Patents Examined by Lakshmi Channavajjala
  • Nanoparticle isoflavone compositions and methods of making and using the same
    Patent number: 8551530
    Abstract: The present invention is directed to formulations of genistein and methods for making and using the same. In particular embodiments, the formulations described herein include suspension formulations of nanoparticulate genistein.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: October 8, 2013
    Assignee: Humanetics Corporation
    Inventors: Edmund Joseph Elder, Jr., Mark Joseph Sacchetti, Randall Joseph Tiachac, John L. Zenk
  • Use of acrylates copolymer as waterproofing agent in personal care applications
    Patent number: 8545859
    Abstract: The present invention relates to the use of acrylate copolymers, which provide excellent water resistance to personal care products without the undesirable waxy, greasy or heavy feel. Further, these acrylate copolymers are easy for manufacturers to use as they can be easily incorporated into the water phase without special processing.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: October 1, 2013
    Assignee: Akzo Nobel N.V.
    Inventors: Hongjie Cao, Gary T. Martino, Samuel A. Vona, Jr.
  • Oat extracts: refining, compositions and methods of use
    Patent number: 8512719
    Abstract: A simple and efficient method for the production of stable, clear, high-potency oat extracts is disclosed. The method employs the use of differential dissociation constants and ultrafiltration to stabilize extracts, prevent hazing, and prevent the loss of functional activity as an anti-irritant and anti-oxidant. Also disclosed are compositions of oat extracts derived from whole oat grains and oatmeal. Further disclosed are compositions of oat extracts for use in cosmetic, nutraceutical, therapeutic medical and veterinary preparations.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: August 20, 2013
    Assignee: Ceapro Inc.
    Inventors: Mark J. Redmond, David A. Fielder
  • Antiseptic compositions
    Patent number: 8512724
    Abstract: The present invention provides antiseptic compositions that contain DMSO or DMA, an alcohol (e.g., isopropanol), and/or an additional antiseptic agent such as iodine. In certain embodiments, the antiseptic compositions may be used for skin disinfection and/or skin antisepsis (e.g., as applied via a swab).
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: August 20, 2013
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Jeffrey J. Tarrand
  • Fragmented polymeric compositions and methods for their use
    Patent number: 8512729
    Abstract: Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and may be applied to target sites in a patient's body by extruding the hydrogel through an orifice at the target site. Alternatively, the hydrogels may be mechanically disrupted and used in implantable articles, such as breast implants. When used in vivo, the compositions are useful for controlled release drug delivery, for inhibiting post-surgical spinal and other tissue adhesions, for filling tissue divots, tissue tracts, body cavities, surgical defects, and the like.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: August 20, 2013
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Donald G. Wallace, Cary J. Reich, Narinder S. Shargill, Felix Vega, A. Edward Osawa, Zhen Qian-Wallis
  • Pharmaceutical formulation
    Patent number: 8506998
    Abstract: A solid, oral controlled release pharmaceutical dosage form has a water-soluble active ingredient dispersed in a matrix and releases the active ingredient at such a rate upon administration that the median tmax is 2.5 to 6 hours and the ratio of mean Cmax to mean plasma level of the active ingredient at 24 hours is in the range of 1.5 to 3.5.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: August 13, 2013
    Assignee: Euro-Celtique S.A.
    Inventors: Ronald Brown Miller, Stewart Thomas Leslie, Sandra Therese Antoinette Malkowska, Derek Allan Prater, Trevor John Knott, Hassan Mohammad
  • Regulation of mammalian hair growth
    Patent number: 8481015
    Abstract: The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: July 9, 2013
    Assignee: The Procter & Gamble Company
    Inventors: John Erich Oblong, Sara Johnson McPhail, Shannon Christine McArthur, Charles Carson Bascom, David Joseph Eickhoff, John McMillan McIver
  • Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
    Patent number: 8435562
    Abstract: Pharmaceutical compositions and oral dosage forms of (2R)-2-phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and methods of treating diseases comprising orally administering such pharmaceutical compositions and dosage forms are disclosed.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: May 7, 2013
    Assignee: XenoPort, Inc.
