Abstract: An automatic medication injection device that provides a user with audible notice of injecting progress. The device in one form includes a plurality of sound elements located on drive mechanism portion that inserts within a barrel of a container of medication to advance a sealing plunger of that container. The device also includes at least one actuating element movable axially with the container of medication within the device housing, which at least one actuating is element arranged to engage the plurality of sound elements to generate audible notices as the advancing portion moves past the at least one actuating element when advancing the sealing plunger for an injection.

Abstract: A safe insulin pen needle has a structure effectively circumvents the risk of the needle head protection failure caused by the rotation of the insulin pen during the needle pulling process by some users through a first check flange on one side of a first initial fixing position matched with a first elastic clamping jaw. The safe insulin pen needle effectively circumvents the safety risk that the needle tail tends to damage the user through the needle tail protection structure and, at the same time, effectively circumvents the risk that the needle tail protector will rotate and thus the needle tail protection will fail during the separation of the insulin pen from the insulin pen needle through a second check flange on one side of a second initial fixing position matched with a second elastic clamping jaw.

Abstract: Steerable medical devices and methods of use. In some embodiments, the steerable medical devices can be steered bi-directionally. In some embodiments the steerable medical devices include a first flexible tubular member and a second flexible tubular member secured together at a location distal to a steerable portion of the steerable medical device.

Abstract: A feeding system for medical patients comprises a storage assembly, dispensing assembly, and extension set including, in part, a reservoir, a pump, a feeding tube, a check valve and an adapter. The reservoir is configured to hold at least one feeding of nutritional substance. The dispensing assembly is connected to the storage assembly and pumps the at least one feeding of nutritional substance from the reservoir to the feeding tube connected to an outlet of the pump. The check valve unit is connected to a second end of the feeding tube by means of a check valve connection point and is configured to allow the flow of nutritional substance in only one direction. The at least one feeding of nutritional substance is passed through the adapter unit connected to the check valve unit.

Abstract: A distribution assembly having a syringe having a body with a tip supporting a needle having a bevel, and a removable syringe needle protection device. The protection device has a flexible cap defining an inside cavity defined by a side wall and by a distal solid end wall, and when in the protection position, receiving the bevel of the needle in airtight manner. The side wall includes an annular bead provided with at least one slot extending across the bead in a longitudinal direction, the bead, when in the protection position, co-operating in airtight manner with the tip of the syringe. The cavity of the cap is dimensioned so that when the protection device is removed from the syringe, the cavity is connected to the atmosphere via the slot before the bevel of the needle becomes connected to the cavity.

Abstract: Disclosed herein are steerable catheter assemblies and methods of steering catheters. Some embodiments include a catheter with first and second oppositely disposed pull wires and third and fourth oppositely disposed pull wires that flex the catheter, a control handle coupled to the catheter, a first follower connected to the first pull wire, a second follower connected to the second pull wire, a first driver coupled to the control handle and coupled to the first and second followers, a third follower connected to the third pull wire, a fourth follower connected to the fourth pull wire, and a second driver coupled to the control handle and coupled to the third and fourth followers. Rotation of the first driver moves the first and second followers in opposite directions. Rotation of the second driver moves the third and fourth followers in opposite directions.

Abstract: An apparatus and method for the treatment of intravascular medical conditions is provided. The device comprising a handle assembly, an expandable portion defined by a plurality of struts oriented along a longitudinal axis and a tip member affixed to a distal end of the struts. The struts are moveable between a collapsed and an expanded position. A catheter tube extends from the handle assembly to the expandable portion. An elongate member is disposed within the catheter tube and is in communication with the handle assembly and the tip member.

Abstract: An injection device comprises a housing containing a cartridge, a needle holder including an injection needle, and a cap. The cap is removably engaged with the housing. The injection device also comprises a translating mechanism configured such that linear distal movement of the cap causes proximal movement of the needle holder such that the injection needle pierces the cartridge.

Abstract: In general, medical sheath systems that can employ retainer devices having a plurality of channels configured to retain a sheath assembly in one or more curved configurations are described. In one embodiment, a retainer device may releasably retain a curvable tube of the sheath assembly in any of multiple curved configurations that range, for example, in selectable increments between 0° to 180°.

Abstract: Finger control handles for conventional syringes are disclosed. The finger control handles may be configured to be assembled with a hand-held syringe, to be secured in place on a proximal portion of the barrel of the syringe and, when secured in place, to rotate freely about a circumference of the proximal portion of the barrel of the syringe. Systems that include the finger control handles and a hand-held syringe that is configured to capture the finger control handles are also disclosed, as are various methods of use, including methods for assembling the finger control handles with the syringe and methods for connecting the syringe to an elongated medical instrument, such as a catheter.

