Abstract: Compositions comprising complexes of 1-methylcyclopropene and ?-cyclodextrin, and articles including the composition, are provided. Methods for using the compositions and articles in delaying the maturation of fruits, vegetables, and plants are also provided.
Type:
Grant
Filed:
January 3, 2022
Date of Patent:
July 23, 2024
Assignee:
Fresh Inset S.A.
Inventors:
Andrzej Wolan, Mariusz Bosiak, Marcin Pakulski, Lucyna Czajkowska, Katarzyna Anna Guranowska, Roksana Katarzyna Radlowska
Abstract: A purified exosome product includes spherical or spheroid exosomes with a diameter no greater than 250 nm. In some embodiments, the purified exosome product has a moisture content of no more than 10%. The purified exosome product can be reconstituted to prepare an artificial blood product.
Type:
Grant
Filed:
December 14, 2018
Date of Patent:
July 16, 2024
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors:
Atta Behfar, Soulmaz Boroumand, Michael V. Callahan
Abstract: An antimicrobial polymer for use in an ophthalmic implant, includes at least one antimicrobial monomer; and at least one other monomer selected from an acrylic, silicone, vinyl and collagen monomer.
Abstract: A preparation method for a modified nano-zinc oxide powder includes the following steps: step 1) immersing a raw material zinc oxide into a first active liquid, filtering and drying to obtain an activated zinc oxide; step 2) crushing the activated zinc oxide by an airflow crushing to obtain a crushed zinc oxide; step 3) immersing the crushed zinc oxide into the second active liquid, filtering, drying and grinding to obtain an activated nano-zinc oxide; and step 4) mixing the activated nano-zinc oxide and a surface modifier in a weight ratio of 1:(0.8-1.5) uniformly, drying and grinding to obtain a modified nano-zinc oxide powder with a particle size of 10-90 nm.
Abstract: The present invention relates to novel synergistic compositions comprising known “clean-label” antimicrobial substances as well as processes for stabilizing food substances against typical food borne spoilage microorganisms and/or pathogens. It is a further object of the invention to provide novel combinations of “clean-label” antimicrobials which may be employed in such a process.
Abstract: A pharmaceutical composition of the present invention is used for improving health, cure abnormalities and degenerative disease; achieve anti-aging effect of therapy and therapeutic effect on mammals. The pharmaceutical composition includes a pharmaceutical carrier and an isotope selective ingredient including at least one of a chemical element and a chemical compound containing the chemical element whereby isotope distribution in the at least one of the chemical element and the chemical compound containing the chemical element is different from natural distribution of at least one of isotopes wherein the part of selected isotope of the chemical element ranges from 0 to 100%. A method of the present invention uses the inventive pharmaceutical composition to improve health, cure abnormalities and degenerative disease and achieve therapeutic effect on mammals.
Type:
Grant
Filed:
October 19, 2022
Date of Patent:
June 18, 2024
Assignee:
Vector Vitale IP LLC
Inventors:
Peter Y. Novak, Maxim V. Temnikov, Oleksandr Balakin
Abstract: The invention provides a class of polymeric materials being ABA tri-block or AB di-block, comprised of biodegradable segments and poly(propylene oxide) (PPO) segment and uses thereof.
Type:
Grant
Filed:
December 31, 2015
Date of Patent:
June 11, 2024
Assignee:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
Abstract: The present technology generally relates to a pesticide-containing soil disinfestation material comprising: a polymer composite material; a coating material coating at least a portion of the polymer composite material; and non-volatile pesticides. The non-volatile pesticides are released in an amount to provide a concentration of between about 500 grams/hectare and about 5000 grams pesticides per hectare of soil.
Abstract: An antibacterial and antifungal polyester material is provided, which includes a polyester resin substrate material and a plurality of functional polyester master-batches. The functional polyester master-batches are dispersed in the polyester resin substrate material. Each of the functional polyester master-batches includes a polyester resin matrix material and an antibacterial and antifungal additive. The antibacterial and antifungal additive includes a plurality of glass beads. The glass beads are dispersed in the polyester resin matrix material, and a plurality of silver nanoparticles are distributed on an outer surface of each of the glass beads.
