Patents Examined by Kyle A Purdy
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Patent number: 12648900Abstract: The object of the present invention concerns a hair restructuring association comprising or alternatively consisting of: (a) a quaternary ammonium salt of formula (I) and (b) at least one sulpho-derivative of vegetable fatty acids, wherein R5, R6 are independently chosen between hydrogen and a radical R0, R0 consists of the following structure of formula (II), R1 is chosen from the group consisting of: hydrogen, methyl, isopropyl, sec-butyl, isobutyl, ethylenemethylthio, benzyl, para-hydroxybenzyl and 3-methylene-1H-indole, R2, R3, R4 are independently chosen from the group consisting of: methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl and tert-butyl, mX? is chosen from the group consisting of: formic acid, acetic acid, unsaturated monocarboxylic acids, adipic acid, aldaric acid, oxalic acid, phthalic acid, azelaic acid, sebacic acid, malonic acid, succinic acid, tartaric acid, glutaric acid, pimelic acid, maleic acid, malic acid, fumaric acid and suberic acid, isocitric acid, citric acid, faType: GrantFiled: April 12, 2022Date of Patent: June 9, 2026Assignee: Greengredients S.r.l.Inventor: Dottor Guido Bregaglio
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Patent number: 12649000Abstract: A method for translocating a cationic micro/nanoparticle across a mucus layer, the method including (a) contacting the mucus layer with at least one alginate oligomer, the alginate oligomer having at least 70% mannuronate residues, together with the cationic micro/nanoparticle; or (b)(i) contacting the cationic micro/nanoparticle with an alginate oligomer having at least 70% mannuronate residues thereby forming a micro/nanoparticle carrying the alginate oligomer, and (b)(ii) contacting the mucus layer with the micro/nanoparticle prepared in step (b)(i).Type: GrantFiled: March 19, 2019Date of Patent: June 9, 2026Assignee: AlgiPharma ASInventors: Aristides Tagalakis, Stephen Hart, Are Kristiansen, Arne Dessen, Philip D. Rye
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Patent number: 12648922Abstract: Described herein are pet food compositions for reducing circulating pro-inflammatory cytokines in companion animals. Methods of making and using the same are also described.Type: GrantFiled: November 2, 2018Date of Patent: June 9, 2026Assignee: Hill's Pet Nutrition, Inc.Inventors: Dennis Jewell, Kiran Panickar
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Patent number: 12636331Abstract: The present disclosure relates to a composition for preventing or treating lung cancer, comprising a compound isolated from a Cephalotaxus extract as an active ingredient. Isoharringtonine, which is the compound isolated from the Cephalotaxus extract according to the present disclosure, induces apoptosis and exhibits the effect of inhibiting the growth of non-small cell lung cancer cell lines, and thus can be useful in the prevention or treatment of lung cancer. In addition, the combined treatment of isoharringtonine and siNR4A1 enhances anticancer activity, and the combined treatment of isoharringtonine and cisplatin, which is a conventional anticancer drug, induces a high anticancer effect at a low concentration of cisplatin, thereby reducing side effects of anticancer treatment.Type: GrantFiled: October 5, 2021Date of Patent: May 26, 2026Assignees: NATIONAL CANCER CENTER, NATIONAL INSTITUTE FOR KOREAN MEDICINE DEVELOPMENTInventors: Kyung Sil Yoon, Yong Nyun Kim, Jae Gal Shim, Dong Hoon Shin, Hyo Jung Kim, Myoung Lae Cho, Soo Hyun Kim
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Patent number: 12636412Abstract: The invention described herein relates to a therapeutic, moisturizing coating composition for elastomeric articles which is applied directly onto the skin-contacting surface of the article as part of the manufacturing process. The coating composition is thermally stable and subsequently hydrates when contacted with a moisturized skin surface to convert into a liquid “lotion” form during wearing of the article. The coating composition provides therapeutic benefits to the wearer's skin as a result of wearing the article, such as improved skin moisturization, softness of feel, improved skin elasticity and firmness, and reduced redness and irritation. The invention is particularly useful in medical gloves, including examination and surgical gloves.Type: GrantFiled: January 24, 2020Date of Patent: May 26, 2026Assignee: ALLEGIANCE CORPORATIONInventors: Shiping Wang, Yun-Siung Tony Yeh, James Owens, Wei Cheong Wong
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Patent number: 12622888Abstract: Provided is a pharmaceutical composition and application thereof, specifically, said pharmaceutical composition comprises: salvianolic acid B as a first active ingredient; and ginsenoside Rg1 as a second active ingredient, and the weight ratio of the first active ingredient to the second active ingredient being 5:(1-4.5). The pharmaceutical composition has a better active-ingredient proportion than the prior art, has a better therapeutic efficacy in preventing and/or treating ischemic diseases, and ischemia-reperfusion tissue or organ damage, and can be used for treating ischemia and/or ischemia-reperfusion damage of different tissues and organs.Type: GrantFiled: August 28, 2020Date of Patent: May 12, 2026Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCESInventors: Baohong Jiang, Linlin Wang, Xiaoyu Wang, Yao Fu, Huimiao Bian, Rongrong Xing
