Patents Examined by Laura Schell
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Patent number: 10238849Abstract: Disclosed are a sonotrode and its use for transdermal delivery of therapeutic or cosmetic compounds. The sonotrode 10 comprises a tubular neck 14 attached at a proximal end to a solid head 12 and ending at a distal end in a flared foot 16. When coupled to an ultrasonic transducer and applied to skin of a human or animal, the sonotrode enhances the delivery of compounds into the skin.Type: GrantFiled: July 30, 2010Date of Patent: March 26, 2019Inventors: Alexander Britva, Alexander Dverin, Yevgeny Pens, Ziv Karni
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Patent number: 10232173Abstract: Devices and methods for delivering an electropermeabilizing pulse of electric energy to a tissue surface to enable delivery into cells in the tissue therapeutic substances. The device incorporates a source capable of generating a sufficient voltage potential to deliver a spark across a gap and delivers same to the tissue surface.Type: GrantFiled: April 16, 2010Date of Patent: March 19, 2019Assignee: VGX Pharmaceuticals, LLCInventors: Thomas Joseph Kardos, Stephen Vincent Kemmerer, Rune Kjeken, Kate Broderick, Jay McCoy, Michael P Fons
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Patent number: 10220004Abstract: A method for controlled delivery of a substance into a body includes administering a plurality of containment vessels into the body, in which each of the plurality of containment vessels includes a quantity of the substance loaded therein prior to the administering; and providing a time-varying magnetic field such that the plurality of containment vessels are exposed thereto to cause a release of at least a portion of the substance from the plurality of containment vessels. Each of the plurality of containment vessels has an average outer diameter less than about 1 ?m.Type: GrantFiled: July 16, 2012Date of Patent: March 5, 2019Assignee: The Regents of the University of CaliforniaInventors: Jeffrey I. Zink, Courtney R. Thomas, Monty Liong, Sarah Ann Henscheid, Jinwoo Cheon, Jae-Hyun Lee, Daniel P. Ferris
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Patent number: 10188410Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.Type: GrantFiled: January 8, 2008Date of Patent: January 29, 2019Assignee: EKOS CORPORATIONInventors: Azita Soltani, Kim R. Volz
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Patent number: 10182833Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.Type: GrantFiled: July 9, 2008Date of Patent: January 22, 2019Assignee: EKOS CORPORATIONInventors: Azita Soltani, Kim R. Volz
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Patent number: 10173043Abstract: An anchoring mechanism and method for anchoring a device within a biological conduit include an expandable element configured for retaining the device at a desired angle relative to a central axis of the biological conduit. A steering mechanism is preferably provided for orienting the device prior to operation of the anchoring mechanism. The anchoring mechanism and method are employed in drug delivery devices, brachytherapy devices or for anchoring a catheter or sheath to provide a working channel for reliable guidance of a wide range of tools to a target location within the body.Type: GrantFiled: May 18, 2012Date of Patent: January 8, 2019Assignee: COVIDIEN LPInventor: Dorian Averbuch
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Patent number: 10169540Abstract: The present invention provides a blood glucose system for treating a glucose metabolic disorder. The system includes a dosing device having a counter for generating a count and memory for storing dose quantities and counts, a blood glucose measuring device having memory for storing blood glucose measurements and measurement times, and a data processor for receiving data from the dosing device and blood glucose measuring device and converting counts to actual times. The data processor synchronizes the counts with the measurement times using a time standard.Type: GrantFiled: December 19, 2008Date of Patent: January 1, 2019Assignee: Roche Diabetes Care, Inc.Inventors: Matthias Köhler, Peter Blasberg
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Patent number: 10166334Abstract: A medicine injector in which a barrel with a receiving cavity is adapted to slidably receive a syringe subassembly for axial movement therein. Upon removal of a safety and release of a syringe driver, the syringe driver moves forward and injects the syringe needle. Penetration controls are shown for controlling needle penetration depth. In one form the penetration control uses a sleeve and spring which are radially adjacent. A cushioning ring or other cushion may be used to reduce syringe breakage. A load distribution and guide ring may be used to distribute loading applied to the syringe and help guide the moving syringe.Type: GrantFiled: September 29, 2009Date of Patent: January 1, 2019Assignee: Washington Biotech CorporationInventor: Ronald E. Wyrick
