Abstract: Syringe assemblies comprising a disinfecting reservoir collar to ensure an adherence to aseptic techniques for use in flush procedures for vascular access devices (VAD's) are described. Also described are methods of disinfecting the vascular access devices.

Abstract: Refill and dosage management devices and associated systems and methods for use with computerized oral prescription administration (COPA) devices are provided. In one embodiment, an apparatus includes a housing having a structure sized and shaped to receive at least a portion of a mouthpiece of an intended user; and a dispensing unit coupled to the housing, the dispensing unit configured to dispense a substance into a reservoir of the mouthpiece. In another embodiment, a method includes receiving, by a docking station, at least a portion of a mouthpiece of an intended user; and dispensing, by a dispensing unit coupled to the docking station, a substance into a reservoir of the mouthpiece.

Abstract: The present disclosure relates to a safety mechanism (5) for a push-off cap of a medicament delivery device. The safety mechanism (5) includes a cap (9) and an actuator assembly (11). The cap (9) has a through-opening (9b) and is configured to be mounted to the proximal end of a medicament delivery device. The actuator assembly (11) is configured to be received by the cap (9), and extend proximally from the cap (9). The actuator assembly (11) is linearly displaceable relative to the cap (9), from a first position in which the actuator assembly (11), to a second position in which the actuator assembly (11) is displaced in the distal direction and received further by the cap relative to the first position. The actuator assembly (11) includes a guide structure configured to guide linear displacement of the actuator assembly (11) relative to the cap (9), a proximal top member (11c) and a lock structure (11d).

Abstract: A method for power injection of fluids through an access port includes implanting the access port in a patient, palpating the access port, imaging the access port, and introducing contrast media into the patient through the access port at a rate in a range from about two milliliters per second to about five milliliters per second. The access port may include a housing, a first septum, a second septum, and a radiographic indicator. The first septum and the second septum may respectively cover a first reservoir and a second reservoir of the access port. The first septum may include a first sub-pattern of protrusions and the second septum may include a second sub-pattern of protrusions. The radiographic indicator may include a first portion including information pertaining to the first sub-pattern, and a second portion including information pertaining to the second sub-pattern. The imaging identifies the radiographic indicator.

Abstract: A trocar assembly includes a seal assembly that maintains insufflation pressure when sized seal cartridges are removed and replaced. The trocar assembly includes a housing that defines a working chamber, and a cannula distally extends from the housing and defines a lumen that communicates with the working chamber. The seal cartridge is arranged within the working chamber, and may include one or both of a proximal seal assembly and a distal seal assembly arranged distally from the proximal seal assembly, and may further include a bushing extending distally from a distal end of the seal cartridge and into the lumen. A tertiary seal may also be positioned within the working chamber distal to the seal cartridge, such that the bushing extends through the tertiary seal when the seal cartridge is received within the working chamber.

Abstract: A flexible guide tube having a deflectable distal end is disclosed with at least first and second tensioning lines coupled to a deflectable distal end of the flexible guide tube. The first tensioning line is configured to deflect the distal end of the flexible guide tube in a first direction and the second tensioning line is configured to deflect the distal end of the flexible guide tube in a second direction that is opposite the first direction. A handle is coupled to flexible tube, the handle having a medial portion with a longitudinal axis substantially parallel with at least a portion of the flexible guide tube, a first actuator disposed proximal the medial section, and a second actuator disposed distal the medial section.

Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.

Abstract: A balloon catheter assembly is provided with an outer catheter, an inner catheter, an outer adapter and a balloon, and is configured such that the balloon resides entirely within a predetermined volume having an outer diameter substantially equal to or less than the outside diameter of the distal end of the outer catheter when the balloon is in a deflated configuration. Methods of using and steering the catheter assemblies are also provided.

Abstract: A thermic infusion system includes a thermal tubing system and a control system. The thermal tubing system has a tubal body with at least one tubal segment. The tubal segment includes a thermal element that may receive energy, such as electrical energy, to increase temperature within the tubal body. The control system may regulate the amount of energy received by the tubal segment using one or more sensors positioned within the tubal body.

Abstract: Ratchet-based drive systems for more reliable and safer drug delivery are provided. The ratchet-based drive systems restrict angular movement and/or linear movement of components that cause a plunger to expel a liquid drug from a drug container. Movement of the components can be restricted to correspond to a predetermined or desired portion of the liquid drug. In the case that control of the drive system is lost or fails, the maximum amount of drug that could be delivered is limited to a known amount, thereby reducing the likelihood of an overdose.