Type:
Grant
Filed:
February 15, 2022
Date of Patent:
April 30, 2024
Assignee:
NAN YA PLASTICS CORPORATION
Inventors:
Te-Chao Liao, Chun-Che Tsao, Yueh-Shin Liu
Abstract: Disclosed herein is a water system component including a substrate and a hydrophilic coating disposed on the substrate. The hydrophilic coating includes an adhesive agent; an insolubilizer for insolubilizing the adhesive agent; titanium dioxide; and a metal oxide selected from the group consisting of silver oxide, copper oxide, iron oxide, magnesium oxide, and combinations thereof.
Type:
Grant
Filed:
July 7, 2020
Date of Patent:
April 30, 2024
Assignee:
HAMILTON SUNDSTRAND CORPORATION
Inventors:
Barbara M. Peyton, Carol L. Metselaar, John W. Steele
Abstract: Methods of manufacturing a light-activated powder are provided which provide solid-state generation and release of chlorine dioxide without detectable amounts of any toxic by-products such as chlorine gas, chlorites, or chlorates. The powder need not be exposed to moisture, relative humidity, or an acid before or during exposure of the powder to visible light to generate the gas. The powder can also be prepared under conditions that minimize or prevent decomposition or oxidation of sodium chlorite or premature light activation of the powder during the manufacturing process to maximize its activity.
Type:
Grant
Filed:
February 22, 2022
Date of Patent:
April 16, 2024
Assignee:
Phiex Technologies, Inc.
Inventors:
Sumner Barenberg, Robert Cameron, Xiao Tian
Abstract: The current invention relates to modifying the surface of a cellulose-containing nonwoven substrate carrying a quaternary ammonium compound. A material for a nonwoven disinfecting wipe is provided which material includes a nonwoven substrate comprising cellulose and synthetic fibers and a combination of poly(vinylamine) and poly(amideamine-epichlorohydrin). Further, a method is provided for preparing a material for a nonwoven disinfecting wipe, the method comprising treating a nonwoven substrate comprising cellulose with poly(vinylamine) and poly(amideamine-epichlorohydrin).
Type:
Grant
Filed:
April 5, 2018
Date of Patent:
April 2, 2024
Assignee:
Suominen Corporation
Inventors:
Rui Ferreira, Muralidhar Lalagiri, Avinav G. Nandgaonkar
Abstract: Embodiments of the disclosure include coatings comprising an oligomerized polyphenol layer. The oligomerized polyphenol layer can be used as an intermediate coated layer on a medical device that hydrogen bonds to a synthetic or natural polymer, which in turn can be used as a top coat or further associated with another coated layer. The multilayered coatings can provide properties such as hemocompatibility or lubricity. In other embodiments, the oligomerized polyphenol layer is used on a medical device as a hemostatic layer configured to contact blood and promote coagulation. The oligomerized polyphenol layer can also be used on the inner surface (e.g., inner diameter) of a medical device to prevent bacterial adherence. The oligomerized polyphenol layer can also be used on the surface of a in vitro diagnostic article, or a cell culture device to, promote adsorption of a biological molecule.
Type:
Grant
Filed:
February 11, 2019
Date of Patent:
March 26, 2024
Assignee:
Surmodics, Inc.
Inventors:
David E. Babcock, Sean Lundquist, Gary Opperman, Adriyn Torguson, Tim Jentz
Abstract: A cerium oxide nanoparticle whose surface is covered with a vinyl polymer has a heterocyclic amine skeleton such as piperazine, pyridine, imidazole, or carbazole or with a polyamide having a heterocyclic amine skeleton such as piperazine, pyridine, imidazole, or carbazole; and a decomposition method of a nucleic acid or a polypeptide by using the cerium oxide nanoparticle.
