Abstract: Creosote has a novel pharmaceutical efficacy for treatment of various diseases with diarrhea. The medicament according to the present invention usually contains creosote, coptidis rhizoma, glycyrrhizae radix pulverata, cyperi rhizoma, auranti pericarpium and glycerinum, and it especially consists of 400 mg % of creosote, 200 mg % of coptidis rhizoma, 200 mg % of glycyrrhizae radix pulverata, 150 mg % of cyperi rhizoma, 200 mg % of auranti pericarpium and 100 mg % of glycerinum in each 9 pills.
Abstract: A pharmaceutical composition is being described that contains pharmacologically acceptable magnesium compounds, etofylline, vitamin A and vitamin C. It is especially suitable for treatment of inflammatory changes of the bronchial mucosa.
Abstract: A method for obtaining ovipositional disruption of navel orangeworm. The air of nut orchard area, e.g., almonds, where egg-laying by the moth of the navel orangeworm is expected is permeated, as by spraying, by a composition of matter incorporating as an active ingredient as effective amount of crude almond oil. The composition may be a water emulsion of crude almond oil or may be a water emulsion of a wettable powder formulation containing appreciably equal amounts of crude almond oil and ground almond press cake.
Type:
Grant
Filed:
December 4, 1984
Date of Patent:
August 12, 1986
Assignee:
The Regents of The University of California
Inventors:
Robert A. Van Steenwyk, William W. Barnett
Abstract: A process for the preparation of a skin-regenerating or skin-protecting pharmaceutical composition is disclosed wherein the flower, root, fruit or cortex of a plant selected from the group consisting of Fugaceae, Caesalpiniaceae, Chenopodiaceae, and Rosaceae is extracted with ethanol at a temperature of 0.degree. to 50.degree. C. The obtained plant extract is purified and the dry substance content thereof is adjusted to 0.01 to 0.1% by adding more of the ethanol.
Abstract: The effect of carcinogens is negated in mice by a synergistic diet comprising a source of selenium, butylated hydroxytoluene or butylated hydroxyanisole, and .beta.-carotene.
Abstract: This invention relates to the use of various 2-acetylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom in the treatment of viral infections. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.
Type:
Grant
Filed:
March 30, 1982
Date of Patent:
June 24, 1986
Assignee:
The United States of America as represented by the Secretary of the Army
Inventors:
Charles Shipman, Jr., Daniel L. Klayman, Sandra H. Smith, John C. Drach
Abstract: The invention relates to a process and a preparation for deactivating viruses inside living human and animal organisms by application of a terpene obtainable from aromatic plants by steam distillation. The terpenes cited are: black pepper oil, cinnamon flower oil, cardamom oil, linallyl acetate, cinnamic aldehyde, safrol, carvon and cis/trans citral.
Type:
Grant
Filed:
February 28, 1985
Date of Patent:
June 17, 1986
Assignee:
Chimicasa GmbH
Inventors:
Erich Wolf, Andreas Lembke, Rolf Deininger
Abstract: The invention relates to the preparation of 3-trifluoromethyl- and 2,5-dimethyl-4'-hydroxy-.alpha.-ethyl-benzhydrol. Both compounds have so far been described only as metabolites of corresponding benzhydrol derivatives containing no hydroxyl group. Neither their physico-chemical characteristics nor their manufacturing processes have been disclosed in the known publications.3-Trifluoromethyl- and 2,5-dimethyl-4'-hydroxy-.alpha.-ethyl-benzhydrol are suitable for the treatment of acute ethanolic intoxication. Accordingly, another aspect of the invention is a pharmaceutical composition containing one of these compounds as active ingredient.
Type:
Grant
Filed:
December 27, 1983
Date of Patent:
June 3, 1986
Assignee:
Richter Gedeon Vegyeszeti Cyar RT
Inventors:
Edit Toth, Jozsef Torley, Gyorgy Fekete, Laszlo Szporny, Laszlo Vereczkey, Eva Palosi, Imre Klebovich, Pal Vittay, Sandor Gorog, Istvan Hajdu
Abstract: A composition for the prevention of and relief of muscular aches and pains, aches caused by tension such as headaches and backaches and aches and pain caused by inflamed muscles and inflammation surrounding muscles. The composition comprises an aqueous extract of a heated composition of water and capsicum and which can contain slippery elm and myrrh gum. The composition is a non-greasy, odorless, free of sedating drugs, topically applied extract valuable for the relief and prevention of minor aches and pains.
Abstract: A method for inhibiting the secretion of stomach acid in vertebrate animals. The method comprises contacting the lumen side of the stomach with a compound which interferes with the acid secretion mechanism yet cannot permeate the lining of the stomach. The compound has a molecular weight of less than 1,200 and at least ten percent of the molecular weight of the compound is due to the molecular weight contribution of secondary amine nitrogen. The invention also includes an ingestible product for inhibiting the secretion of stomach acid in vertebrate animals. The product is ingested so that it is contacted with the lumen side of the stomach to interfere with the acid secretion mechanism without permeating the lining of the stomach. The product contains a compound which has a molecular weight of less than 1200, at least ten percent of the molecular weight of the compound being due to the molecular weight contribution of secondary amine nitrogen.
