Patents Examined by Lakshmi Channavajjala
  • 2-,5-,6-,7-,8-substituted oct-2-en-4-ones
    Patent number: 6723313
    Abstract: The invention relates to 2-,5-,6-,7-,8-substituted oct-2-en-4-ones, to a process for delivering these compounds as a fragrance, an aroma, or a flavoring, and to fragrance and aroma compositions prepared therewith.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: April 20, 2004
    Assignee: Givaudan SA
    Inventor: Philip Kraft
  • Hyaluronate lyase used for promoting penetration in topical agents
    Patent number: 6719986
    Abstract: The invention relates to an agent for treating skin diseases and/or functional disorders of the skin on the basis of different medicaments and/or auxiliary substances through promotion of penetration from topical formulations into the skin. According to the invention, the agent is composed of a hyaluronate lyase produced by microbial means and a medicament, preferably a hydrophilic medicament and/or auxiliary substances in different galenic formulations including colloidal carrier systems. The areas of application for the invention in human and veterinary medicament relate to the treatment, prophylaxis and/or metaphylaxis of skin diseases, functional disorders of the skin, the processes of skin ageing and dry skin conditions.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: April 13, 2004
    Assignee: esparma GmbH
    Inventors: Wolfgang Wohlrab, Reinhard Neubert, Christoph Huschka, Peter-Jürgen Müller, Jörg-Herman Ozegowski, Dieter Koegst, Gerhard Fries
  • Compositions for efficient release of active ingredients
    Patent number: 6716441
    Abstract: The present invention relates to a novel composition for efficiently releasing hydrophilic or water-soluble skin care actives from an oleaginous composition. The substantially oleaginous composition of the present invention comprises: (1) at least one skin care active; (2) a release agent having an HLB of at least about 3; and (3) a hydrophobic barrier protectant. The novel release composition may be topically applied to skin using a dispensing means such as an absorbent article, a wipe, a bandage, a pad, a canister, a stick, an aerosol dispenser, a sprayer, and the like.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: April 6, 2004
    Assignee: The Procter & Gamble Company
    Inventors: Scott Edward Osborne, George Endel Deckner, Thomas James Klofta, Victor Nicholas Vega
  • Ocular therapeutic agent delivery devices and methods for making and using such devices
    Patent number: 6713081
    Abstract: Ocular implant devices for the delivery of a therapeutic agent to an eye in a controlled and sustained manner. Dual mode and single mode drug delivery devices are illustrated and described. Implants suitable for subconjunctival placement are described. Implants suitable for intravitreal placement also are described. The invention also includes fabrication and implementation techniques associated with the unique ocular implant devices that are presented herein.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: March 30, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Michael R. Robinson, Karl G. Csaky, Peng Yuan, Cynthia Sung, Robert B. Nussenblatt, Janine A. Smith
  • Methods for treating photodamaged skin by administering selegiline or desmethylselegiline
    Patent number: 6709664
    Abstract: The present invention is directed to methods that can be used in the treatment of wounds, burns, and photodamaged skin. Methods can be used for both humans and animals and involve the administration of compositions containing selegiline and/or desmethylselegiline.
    Type: Grant
    Filed: August 8, 2002
    Date of Patent: March 23, 2004
    Assignee: Somerset Pharmaceuticals, Inc.
    Inventor: Mark G. Resnick
  • Hydrolytically stable esters
    Patent number: 6706259
    Abstract: The present invention deals with the certain novel esters derived from a specific 36 carbon diol and fatty acids, which unlike other esters are surprisingly stable to hydrolysis and consequently of interest in high and low pH applications.
    Type: Grant
    Filed: February 12, 2002
    Date of Patent: March 16, 2004
    Assignee: Phoenix Research Corp.
    Inventors: Bryce Gardner, John Imperante, Anthony J. O'Lenick, Jr.
  • Shampoo compositions comprising and emulsified silicone an a microemulsified silicone
    Patent number: 6706258
    Abstract: An aqueous shampoo composition comprising, in addition to water: i) at least one cleansing surfactant; ii) a cationic deposition polymer, and iii) a silicone component consisting of a blend of: (a) emulsified particles of an insoluble silicone, in which the emulsified particles of insoluble silicone are incorporated into the shampoo composition as a preformed aqueous emulsion having an average silicone particle size in the emulsion and in the shampoo composition of from 0.15 to 30 microns, and (b) microemulsified particles of an insoluble silicone, in which the microemulsified particles of insoluble silicone are incorporated into the shampoo composition as a preformed aqueous microemulsion having an average-silicone particle size in the microemulsion and in the shampoo composition of less than 0.10 microns.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: March 16, 2004
    Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.
