Abstract: A composition effective against the symptoms of venom, such as convulsions and throat blockage, suffered by a victim of a venomous creature, which composition comprises an ethyl alcohol infusion of previously dried herbs and iron filings, said alcohol infusion being a supernatant decanted from an infusion of from 28 to 31 liters of an ethyl alcohol and water solution containing at least 55% ethyl alcohol; from 130 to 300 grams of red cinchona; from 130 to 300 grams of curcuma root; from 60 to 100 grams of aloe; from 80 to 200 grams of saffron; from 80 to 200 grams of white agaric; from 80 to 200 grams of nutmeg; from 250 to 400 grams manna; from 150 to 330 grams of gencian; from 70 to 170 grams of orange blossom; from 80 to 200 grams of rhubarb; from 450 to 650 grams of cinnamon; and from 2,800 to 3,500 grams of iron filings.
Abstract: Sterile, glycerol free lipid emulsion suitable for parenteral administration and including alanine in an amount sufficient to provide pharmaceutically acceptable osmolality.
Abstract: Disclosed is a process for the preparation of a substance having a hypotensive component, which comprises mixing and extracting an oil-squeezed component from a soybean oil-preparing step with water, an aqueous solution of an acid, an aqueous solution of a salt or an aqueous solution of an acid and a salt, subjecting the extract to centrifugal separation, separating a hypotensive component from the aqueous phase, and, if necessary, drying the separated hypotensive component. This substance is valuable as a medicine or in the field of health-promoting foods.
Abstract: The invention concerns a composition, i.e., a multifunctional medically active agent for rational therapy of malignant (cancerous) diseases based on cause-and-effect relationship. The new composition according to the invention contains dimethylsulfoxide, DMSO, or sulfolan, preferably DMSO, in combination with a therapeutically effective amount of at least one cytostatic agent. The invention also concerns a method for treatment of malignant (cancerous) conditions in man comprising local or systemic administration thereto of an effective dosage of the composition according to the invention.The invention surprisingly provides a composition, as well as a method of treatment, allowing rational specific or selective carcinostatic-carcinocidic therapy. This therapy-form aims at the intracytoplasmic 3-dimensional cytoskeleton (differentiation organelle) that is specifically changed in the malignant cells, as well as at the targets responsible for karyokinesis and cytokinesis.
Abstract: An immunoactivator comprising an effective amount of a thiazolobenzoxazine derivative of the formula, or its salt ##STR1## wherein R.sup.1 represents a hydrogen atom, carboxyl group or lower alkoxycarbonyl group, R.sup.2 represents a substituted or unsubstituted phenyl group, lower alkyl group or furyl group, and R.sup.3 represents a hydrogen atom or lower alkoxy group.
Abstract: An emulsifier adapted for use in a nutritive oil-in-water emulsion suitable for parenteral administration is produced by extracting vegetable lecithin with alkyl alcohols having from 1 to 3 carbon atoms, or mixtures thereof, followed by fractional precipitation at specific temperatures and concentrations effective to cause the removal of toxic materials. The alcohol soluble phospholipid fraction produced by the process contains an increased level of phosphatidyl choline and reduced levels of phosphatidyl ethanolamine, inositol phospholipids, phosphatidic acid and glycolipids.
Abstract: A composition useful for the treatment of cancer comprises a colloidal or semi-colloidal suspension of DNA-repressor proteins derived from a finely divided mammal nerve tissue, particularly brain tissue.A method of treating cancer comprises administering to the patient a suitable daily dosage of the above composition, accompanied by the administration of suitable doses of immuno globulin (gamma-globulin), during a period of from 45 to 60 days.
Abstract: A composition for overcoming snoring as well as a process for its use is disclosed. The composition according to the invention contains a surface active substance, a preserving agent and/or a substance acting bactericidally or fungicidally on the mucous membranes and optionally a substance for softening the mucous membranes in physiological common salt solution as well as optionally further additives which are compatible with the mucous membranes.
Abstract: Continuous extraction of particulate solid material, particularly vegetable or animal raw material, with a highly compressed gas as a solvent includes forming a suspension by mixing a solid material with a liquefied gas in a suspension container under pressure which is lower than an extraction pressure, compressing the suspension to an extraction pressure greater than 10 bar and bringing to an extraction temperature, supplying the suspension into an extraction container which is supplied with fresh solvent in a counterstream to the solid material and from which an extract rich solution is withdrawn and thereafter the extracted solid material suspended in the liquefied gas is withdrawn from the extraction container, and continuously separating the withdrawn extract-poor solid material from the gas and discharging the same.