Type:
Grant
Filed:
October 29, 1982
Date of Patent:
May 27, 1986
Assignee:
Research Foundation of State University of New York
Abstract: Herpes simplex, herpes varicella, and herpes zoster are treated by topical application of a composition comprising an effective amount of aloe vera and kelp. The composition can additionally contain an effective amount of jojoba oil.
Abstract: Water-based cosmetic compositions for lubricating the skin for shaving. The cosmetic compositions constitute thin lotions and include a mixture of effective amounts of water, a gel former and binding agent, a gelling agent with skin conditioning properties and an emollient. Titanium dioxide may be used to import color to the cosmetic composition.
Type:
Grant
Filed:
October 4, 1982
Date of Patent:
April 29, 1986
Assignee:
White Laboratories, Inc.
Inventors:
Thomas E. Newberry, Jr., Ralph R. Uhrmacher, Robert K. Arblaster
Abstract: A new lipophobic fraction has been prepared by the extraction of camomile flowers with boiling ethyl or methyl alcohol, which can contain up to 30% water, letting the alcoholic solution evaporate to obtain a residue and washing the obtained residue with the appropriate organic solvents.This fraction is particularly free of any of the camomile extract components that are volatile in steam current and the fraction has a strong bacteriostatic and bactericidal action.Therapeutic compositions having antibacterial action were prepared, using the lipophobic fraction of the camomile extract prepared as described above.
Type:
Grant
Filed:
June 1, 1983
Date of Patent:
April 22, 1986
Assignee:
Bonomelli S.p.A.
Inventors:
Aurelia Tubaro, Roberto Della Loggia, Elena Banfi, Marina Cinco, Claudio Redaelli
Abstract: A pharmaceutical composition is provided herein containing as a key ingredient 4-carbamoyl-imidazolium-5-oleate of the formula (I) ##STR1## its salt or hydrate thereof, and one or more of a sulfur compound capable of producing at least one of the ions selected from HSO.sub.3.sup.--, SO.sub.3.sup.2-- and S.sub.2 O.sub.5.sup.2--. The sulfur compounds prevent discoloration of the composition.The stabilization against coloration is further enhanced by the presence of L-cysteine hydrochloride. The solubility of the compound (I) can be further enhanced by the presence of a basic substance. The active ingredient is known as a therapeutic agent for the treatment of such diseases as rheumatism and nephritis.
Abstract: Water-soluble extract of sonically induced disintegration of Actinobacillus actinomycetemcomitans causes inhibition of growth and metabolism of bacteria associated with plaque formation. The water-soluble extract contains factors which are specifically inhibitory to these organisms.
Type:
Grant
Filed:
March 13, 1984
Date of Patent:
April 1, 1986
Assignees:
Colgate-Palmolive Co., University of Pennsylvania
Abstract: A pharmaceutical composition for the treatment of osteopathias is described which contains an effective amount of the active ingredient 6-amino-1-hydroxyhexane-1,1-diphosphonic acid or a pharmaceutically acceptable salt, ester, or a chelation complex with copper and inert carriers. The compositions are suitable for oral or systemic administration or topical application.
Abstract: In a process for debittering bitter lupin seed the lupin seed is firstly very finely milled, more specially in a ball mill, and it is then extracted while cold and in counter current with solutions of lupin seed extract with different concentrations in steps, the solvent used being water. The filter cake produced on extraction is dried. After being increased in concentration, the solutions of lupin seed extract are stored and possibly further concentrated. The apparatus for use in the process has in addition to the ball mill a flat bed extractor and a number of storage spaces placed in circuit with each other and with the extractor, such spaces being used to take up the solutions of lupin seed extract.
Abstract: The anginal medicated compound according to the present invention comprises the active principle 2,4,6,8-tetramethyl-2,4,6,8-tetraazobicyclo-/3,3,0/-octanedione-3,7 of the formula: ##STR1## in combination with a pharmaceutical carrier. The medicated compound according to the present invention is useful for the treatment of patients suffering from ischemic heart disease.
Type:
Grant
Filed:
December 6, 1984
Date of Patent:
February 18, 1986
Assignee:
Institut Organicheskoi Khimii Imeni N.D. Zelinskogo Akademii Nauk SSSR
Inventors:
Irina E. Zimakova, Dania A. Valimukhametova, Irina V. Zaikonnikova, Vladimir F. Bogoyavlensky, Natalya V. Kaverina, Roman A. Kamburg, Anatoly M. Karpov, Lenor I. Khmelnitsky, Oleg V. Lebedev, Lia V. Epishina, Lidia V. Lapshina, Ljudmila I. Suvorova, Nikolai V. Darinsky, Sergei S. Novikov, deceased
Abstract: A method is provided for treatment of drug dependent subjects comprising the step of orally administering to such subjects during the period of drug withdrawal an herbal composition comprising Radix angelica sinensis, Herba pogostemi, Cyperus rotundus and Squama manitis pendactilae.