Patents Examined by Kurt G. Briscoe
  • Patent number: 4767779
    Abstract: Pyrazolines of the following formula are insecticides: ##STR1## wherein R.sub.A, R.sub.B and R.sub.C are aromatic groups; R.sub.N is hydrogen or lower alkyl; and W is oxygen or sulfur.
    Type: Grant
    Filed: April 9, 1986
    Date of Patent: August 30, 1988
    Assignee: FMC Corporation
    Inventor: Angelina J. Duggan
  • Patent number: 4766132
    Abstract: Compounds of formula: ##STR1## and stereoisomers thereof, wherein R.sup.1 is unsubstituted or substituted aryl or heteroaryl; R.sup.2 is H, alkyl, alkenyl or alkynyl; X is O, NH, or S; R.sup.3 being alkyl, alkenyl, alkynyl or COR.sup.4 where R.sup.4 has an R.sup.3 value, when X is O; R.sup.3 being --CO-- alkyl when X is NH; and R.sup.3 being alkyl, alkenyl or CSNR.sup.5 R.sup.6 where R.sup.5 and R.sup.6, which may be the same or different, are H, alkyl, alkenyl or, together with the adjacent N atom, constitute a ring, when X is S; or XR.sup.3 together represent --CN; and salts and metal complexes thereof, have fungicidal and plant growth regulating activity.
    Type: Grant
    Filed: January 29, 1986
    Date of Patent: August 23, 1988
    Assignee: Imperial Chemical Industries PLC
    Inventor: Ian T. Kay
  • Patent number: 4764612
    Abstract: The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which the variables are as defined in the specification.The compounds of formula (I) show pharmacological activity as selective histamine H.sub.2 -antagonists.Also disclosed are intermediates in the preparation of the compounds of the formula (I).
    Type: Grant
    Filed: February 6, 1986
    Date of Patent: August 16, 1988
    Assignee: Glaxo Group Limited
    Inventors: John W. Clitherow, John Bradshaw, John W. M. Mackinnon, Barry J. Price, Michael Martin-Smith, Duncan B. Judd
  • Patent number: 4764527
    Abstract: 1-Hydroxypyrazoles of the formula ##STR1## where R.sup.1, R.sup.2 and R.sup.3 independently of one another are each hydrogen or halogen, and microbicides containing these compounds.
    Type: Grant
    Filed: May 29, 1987
    Date of Patent: August 16, 1988
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Wagner, Norbert Rieber, Ernst-Heinrich Pommer
  • Patent number: 4764202
    Abstract: 5-Dichloracetamido-4-nitro-1-aryl-pyrazoles of the formula ##STR1## in which R.sup.1 represents hydrogen, fluorine, chlorine or bromine,R.sup.2 represents hydrogen, fluorine or chlorine,R.sup.3 represents halogen, halogenoalkyl, halogenoalkoxy, halogenoalkylthio or halogenoalkylsulphonyl,R.sup.4 represents hydrogen, fluorine, or chlorine, andR.sup.5 represents fluorine, chlorine or bromine, but in the case in which R.sup.1 and R.sup.5 simultaneously represent chlorine and in addition R.sup.2 and R.sup.4 simultaneously represent hydrogen, R.sup.3 does not represent chlorine or trifluoromethyl,exhibit herbicidal and plant growth-regulating properties. Novel intermediates therefor are also shown.
    Type: Grant
    Filed: November 24, 1986
    Date of Patent: August 16, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Gehring, Otto Schallner, Jorg Stetter, Albrecht Marhold, Hans-Joachim Santel, Robert R. Schmidt, Klaus Lurssen
  • Patent number: 4761484
    Abstract: Liquid/liquid extraction process for copper from an aqueous sulphuric acid solution acting on the concentrated mineral or semi-finished product to be treated.The extraction is carried out in an organic solvent containing in solution an extraction agent derived from 2-phenyl-4-acyl-(3H)-pyrazol-3-ones, with the phenyl group substituted or unsubstituted.Application to the upgrading of minerals.
    Type: Grant
    Filed: December 10, 1986
    Date of Patent: August 2, 1988
    Assignee: Societe Nationale des Poudres et Explosifs
    Inventors: Jean-Claude Gautier, Serge Lecolier, Claude Soriaux, Sammy Chlvalier
  • Patent number: 4758673
    Abstract: 1-Aryl-pyrazoles of the general formula ##STR1## in which Hal represents halogen,R.sup.1 and R.sup.3 independently of one another represent cyano, nitro, halogen, alkyl, alkoxy, alkoxycarbonyl, halogenoalkyl, halogenoalkoxy or a radical --S(O).sub.n --R.sup.6 andR.sup.2, R.sup.4 and R.sup.5 independently of one another and independently of R.sup.1 and R.sup.3 represent the same radicals as R.sup.1 and R.sup.3, and additionally represent hydrogen,and whereinR.sup.6 represents alkyl, halogenoalkyl, amino, alkylamino or dialkylamino and n-represents the number 0, 1 or 2 are disclosed.These compounds can be nitrated to form herbicially effective 1-aryl-4-nitropyrazoles.