    Inventors: Peter Gallagher, Tipawan Kreu-Nopakun, Andrew Malcolm Murray
  • Advances in towelettes containing organic carbonates
    Patent number: 6703033
    Abstract: Provided herein are moist towelettes useful for cleansing, among other things, hard surfaces and human skin. The moist towelettes of the invention comprise a towelette portion which is moistened with a liquid composition of matter wherein the liquid composition includes an alkylene carbonate as one of its components. According to one preferred form of the invention, the liquid composition from which the towelettes are made moist are alcohol-free. In another embodiment, a substantial portion of the alcohol in a given formulation is replaced with an alkylene carbonate component. Preferred alkylene carbonate components include propylene carbonate, butylene carbonate, and glycerine carbonate.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: March 9, 2004
    Assignee: Huntsman Petrochemical Corporation
    Inventors: Raeda M. Smadi, James R. Machac, Jr., Edward T. Marquis
  • Quinolone carboxylic acid compositions and related methods of treatment
    Patent number: 6699492
    Abstract: The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid compounds. The invention also relates to quinolone carboxylic acid compositions and methods of preparing the same.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: March 2, 2004
    Assignees: InSite Vision Incorporated, SSP Co., Ltd.
    Inventors: Samir Roy, Santosh Kumar Chandrasekaran, Katsumi Imamori, Takemitsu Asaoka, Akihiro Shibata, Masami Takahashi, Lyle M. Bowman
  • Methods for treating multiple sclerosis employing desmethylselegiline
    Patent number: 6699495
    Abstract: Methods and pharmaceutical compositions for using desmethylselegiline. In particular, the present invention provides novel compositions and methods for using desmethylselegiline for selegiline-responsive diseases and conditions. Diseases and conditions responsive to selegiline include those produced by neuronal degeneration or neuronal trauma and those due to immune system dysfunction. Desmethylselegiline is the R-(−) enantiomer of N-methyl-N-(prop-2-ynyl)-2-aminophenylpropane. Claimed compositions include both the R-(−) isomer and mixtures of the R-(−) and S(+) isomers. Pharmaceutically acceptable acid addition salts may also be used. Effective dosages are a daily dose of at least about 0.015 mg/kg of body weight.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: March 2, 2004
    Assignee: Somerset Pharmaceuticals, Inc.
    Inventors: Cheryl D. Blume, Anthony R. DiSanto
  • Quinolone carboxylic acid compositions and related methods of treatment
    Patent number: 6685958
    Abstract: The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid compounds. The invention also relates to quinolone carboxylic acid compositions and methods of preparing the same.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: February 3, 2004
    Assignees: InSite Vision Incorporated, SSP Co., Ltd.
    Inventors: Samir Roy, Santosh Kumar Chandrasekaran, Katsumi Imamori, Takemitsu Asaoka, Akihiro Shibata, Masami Takahashi, Lyle M. Bowman
  • Release-regulating preparations comprising biphenyldiamine derivatives
    Patent number: 6676968
    Abstract: A medicinal composition containing one or more compounds selected from the compounds represented by the following formula (I), salts of these compounds, solvates of these compounds and solvates of these salts and being capable of reducing the contact of the compounds with the components in the bile or pancreatic juice.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: January 13, 2004
    Assignee: Teijin Limited
    Inventors: Kiyoyuki Sakon, Masahiko Narasaki, Kentaro Fujinaga, Yoji Yamamoto, Hiroaki Mitsuhashi, Kazuoki Tsuruta, Hirofumi Tanabe, Yoshiaki Igarashi
  • Formulation for treatment of thromboembolism
    Patent number: 6673365
    Abstract: A new pharmaceutical formulation comprising the thrombin inhibitor HOOC—CH2—(R)-Cgl-Aze-Pab in combination with medium chain glycerides, a process for the preparation of such a pharmaceutical formulation, the use of a such formulation in the treatment of thromboembolism as well as a method of treating a patient in need of such a treatment by using said formulation.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: January 6, 2004
    Assignee: Astra Aktiebolag
    Inventors: Jan-Erik Löfroth, Lennart Lindfors, Anna-Lena Ungell
  • Colonic motor dysfunction remedies comprising aminothiazole derivatives as active ingredients
    Patent number: 6673368
    Abstract: Remedies effective for the improvement of colonic motor dysfunction such as irritable bowel syndrome, constipation or intestinal atony without causing side effects on the central nerve system. These colonic motor dysfunction remedies comprise, as active ingredients, aminothiazole derivatives represented by the following formula (I) or a salt or hydrate thereof: wherein R1, R2 and R3 may be the same or different and each independently represent a hydrogen atom or a hydroxyl, lower alkyl, lower alkoxy, amino, nitro or cyano group, R4 and R5 may be the same or different and each independently represent a hydrogen atom or a lower alkyl group, and n stands for an integer of from 2 to 4.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: January 6, 2004
    Assignee: Zeria Phamaceutical Co., Ltd.