Type:
Grant
Filed:
August 2, 1983
Date of Patent:
November 19, 1985
Assignee:
Extraktionstechnik Gesellschaft Fur Anlagenbau mbH
Abstract: Plant material (for example, milled hop pellets) is placed in a pressure vessel and carbon dioxide is passed through the vessel in order to extract essential oil and resin components. Said passage is stopped after a predetermined period of time and inert gas(es) is/are used to displace said carbon dioxide and the extract(s) from said vessel to another location.If liquid carbon dioxide is used, it is displaced to an evaporator in which the extract is deposited, carbon dioxide being gasified. If supercritical carbon dioxide is used, it is displaced to a separator.Alternatively, the plant material may be steeped in liquid carbon dioxide which, after the steeping period, is displaced as aforesaid.The gases (carbon dioxide and inert) may be vented to atmosphere or recovered for re-use.Extraction using liquid carbon dioxide is isobaric whereas using supercritical carbon dioxide, the pressure in the pressure vessel is higher than in the separator.
Abstract: A novel combination pharmaceutical composition is described, together with a method for making the same, wherein the pharmaceutcially active ingredients are separately milled and then formed into separate granules, and only thereafter blended together to form the combination composition. The method for achieving this novel combination composition is also described. In particular, a novel combination composition of triamterene and hydrochlorothiazide having improved bioavialability and novel effectiveness to prevent or eliminate hypokalemic side effects is also described.
Abstract: A stable liquid formulation of the pesticide bendiocarb, especially for ultra low volume application, comprises the bendiocarb suspended in a chemically inert oil of low volatility and of low solubility for bendiocarb.
Abstract: A method for the treatment of diabetes is disclosed wherein the blood sugar of a patient in need of such treatment is lowered or reduced when an effective amount of an energizer composition containing basic food molecules and substances such as animal and plant proteins, carbohydrates, minerals, vitamins and thyroglobulin, is administered to the patient.
Abstract: The invention relates to cosmetic agents which contain, besides the usual basic cosmetic substances, natural yeast cell contents. The yeast cell contents are obtained by mechanically breaking open the yeast cell walls and by separating off the cell walls and any cell membranes, employing protective conditions. The invention relates also to extracts of yeast cell contents which contain an enriched fraction of yeast cell nuclei and which, when used in cosmetic agents, have an especially good skin-care effect. The native yeast cell contents comprise the cell contents without the cell walls, or the cell contents without cell walls and without nuclear membranes.
Abstract: The invention relates to a method of treating herpes zoster in a patient having herpes zoster wherein an effective amount of capsaicin is topically applied to the area affected with herpes zoster for a time sufficient to relieve the symptoms thereof.
Abstract: A stable composition containing cell wall skeleton (CWS) and trehalose dimycolates (TDM) which may be effectively reconstituted after lyophilization. The composition is useful in the treatment of various cancerous tumors in animals without side effects. Also disclosed is a method of producing the composition and a method of treating cancerous tumors in animals using said composition.
Type:
Grant
Filed:
March 19, 1984
Date of Patent:
May 28, 1985
Assignee:
Ribi ImmunoChem Research, Inc.
Inventors:
Edgar E. Ribi, John L. Cantrell, Steven M. Schwartzman
Abstract: A method of isolating material which inhibits virus replication in plants comprising isolating protoplasts from a local lesion-responding tobacco plant having an N gene, preferably a Samsun NN tobacco plant, inoculating the protoplasts with Tobacco Mosaic Virus, and either removing the protoplasts after a predetermined amount of time and isolating the desired material from the protoplast incubation medium, or removing the virus after a predetermined amount of time and isolating the desired material from the preparation.Also provided is a method of isolating material which inhibits virus replication in plants comprising isolating tissue from a "green island" area of a tobacco plant which responds systemically to Cucumber Mosaic Virus, preferably a Samsun NN, a Xanthi-nc or Samsun plant, homogenizing the tissue and isolating the desired material from the homogenate, as well as a method of immunizing plants against virus replication comprising applying thereto the material isolated as above.
Type:
Grant
Filed:
July 15, 1982
Date of Patent:
May 28, 1985
Assignee:
State of Israel, Ministry of Agriculture
Abstract: A process for preparing mangiferin from plants of the genus of Hedysarum (Hedysarum alpinum L., Hedysarum flavescens Rgl. et Schmalh) comprising extraction of xanthone glycosides from the aerial portion of the plants by means of a mixture acetone-water at a volume ratio of the mixture components of 1:0.5-2 respectively; the resulting extract is evaporated, the evaporated extract is filtered. To the filtered evaporated extract sulphuric acid is added to a pH of from 2 to 4, heated at reflux and filtered. The thus-prepared extract is treated with a non-polar organic solvent with the formation of two layers, wherefrom the upper aqueous layer contains xanthone glycosides. This upper layer is treated with butanol with the formation of two layers, wherefrom the upper layer comprises a solution of xanthone glycosides in butanol. This upper butanolic layer is evaporated. The precipitated mangiferin is separated and recrystallized.
Type:
Grant
Filed:
May 16, 1983
Date of Patent:
May 21, 1985
Inventors:
Svetlana V. Rusakova, Vladimir I. Glyzin, Stepan I. Kocherga, Alla A. Ananieva, Larisa F. Libizova