    Type: Grant
    Filed: February 19, 1987
    Date of Patent: July 19, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Gehring, Otto Schallner, Jorg Stetter, Hans-Joachim Santel, Robert R. Schmidt
  • Patent number: 4757148
    Abstract: A compound of formula I ##STR1## in which formula: R.sub.1 represents hydrogen or an alkyl group;R.sub.2 -R.sub.5 represent hydrogen, alkyl aryl, aralkyl or alkaryl group; andn is 1 or 2.
    Type: Grant
    Filed: November 10, 1986
    Date of Patent: July 12, 1988
    Assignee: National Research Development Corporation
    Inventors: Israr Ahmed, Gerald E. Adams, Ian J. Stratford, David Gibson
  • Patent number: 4754032
    Abstract: Compounds of formula I ##STR1## can be used as optical brighteners.
    Type: Grant
    Filed: February 26, 1986
    Date of Patent: June 28, 1988
    Assignee: Sandoz Ltd.
    Inventors: David L. Connell, John M. Farrar, Jurg Heller, Hans-Rudolf Schmid
  • Patent number: 4752326
    Abstract: As compounds is provided a pyrazole derivative of the formula ##STR1## wherein R.sub.1a, R.sub.1b and R.sub.1c are each a hydrogen atom, a halogen atom, a nitro group, an amino group, a (lower) alkyl group, a halo-(lower)alkyl group, a(lower)alkenyl group, a (lower)alkynyl group, a (lower)alkylcarbonylamino group, a (lower)alkoxycarbonylamino group, a mono-(lower) alkylaminocarbonylamino group or a di-(lower)alkylaminocarbonylamino group;R.sub.2 is a hydrogen atom, a (lower)alkyl group, a (lower)alkenyl group, a (lower)alkynyl group, a (lower) alkoxy(lower)alkyl group, a (lower)alkylthio(lower)alkyl group, a (lower)alkylcarbonyl(lowr)alkyl group, a (lower) alkoxycarbonyl(lower)alkyl group, a (lower)alkylthiocarbonyl(lower)alkyl group, a cyano(lower)alkyl group, a (lower)alkylsulfonyl group, phenylsulfonyl group, a halogen-substituted phenylsulfonyl group or a (lower) alkyl-substituted phenylsulfonyl group, andX and Y are the same or different and each are a halogen atom.
    Type: Grant
    Filed: May 8, 1986
    Date of Patent: June 21, 1988
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Hiroshi Ohyama, Toshiharu Ono, Takuro Shimozono, Teruhiko Terakawa
  • Patent number: 4752321
    Abstract: A compound of the general formula (I): ##STR1## wherein R is C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkynyl, both optionally substituted by lower alkyl, halogen or trialkylsilyl; E is CN or CSHN.sub.2 ; and Y is C.sub.1 -C.sub.4 alkoxy, C.sub.3 -C.sub.4 alkenyloxy, C.sub.3 -C.sub.4 alkynyloxy, 1-pyrazolyl or 2-furyl. The compounds have fungicidal and plant growth regulating activity.
    Type: Grant
    Filed: November 18, 1986
    Date of Patent: June 21, 1988
    Assignee: Imperial Chemical Industries PLC
    Inventors: Stephen P. Heaney, Patrick J. Crowley, Laurence G. Reynolds
  • Patent number: 4752325
    Abstract: A compound of the formula: ##STR1## wherein R is a C.sub.2 -C.sub.3 alkyl group, a C.sub.3 -C.sub.4 alkenyl group or a C.sub.3 -C.sub.4 alkynyl group and X is a chlorine atom or a bromine atom, which is useful as a herbicide.
    Type: Grant
    Filed: February 5, 1985
    Date of Patent: June 21, 1988
    Assignee: Sumitomo Chemical Co., Ltd.
    Inventors: Toru Haga, Eiki Nagano, Ryo Sato, Ryo Yoshida
  • Patent number: 4751229
    Abstract: A method of treating fungal infections in mammals employing 1,3,5-trisubstituted-4- (4-hydroxy-2-oxo-pyran-6-yl)pyrazoles is disclosed.
    Type: Grant
    Filed: July 9, 1987
    Date of Patent: June 14, 1988
    Assignee: Warner-Lambert Company
    Inventors: Carl L. Heifetz, Milton L. Hoefle, Bruce D. Roth, Drago R. Sliskovic, Michael W. Wilson
  • Patent number: 4747867
    Abstract: Herbicidally active 1-aryl-4-cyano-5-halogenopyrazoles of the formula ##STR1## in which R is hydrogen or alkyl,Hal is halogen, andAr is substituted phenyl or represents polysubstituted pyridyl.Intermediates of the formulas ##STR2## are also disclosed.