    Inventors: Chen Mao, Nikhil Pargaonkar, Laura E. Maurer, Sarina Grace Harris Ma
  • Oily base for a cosmetic and a cosmetic comprising the same
    Patent number: 8420109
    Abstract: The present invention provides an oily base for a cosmetic comprising an ester compound made from a multivalent alcohol and a fatty acid, characterized in that the ester compound is made from dipentaerythritol and at least one fatty acid selected from the group consisting of fatty acids having 5 to 16 carbon atoms and a molar ratio of a dipentaerythritol residue to a fatty acid residue having 5 to 16 carbon atoms in the ester compound is 1.0:3.0 to 1.0:6.0. The aforesaid oily base for a cosmetic has proper oily feeling with moistness, no uncomfortable sticky feeling, excellent safety to the skin and adhesion to the skin, excellent gloss-holding ability after application to the skin, and excellent compatibility with various oil agents. In addition, upon blending the ester compound in various cosmetics, the cosmetics also have proper emollient property.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: April 16, 2013
    Assignee: Kokyo Alcohol Kogyo Co., Ltd.
    Inventors: Naoki Sasaki, Yuki Kokeguchi, Kiyotaka Kawai
  • Ophthalmic oil-in-water emulsions containing prostaglandins
    Patent number: 8414904
    Abstract: The present invention refers to an oil-in-water emulsion for ophthalmic application comprising at least one prostaglandin as active agent and a surfactant component comprising a combination of at least two non-ionic surfactants. The emulsion is suitable for medical applications, particularly for the treatment of glaucoma, and has an increased chemical stability of the prostaglandin active agent so to allow long-term storage also at room temperature.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: April 9, 2013
    Assignee: AZAD Pharma AG
    Inventors: Fabio Carli, Mihran Baronian, Rene Schmid, Elisabetta Chiellini
  • Stable imatinib compositions
    Patent number: 8414918
    Abstract: Formulations containing imatinib, preferably imatinib mesylate, with high polymorphic stability and the processes for the preparation thereof are disclosed.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: April 9, 2013
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Bella Gerber, Zvika Doani
  • Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations
    Patent number: 8409612
    Abstract: A pharmaceutical formulation of a gastric proton pump inhibitor, with the exception of omeprazole, is disclosed. The formulation is in the form of microgranules insoluble in gastric fluid having improved stability over time. The formulation comprises several hydrophobic substances chosen in order to increase the stability of the active principle while obtaining the desired dissolution profile.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: April 2, 2013
    Assignee: Ethypharm
    Inventors: Bruno Criere, Pascal Suplie, Pascal Oury
  • Method for decreasing sebum production
    Patent number: 8409595
    Abstract: The present invention is directed to the topical application of the malonamide ACAT inhibitors described by Formula I. Other aspects of the invention are directed to topical formulations of these diamides, their use to treat sebaceous gland disorders and their use to alleviate oily skin.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: April 2, 2013
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Catherine R. Kostlan, Raj Neil Raheja, Meera Tugnait, Kimberly Wade
  • Process for cleaning hard gelatine capsules
    Patent number: 8409611
    Abstract: A process which can be used in the laboratory or on an industrial scale for cleaning the inner wall of hard gelatine capsules, in which the sealed capsules are cleaned with a powder formulation.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: April 2, 2013
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Herbert Wachtel, Petra Schmidt-Joerg, Volker Freudenberger
  • Vitamin powder composition and method of making
    Patent number: 8409617
    Abstract: A powder composition containing at least one fat-soluble vitamin dispersed in a matrix of a natural polysaccharide gum or a mixture of gums having an emulsifying capacity and/or a protein or a mixture of proteins having an emulsifying capacity. The fat-soluble vitamin in the powder compositions is in the form of droplets having an average diameter in the range of about 70 to about 200 nm. Tablets, beverages and beverage concentrates, foods, cosmetics and pharmaceuticals containing the powder composition can be made.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: April 2, 2013
    Assignee: DSM Nutritional Products Inc.
