Patents Examined by John W. Rollins, Jr.
  • Method of promoting growth and enhancing feed efficiency in meat producing animals
    Patent number: 4443470
    Abstract: A method of promoting growth and enhancing feed efficiency in meat producing animals. The 6' esters of zearalanol are effective growth promoting agents in meat producing animals, particularly ruminants, when implanted subcutaneously in said animals to obtain a controlled release of the compositions.Included in this group of compositions are: zearalanol 6'-butyrate; zearalanol 6'-decanoate; zearalanol 6'-hexanoate; zearalanol 6'-laurate; zearalanol 6'-trichloroacetate; and zearalanol 6'-trifluoroacetate.
    Type: Grant
    Filed: September 3, 1981
    Date of Patent: April 17, 1984
    Assignee: International Minerals & Chemical Corp.
    Inventors: Edward B. Hodge, Glen W. Wolfrom
  • Veterinary composition and method of using same
    Patent number: 4443437
    Abstract: This invention relates to a topical veterinary composition and a method of using same for the treatment of flesh wounds or lacerations or fistulas in animals and to promote the healing thereof. The composition comprises as the active ingredient tall oil either per se or as a topical veterinary ointment comprising the active ingredient in admixture with a suitable carrier and/or antiseptic.
    Type: Grant
    Filed: September 23, 1982
    Date of Patent: April 17, 1984
    Inventors: Walter G. Prokosch, Robert L. Marshall
  • Snake bite therapy
    Patent number: 4439443
    Abstract: A method of reducing local hemorrhage and tissue necrosis resulting from the bite or sting of a venomous animal whereby an envenomated mammal is treated with a compound of the formula ##STR1## or a corresponding disulfide wherein n is 1, 2 or 3; Z is O, S or NH; R is H, a straight or branched chain lower alkyl group of from 1 to 4 carbon atoms, hydroxy, a straight or branched chain lower alkoxy group of from 1 to 4 carbon atoms, fluoro, chloro, bromo, iodo or trifluoromethyl; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 2, 1982
    Date of Patent: March 27, 1984
    Assignee: Richardson-Merrell Inc.
    Inventor: Eugene L. Giroux
  • Adjuvant for stimulating production of lymphocytes
    Patent number: 4431639
    Abstract: This invention relates to an adjuvant effective for stimulating the production of lymphocytes in the circulating blood of a mammal which adjuvant is an extract from Atractylis lyrata s. et z.
    Type: Grant
    Filed: November 20, 1981
    Date of Patent: February 14, 1984
    Inventor: Dae-Eun Kim
  • Gastric cytoprotection with heterocyclic sulfonamides
    Patent number: 4424227
    Abstract: The present invention provides a method for gastrointestinal cytoprotection using a class of heterocyclic sulfonamides.
    Type: Grant
    Filed: May 5, 1982
    Date of Patent: January 3, 1984
    Assignee: The Upjohn Company
    Inventor: Andre Robert
  • Method of treating coronary heart disease with imidazo(4,5-B)pyridines
    Patent number: 4421755
    Abstract: Pharmaceutical compositions containing, as an active ingredient, a compound of the formula ##STR1## wherein R.sub.1 is alkoxy of 1 to 4 carbon atoms, and R.sub.2 is (alkyl of 1 to 4 carbon atoms) sulfinyl, or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same for the treatment of coronary heart diseases or coronary spasms.
    Type: Grant
    Filed: February 18, 1982
    Date of Patent: December 20, 1983
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Lothar Benedikter, Eberhard Kutter
  • Process for producing interferon inducers
    Patent number: 4421746
    Abstract: An interferon inducer is produced by extracting a tissue of a plant belonging to the Gound family selected from the group consisting of Benincasa, Cucurbita, Citrullus, Cucumia, Lagenaria, Luffa, Mormordica, Tricsanthes and their variants by water extraction at a temperature of from ambient to the boiling point of the extraction mixture, forming a supernatant from the extracted solution, fractionating the supernatant to yield fractions containing the interferon inducer and recovering same.
    Type: Grant
    Filed: June 28, 1982
    Date of Patent: December 20, 1983
    Assignee: The Kitasato Institute
    Inventors: Yasuhiko Kojima, Sadao Tamamura, Seishi Konno, Takashi Hashimoto
  • Protection of lyophilized betalactams from color formation
    Patent number: 4418058
    Abstract: A stable preparation of a lyophilized .beta.-lactam antibacterial containing a 7.beta.-(.alpha.-carboxy-.alpha.-arylacetamido)-7.alpha.-methoxy-3-heteroc yclic thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid (I) alkali metal salt as the antibacterial component and a sugar or sugar alcohol compound as the stabilizing agent.
    Type: Grant
    Filed: June 12, 1981
    Date of Patent: November 29, 1983
    Assignee: Shionogi & Co., Ltd.
    Inventors: Eizo Hirai, Kazuhiro Shima
  • Protozoacidal activity of phenothiazines
    Patent number: 4407800
    Abstract: A method of treating or protecting against parasitic diseases caused by members of the protozoan family Trypanosomatidae comprising administering to a mammal a phenothiazine drug. This represents a new use of the phenothiazine compounds.
    Type: Grant
    Filed: November 2, 1981
    Date of Patent: October 4, 1983
    Assignee: University of Virginia Alumni Patents Foundation
    Inventors: Richard D. Pearson, Erik L. Hewlett
  • Biologically active extracts from Maytenus nemerosa (Eckl and Zeyh) Morais (Celastraceae) South Africa and method of obtaining same
    Patent number: 4405613
    Abstract: This invention provides an extract from the plant Maytenus nemerosa (Eckl & Zeyh) Morais (Celastroceae) South Africa and a method of obtaining same. The extract is obtained by subjecting the plant to a series of extraction steps with a plurality of solvents having different polarities. In each extraction step, the solvent used has a polarity higher than that used in the preceding extraction step. All extraction steps are conducted at room temperature. The extracts have been found to possess biological activity.
    Type: Grant
    Filed: July 23, 1982
    Date of Patent: September 20, 1983
    Inventor: Sidney M. Hecht
  • Fungicidal composition for agriculture and horticulture and its use
    Patent number: 4378355
    Abstract: The present invention relates to a fungicidal composition for agriculture and horticulture comprising at least one adjuvant and, as an effective component, in effective amounts, N-(1-n-butoxy-2,2,2-trichloroethyl) salicylamide and one member selected from the group consisting of (1) pentachloronitrobenzene and (2) tetrachloroisophthalonitrile.This composition is useful to control soil borne plant diseases such as clubroot disease of Cruciferae crops, black scurf of potatoes and damping-off of cucumber and tomato seedlings.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: March 29, 1983
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Taizo Nakagawa, Kaoru Ohmori