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Patent number: 12617929Abstract: A solid material including a matrix, dispersed in which are microparticles of at least one antimicrobial agent for preventing, limiting and/or eliminating the contamination of the material and/or the contamination of a composition which is in contact with the material for at least a given time, and/or preventing, eliminating and/or slowing down the formation of biofilms on the surface of the material, wherein the antimicrobial agent is an oxide of at least one positively charged metal ion and the antimicrobial agent does not migrate out of the material. Also, the use of such material for manufacturing an article, to the process for manufacturing the article, and to the article obtained.Type: GrantFiled: June 22, 2023Date of Patent: May 5, 2026Assignee: PYLOTEInventor: Loic Marchin
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Patent number: 12604899Abstract: The present application provides powder metal ion disinfectant compositions, methods for preparing powder metal ion disinfectant compositions, and methods of disinfecting an article and/or maintaining the pathogenic sterility of the article using the solid powder metal ion disinfectant composition. These solid powder disinfectant compositions are light stable heat stable, non-toxic, and non-corrosive, achieve a greater than 99% kill rate of a variety of pathogens for up to 60 days on a variety of surfaces, and do not contain nanoparticles.Type: GrantFiled: August 15, 2022Date of Patent: April 21, 2026Assignee: Onyx Lotus, LLCInventors: Amyn Nanjee, Dana Nanjee, Gajanan Pawar, Varun Tahlan, Tom Johnson
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Patent number: 12599128Abstract: Compositions and methods for improving one or more agronomic traits of a plant are provided, which include the use of one or more fatty acids that kill or inhibit the growth of cells in the shoot apical meristem and optionally one or more surfactants. Use of the composition between vegetative growth stage 1 (V1) and vegetative growth stage 6 (V6) is described.Type: GrantFiled: January 5, 2024Date of Patent: April 14, 2026Assignee: The Board of Trustees of the University of IllinoisInventor: Ken N. Paige
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Patent number: 12590075Abstract: A refining method according to the present invention is a refining method for crystallizing a compound with at least one crystal form, including: setting, as a target wavelength, a specific infrared wavelength at which a specific crystal form precipitates from a solution of the compound dissolved in a solvent; and using an infrared radiation apparatus capable of emitting infrared radiation including the target wavelength to evaporate the solvent and precipitate the specific crystal form while irradiating the solution with infrared radiation including the target wavelength. The specific infrared wavelength is preferably set as the target wavelength based on an infrared absorption spectrum of the crystal form and the dissolution rate of the compound in the solvent.Type: GrantFiled: December 28, 2022Date of Patent: March 31, 2026Assignee: NGK INSULATORS, LTD.Inventors: Norimitsu Tohnai, Daiki Kato, Yoshio Kondo, Kazunari Yamada
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Patent number: 12575565Abstract: Disinfectant/sanitizer solutions contain aldehyde, surfactant, a quaternary ammonium compound, a main solvent and a co-solvent. Clear disinfectant/sanitizer solutions are made by adding the components of the solutions in a certain order and mixing them together. Concentrated disinfectant/sanitizer solutions can be diluted prior to being applied to a hard surface. Disinfectant/Sanitizer solutions are in the form of a liquid or spray. Liquid disinfectant/sanitizer solutions may be applied to a hard surface using a wipe impregnated or wetted with the solutions.Type: GrantFiled: July 16, 2021Date of Patent: March 17, 2026Assignee: Sterilex, LLCInventor: Nathan Richard Ortmann
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Patent number: 12568974Abstract: The present invention relates, in general terms, to a face mask. The present invention also relates, in general terms, to composite material, iron-iron oxide compositions and their methods of fabrication thereof. In particular, the iron-iron oxide composition comprises a cashew testa extract and iron particles and/or oxide core-shell particles. The iron-iron oxide composition can be used as an anti-microbial composition.Type: GrantFiled: April 7, 2021Date of Patent: March 10, 2026Assignee: N&E Innovations Pte. Ltd.Inventors: Didi Gan, Jie Lin Jaslyn Lee
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Patent number: 12570568Abstract: A glass includes from 42 mol % to 47 mol % P2O5, from 42 mol % to 48 mol % CuO, and from greater than 0 mol % to 15 mol % Fe2O3. The glass is an amorphous, single-phase glass. Methods of making a glass article include heating batch materials to a melting temperature from 900° C. to 1350° C. In aspects, methods include pouring the molten glass in an inert gaseous environment, and cooling the molten glass in the inter gaseous environment. In aspects, methods include cooling the molten glass to form the glass article and annealing the glass article without growing crystals in or on the glass article during the cooling or the annealing.Type: GrantFiled: September 13, 2022Date of Patent: March 10, 2026Assignee: CORNING INCORPORATEDInventors: Timothy Michael Gross, Alexandra Lai Ching Kao Andrews Mitchell