Abstract: A balloon catheter assembly is provided with an outer catheter, an inner catheter, an outer adapter and a balloon, and is configured such that the balloon resides entirely within a predetermined volume having an outer diameter substantially equal to or less than the outside diameter of the distal end of the outer catheter when the balloon is in a deflated configuration. Methods of using and steering the catheter assemblies are also provided.

Abstract: A reloadable auto injector has a needle insertion driver to be re-activated upon reloading. A syringe is movably positioned in a housing between a first position and a second position. A plunger rod is locked to a plunger rod tube by a deflectable locking member. A syringe driver applies a force to the syringe to move the syringe together with plunger rod tube, plunger rod and plunger rod driver from the first position to the second position. In the second position, the locking member is unlocked and releases the plunger rod to thereby activate the plunger rod driver to advance the plunger rod in the syringe for delivering of medicament. A reload handle is connected to the syringe assembly so that user operation of the reload handle retracts the syringe to the first position and simultaneously reloads the syringe driver for delivering a further dose of medicament.

Abstract: A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.

Abstract: A needle cover assembly can be used with a medicament delivery device, wherein said needle cover assembly is disposable and comprises a retainer element connectable to a medicament container holder; a hub having a longitudinal axis and comprising a double pointed injection needle with a proximal needle end and a distal needle end, wherein the proximal needle end projects a distance from the hub along the longitudinal axis, and a shield covering at least the proximal needle end and a portion of the hub. Said shield comprises a detachable element, that the shield is attached to the hub when said detachable element is attached to the shield, corresponding to an untampered state, and that the shield is released and is telescopically movable in relation to the hub along the longitudinal axis when said detachable element is detached from the shield corresponding to an activated state.

Abstract: A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The sealing member includes microholes which vent fluid above a certain pressure threshold. A headset may connect the earplug to a second earplug. The method involves using the system on a human or animal subject.

Abstract: A needle injection array can comprise a plurality of needles that are fluidly interconnected via a fluid manifold. The fluid manifold can be configured to direct fluid from a syringe to arrive at tips of the needles approximately simultaneously. The fluid manifold also be configured to provide approximately equal dosage or fluid volume through each of the needles to an injection site.

Abstract: A surgical system comprises a pressurized irrigation fluid source; an irrigation line fluidly coupled to the pressurized irrigation fluid source; a hand piece fluidly coupled to the irrigation line; an irrigation pressure sensor located at or along the pressurized irrigation fluid source or irrigation line; and a controller for controlling the pressurized irrigation fluid source. The controller controls the pressurized irrigation fluid source based on a reading from the irrigation pressure sensor and an estimated flow value modified by a compensation factor.

Abstract: A fluid injecting system (100) comprising an injector (A) having an injector body (10), a plunger shaft (30), a plunger assembly (20) having an inner plunger barrel (21) slidable within an outer plunger barrel (22), a fluid-cartridge (B) having a fluid (53) and a hypodermic needle (72) for injecting the fluid (53) at an injectable site. The fluid-cartridge (B) is configured to releasably engage with the injector (A). A vacuum (V) is created between the outer plunger barrel (22) and the inner plunger barrel (21) upon formation of a united plunger barrel (40). Also, forward movement of the united plunger barrel (40) transfers the fluid (53) from the fluid-cartridge (B) into the injectable site. The hypodermic needle (72) retracts within empty fluid-cartridge (B) due to release of the vacuum (V) and the injector (A) is disengaged from the fluid-cartridge (B) for reuse. Further, a fluid injecting method (300) is provided.

Abstract: A method and/or system may be provided for determining a suggested change in a recommended therapy for a patient based, at least in part, on sensor measurements, and generating an alert to an attendant in a hospital environment upon detection of the suggested change. A method and/or system may also be provided to automatically determine a maximum interval to alert an attendant following receipt of a measurement at an operator interface. A method and/or system may also be provided to blood-glucose sensor calibration.

Abstract: An auto injector having sequential control of needle insertion and dose injection is disclosed. A syringe with a needle is movably positioned in a housing between a first position in which the needle is accommodated inside the housing and a second position in which the needle protrudes outside the housing. A plunger rod tube has at least one locking member configured to normally lock a plunger rod to the plunger rod tube. A syringe driver applies a force to the syringe to move the syringe together with plunger rod tube, plunger rod and plunger rod driver from the first position to the second position. In the second position, the locking member is unlocked and releases the plunger rod to thereby activate the plunger rod driver to advance the plunger rod in the syringe for delivering of at least one dose of medicament.