    Inventors: Chyi-Cheng Chen, Bruno Leuenberger
  • Gelled water-in-oil microemulsions for hair treatment
    Patent number: 8404218
    Abstract: The present invention provides a gelled water-in-oil microemulsion for hair treatment comprising: (a) an oil phase comprising: (i) a first oily component which is one or more glyceride fatty esters, and (ii) a second oily component which is one or more hydrocarbon oils of average carbon chain length less than 20 carbon atoms; (b) a hydrophilic phase comprising: (i) water, (ii) a nonionic emulsifier which is an ethoxylated alcohol having an HLB of at least 6, and (iii) preferably, a hair styling agent or hair conditioning agent, and (c) a gelling agent.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: March 26, 2013
    Assignee: Conopco, Inc.
    Inventors: Kelvin Brian Dickinson, Anand Ramchandra Mahadeshwar, Ruby Loo Bick Tan-Walker
  • Stabilisation of body-care and household products
    Patent number: 8404257
    Abstract: A description is given of the use of phenolic antioxidants of formulae (1) and/or (2) and/or (3) for stabilizing body-care and household products.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: March 26, 2013
    Assignee: BASF SE
    Inventors: Dietmar Hüglin, Thomas Ehlis, Erich Kramer, Joseph Anthony Lupia
  • Cosmetic agent
    Patent number: 8398963
    Abstract: The present invention relates to a cosmetic composition containing at least one water-soluble or water-dispersible polymer which has, in incorporated form, a) 5 to 50% by weight of an ?,?-ethylenically unsaturated monomer of the formula I ?where R1 and X1 are defined herein, b) 25 to 90% by weight an N-vinylamide and/or N-vinyllactam, c) 0.5 to 30% by weight of a compound having a free-radically polymerizable, ?,?-ethylenically unsaturated double bond and a cationogenic and/or cationic group per molecule, and d) 0 to 30% by weight of an ?,?-ethylenically unsaturated monomer of the formula II ?where R3, X2, and R4 are defined herein, and the salts thereof.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: March 19, 2013
    Assignee: BASF SE
    Inventors: Son Nguyen Kim, Claudia Wood
  • Agent for treating ulcer
    Patent number: 8372429
    Abstract: An agent for treating ulcer containing, as an effective component, a particulate composite hydrotalcite obtained by solidly dissolving a small amount of zinc in the particulate hydrotalcite, exhibiting excellent effect for treating the peptic ulcer and, further, working as a Zn-supplying agent. The agent for treating the ulcer is represented by the following formula (1), (MgaZnb)1-xAlx(OH)2(An?)x/n.mH2O??(1) wherein An? is CO32?, SO42? or Cl?, n is 1 or 2, and x, a, b and m are values that satisfy the following conditions, 0.18?x?0.4, 0.1?a<1, 0<b?0.5, 0?m<1.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: February 12, 2013
    Assignee: Kyowa Chemical Industry Co., Ltd.
    Inventors: Keiko Katsuki, Akira Okada
  • Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
    Patent number: 8367106
    Abstract: A pharmaceutical formulation of compounds with low aqueous solubility and method of manufacture thereof. The formulation may include a pharmacologically active compound having low aqueous solubility and starch in the amount of greater than about 25 weight percent. A manufacturing method may include blending the active compound and starch, compressing the blend into a solid, comminuting the solid into granules, wetting the granules, drying the granules, and tabletting the dried granules to make a solid pharmaceutical formulation.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: February 5, 2013
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Ilan Zalit, Fanny Leska, Mali Kadosh, Dorit Marco, Yonit Messer-Triger