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Patent number: 12550901Abstract: Aqueous herbicide compositions containing a salt of glufosinate and a salt of a synthetic auxin herbicide are described. Such compositions exhibit good compatibility and reduced viscosity. Methods of reducing the viscosity of an aqueous herbicide composition are also disclosed.Type: GrantFiled: April 26, 2019Date of Patent: February 17, 2026Assignee: CORTEVA AGRISCIENCE LLCInventors: Fuquan Tu, Mei Li
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Patent number: 12545965Abstract: Provided herein are methods for assessing ageing process, lifespan, life expectancy, biological age and the rate of aging by determining pangenome gene alterations. Specifically, the methods comprising determination of the alteration of the gene composition in mammals and/or non-living genetic elements (NLGE) associated with mammals and at least one of the following: microbiota and/or NLGE associated with microbiota. The methods can be used for increasing lifespan and/or for inhibiting aging in mammals.Type: GrantFiled: July 3, 2019Date of Patent: February 10, 2026Inventors: Viktor Veniaminovich Tets, Georgy Viktorovich Tets
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Patent number: 12543744Abstract: Formulations of pesticides are disclosed, specifically pesticidal blends of essential oils and other ingredients, that have been found to enhance the activity of the active pesticidal ingredients. The formulations may be, for example, emulsions or dust formulations. For example, a composition for controlling a target pest is disclosed that comprises at least one active agent and a formulation agent, wherein: the active agent is capable of interacting with a receptor in the target pest; the active agent has a first activity against the target pest when applied without the formulation agent and the composition has a second activity against the target pest, and the second activity is greater than the first activity.Type: GrantFiled: April 26, 2024Date of Patent: February 10, 2026Assignee: TYRATECH, INC.Inventor: Essam Enan
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Patent number: 12539323Abstract: Provided herein are methods of treatment of psychiatric disorders requiring treatment with an antipsychotic drug, such as schizophrenia or schizoaffective disorder, comprising administration of both the antipsychotic drug and a W. somnifera plant part, extract, chemical constituent(s) thereof, or a derivative thereof to treat symptoms of the psychiatric disorder. Treatment is typically continued for at least four weeks. A combination dosage form comprising both the antipsychotic drug and the W. somnifera plant part, extract, chemical constituent(s) thereof, or a derivative thereof in amounts effective to treat the psychiatric disorder.Type: GrantFiled: December 1, 2021Date of Patent: February 3, 2026Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Kadiamada N. Chengappa, Dean Francis Salisbury
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Patent number: 12527820Abstract: A pharmaceutical composition is used for improving health, curing abnormalities and degenerative diseases, and achieving anti-aging therapeutic effect in mammals. The pharmaceutical composition includes a pharmaceutical carrier and an isotope selective component including at least one of a chemical element in which the isotopic ratio of at least one light isotope is altered to exceed natural abundance.Type: GrantFiled: May 29, 2024Date of Patent: January 20, 2026Assignee: Vector Vitale IP LLCInventors: Max Temnik, Sergey Gurin, Oleksandr Balakin, Peter Novak
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Patent number: 12527747Abstract: The embodiments relate to a pharmaceutically effective composition comprising sustained release particles, each sustained release particle comprising a shell and a core, wherein the shell comprises a first material and a second material, the second material comprising a first biodegradable material, wherein the core is enclosed by the shell and the core comprises a drug, wherein the first material is distributed in a matrix of the first biodegradable material, wherein the first material is configured to create holes in the shell and comprises metallic particles, wherein the holes allow the drug to be released to the exterior of the shell through the holes, and wherein the drug comprises a targeting material or targeting molecule that binds to a certain organ, object or a specific site within a body of a human or an animal.Type: GrantFiled: January 22, 2021Date of Patent: January 20, 2026Inventor: Neil S. Davey
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Patent number: 12502458Abstract: The invention is directed to biocompatible composite materials for medical applications such as tissue regeneration. In particular, the present invention is directed to biocompatible composite materials that may be used for the treatment of lost bone or bone defects. According to the invention there is provided an anhydrous biocompatible composite material comprising a biodegradable polymeric material and a granular synthetic material, wherein the polymeric material essentially consists of at least one block copolymer that comprises at least one hydrophilic block and at least one hydrophobic block.Type: GrantFiled: March 14, 2016Date of Patent: December 23, 2025Assignee: Kuros Biosciences B.V.Inventors: Florence De Groot-Barrere, Davide Barbieri, Dirk Wybe Grijpma, Joost De Bruijn