Abstract: Injection device of fluid product (100) comprising a syringe body (101) and a needle (110) fixed in an axial end projection (102) of the syringe body, said injection device comprising a needle protection device (200), said protection device being, in a storage position, fixed on said injection device, said protection device being removable from said injection device, said protection device comprising an inner body (210) made of substantially supple and/or deformable material and an outer body (220) made of substantially rigid material, said inner body (210), in a storage position, sealingly closing the distribution orifice (111) of said needle (110) and sealingly cooperating with said injection device (100), and said outer body (220) in a storage position, cooperating with said injection device (100) to fix said protection device (200) onto said injection device (100), characterized in that said outer body (220) comprises a fixing part (228) fixed to said injection device (100) and a protection part (229) fix

Abstract: The present disclosure relates to a dialysis device (1), more particularly a microdialysis device for the sampling of substances from the surface of a body organ. The device is particularly useful in the context of the monitoring of a moving organ, such as a beating heart, as the device comprises attachment means (2) allowing for a flexible and reliable attachment thereto. Furthermore, the microdialysis device provides for an efficient exchange of substances, such as metabolic substances, between the organ and the dialysis fluid through a semi-permeable material forming part of the device. There is also provided a method encompassing the device of the disclosure.

Abstract: The invention relates to an adapter element for fastening a needle element to a syringe base body, the adapter element having a base body which is configured and provided for receiving the needle element, the base body having at least one through-opening for passing the needle element through and for fixing it, and the base body being configured and provided for being fastened to the syringe base body.

Abstract: An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure. The apparatus comprises a dilution syringe for removal of a portion of peritoneal fluid from the peritoneal cavity. A glucose bag comprises glucose concentrate at a concentration of 30%. A small amount of glucose concentrate is mixed with the dilution fluid in the dilution syringe in order to dilute the glucose concentrate to below 3% concentration. Then, the mixture is filled into the peritoneal cavity from the dilution syringe in order to replenish the glucose in the peritoneal cavity for maintaining a substantially constant glucose concentration in the peritoneal cavity. In addition, peritoneal fluid is intermittently removed from the peritoneal cavity for counteracting increased intraperitoneal fluid volume and increased intraperitoneal pressure due to ultrafiltration. A UF bag is arranged for receiving such surplus peritoneal fluid. A glucose syringe may be arranged for metering the glucose concentrate.

Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

Abstract: An apparatus for discharging a dose of a fluid substance to an animal, the apparatus including: a delivery assembly adapted to discharge the dose of the substance to the animal; and a control system operatively associated with the delivery assembly so as to selectively operate the delivery assembly, wherein the control system is adapted to measure the discharge of the fluid substance from the delivery assembly such that the dose is discharged when the delivery assembly is operated.

Abstract: A method, including ejecting irrigation fluid from a distal end of a probe so as to irrigate tissue, and receiving, over a period of time, initial signals indicative of respective temperatures of the distal end, from a temperature sensor in the distal end. The method also includes formulating from the initial signals a temperature range between upper and lower temperature thresholds and, when a further signal from the temperature sensor, received subsequent to the period of time, is indicative of a further temperature above the upper temperature threshold, raising an alarm that a bubble is present in the irrigation fluid.

Abstract: A syringe including a barrel, a plunger moveably arranged within the barrel and a plunger rod for driving the plunger, and an engagement member arranged at the barrel to engage with a grooved surface on the plunger rod. This will create feedback given to a user as the plunger rod is moved relative to the barrel for driving the plunger within the barrel. The barrel and the engagement member are arranged relative to each other such that the engagement member, due to the engagement with the grooved surface of the plunger rod, will move solely in a direction generally perpendicular to a longitudinal direction of the plunger rod as the plunger rod is moved relative to the barrel.

Abstract: Steerable catheters include cam and follower mechanisms that provide independent control of catheter flex magnitude and catheter flex direction to provide improved steerability of an attached catheter. In certain embodiments, the steerable catheter assemblies include two or more pull wires that flex the catheter, and a control handle coupled to the catheter having a direction control and a magnitude control, both of which are operably coupled to the two or more pull wires by the cam and follower mechanism. In embodiments disclosed herein, the cam and follower system can be modified to achieve particular catheter control.

Abstract: A dialysis catheter is provided. A first lumen extends through a first tubular member from a proximal portion to a distal portion, and a first orifice at the distal portion provides an opening through the first tubular member to the first lumen. The first tubular member further includes an inflation lumen extending longitudinally at least partially through a length of the first tubular member. A balloon is operably connected to an outer surface of the first tubular member proximal to the first opening, is in fluid communication with the inflation lumen. A second tubular member has a proximal portion connected to the outer surface of the first tubular member. A distal portion of the second tubular member is connected to the balloon wall. A second lumen extends through the second tubular member, and a second orifice provides an opening through the second tubular member at the distal portion.