## in which R, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are identical or different radicals from the group consisting of hydrogen, alkyl, cycloalkyl and aromatic hydrocarbon residues having 1 to 8 carbon atoms, and R.sup.1 and R.sup.2 and R.sup.3 and R.sup.4 may form a joint ring which may contain an oxygen atom as heteroatom. Also claimed are the preparation of the salts and their use for matt epoxide and hybrid powder coatings.
Abstract: This application is concerned with room temperature vulcanizing compositions useful as mould making materials which are formed by mixing an alpha, omega dihydroxy polysiloxane, a condensation polydimethylsiloxane, catalyst and a crosslinking agent which comprises a tri- or tetra-alkoxy silane or siloxane in which the alkoxy groups contain more than two carbon atoms. Moulds made with these materials on epoxy masters show improved usage; the improvement is related to the size of the alkoxy "leaving group" and the proportion of crosslinker and condensation catalyst.
Abstract: The subject-matter of the present invention is to solve the technical problem resulting from the instability in air of polysilanes. For this purpose, it proposes a polysilane-based composition, used particularly for producing silicon carbide, comprising:polysilane chains capable of being degraded by oxidation and the formation of polysiloxane-type products and/or polysilane chains suitable for being bound together directly by a reaction between Si--H and Si--X radicals, and/or indirectly through the intermediary of a crosslinking additive and by a reaction between A--X and A--H radicals, X being an olefin radical, preferably comprising 1 to 18 carbon atoms and, more preferably still, being constituted by a vinyl radical (Vi:--CH.dbd.CH.sub.2), A being an organic, organosilicic or silicic radical;and at least one antioxidant system.
Abstract: An infiltration-type water-based organosilicon composition having excellent performance as a water absorption preventer for construction materials and being stable as an emulsion, which is prepared by emulsifying alkylalkoxysilane and/or its condensate in water in the presence of (a) an anionic emulsifier and/or nonionic emulsifier, (b) a thickener, and (c) an alkaline compound.
Abstract: A conductive polymer comprises a silicon-containing polymer having, in the main chain thereof, Si--Si bonds or both Si--Si bonds and C--C multiple bonds, and ferric chloride doped in said polymer through vapor phase doping. A method for preparing such a conductive polymer is also described.