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Patent number: 10149941Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end with a passageway therethrough in fluid communication with the chamber. An elongate plunger having a proximal end, a distal end and a flexible stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for drawing fluid into and out of the chamber by movement of the stopper relative to the barrel. The barrel includes anti-reflux structure for holding said stopper in a partially deflected position after fluid has been delivered from the chamber and the stopper is being force against the distal end of the chamber.Type: GrantFiled: May 27, 2015Date of Patent: December 11, 2018Assignee: Becton, Dickinson and CompanyInventors: Thomas A. Alheidt, Tracy Ray Hottovy, Dustin Drake
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Patent number: 10123938Abstract: A fluid transfer assembly, drug container, and method for enabling fluid transfer in an infusion system is taught. The assembly includes a fluid container containing an infusion fluid, and a drug container. The fluid container has at least one inlet port for receiving a medical substance from the drug container. The assembly further includes at least one fluid barrier controlling fluid passage between the drug container and the fluid container. The inlet port exhibits a first luer-lock connector, and the drug container is sealed by a cap exhibiting a second luer-lock connector for attachment to the first luer-lock connector. The fluid barrier is designed and arranged to be ruptured by an external force to allow the fluid passage.Type: GrantFiled: September 11, 2013Date of Patent: November 13, 2018Assignee: Carmel Pharma ABInventors: Roger Akerlund, Kjell Andreasson, Petri Horppu
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Patent number: 10085783Abstract: The present disclosure relates to devices for injecting material into a body. The devices include a housing having a deployment cannula extending therefrom. The device also includes a rotary drive member wherein rotational movement of the drive member relative to the housing results in linear movement of an elongated injection member within a lumen of and out of a distal end opening of the deployment cannula. The elongated injection member includes a proximal end portion that may have a Tuohy-Huber tip and/or varying radii therealong.Type: GrantFiled: March 14, 2013Date of Patent: October 2, 2018Assignee: IZI MEDICAL PRODUCTS, LLCInventors: Jeffrey L. Emery, Laurent Schaller, Ryan J. Connolly, Andrew Huffmaster, Ebrahim M. Quddus, Timothy J. McGrath, Sean M. Tutton
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Patent number: 10064990Abstract: Syringe assemblies comprising a first cap and a second cap to ensure sterilization of the fluid path without the need for external packaging are described. Also described are methods of sterilizing the fluid path of a syringe assembly.Type: GrantFiled: July 16, 2012Date of Patent: September 4, 2018Assignee: Becton, Dickinson and CompanyInventor: Anil Sodhi
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Patent number: 10052471Abstract: An access port for providing subcutaneous access to a patient is disclosed. The access port includes a septum including palpable identification indicia thereon. In particular, the access port in one embodiment includes a body that defines a fluid cavity and a needle-penetrable septum covering the fluid cavity for providing access thereto. The septum defines an outer periphery. One or more palpation features are included on the septum. The palpation features each include a portion that extends in a radial direction beyond the outer periphery of the septum. The palpation features are therefore disposed relatively farther away from each other, simplifying palpation and identification thereof after the port has been subcutaneously implanted into a patient. The palpation features can be indicative of an attribute of the port, such as its ability to withstand fluid pressures and flow rates associated with power injection, for instance.Type: GrantFiled: December 31, 2014Date of Patent: August 21, 2018Assignee: C. R. Bard, Inc.Inventors: Bret Hamatake, John G. Evans
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Patent number: 10022504Abstract: A pen needle (101) for use with a drug delivery device (100) includes a hub body (113) having internal threads (216) to receive the drug delivery device (100). A post (121) is connected to the hub body (113). A needle (103) is rigidly fixed to the post (121). The post (121) is separable from the hub body (113) such that the needle (103) is removed with the post (121). The fluid path is not disturbed by such removal because the entire needle (103) is removed with the post (121). Removal of only the post (121) and needle (103) reduces the volume of waste required for disposal, thereby increasing the effective capacity of a sharps container.Type: GrantFiled: September 15, 2010Date of Patent: July 17, 2018Assignee: Becton, Dickinson and CompanyInventors: Joshua Horvath, Joseph Brizzolara, Charles Hwang, James Bates, Keith Knapp