    Type: Grant
    Filed: May 22, 1986
    Date of Patent: May 31, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Gehring, Uta Jensen-Korte, Otto Schallner, Jorg Stetter, Hans-Joachim Santel, Robert R. Schmidt
  • Patent number: 4748245
    Abstract: A process for the preparation of phenylthiopyrimidines which comprises: (a) reacting a thiopyrimidine; with sulfuryl chloride in the presence of a suitable solvent to form the sulfenyl chloride of said thiopyrimidine; (b) reacting said sulfenyl chloride of said thiopyrimidine with a phenol or substituted phenol, optionally in the presence of a Friedal-Crafts catalyst, to form a thiopyrimidinyl phenol; and (c) reacting said thiopyrimidinylphenol formed in step (b) with a base and an alkylating agent to form the end product.
    Type: Grant
    Filed: March 20, 1986
    Date of Patent: May 31, 1988
    Assignee: Stauffer Chemical Company
    Inventor: Donald R. James
  • Patent number: 4746354
    Abstract: Herbicidally and insecticidally active 4-nitro-1-phenylpyrazoles of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently is hydrogen, alkyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, alkylthioalkyl or halogenoalkyl,R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 each independently is hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkoxycarbonyl, or --(X).sub.n --R.sup.8,X is oxygen, sulphur, sulphinyl or sulphonyl,n is 0 or 1, andR.sup.8 is halogenoalkyl.
    Type: Grant
    Filed: March 4, 1986
    Date of Patent: May 24, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Gehring, Uta Jensen-Korte, Otto Schallner, Jorg Stetter, Hans-Joachim Santel, Robert R. Schmidt, Wolfgang Behrenz
  • Patent number: 4744815
    Abstract: Pyrazole derivatives of the formula I: ##STR1## wherein R represents a lower alkyl group or a lower alkenyl group atoms which may be substituted by halogen atom,X represents a halogen atom, a lower alkyl group, nitro group, cyano group, a lower alkylsulfonyl group or trifluoromethyl group,n is an integer of 2 to 4,Q represents hydrogen atom; an aralkyl group which may be substituted by halogen atom, nitro group, cyano group or a lower alkyl group; benzenesulfonyl group which may be substituted by a lower alkyl group or halogen atom; benzoyl group which may be substituted by a lower alkyl group or halogen atom; phenacyl group which may be substituted by a lower alkyl group or halogen atom; a lower alkyl group which may be substituted by halogen atom; a lower alkenyl group which may be substituted by halogen atom; or a lower alkynyl group,and a method for preparation of said derivatives, a selective herbicidal composition containing said derivatives as active ingredient,as well as a method for controlling weeds
    Type: Grant
    Filed: May 6, 1986
    Date of Patent: May 17, 1988
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Masatoshi Baba, Norio Tanaka, Takasi Ikai, Tsutomu Nawamaki
  • Patent number: 4743615
    Abstract: Fungicidally active substituted pyrazolin-5-ones of the formula ##STR1## in which R.sup.1 and R.sup.2 independently of one another each represents hydrogen, alkyl, alkenyl, alkinyl, cyanoalkyl, hydroxyalkyl, alkoxyalkyl, alkylthioalkyl, alkoxycarbonyl, hydroxycarbonylalkyl, alkoxycarbonylalkyl, aminocarbonylalkyl, alkylaminocarbonylalkyl or dialkylaminocarbonylalkyl, or represents in each case optionally substituted oxiranylalkyl, aralkyl, heterocyclyl or aryl, andR.sup.3 represents halogenoalkyl, halogenoalkenyl or halogenoalkinyl, or represents substituted cycloalkyl, or represents substituted cycloalkylalkyl.
    Type: Grant
    Filed: October 31, 1986
    Date of Patent: May 10, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Jelich, Wilhelm Brandes, Gerd Hanssler, Paul Reinecke
  • Patent number: 4743613
    Abstract: Compounds having the formula: ##STR1## which are ester prodrugs of potent dopamine-.beta.-hydroxylase inhibitors and thus are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmeceutical compositions including these compounds, and methods of using these compounds to inhibit dopamine-.beta.-hydroxylase activity in mammals.
    Type: Grant
    Filed: April 8, 1986
    Date of Patent: May 10, 1988
    Assignee: SmithKline Beckman Corporation
    Inventors: James S. Frazee, Carl Kaiser, Lawrence I. Kruse, Stephen T. Ross
  • Patent number: 4743612
    Abstract: Orally active prodrug derivatives of the cardiotonic agent 4-ethyl-1,3-dihydro-5-[4-(2-methyl-1H-imidazol-1-yl)benzoyl]-2H-imidazol-2 -one are disclosed. Pharmaceutical formulations containing such compounds are also provided.
    Type: Grant
    Filed: October 17, 1986
    Date of Patent: May 10, 1988
    Assignee: Berlex Laboratories, Inc.
    Inventors: Paul W. Erhardt, Alfred A. Hagedorn, III