Type:
Grant
Filed:
December 17, 2019
Date of Patent:
March 26, 2024
Assignee:
Toray Industries, Inc.
Inventors:
Shota Sekiguchi, Kazuhiro Matsuda, Takahiro Motoshiromizu, Masateru Ito
Abstract: In various aspects, the present invention is directed to novel bioactive peptide loaded poly(propylene fumarate) (PPF) tissue scaffolds and related methods for their making and use. In various embodiments, these bioactive peptide loaded poly(propylene fumarate) tissue scaffolds are formed by forming a PPF structure or matrix using photochemical 3-D printing techniques and then loading that printed PPF structure or matrix with a bioactive peptides or other bioactive compounds that have, or have been functionalized to have, a thiol functional group at or near its terminus. The thiol groups on the bioactive peptides or other compound will react with exposed alkene functional groups on the PPF polymer matrix via a thiol-ene “click” reaction, thereby binding these bioactive peptides or other compounds to the tissue scaffolds. The bioactive peptide loaded PPF tissue scaffolds of the present invention are particularly useful in repairing bone defects.
Abstract: A biodegradable based polymers for the production of biodegradable medical applications is provided. The biobased material has a copolymer constituted by dextran modified with glycidyl methacrylate and poly (#-caprolactone) modified with 2-isocyanatoethylmethacrylate, which are combined in different formulations and used to produce membranes, 3-D scaffolds and hollow tubes that can be used as biomedical devices for diverse applications, such as drug delivery systems, tissue engineering scaffolds, repair and regeneration of peripheral nerves, among others.
Type:
Grant
Filed:
June 6, 2019
Date of Patent:
March 19, 2024
Assignees:
UNIVERSIDADE DE COMIBRA, UNIVERSIDADE DO PORTO
Inventors:
Jorge Fernando Jordao Coelho, Ana Clotilde Amaral Loureiro Da Fonseca, Armenio Coimbra Serra, Ana Catarina Da Silva Pinho, Jose Domingos Santos, Ana Colette Pereira De Castro Osorio Mauricio, Ana Rita Caseiro Santos, Silvia Marlene Almeida Santos Pedrosa, Mariana Esteves Vieira Branquinho, Rui Damasio Alvites, Irina Ferraz Amorim Cruz
Abstract: The invention relates to a stable disinfectant composition and the use of said composition for spraying hatching eggs prior to in ovo vaccination, for disinfecting vaccination equipment including vaccination needles, and for flushing vaccination equipment post vaccination cycles.
Abstract: The invention relates to a scaffold material composition for forming a solid tissue scaffold, the composition comprising a plurality of hollow polymer pellets, each pellet comprising an open hollow extending through the pellet, and wherein the plurality of hollow polymer pellets are capable of interlinking and setting into a solid scaffold. The invention further relates to associated compositions, uses, method of treatment and kits associated with such material.
Type:
Grant
Filed:
February 12, 2018
Date of Patent:
February 20, 2024
Assignee:
LOCATE THEAPEUTICS LIMITED
Inventors:
Antonio Leonardi, Helen Celia Cox, Robin Andrew Quirk, Kevin Morris Shakesheff
Abstract: Methods for stimulating the growth, yield, and secondary metabolite production of Curcuma longa plants are provided. Administration of between about 2.5 mg/L and about 10 mg/L Moringa oleifera extract to Curcuma longa plants results in increased plant growth, rhizome production, and production of secondary metabolites including curcuminoids.
Type:
Grant
Filed:
September 5, 2023
Date of Patent:
February 20, 2024
Assignee:
KING FAISAL UNIVERSITY
Inventors:
Fadia El Sherif, Salah Khattab, Alaa Ahmed Ali Alamer, Yun Kiam Yap
Abstract: Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins.
Type:
Grant
Filed:
June 16, 2022
Date of Patent:
February 13, 2024
Assignee:
YALE UNIVERSITY
Inventors:
Yang Deng, Asiri Ediriwickrema, William M. Saltzman