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Patent number: 10016561Abstract: A computer implemented method of determining a clinical variables utilizing an insulin pump that includes initiating blood glucose measurements, initiating ingestion of carbohydrates and receiving input data based on the blood glucose measurements and the ingestion of carbohydrates and utilizing the data to calculate clinical variables. The invention may include presenting instructions to a patient to take various actions and to input various data. The clinical variables determined may be stored in memory and then used to calculate insulin doses and to send a signal to an insulin pump to infuse the insulin dose calculated.Type: GrantFiled: March 15, 2013Date of Patent: July 10, 2018Assignee: Tandem Diabetes Care, Inc.Inventors: Sean Saint, Mike Rosinko
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Patent number: 9968760Abstract: Device for fixing and protecting a needle, this device having a first and a second adhesive part, separated by a central part, the first part being intended to be fixed to the skin, opposite the chosen penetration site for the needle, only one of the faces of the first part being adhesive, and a cutting line defining two longitudinal arms, each of these two arms including an outermost part belonging to the second adhesive part.Type: GrantFiled: June 29, 2009Date of Patent: May 15, 2018Assignee: NEPHROKITInventor: Mokhtar Chawki
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Patent number: 9958067Abstract: A syringe for dispensing liquid materials to a substrate. In one embodiment, the syringe includes a barrel having a first end, a second end, and an interior reservoir. A piston is slidably disposed within the reservoir and is movable to increase or decrease a volume of the interior reservoir near the first end of the barrel. A first end of the piston has a hemispherically-shaped surface profile, with an elongated apex extending therefrom, to dispense liquid from the first end of the barrel when the piston is moved in a direction toward the first end.Type: GrantFiled: June 12, 2007Date of Patent: May 1, 2018Assignee: Nordson CorporationInventors: Warren N. Strong, Michael A. Vidal, Terrence Woldorf
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Patent number: 9764094Abstract: Syringes and methods of using are described which protect materials within the syringe barrel cavity from contaminants and photo-chemical degradation. A syringe is provided having an inspection window for viewing medications or other materials within the cavity of a syringe barrel. The syringe barrel and other syringe components may be colored, opaque, darkened, amber, tinted; or the syringe barrel may have applied thereto polarizing filters; or materials having light polarizing properties can be used to manufacture the syringe barrel and other syringe components of the syringe to cancel particular components of light.Type: GrantFiled: June 4, 2014Date of Patent: September 19, 2017Inventor: Robin Scott Gray
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Patent number: 9744343Abstract: An access portal is provided including a housing, a body defining a fluid reservoir, and a septum enclosing the fluid reservoir. A stem in fluid communication with the fluid reservoir extends from the fluid reservoir. The access portal also includes a reservoir insert disposed within the fluid reservoir, in which the reservoir insert decreases the fluid fill volume of the reservoir.Type: GrantFiled: May 22, 2012Date of Patent: August 29, 2017Assignee: Primo Medical Group, Inc.Inventor: Kenneth Arden Eliasen
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Patent number: 9744139Abstract: An ingestible capsule (10) is provided for delivery of a drug, the capsule (10) comprises a first module (11) and a second module (12). The first module (11) has at least one drug compartment (13) for comprising an amount of the drug. The drug compartment (13) is sealed by a foil (14) with an embedded conducting heating wire (15). The second (12) module comprises electronics (18) for providing an electrical pulse to the heating wire (15) in order to open the drug compartment (13) by melting the foil (14). The first module (11) and second module (12) comprise interoperable connection means (19) for securing the first module (11) to the second module (12) such that the heating wire (15) is electronically coupled to the electronics (18).Type: GrantFiled: April 2, 2010Date of Patent: August 29, 2017Assignee: Stoco 10 GmbHInventors: Johan Frederik Dijksman, Anke Pierik, Frits Tobi De Jongh, Jeff Shimizu, Hans Zou, Lucian Remus Albu, Olaf Weiner