    Inventors: Shigeru Ueki, Yuko Hori, Yugo Matsunaga, Masaaki Nagasawa, Hiroyasu Nishioka, Masakazu Murata
  • Method and compositions for coloring hair
    Patent number: 6669933
    Abstract: An aqueous hair color composition for oxidatively coloring hair in twelve minutes or less, wherein said composition is prepared by combining a dye mixture and a developer mixture, said aqueous hair color composition comprising 0.01-2.0% (combined weight) of the total composition of primary intermediates and couplers, a free alkalinity concentration of 0.20-0.75 meq/gram, and a hydrogen peroxide concentration of 4-6% by weight of the total composition; and a hair coloring kit containing separate containers of an aqueous dye mixture and an aqueous developing mixture for use with said dye mixture.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: December 30, 2003
    Assignee: Revlon Consumer Products Corporation
    Inventors: Dalal Ibrahim Esber Duffer, Louann Christine Vena, Minmin Tian, Shailendra Kumar Singh
  • Sustained-release prostaglandin I derivative preparation
    Patent number: 6656502
    Abstract: A sustained release preparation of prostaglandin I derivatives, which is highly safe and has stable drug-releasing and absorption properties, is disclosed. In the orally administrable preparation, the active component is a prostaglandin I derivative and the release-controlling component is a hydrogel base.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: December 2, 2003
    Assignee: Toray Industries, Inc.
    Inventors: Michio Hara, Yasuhide Horiuchi, Fuminori Tamura, Keishi Yamasaki
  • Treatment of skin with adenosine or adenosine analog
    Patent number: 6645513
    Abstract: Methods for enhancing the condition of non-diseased skin by application of compositions containing adenosine or an adenosine analog are disclosed. Also disclosed are methods for increasing DNA synthesis or protein synthesis in dermal cells, and methods for increasing dermal cell size, by application of compositions containing adenosine.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: November 11, 2003
    Assignee: University of Massachusetts
    Inventors: James G. Dobson, Jr., Michael F. Ethier
  • Transnasal anticonvulsive compositions and modulated process
    Patent number: 6627211
    Abstract: A method of vehicle modulated administration of an anticonvulsive agent to the nasal mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol, a glycol and a biological surfactant such as a bile salt or a lecithin. The pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration. Nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration. Such compositions are particularly suitable for a prompt and timely medication of patients in the acute and/or emergency treatment of status epilepticus and other fever-induced seizures.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: September 30, 2003
    Assignee: SK Corporation
    Inventors: Yong Moon Choi, Lianli Li, Kwon H. Kim
  • Thickened composition in aqueous medium and process for thickening aqueous medium
    Patent number: 6607714
    Abstract: A thickening system for aqueous medium, which can be used in the fields of cosmetics, dermatology or hygiene, comprising at least one amphiphilic polymer comprising at least one fatty chain and at least one hydrophilic unit, and at least one protein.
    Type: Grant
    Filed: September 17, 1996
    Date of Patent: August 19, 2003
    Assignee: L'Oreal
    Inventors: Christine Dupuis, Jean Mondet, Roland Audebert, Christophe Tribet
  • Solvent-based non-drying lipstick
    Patent number: RE38441
    Abstract: A long wearing, durable, non-smearing type wax based pigmented lipstick product including volatile solvents, non-volatile silicone polymer, oil soluble liquid phase and dry powder phase, is made to have improved moisturizing properties by incorporating a mixture of moisturizers which includes essential fatty acids provided by diisoarachidyl dilinoleate, fatty acid ester of &agr;-tocopherol, a cholesteryl/behenyl/octyldodecyl/lauroyl glutamate complex, and lauryl pyrrolidone carboxylic acid ester.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: February 24, 2004
    Assignee: Maybelline, Inc.
    Inventors: Terry Jacks, Brian Mattox