Patents Examined by Kyle A Purdy
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Patent number: 12364726Abstract: The present invention refers to a composition for obtaining a natural bioactive for oncologic therapies based on Andrographis paniculata, whose excipient is phosphoryl ethanol amine, and optionally carbonates. The function of the composition is to assist treatments of several types of cancer, and it may be administered as an auxiliary adjuvant in oncologic therapies. Since it consists of diterpenoids, flavonoids and polyphenols as the main bioactive components, it has an anti-inflammatory, antiviral, antibacterial, antioxidant, antiparasitic, antispasmodic, antidiabetic, antipyretic, nematocidal, immunomodulatory and immunostimulatory action. The composition for obtaining a natural bioactive for oncologic therapies comprises: Active principle: Andrographis paniculata, and Excipient: phosphoryl ethanol amine. Optionally, the excipients are comprised of: Phosphoryl ethanol amine-Calcium Carbonate; and Magnesium Carbonate.Type: GrantFiled: December 13, 2022Date of Patent: July 22, 2025Inventor: Angelica Machado Mey
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Patent number: 12349681Abstract: In some embodiments, a composition includes a nitrogen fertilizer, a reactive oxygen species, and a reactive oxygen species inducer. An effective amount of the reactive oxygen species is sufficient to increase reactive oxygen species in a plant to induce increased nitrogen uptake efficiency by the plant and increased nitrogen utilization efficiency in the plant. In some embodiments, the reactive oxygen species inducer is a black walnut extract. In some embodiments, the reactive oxygen species inducer is hydrogen peroxide.Type: GrantFiled: October 9, 2023Date of Patent: July 8, 2025Assignee: RDX-N, LLCInventors: Darin Moon, Kody Moon
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Patent number: 12349675Abstract: Disclosed is a method for creating a composite colloidal particle formulation with advanced functionality that possesses highly efficient and effective properties. The composite colloidal particle formulation comprises an engineered biodegradable particle core dispersed in a bioadhesive polyelectrolyte solution. Also disclosed are methods of use of the same, including but not limited to applying said formulation to plants for disease treatment.Type: GrantFiled: December 23, 2020Date of Patent: July 8, 2025Assignee: BENANOVA INC.Inventor: Anka Veleva
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Patent number: 12336538Abstract: The present invention relates to a method for controlling undesired rats and mice comprising the steps of placing on a first day cholecalciferol baits at bait points in an environment to be protected and leaving the baits for a baiting time at the bait points, where the baiting time is less than 10 days for the control of mice and less than 15 days for the control of rats; or where the cholecalciferol baits are placed only on the first day of the baiting time and optionally on up to 3 further times within the baiting time in the environment to be protected.Type: GrantFiled: June 11, 2015Date of Patent: June 24, 2025Assignee: BASF AGRO B.V.Inventors: Thorsten Storck, Sharon Hughes
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Patent number: 12319828Abstract: Coating compositions, coated articles including the coating compositions, and methods of making the coating compositions and coated articles are provided. In some aspects, the coating compositions are applied to a substrate having nitric oxide-releasing properties. The coating compositions can include copolymers having crosslinking agents that can be activated with mild UV light (about 345 nm to 365 nm) to avoid damaging the substrate while creating strong covalent bonds to the substrate. The copolymers can include hydrophilic repeat units, and in particular zwitterionic repeat units such as repeat units containing phosphorylcholine groups. In some aspects, the coating compositions are applied to a surface of a polymer substrate, wherein the polymer substrate had nitric oxide releasing properties. The coating compositions and the coated articles can have antifouling, antithrombotic, and/or antibacterial properties.Type: GrantFiled: May 13, 2022Date of Patent: June 3, 2025Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.Inventors: Jason J. Locklin, Qiaohong Liu, Priyadarshini Singha, Hitesh Handa, Jitendra Pant, Marcus J. Goudie, Sean P. Hopkins
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Patent number: 12318491Abstract: A device for delivery of a therapeutic agent to a surgical cavity, including: a porous, mucoadhesive, freeze-dried polymeric matrix having first and second opposed surfaces, the matrix formed by a composition including chitosan; a plurality of particles embedded within the matrix, the particles containing the therapeutic agent and having a coating around the therapeutic agent, the coating including chitosan. The first surface of the matrix is configured to be applied to the surgical cavity; the device releases the particles through the first surface; the device is also sterilized and provides release of approximately 20% to 100% of the therapeutic agent within 20 minutes of application to the surgical cavity.Type: GrantFiled: December 15, 2023Date of Patent: June 3, 2025Assignee: PRIVO TECHNOLOGIES, INC.Inventors: Manijeh Nazari Goldberg, Brandon LaPorte, Aaron M. Manzi, Amani Jahjaa
