Abstract: Liquid/liquid extraction process for copper from an aqueous sulphuric acid solution acting on the concentrated mineral or semi-finished product to be treated.The extraction is carried out in an organic solvent containing in solution an extraction agent derived from 2-phenyl-4-acyl-(3H)-pyrazol-3-ones, with the phenyl group subsitituted or unsubstituted.Application to the upgrading of minerals.

Abstract: Disclosed herein are alpha adrenergic and nasal decongestant compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, each being the same or different, are halogens, and the pharmaceutically acceptable salts thereof.

Abstract: The present invention relates to imidazolines of general formula (I) ##STR1## and the addition salts formed therefrom with the pharmaceutically acceptable mineral or organic acids, possibly having their own specific pharmacological properties.The invention further relates to the preparation of these products, to their use as new medicines and to the medicinal compositions containing them.

Abstract: A compound of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom, a lower alkyl group or a halo(lower)alkyl group, R.sub.2 and R.sub.3 are, the same or different, each a hydrogen atom, a halogen atom, a nitro group, a cyano group or an optionally substituted lower alkyl, lower alkenyl, lower alkynyl, cyclo(lower)alkyl, lower alkoxy, lower alkenyloxy, lower alkynyloxy, cyclo(lower)alkoxy, lower alkylthio, lower alkenylthio, lower alkynylthio, cyclo(lower)alkylthio, di(lower)alkylamino, lower alkylsulfonyl or lower alkylsulfinyl group, or R.sub.2 and R.sub.3 are combined together to form an optionally substituted 5- or 6-membered, saturated or unsaturated ring optionally having not more than two oxygen or sulfur atoms in the ring, R.sub.4 is a halogen atom or a lower alkyl group, R.sub.

Abstract: Novel thioketene derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen atom, an alkyl group, a lower alkenyl group, a phenyl group or a group of the formula: --B--Y;Y is a nitrogen-containing monocyclic heterocyclic group or a substituted or unsubstituted phenyl group;B is a straight or branched lower alkylene group;R.sup.2 and R.sup.3 are both a lower alkyl group or are combined together to form a group of the formula: --CH.sub.2 CH.sub.2 -- or --CH.dbd.CH--;R.sup.4 is hydrogen atom, a lower alkyl group or a (lower alkoxy)carbonyl group;A is a group of the formula: --(CH.sub.2).sub.n -- or --CH(COOR.sup.5)--;n is an integer of 0, 1 or 2 andR.sup.5 is a lower alkyl group,are disclosed. The compound (I) is useful as an agent for treating and protecting various liver diseases.

Abstract: A process is provided for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine, reacting acetone with ammonia in the presence of a catalytically effective amount of an organic carboxylic acid halide.

Abstract: This invention relates to N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamide compounds which are useful as pesticides, compositions containing those compounds, methods of controlling pests and processes for preparing these compounds.

Abstract: This invention provides certain imidazole derivatives, their pharmaceutical formulations, and their use in a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals.

Abstract: A process is provided for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine, reacting acetone with 2,2,4,4,6-pentamethyl-2,3,4,5,-tetrahydropyrimidine in the presence of a catalytically effective amount of an organic carboxylic acid halide.

Abstract: An acetanilide derivative of the following formula (I) and a herbicide containing one or more of the acetanilide derivative as the active ingredient are described. ##STR1## In the formula, R.sup.1 is a lower alkyl group; R.sup.2 is a fluorine-substituted lower alkyl group; A is ##STR2## B is an optionally substituted pyrazolyl group, an optionally substituted alkoxy group or a hydrogen atom.The acetanilide derivative and the herbicide have a selective weed killing activity to gramiveous weeds.

Abstract: Combating diseases of the respiratory tract, inflammations, rheumatism, thromboembolic diseases, ischaemias and infarcts, cardiac arrhythmias and arteriosclerosis with pyrazolediones of the formula ##STR1## wherein R represents an aryl or heteroaryl radical which has 6 to 12 C atoms and optionally contains 1 to 3 identical or different substituents from the group comprising halogen, trifluoromethyl, alkyl, alkenyl, alkoxy, alkylamino, cyano, trifluoromethoxy, nitro, hydroxyl, SO.sub.n -alkyl (n=0 to 2) or SO.sub.n -trifluoromethyl ) n=0 to 2), alkyl, alkenyl and alkoxy each having up to 4 C atoms,R.sup.1 represents hydrogen or a hydrocarbon radical which has 1 to 18 C atoms and optionally contains a hydroxyl, ether, ester or carboxyl group and optionally contains 1 to 3 halogen atoms, and X represents one of the groups --CH.sub.2 --CH.sub.2 --CH.sub.2 --, --O--CH.sub.2 --CH.sub.2 --, --S--CH.sub.2 --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --CH.sub.

Abstract: 5-Amino or substituted amino imidazoles are disclosed as having anticoccidial activity. The compounds are useful for controlling cecal and or intestinal coccidiosis when administered in minor quantitites to animals, in particular to poultry, usually in admixture with animal sustenance.

Abstract: This invention provides certain azole derivatives and their pharmaceutical formulations. Also provided is a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering the azole derivatives.

Abstract: Novel synthetic routes to (3a.alpha.,6a.alpha.)-1,3-dibenzyl hexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one 5,5-dioxide, a known intermediate in the synthesis of biotin are provided.A novel synthetic route from this intermediate to biotin is also disclosed.

Abstract: The invention is related to imidazol-2-yl mercapto alkanoic acids having the formula I ##STR1## process for the treatment of humans suffering from inflammatory diseases or diseases in relation with the lipid metabolism.

Abstract: The invention concerns a process for producing cyclic ureas of the general formula (II): ##STR1## in which R is selected from the group comprising hydrogen atom and C.sub.1 -C.sub.4 alkyl radicals through condensation in aqueous medium at a pH of between 4 and 7 and at a temperature of between 40.degree. and 60.degree. C. of glyoxal with or without excess of a urea having the general formula (I):RNH--CO--NHR (I)in which R has the same meaning as above, said process being conducted in the presence of a catalytic amount of orthophosphoric acid.

Abstract: 1-Substituted-spiro[chroman-4,4'-imidazolidine]-2',5'-dione compounds are useful for treating arrhythmia.

Abstract: The present invention relates to a 1,8-naphthyridine derivative of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and each hydrogen or lower alkyl having 1 to 5 carbon atoms; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.

Abstract: Pyrazole derivatives, selective herbicidal compositions containing said derivatives and the use of said derivatives are provided. The pyrazole derivatives having selective herbicidal activity are represented by the formula I: ##STR1## wherein, X denotes a halogen, nitro or methanesulfonyl,Y denotes hydrogen, a lower alkyl or a halogen,Z denotes a halogen or methanesulfonyl, andR denotes hydrogen; an organic acid residue; a lower alkynyl; a lower alkyl or a lower alkenyl which may be substituted by a halogen, hydroxy, cyano or an alkoxycarbonyl; or a benzyl which may be substituted by a halogen, nitro or a lower alkyl.

Abstract: Substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and .beta.-adrenergic blocking activity.