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Patent number: 12296043Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: GrantFiled: November 30, 2023Date of Patent: May 13, 2025Assignee: Patheon Softgels Inc.Inventors: Yinyan Zhao, Yunhua Hu, Mervin Williams, Jr., Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus Gerardus Maria Van Duijnhoven, Martin Piest, Aqeel A. Fatmi
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Patent number: 12295981Abstract: Provided is a use of an Angelica gigas Nakai extract or a mixed extract of Angelica gigas Nakai and broccoli for the prevention and/or treatment of neurodegenerative diseases and/or amelioration, the protection of nerve cells and/or the generation of nerve cells.Type: GrantFiled: July 2, 2019Date of Patent: May 13, 2025Assignee: ASTROGENESIS CO., LTD.Inventors: Kang Hyun Lee, Min Kuk
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Patent number: 12295369Abstract: An article, and method of use, wherein the article includes: a substrate; a cationic coating bound to the substrate, wherein the cationic coating includes a guanidinyl-containing polymer that is crosslinked on the substrate; wherein the guanidinyl-containing polymer is of the following Formula (I), wherein: R3 is a H, C1-C12(hetero)alkyl, C5-C12(hetero)aryl, or Polymer; each R4 is independently H, C1-C12(hetero)alkyl, or C5-C12(hetero)aryl; each R5 is H, C1-C12(hetero)alkyl, C5-C12(hetero)aryl, or N(R4)2; Polymer is a residue of an aminopolymer chain; m is 1 or 2; and x is an integer of at least 1; and wherein the guanidinyl-containing polymer is crosslinked with an amine-reactive polyepoxy compound having pendant —OH groups.Type: GrantFiled: July 23, 2020Date of Patent: May 13, 2025Assignee: Solventum Intellectual Properties CompanyInventors: Andrew W. Vail, Jerald K. Rasmussen, Robert A. Schmitz
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Patent number: 12290547Abstract: A stamina-improving composition, a stamina-improving functional food including same and, more specifically, to a stamina-improving natural tea is provided. A stamina-improving composition including as an active ingredient at least one selected from Orostachys japonicus and Vigna vexillata var tsusimensis Matsumura is provided.Type: GrantFiled: March 7, 2022Date of Patent: May 6, 2025Inventor: Jong Hyun Nam
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Patent number: 12239135Abstract: An embodiment of the invention includes a handle-like mechanism configured to be continuously placed in contact with a plurality of different surfaces. A first copper material placed on an outside surface of the handle-like mechanism to be an intermediary surface between the handle-like mechanism and additional outside surfaces. A portion of the handle-like mechanism is not covered by the first copper material. A second copper material/adhesive is placed over the portion of the handle-like mechanism that is not covered by the first copper material to enable the handle-like mechanism to retain its intended function.Type: GrantFiled: March 19, 2021Date of Patent: March 4, 2025Inventor: Russell Kramer
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Patent number: 12225906Abstract: The sustenance of life is driven by recognition of and access to energy sources. This process has remained unchanged over billions of years, guiding cellular nutrition through molecular recognition, akin to the food pyramid. At the atomic or nanoscale, chemotaxis enables organisms to identify ingestible matter and is driven by their need for fuel, rather than from the sustenance itself. Chemotaxis, one of nature's most potent yet invisible organic forces, operates independently of molecular charge dynamics to locate and identify microscopic sustenance. Infectious organisms, such as pathogenic microbes and parasites, depend on chemotactic pathways to locate nutrition across all scales. This invention leverages this phenomenon by “baiting” these pathways with nutritive matter that encapsulates biocidal agents that are harmless to humans but lethal to infectious organisms once ingested.Type: GrantFiled: September 26, 2024Date of Patent: February 18, 2025Inventors: Terry Earl Brady, Anthony Lee Dellinger, Lowell Hughes, Melinda K. M. Goddard, Christopher E. Starr, Abed Alqader Ibrahim
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Patent number: 12213486Abstract: A process for preparing a biocidal, bactericidal and/or bacteriostatic material including the preparation of a polymer precursor solution that has (a) at least one monomer A having a porphyrin group and at least one radical polymerizable function, (b) at least one radical polymerizable monomer B, a photoinitiator, and (c) at least one of the monomers chosen from a monomer C having a quaternary amine and a radical polymerizable function; and/or a monomer D having copper and a radical polymerizable function. Also, the material obtainable by the process and its uses.Type: GrantFiled: December 19, 2019Date of Patent: February 4, 2025Assignees: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CONSERVATOIRE NATIONAL DES ARTS ET METIERS (CNAM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Thomas Berthelot, Céline Goulard-Huet, Fanny Hauquier
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Patent number: 12193445Abstract: A preparation method of a Pueraria lobata nano-silver composite hydrosol includes: dispersing Pueraria lobata powder in water, then heating to perform gelatinization, then adjusting a pH value, then sequentially adding an alkyl polyglucoside solution, a silver nitrate solution, and a sodium chloride solution, and performing a reaction by microwave heating to obtain the Pueraria lobata nano-silver composite hydrosol. The Pueraria lobata nano-silver composite hydrosol promotes seed germination of a Polygonatum Mill genus, and is applied in antibiotic detection and agricultural sterilization used as a fungicide.Type: GrantFiled: June 11, 2024Date of Patent: January 14, 2025Assignees: Jiangsu Vocational College of Agriculture and Forestry, Zhenjiang Zhaolong Agricultural Science and Technology Co., Ltd.Inventors: DaXiang Gao, FengTing Liu, GangJun Xi, Jun Shi, JiuLing Ding, HeTong Yang
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Patent number: 12179232Abstract: This invention provides a system and method for impregnating surfaces, which are typically porous and/or textile-based, with antiviral/antibacterial compounds in a manner that is robust, effective and straightforward. Such techniques can be employed during manufacture of the underlying item (e.g. PPE) and/or in the field. In an illustrative embodiment, a system and method for providing antiviral and antibacterial properties to a porous surface is provided. It includes a suspension consisting of a water-based solvent and an active ingredient consisting of at least one of a nanoparticulate metal and a chelated metal. The suspension is applied using an application process that immerses or sprays the suspension relative to the surface. Illustratively, the metal is at least one of silver, copper and titanium. Alternatively, or additionally, the metal can a chelated copper. The suspension can also include a salt component, such as sodium chloride. Additionally, the suspension can include a water repellant.Type: GrantFiled: April 28, 2021Date of Patent: December 31, 2024Assignee: Unique Equipment Solutions LLCInventor: Oleksandr Yuriiovych Mykytiuk
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Patent number: 12161720Abstract: Disclosed are therapeutic agent delivery vehicle comprising a modified platelet comprising a therapeutic agent cargo and a targeting moiety and methods for treating cancer comprising administering the same to a subject.Type: GrantFiled: April 8, 2019Date of Patent: December 10, 2024Assignee: North Carolina State UniversityInventors: Zhen Gu, Quanyin Hu
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Patent number: 12162972Abstract: The present disclosure relates, according to some embodiments, to photostable photoactive compositions comprising (a) at least one photoactive compound that develops within itself an excited state energy when subjected to UV radiation and (b) a block copolymer comprising a plurality of blocks, wherein the block copolymer is operable to quench the excited state energy.Type: GrantFiled: August 9, 2023Date of Patent: December 10, 2024Assignee: HALLSTAR BEAUTY AND PERSONAL CARE INNOVATIONS COMPANYInventors: Hui Feng, Shengkui Hu, Dennis Zlotnik
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Patent number: 12137691Abstract: The present invention relates to a method for treating plant seed in order to protect the growing seedling or plant against damping-off, coated plant seed, and the use of iron salt for coating plant seed to protect the growing seedling or plant against damping-off.Type: GrantFiled: July 8, 2020Date of Patent: November 12, 2024Assignee: RIJK ZWAAN ZAADTEELT EN ZAADHANDEL B.V.Inventors: Adriaan Verhage, Gerardus Johannes Maria Bijl, Frans Verheij
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Patent number: 12133876Abstract: In summary, the present disclosure is directed to a soft gel food supplement; formulated in eleven natural antiviral ingredients; to boost the immune system. The present disclosure contains natural antiviral antibacterial ingredients that makes the human immune system a more complex network of cells and proteins that defends the body against infection. The immune system keeps a record of every germ (microbe) it has ever defeated so it can recognize and destroy the microbe quickly if it enters the body again. Covid will attack everybody in its path. However, when a variant attempts to infect those who use the present disclosure dietary supplement formula and method, the immune system is nourished and ready to boost its normal function to the utmost in recognizing and destroying the virus and its variants efficiently.Type: GrantFiled: January 4, 2022Date of Patent: November 5, 2024Inventor: Peter Nguyen
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Patent number: 12114663Abstract: Provided are compositions and methods for use in deterring insects, such as aphids, from damaging plants. A method is provided and involves applying to one or more plants: i) bacteria that produce pyoverdine that emits fluorescent light that is detected by the insects and causes the insects to avoid the plant(s), wherein the bacteria are applied such that that there are more than 105 bacterial cells per 3 cm2 of plant surface, ii) a composition that contains at least 0.00005 mg of isolated pyoverdine that emits fluorescent light that is detected by the insects and causes the insects to avoid the plant(s), and combinations thereof. Also provided is a system for use in plant pest control in a confined space, including in structures such as greenhouses and hydroponic growing containers. The system includes one or more light sources that only emit light having a wavelength of 450-525 nm.Type: GrantFiled: February 11, 2019Date of Patent: October 15, 2024Assignee: Cornell UniversityInventor: Tory Hendry